Prognostic Factors Affecting Teeth in the Line of Mandibular Fractures

1990 ◽  
Vol 7 (4) ◽  
pp. 7-9 ◽  
Author(s):  
J. Alexander ◽  
Sandra Manfra Marretta
Keyword(s):  
Prognostic Factors ◽  
Fracture Line ◽  
Treatment Modalities ◽  
Mandibular Fractures ◽  
Review Of The Literature ◽  
Factors Affecting ◽  
Controversial Topic ◽  
New Treatment

Historically, the treatment of teeth in the line of mandibular fractures has been a controversial topic. Teeth in the line of mandibular fractures initially were extracted. With the advent of antibiotics, the decision to routinely extract all involved teeth was questioned. The question to retain or extract teeth in the fracture line is addressed following a review of the literature. Recommendations for assessing teeth in the fracture line based on new treatment modalities are included in this review.

Pretreatment prognostic factors associated with outcomes for first-line FCR-based treatments in previously untreated CLL.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 6517-6517
Author(s):  
William G. Wierda ◽  
Susan Mary O'Brien ◽  
Stefan Faderl ◽  
Alessandra Ferrajoli ◽  
Jan Andreas Burger ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
High Risk ◽  
Performance Status ◽  
Absolute Lymphocyte Count ◽  
Patient Characteristics ◽  
Treatment Modalities ◽  
First Line ◽  
Liver Size ◽  
Improved Outcomes ◽  
New Treatment

6517 Background: First-line chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab (FCR) demonstrated improved outcomes, including survival, for fit patients (pts) with CLL. Modifications of this regimen, including intensified rituximab (FCR3), addition of mitoxantrone (FCMR) or addition of alemtuzumab fir high-risk CLL (CFAR), were evaluated but did not improve outcomes in historic comparisons. Methods: We correlated outcomes, including complete remission (CR), time-to-treatment failure (TTF) and overall survival (OS), with new and traditional pretreatment prognostic factors to identify high-risk pts. Results: All pts (N=473) had an NCI-WG indication for treatment and received a first-line FCR-based regimen on trial; the intended treatment was 6 courses. Patient characteristics correlated with outcomes are presented in the table. Factors not associated with outcomes included absolute lymphocyte count; platelet count; performance status; spleen size; liver size; and number of involved lymph node sites. Conclusions: We identified the following as high-risk pretreatment features for patients going on first-line FCR-based therapy: advanced age, presence of 17p del, high B2M (≥4mg/l), and unmutated IGHV gene. Pts with these features should be pursued with new treatment modalities and novel agents in order to improve outcomes. [Table: see text]

Accidental Intra-Arterial Injection: A Case Report, New Treatment Modalities, and a Review of the Literature

2006 ◽  
Vol 64 (6) ◽  
pp. 965-968 ◽  
Author(s):  
John R. Keene ◽  
Karen M. Buckley ◽  
Stephen Small ◽  
Gerald Geldzahler
Keyword(s):  
Case Report ◽  
Treatment Modalities ◽  
Review Of The Literature ◽  
New Treatment

scholarly journals A retrospective study of 109 dogs with mandibular fractures

2013 ◽  
Vol 26 (01) ◽  
pp. 01-05 ◽  
Author(s):  
H. de Rooster ◽  
S. M. Ferreira ◽  
G. Steenkamp ◽  
A. M. Kitshoff
Keyword(s):  
South Africa ◽  
Treatment Options ◽  
Small Animal ◽  
Fracture Morphology ◽  
Mandibular Fracture ◽  
Fracture Repair ◽  
Fracture Line ◽  
Mandibular Fractures ◽  
Anatomical Location ◽  
New Treatment

SummaryObjective: To determine patient factors and fracture morphology of dogs presented with mandibular fractures to a small animal referral centre in South Africa.Methods: Patient data on age, sex, breed and aetiology of dogs with mandibular fractures were recorded. The fractures were classified according to the anatomical location, displacement, fracture type, fracture line direction, periodontal pathology, and whether there were teeth in the fracture line or not by evaluation of preoperative radiographs. Clinical observations indicated whether these fractures were open or closed.Results: In total, 109 dogs with 135 mandibular fractures were included in the study. Small breed dogs and dogs less than eight months of age predominated (102/109). Dog fights were the most common aetiology in this study (68/109). The molar region was the most commonly affected region (56/135). Evaluation of the radiographs revealed that transverse (73/135), relatively unstable (116/135), and displaced (112/135) fractures were the most common. The majority of fractures involved teeth in the fracture line (100/135), with the first molar frequently involved (54/135). The majority of fractures were open (104/135).Clinical significance: The results obtained from this study may be used to guide patient and fracture morphology selection in biomechanical studies of mandibular fracture repair techniques. Screening of this patient population may inspire the search for new treatment options for mandibular fracture repair in South Africa.

scholarly journals Primary Immune Thrombocytopenia and Essential Thrombocythemia: So Different and yet Somehow Similar—Cases Series and a Review of the Literature

2021 ◽  
Vol 22 (20) ◽  
pp. 10918
Author(s):  
Marta Sobas ◽  
Maria Podolak-Dawidziak ◽  
Krzysztof Lewandowski ◽  
Michał Bator ◽  
Tomasz Wróbel
Keyword(s):  
Essential Thrombocythemia ◽  
Immune Thrombocytopenia ◽  
Treatment Modalities ◽  
Review Of The Literature ◽  
Thrombocytopenic Purpura ◽  
Cytokine Modulation ◽  
Primary Immune Thrombocytopenia ◽  
New Treatment ◽  
Sequential Appearance

This article collects several published cases in which immune thrombocytopenic purpura (ITP) is followed by essential thrombocythemia (ET) and vice versa. This surprising clinical condition is possible, but very rare and difficult to diagnose and manage. We have made an attempt to analyse the possible causes of the sequential appearance of ITP and ET taking into consideration the following: alteration of the thrombopoietin (TPO) receptor, the role of autoimmunity and inflammation, and cytokine modulation. A better understanding of these interactions may provide opportunities to determine predisposing factors and aid in finding new treatment modalities both for ITP and ET patients.

Adult cerebellar glioblastoma: case report and review of the literature/strong

2020 ◽  
Vol 8 (1) ◽  
pp. 1-12
Author(s):  
Gabriel Castelluccio ◽  
Gonzalo Bertullo
Keyword(s):  
Systematic Review ◽  
Brain Tumor ◽  
Prognostic Factors ◽  
Case Report ◽  
Primary Brain Tumor ◽  
Treatment Modalities ◽  
Pathological Features ◽  
Review Of The Literature ◽  
Clinical Hospital ◽  
Cerebellar Glioblastoma

Glioblastoma is the most common and malignant primary brain tumor but its occurrence in the cerebellum is very rare. Giving its low occurrence the treatment modalities and outcome of this glioblastoma location are still poorly understood. We present the case of an adult woman with a cerebellar glioblastoma treated at the Clinical Hospital of Montevideo, and we perform a non-systematic review of the literature concerning the clinical, radiological and pathological features of this tumor, as well as its treatment modalities, prognostic factors and outcome.

Management of thoracic aortic lesions - the future is endovascular

VASA ◽  
2012 ◽  
Vol 41 (3) ◽  
pp. 163-176 ◽  
Author(s):  
Weidenhagen ◽  
Bombien ◽  
Meimarakis ◽  
Geisler ◽  
A. Koeppel
Keyword(s):  
Thoracic Aorta ◽  
Clinical Decision Making ◽  
Treatment Options ◽  
Clinical Decision ◽  
Clinical Results ◽  
Treatment Modalities ◽  
Traumatic Rupture ◽  
Descending Thoracic Aorta ◽  
New Treatment ◽  
Aneurysm Dissection

Open surgical repair of lesions of the descending thoracic aorta, such as aneurysm, dissection and traumatic rupture, has been the “state-of-the-art” treatment for many decades. However, in specialized cardiovascular centers, thoracic endovascular aortic repair and hybrid aortic procedures have been implemented as novel treatment options. The current clinical results show that these procedures can be performed with low morbidity and mortality rates. However, due to a lack of randomized trials, the level of reliability of these new treatment modalities remains a matter of discussion. Clinical decision-making is generally based on the experience of the vascular center as well as on individual factors, such as life expectancy, comorbidity, aneurysm aetiology, aortic diameter and morphology. This article will review and discuss recent publications of open surgical, hybrid thoracic aortic (in case of aortic arch involvement) and endovascular repair in complex pathologies of the descending thoracic aorta.

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