The Prognostic Value of Post-Treatment Retinopathy after Panretinal Photocoagulation for Proliferative Diabetic Retinopathy in Type 1 Diabetes

2004 ◽  
Vol 14 (6) ◽  
pp. 538-542 ◽  
Author(s):  
T. Bek ◽  
J. Kjærgaard
2011 ◽  
Vol 46 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Bashira A. Charles ◽  
Yvette P. Conley ◽  
Guanjie Chen ◽  
Rachel G. Miller ◽  
Janice S. Dorman ◽  
...  

2015 ◽  
Vol 53 (3) ◽  
pp. 261-266 ◽  
Author(s):  
Irina Duţă ◽  
Simona Fica ◽  
Daniela Adriana Ion

Abstract Introduction. Little is known about the relationship between insulin resistance and proliferative diabetic retinopathy in type 1 diabetes. The aim of this article is to explore the relationship between sight-threatening proliferative diabetic retinopathy and insulin resistance. Methods. This was a cross-sectional study that included 167 type 1 diabetes patients. Insulin resistance was assessed using eGDR (estimated glucose disposal rate) formula. Diabetic retinopathy was assessed by ophthalmoscopy using Early Treatment Diabetic Retinopathy classification. The association between eGDR and proliferative diabetic retinopathy was assessed in uni- and multivariate models using stepwise logistic regression of covariates. The contribution of individual predictors in the final regresion model was examined using Wald statistic. Results. Significantly lower eGDR’s values were observed in patients with proliferative diabetic retinopathy: 5.5 vs. 7 (p = 0.002). The results remained significant (p < 0.001) after adjusting for multiple covariates (sex, diabetes duration, body mass index, HDL cholesterol, LDL cholesterol, triglycerides, smoking). eGDR variable was retained in the final model of stepwise logistic regression (p < 0.001) and showed the strongest association with proliferative diabetic retinopathy (Wald = 12.73). Conclusions. In type 1 diabetes patients insulin resistance was the most important independent risk factor associated with diabetic proliferative retinopathy.


Reflection ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 36-42
Author(s):  
O.V. Kolenko ◽  
◽  
Y.B. Lebedev ◽  
A.Y. Khudyakov ◽  
E.L. Sorokin ◽  
...  

Aim. To investigate the technical difficulties of performing the stages of vitreoretinal surgery, the peculiarities of the surgical technique in young patients with the proliferative stage of diabetic retinopathy (DR). Methods. Twelve patients (12 eyes) with type 1 diabetes mellitus (DM) were selected. Their average age was 26±2 years (from 19 to 30 years). There were 4 men and 8 women. All patients had DM since childhood. Selection criteria: presence of indications for vitreoretinal surgery for proliferative DR, age of patients with type 1 DM not more than 30 years, onset of DM in childhood. Results. Initially, the clinical manifestations of proliferative DR in young people with type 1 DM were distinguished by the severity of neovascular and fibrous growths, a tendency to hemorrhages, and the complexity of preoperative preparation in the form of panretinal laser coagulation, at least partial. Surgical removal of vitreoretinal adhesions and elimination of neovascularization zones differed in technical difficulties associated with their higher density and the area of retinal tissue lesion. Conclusion. Surgical treatment of proliferative DR in young patients has a number of technical difficulties associated with the density and length of fibrovascular vitreoretinal growths, the difficulty of separating them due to the high tendency of newly formed vessels to hemorrhages. Key words: proliferative diabetic retinopathy; endovitreal surgery; type 1 diabetes mellitus; young age.


Endocrine ◽  
2019 ◽  
Vol 66 (2) ◽  
pp. 201-209 ◽  
Author(s):  
Rita Laiginhas ◽  
Carolina Madeira ◽  
Miguel Lopes ◽  
João Sérgio Neves ◽  
Margarida Barbosa ◽  
...  

2013 ◽  
Vol 230 (1) ◽  
pp. 50-54 ◽  
Author(s):  
Mie Gaedt Thorlund ◽  
Mette Borg Madsen ◽  
Anders Green ◽  
Anne Katrin Sjølie ◽  
Jakob Grauslund

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