Blood sampling from peripherally inserted central catheter is effective and safe for patients with head and neck cancers

2020 ◽  
pp. 112972982094345
Author(s):  
Yuejiao Zhang ◽  
Shoude Zhang ◽  
Jinhua Chen ◽  
Ruiyi Zhao
Keyword(s):  
Head And Neck ◽  
Blood Stream Infection ◽  
Blood Stream ◽  
Blood Sampling ◽  
Peripherally Inserted Central Catheter ◽  
Test Results ◽  
Central Catheter ◽  
Blood Samples ◽  
Numerical Rating ◽  
Analogue Scales

Objective: To evaluate the validity of laboratory tests for blood sampling from a peripherally inserted central catheter. Methods: A total of 22 patients diagnosed with head and neck cancers were enrolled. In total, 101 paired blood samples were taken both via venipuncture and peripherally inserted central catheter for hematology and biochemistry testing. Paired t tests and linear correlation analysis were used to evaluate the results. Blood sampling–related pain was recorded by visual analogue scales and numerical rating scales. Infusion occlusion, hemolysis, and catheter-related blood stream infection were also recorded. Results: The peripherally inserted central catheter–associated test results were slightly lower than those with venipuncture. Some parameters differed more than others. However, the degree of difference was less than 5% for every pair. There was a high correlation between the test results with two methods of blood sampling with the representative equation approximately being “y = x.” According to visual analogue scales and numerical rating scale analysis, the pain degree with peripherally inserted central catheter was significantly lower than that of the venipuncture (p < 0.001). No case of infusion occlusion, catheter-related blood stream infection was reported with both methods. Hemolysis rate in blood samples from peripherally inserted central catheter (1/101) was much lower than that seen with venipuncture (11/101) with significant difference (p = 0.0056). Conclusion: Blood sampling via peripherally inserted central catheter and venipuncture showed equivalent reliability in laboratory testing. Compared with venipuncture, blood sampling via peripherally inserted central catheter causes less pain and is safer. Blood sampling via peripherally inserted central catheter is strongly recommended for clinical use.

Comparing catheter related bloodstream infection rate between cuffed tunnelled and non-cuffed tunnelled peripherally inserted central catheter

2021 ◽  
pp. 112972982098737
Author(s):  
Teoh Sze Yong ◽  
Anushya A/P Vijayanathan ◽  
Eric Chung ◽  
Wei Lin Ng ◽  
Nur Adura Yaakup ◽  
...  
Keyword(s):  
Bloodstream Infection ◽  
Blood Stream Infection ◽  
Blood Stream ◽  
Peripherally Inserted Central Catheter ◽  
Central Catheter ◽  
Related Complication ◽  
Time Of Infection ◽  
The Mean ◽  
Mean Time ◽  
Crbsi Rate

Objective: To compare catheter related blood stream infection (CRBSI) rate between cuffed tunnelled and non-cuffed tunnelled PICC. Methods: We prospectively followed 100 patients (50:50 cuffed and non-cuffed PICC) and compared CRBSI rate between these groups. Daily review and similar catheter care were performed until a PICC-related complication, completion of therapy, death or defined end-of-study date necessitate removal. CRBSI was confirmed in each case by demonstrating concordance between isolates colonizing the PICC at the time of infection and from peripheral blood cultures. Results: A total of 50 cuffed PICC were placed for 1864 catheter-days. Of these, 12 patients (24%) developed infection, for which 5 patients (10%) had a CRBSI for a rate of 2.7 per 1000 catheter-days. Another 50 tunnelled non-cuffed PICCs were placed for 2057 catheter-days. Of these, 7 patients (14%) developed infection, for which 3 patients (6%) had a CRBSI. for a rate of 1.5 per 1000 catheter-days. The mean time to development of infection is 24 days in cuffed and 19 days in non-cuffed groups. The mean duration of utilization was significantly longer in non-cuffed than in cuffed group (43 days in non-cuffed vs 37 days in cuffed group, p = 0.008). Conclusions: Cuffed PICC does not further reduce the rate of local or bloodstream infection. Tunnelled non-cuffed PICC is shown to be as effective if not better at reducing risk of CRBSI and providing longer catheter dwell time compared to cuffed PICC.

Blood sampling frequency as a proxy for comorbidity indices when identifying patient samples for review of reference intervals

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Simon Lykkeboe ◽  
Stine Linding Andersen ◽  
Claus Gyrup Nielsen ◽  
Peter Vestergaard ◽  
Peter Astrup Christensen
Keyword(s):  
Laboratory Data ◽  
Low Frequency ◽  
Reference Interval ◽  
Reference Intervals ◽  
Sampling Frequency ◽  
Blood Sampling ◽  
Test Results ◽  
Healthy Individuals ◽  
Simple Method ◽  
Blood Samples

Abstract Objectives Indirect data mining methods have been proposed for review of published reference intervals (RIs), but methods for identifying patients with a low likelihood of disease are needed. Many indirect methods extract test results on patients with a low frequency blood sampling history to identify putative healthy individuals. Although it is implied there has been no attempt to validate if patients with a low frequency blood sampling history are healthy and if test results from these patients are suitable for RI review. Methods Danish nationwide health registers were linked with a blood sample database, recording a population of 316,337 adults over a ten-year period. Comorbidity indexes were defined from registrations of hospital diagnoses and redeemed prescriptions of drugs. Test results from patients identified as having a low disease burden were used for review of RIs from the Nordic Reference Interval Project (NORIP). Results Blood sampling frequency correlated with comorbidity Indexes and the proportion of patients without disease conditions were enriched among patients with a low number of blood samples. RIs based on test results from patients with only 1–3 blood samples per decade were for many analytes identical compared to NORIP RIs. Some analytes showed expected incongruences and gave conclusive insights into how well RIs from a more than 10 years old multi-center study (NORIP) performed on current pre-analytical and analytical methods. Conclusions Blood sampling frequency enhance the selection of healthy individuals for reviewing reference intervals, providing a simple method solely based on laboratory data without the addition of clinical information.

First experience with peripherally inserted central catheter for head and neck chemotherapy

Toukeibu Gan ◽  
2012 ◽  
Vol 38 (1) ◽  
pp. 80-83
Author(s):  
Akira Shimizu ◽  
Koichi Kitamura ◽  
Eriko Sakurai ◽  
Takahito Kondo ◽  
Yohei Okayoshi ◽  
...  
Keyword(s):  
Head And Neck ◽  
Peripherally Inserted Central Catheter ◽  
Central Catheter

scholarly journals Ultrasound-guided insertion of peripherally inserted central catheter after anesthetic induction in children undergoing surgery for moyamoya disease - A case report -

2021 ◽  
Author(s):  
Sang-Hwan Ji ◽  
Sol Ji Yoo ◽  
Sung-Ae Cho ◽  
Young-Eun Jang ◽  
Eun-Hee Kim ◽  
...  
Keyword(s):  
Moyamoya Disease ◽  
Anesthetic Management ◽  
Central Venous Access ◽  
Blood Sampling ◽  
Peripherally Inserted Central Catheter ◽  
Central Catheter ◽  
Ultrasound Guided ◽  
Central Venous ◽  
Anesthetic Induction ◽  
Insertion Depth

Background: Pediatric patients with moyamoya disease are vulnerable to ischemic attacks following physical or emotional stress, such as those experienced during blood sampling. A central venous catheter might be beneficial for blood sampling, and a peripherally inserted central catheter (PICC) is a considerable option for central venous access. However, PICC insertion during anesthetic management is relatively rare.Case: Thirty cases of ultrasound-guided PICC insertion were performed in children undergoing surgery for moyamoya disease after anesthetic induction. Positioning was successful in 22 cases, and 5 were malpositioned. In three cases, the peripheral insertion failed. Adjustment of the insertion depth was performed in nine cases. No complications related to catheterization were observed during the procedure or the catheter indwelling period.Conclusions: We report the successful use of PICC in children undergoing surgery for moyamoya disease with a considerable success rate and low incidence of malpositioning or complications.

scholarly journals Effect of Early Removal of Central Catheterization in Febrile Neutropenic Patients with Acute Leukemia

Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 4895-4895
Author(s):  
Su Hyun Hwang ◽  
Yong Won Choi ◽  
Seong Hyun Jeong ◽  
Joon Seong Park
Keyword(s):  
Febrile Neutropenia ◽  
Acute Leukemia ◽  
Conflicts Of Interest ◽  
Blood Stream Infection ◽  
Univariate Analysis ◽  
Blood Stream ◽  
Central Line ◽  
Central Catheter ◽  
Early Removal ◽  
Neutropenic Patients

Abstract Background: A guideline of central line-related blood stream infection (CRBSI) is only for immune-competent patients with end-stage renal disease on hemodialysis. We need widely acceptable guideline whether remove or maintain a central catheter in febrile neutropenic patients. Method: Medical records from 293 cases (95 patients) of febrile neutropenia with Central Catheterization were obtained retrospectively, and clinical characteristics, particularly duration of fever, were analyzed according to the early removal of central catheterization under anti-cancer chemotherapy for acute leukemia. Results: Forty-eight cases (16.4%) have already baseline fever and 25 cases (8.5%) showed baseline pneumonic infiltration prior to chemotherapy. The insertion sites of catheterization were subclavian (85.3%), internal jugular (12.6%), and others (2.0%). Early removal of central catheter was done at 93 cases (31.7%) and the cause of early removal was fever (63.4%), malfunction (11.8%), and others (24.7%). The duration of fever was significantly shortened by early removal of central catheterization (5.4 vs 7.5 days, p=0.003, Figure 1A). In addition, the duration of fever was related with age, diagnosis, type of chemotherapy, presence of baseline fever or pneumonic consolidation in univariate analysis. The site of central access or body mass index as well as existence of CRBSI did not affect duration of fever. In multivariate analysis, early removal of central catheter was independently associated with short duration of fever (OR=0.619, 95% CI=0.46-0.83, p=0.001, Table 1). The effect of early removal of central catheter was highlighted when micro-organisms were documented (Figure 1B). Summary: In patients with febrile neutropenia, early removal of central catheter can shorten the duration of fever particularly when BSI was documented. Disclosures No relevant conflicts of interest to declare.

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