Recent Advances in Bioinformatics in the Medical Research Environment and Applications to the Study of Skin Diseases

2000 ◽  
Vol 4 (3) ◽  
pp. 168-172
Author(s):  
A. Jamie Cuticchia

Background: The computer has become increasingly intertwined in society for the past 30 years. Within the academic health science centre, there is an increasing need for researchers to become skilled at using the Internet as a mechanism for the retrieval of scientific results and the underlying data. The discipline of bioinformatics, which uses computer technology to provide answers to biological questions, has been expanding in scope and utility for the past decade. Increasing numbers of research groups have been investing in bioinformatics infrastructure to aid in the research process. These continuing investments have led to the establishment for the first time of a supercomputing facility within a hospital. Such computational power is being used for the mapping of genes and the study of human disease. Objective: A discussion of the increasing role of computational biology in the research environment of the clinician scientist is presented here. Conclusions: Though the investment in a supercomputer may not be possible in most research settings, several less expensive alternatives relying on existing desktop computers can provide supercomputer-like performance within nearly any environment.

An essential text for accounting and finance students undertaking research for the first time. It demystifies the research process by providing the novice researcher with a must-have guide through all of the stages of the research process, from identifying a research topic to the finished project.


Author(s):  
Michael D. Franzen ◽  
Matthew J. L. Page

There has been an explosion in the development of electronic methods for psychological assessment. These include use of handheld devices, desktop computers, and platform-based Internet methods. This development has occurred separately in the commercial environment and in the research environment. This development of new methods presents great promise to improve the accuracy, ecological validity, and range of constructs in psychological assessment. However there are also many problems involved in the development of these electronic methods, including the need to train clinicians in their use, the need to develop safeguards for privacy, and the need to develop methods to ensure the integrity of the data collected. This chapter outlines some of the main considerations in moving forward.


2012 ◽  
Vol 1 (2) ◽  
pp. 282-300 ◽  
Author(s):  
Cécile Mathou ◽  
Jin Yan

Abstract The objective of this study was to provide comprehensive information about student and academic staff mobility between the European Union (EU) and China as well as the main strategies and policies in place to promote mobility. Based on quantitative and qualitative data provided by national authorities and various stakeholders consulted throughout the research process, the study aimed at taking stock of the situation and identifying trends regarding EU-China learning mobility over the past ten years. It also aimed at drawing recommendations to improve current and future mobility actions between the two regions.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1893-1893
Author(s):  
I. Manor ◽  
G. Yazpan

ADHD is a well-known, chronic disorder that persists in adulthood. During the past 20 years its existence in adults is becoming clearer, yet its dynamic aspects are rarely discussed. The treatment of adults is vital, as much as that of children; however the literature discussing it, especially its non-pharmacological aspect, is scarce.We describe the results of our treatment with drama-therapy of two groups of adults with ADHD. These groups included 11 adults (from both groups), men and women, from most socioeconomic strata, aged ≥ 60 yrs., who were diagnosed as suffering from ADHD and were treated for it for the first time in their life. Drama-therapy was selected as we believed it to be a useful method with associative, distracted ADHD patients, since it enabled the use of transitional space through non-verbal images and acts.This presentation discusses the basic themes with which patients began therapy. Interestingly, all patients, however different, shared the same themes that were built on self doubt and the pre-presumption of disappointment. The impairment related to ADHD, that was felt, but not understood, led to a strong experience of heavy losses, which we tried to define separately: of a clear path, of control, of the inner perception of borders and of the loss of an integrative inner self. All these losses were accumulated in the transitional space in a place we named “Nowhere land”.We would like to present these themes of losses and of becoming lost and to discuss their meaning.


Exchange ◽  
1982 ◽  
Vol 11 (1) ◽  
pp. 48-57

AbstractMons. Antonio Batista Fragoso has been bishop of Crateus in Northeast Brazil for the past ten years. Eighty percent of the 360,000 people in his diocese are impoverished peasants who engage in rudimentary farming. At least half of the peasants are landless. It is among these people that Bishop Fragoso has encouraged the formation of small grassroots Christian communities that are responsible for a profound change in the patterns of Christian living in his diocese. The following is LP's translation of excerpts from a talk that Bishop Fragoso gave to his fellow bishops and priests in Managua in October, 1980. This is the first time it has appeared in English. (Editor Latinamerica Press)


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Simon Reich ◽  
Dajie Zhang ◽  
Tomas Kulvicius ◽  
Sven Bölte ◽  
Karin Nielsen-Saines ◽  
...  

AbstractThe past decade has evinced a boom of computer-based approaches to aid movement assessment in early infancy. Increasing interests have been dedicated to develop AI driven approaches to complement the classic Prechtl general movements assessment (GMA). This study proposes a novel machine learning algorithm to detect an age-specific movement pattern, the fidgety movements (FMs), in a prospectively collected sample of typically developing infants. Participants were recorded using a passive, single camera RGB video stream. The dataset of 2800 five-second snippets was annotated by two well-trained and experienced GMA assessors, with excellent inter- and intra-rater reliabilities. Using OpenPose, the infant full pose was recovered from the video stream in the form of a 25-points skeleton. This skeleton was used as input vector for a shallow multilayer neural network (SMNN). An ablation study was performed to justify the network’s architecture and hyperparameters. We show for the first time that the SMNN is sufficient to discriminate fidgety from non-fidgety movements in a sample of age-specific typical movements with a classification accuracy of 88%. The computer-based solutions will complement original GMA to consistently perform accurate and efficient screening and diagnosis that may become universally accessible in daily clinical practice in the future.


Zootaxa ◽  
2021 ◽  
Vol 4996 (3) ◽  
pp. 492-512
Author(s):  
PAN-WEN HSUEH

Two new species and one new record species of the genus Pseudonereis are described from specimens collected from ecological surveys of coasts of Taiwan and an offshore island during the past 15 years: P. jihueiensis n. sp., P. kihawensis n. sp., and P. trimaculata. Epitokes of P. jihueiensis n. sp. and P. trimaculata are also described. Pseudonereis jihueiensis n. sp. can be distinguished from congeners by having edentate jaws, χ-shaped ridge pattern of Areas VI–V–VI, parapodial morphology (i.e., length ratio of dorsal cirrus to dorsal ligule or presence of small pennant-like dorsal ligule, shape of dorsal ligule in certain region of chaetigers), and no heterogomph spinigers in the subacicular fascicle of the neuropodia. Pseudonereis kihawensis n. sp. differs from congeners by having crescent-shaped pointed-bars in Area VI, λ-shaped ridge pattern of Areas VI–V–VI, parapodial morphology (i.e., length ratio of dorsal cirrus to dorsal ligule or presence of small pennant-like dorsal ligule or shape of dorsal ligule in certain region of chaetigers), and no heterogomph spinigers in the subacicular fascicle of the neuropodia. Pseudonereis trimaculata, a species originally described from Indonesia, is reported from Taiwan for the first time. A table of key characters for all species of Pseudonereis is provided.  


Belleten ◽  
2012 ◽  
Vol 76 (276) ◽  
pp. 385-402
Author(s):  
Murat Kılıç

The origins of the imperial cult in Smyrna date back to the Hellenistic period. It is a fact that political concerns were effective in the generation of such cults. Predicting the super power of the future and proving to be a loyal ally whilst acting in satisfactory behaviors were essential factors. The right preference made between two fighting or contending powers ensured that a city would benefit from various privileges in the future. For example, Symrna, which had established a cult in the city previously on behalf of Stratonice, the mother of Antiochus II of Seleucid dynasty, would do the same by building a temple in the name of the dty of Rome for the first time in Asia in 195 BC, after recognizing the rising power. Later on, while giving permission to the provinces that wanted to establish an imperial cult, the Roman emperors and the Senate would consider first, their relationships with Rome in the past and second, their origins. Smyrna, building its relationships with the Roman state on a solid basis, was granted the title of neokoros three times by the Roman Emperors Tiberius, Hadrianus and Caracalla, respectively. In this essay, the development of the Roman imperial cult in Smyrna is discussed within the historical process outlined above. An attempt has been made to put forth new opinions about the issue by discussing the academicians' evaluations on the imperial cult, which apparently was effectively executed in Smyrna between the first and third centuries AD, with the support of epigraphic and numismatic evidences.


2018 ◽  
Vol 19 (5) ◽  
pp. 339-359
Author(s):  
Richard W. Hill ◽  
Daniel Coleman

This co-authored article examines the oldest known treaty between incoming Europeans and Indigenous North Americans to derive five basic principles to guide healthy, productive relationships between Indigenous community-based researchers and university-based ones. Rick Hill, Tuscarora artist and knowledge keeper from the Six Nations of the Grand River, publishes for the first time here the most complete oral history that exists today of that ancient treaty, from the early seventeenth century, known as the Two Row Wampum or the Covenant Chain agreement. Interspersed with Dr. Hill’s reflections, Daniel Coleman, a settler professor of English and Cultural Studies at McMaster University, outlines five principles for research partnerships derived from the discussions of the Two Row Research Partnership seminars that Hill and Coleman have been hosting at Deyohahá:ge: Indigenous Knowledge Centre for the past four years. Formed between the Hodinöhsö:ni’ confederacy and Dutch merchants arriving near Albany, New York in 1609, the Two Row Wampum-Covenant Chain treaty set the precedent for nation-to-nation treaties between European colonial powers and Indigenous peoples with two parallel rows representing the Hodinöhsö:ni’ canoe and the Dutch ship sailing down the shared river. Each party agreed to keep their beliefs and laws in their separate vessels, and on this basis of interdependent autonomy, they established a long-lasting friendship. This article suggests that by renewing our understanding of the Two Row Wampum-Covenant Chain treaty, Indigenous and non-Indigenous researchers alike can rebuild relationships of trust and cooperation that can decolonize Western presumptions and re-establish healthy and productive research partnerships.


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