Bone health and multiple sclerosis

2012 ◽  
Vol 18 (11) ◽  
pp. 1522-1528 ◽  
Author(s):  
Ruth Dobson ◽  
Sreeram Ramagopalan ◽  
Gavin Giovannoni
Keyword(s):  
Multiple Sclerosis ◽  
Bone Mineral Density ◽  
Clinical Practice ◽  
General Population ◽  
Fracture Risk ◽  
Bone Mineral ◽  
Bone Health ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
The Relationship

People with multiple sclerosis (MS) have many reasons to have low bone mineral density and an increased fracture risk. Osteoporosis is a major cause of morbidity and mortality, and is more common in people with MS than the general population. A number of studies have examined the relationship between multiple sclerosis and reduced bone mineral density. In this topical review we seek to address the risk of low bone mineral density, osteoporosis and fractures associated with MS, and make practical suggestions as to how this pertinent issue may be approached in clinical practice.

scholarly journals Poor Vitamin K Status Is Associated With Low Bone Mineral Density and Increased Fracture Risk in End-Stage Renal Disease

2018 ◽  
Vol 34 (2) ◽  
pp. 262-269 ◽  
Author(s):  
Pieter Evenepoel ◽  
Kathleen Claes ◽  
Bjorn Meijers ◽  
Michaël Laurent ◽  
Bert Bammens ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Renal Disease ◽  
Fracture Risk ◽  
Bone Mineral ◽  
Vitamin K ◽  
End Stage Renal Disease ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Association of bone mineral density with lung function in a Chinese general population: the Xinxiang rural cohort study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Xiang Zeng ◽  
Dongling Liu ◽  
Xiangmei Zhao ◽  
Ling Chao ◽  
Yuchun Li ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Lung Function ◽  
General Population ◽  
Bone Mineral ◽  
Chronic Obstructive ◽  
Reference Area ◽  
Mineral Density ◽  
Obstructive Pulmonary Disease ◽  
Lower Lung ◽  
The Relationship

Abstract Background Bone mineral density (BMD) has been positively associated with lung function in patients diagnosed with respiratory diseases such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis. However, the relationship between BMD and lung function is inconsistent in the general population. Methods To investigate the association between BMD and lung function in a Chinese general population, a total of 1024 adults aged 40–70 years old from Qiliying (an industrial polluted exposure area) and Langgongmiao (the reference area with non-industrial pollution) were recruited and underwent BMD and spirometry tests. Results Both BMD and lung function levels were lower in the exposed area compared to the reference area. In addition, BMD and lung function levels were also lower in females compared to males. Both Spearman and partial correlation analyses showed that BMD was positively correlated with FVC and FEV1. After adjusting linear regression analyses for potential confounding factors, every 0.1 g/cm2 drop in BMD was associated with 53.0 mL decrease in FVC and 33.5 mL decrease in FEV1. Conclusions A reduction of BMD is associated with lower lung function in a general population from China.

scholarly journals Low Bone Mineral Density, Renal Dysfunction, and Fracture Risk in HIV Infection: A Cross‐Sectional Study

2009 ◽  
Vol 200 (11) ◽  
pp. 1746-1754 ◽  
Author(s):  
Alexandra Calmy ◽  
Christoph A. Fux ◽  
Richard Norris ◽  
Nathalie Vallier ◽  
Cécile Delhumeau ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Hiv Infection ◽  
Fracture Risk ◽  
Renal Dysfunction ◽  
Bone Mineral ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional ◽  
Low Bone Mineral Density

scholarly journals Bone mineral density, polyphenols and caffeine: a reassessment

2007 ◽  
Vol 20 (1) ◽  
pp. 89-105 ◽  
Author(s):  
T. P. Dew ◽  
A. J. Day ◽  
M. R. A. Morgan
Keyword(s):  
Bone Mineral Density ◽  
Fracture Risk ◽  
Bone Mineral ◽  
Bone Health ◽  
Fruit And Vegetables ◽  
Fruit And Vegetable ◽  
Mineral Density ◽  
Caffeine Consumption ◽  
Positive Effects

Several studies have shown beneficial associations between tea consumption and bone mineral density (BMD) and fracture risk. Current investigations into potential mechanisms of benefit are focused upon the F and polyphenol components of tea. However, previous studies have pointed towards caffeine consumption as a potential risk factor for low BMD and high fracture risk. Tea, therefore, represents an interesting paradox as a mildly caffeinated beverage that may enhance bone health. Fruit and vegetable intake has also been associated with BMD, and it is now apparent that several fruit and vegetable components, including polyphenols, may contribute positively to bone health. Evidence surrounding the function(s) of polyphenol-rich foods in bone health is examined, along with more recent studies challenging the relevance of caffeine consumption to in vivo Ca balance. Plant foods rich in polyphenols such as tea, fruit and vegetables, as significant factors in a healthy diet and lifestyle, may have positive roles in bone health, and the negative role of caffeine may have been overestimated. The present review covers evidence of dietary mediation in positive and negative aspects of bone health, in particular the roles of tea, fruit and vegetables, and of caffeine, flavonoids and polyphenols as components of these foods. Since the deleterious effects of caffeine appear to have been overstated, especially in respect of the positive effects of flavonoids, it is concluded that a reassessment of the role of caffeinated beverages may be necessary.

scholarly journals The Relationship between Nutrient Patterns and Bone Mineral Density in Postmenopausal Women

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1262 ◽  
Author(s):  
Bolaji Lilian Ilesanmi-Oyelere ◽  
Louise Brough ◽  
Jane Coad ◽  
Nicole Roy ◽  
Marlena Cathorina Kruger
Keyword(s):  
Bone Mineral Density ◽  
Fatty Acids ◽  
Vitamin E ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Bone Health ◽  
Mineral Density ◽  
Omega 6 ◽  
Nutrient Patterns ◽  
The Relationship

In women, the menopausal transition is characterized by acid-base imbalance, estrogen deficiency and rapid bone loss. Research into nutritional factors that influence bone health is therefore necessary. In this study, the relationship between nutrient patterns and nutrients important for bone health with bone mineral density (BMD) was explored. In this cross-sectional analysis, 101 participants aged between 54 and 81 years were eligible. Body composition and BMD analyses were performed using dual-energy X-ray absorptiometry (DXA). Nutrient data were extracted from a 3-day diet diary (3-DDD) using Foodworks 9 and metabolic equivalent (MET-minutes) was calculated from a self-reported New Zealand physical activity questionnaire (NZPAQ). Significant positive correlations were found between intakes of calcium (p = 0.003, r = 0.294), protein (p = 0.013, r = 0.246), riboflavin (p = 0.020, r = 0.232), niacin equivalent (p = 0.010, r = 0.256) and spine BMD. A nutrient pattern high in riboflavin, phosphorus and calcium was significantly positively correlated with spine (p < 0.05, r = 0.197) and femoral neck BMD (p < 0.05, r = 0.213), while the nutrient pattern high in vitamin E, α-tocopherol, β-carotene and omega 6 fatty acids was negatively correlated with hip (p < 0.05, r = −0.215) and trochanter BMD (p < 0.05, r = −0.251). These findings support the hypothesis that a nutrient pattern high in the intake of vitamin E, α-tocopherol and omega 6 fatty acids appears to be detrimental for bone health in postmenopausal women.

scholarly journals Exploring the Relationships Among the Inflammatory Potential of the Diet, Bone Mineral Density, and Injury Incidence in Collegiate Athletes (P23-006-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Kiley Field ◽  
John Gieng ◽  
Giselle Pignotti ◽  
Sofia Apsey
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Bone Health ◽  
Collegiate Athletes ◽  
Whole Body ◽  
Research Centre ◽  
Injury Incidence ◽  
Mineral Density ◽  
The Relationship ◽  
Prior Injury

Abstract Objectives The relationship between the inflammatory potential of the diet, estimated by the Dietary Inflammatory Index (DII) score, and bone health has been studied in older populations and suggests that the diet can influence bone mineral density (BMD) and fracture risk. These relationships have yet to be explored in other potentially vulnerable populations, such as athletes, where risk of injuries may be more common due to high physical stresses and over-use. The aims of this study were 1) to examine the correlation between DII scores, and BMD in collegiate athletes, and 2) to assess the relationship between DII score and self-reported prior injury incidence. Methods Healthy collegiate athletes (n = 43) were recruited for this study: football, n = 12; men's soccer, n = 2; women's soccer, n = 13; women's swimming, n = 12; and women's basketball, n = 4. For each athlete, three 24-hour dietary intakes were collected using a standardized multiple-pass interview methodology (Nutrition Data System for Research) and this data was used to calculate individual DII scores. Body composition, including whole-body sub-total BMD, was measured using dual-energy X-ray absorptiometry. A modified overuse injury questionnaire (Oslo Sports Trauma Research Centre) was used to assess incidence of injuries in the prior 12 months. Results The participants (n = 14 male, n = 29 female) had a mean age of 19.4 ± 1.1 yrs and BMI of 25.8 ± 4.1 kg/m2. Mean DII score was −0.43 ± 0.17 points (range: −3.94 to 4.34). Mean BMD was 1.251 ± 0.169 g/cm2. Overall, DII score and BMD was not correlated (P = 0.47). Furthermore, DII scores of athletes that reported no prior injury did not differ from those who reported 1 or more injuries. Conclusions Unlike research in postmenopausal women, it appears that bone health of young healthy athletes is less vulnerable to the influence of diets with higher inflammatory potential. Moreover, the lack of difference in DII score among athletes reporting various levels of prior injury suggests that the inflammatory potential of the diet is a poor predictor of injury risk in collegiate athletes. Funding Sources N/A.

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