scholarly journals Effects of Cystatin C on Cognitive Impairment in Older Chinese Adults

2020 ◽  
Vol 35 ◽  
pp. 153331752096510
Author(s):  
Zhizhen Cui ◽  
Guizhen Cao ◽  
Youyi Wang ◽  
Qinghua Ma ◽  
Congju Wang ◽  
...  

Objective: To find a suitable dividing value to classify cystatin C and evaluate the association between cognition and levels of cystatin C. Methods: Using data from the China Health and Retirement Longitudinal Study, We conducted a longitudinal analysis of a prospective cohort of 6,869 middle-aged and older Chinese without cognitive impairment at baseline. Levels of cystatin C were categorized into 2 groups by method of decision tree. Logistic regression models evaluated whether cystatin C was related to cognitive impairment. Results: Respondents were categorized as lower levels of cystatin C and higher levels of cystatin C, cut-point was 1.11 mg/L. Higher levels of cystatin C was associated with the odds of cognitive impairment (OR, 1.56; 95% CI, 1.10-2.22) after multivariable adjustment. Respondents with higher levels of cystatin C had worse cognition scores. Conclusions: We found a suitable dividing value of cystatin C in middle-aged and older Chinese.

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Md Mizanur Rahman ◽  
Chang Yong Liang ◽  
Dongxiao Gu ◽  
Yong Ding ◽  
Monira Akter

Objective. Middle-aged and older Chinese adults (35 to 75) failed to meet the recommendations of physical activity guidelines for health promotion, because of a lack of understanding of their perspective on physical activity. This study considers the physical activity levels and motivation among middle-aged and older Chinese adults partitioned into three different participation groups (sports, exercise, and recreational and cultural activities). Methods. A cross-sectional analysis was performed on 633 participants, based on two different levels of physical activity levels. The International Physical Activity Questionnaire (IPAQ) and the Exercise Motivation Inventory (EMI-2) with 14 subscales were used to measure the participant’s physical activity levels and physical activity motivation for the three different group activities. Results. Results indicate those participants’ physical activity levels and motivation varied significantly among the different groups. The participants who engage in recreational and cultural activities have a higher motivation for physical activity, as compared with those whose primary form of physical activity is sports and exercise, and a higher probability to fulfill the global recommendations concerning physical activity. Participants who used recreational and cultural activities as their major type of physical activities were more motivated by “intrinsic” aspects. In contrast, those who participate in sports and exercise as their main type of physical activity are more motivated by “extrinsic” aspects. Conclusion. Close friends and family members of one’s home and community have potential influence in physical activity and recreational and cultural activity participants are highly motivated and luckier than others to fulfill the goal of physical activity levels.


2018 ◽  
Vol 41 (3) ◽  
pp. 518-526 ◽  
Author(s):  
Jiaan Zhang ◽  
Sara J McLaughlin ◽  
Lydia W Li

Abstract Background Research on the health effects of exposure to air pollution is growing. However, relatively little attention has been paid to the effects of long-term and cumulative exposure to air pollutants. Individual-level studies on the health consequences of air pollution in China are especially scarce. The purpose of this study is to examine the effect of cumulative exposure to sulfur dioxide (SO2), an air pollutant of particular concern in China, on all-cause mortality in older Chinese adults. Methods Using a nationally representative sample of older adults in China (N = 11 199), we tracked mortality over an 11-year period (2000–11). Air pollution data were linked to respondents using provincial identifiers. To examine the effect of cumulative SO2 exposure on mortality, we employed multilevel multinomial logistic regression models that account for within subject clustering of observations over time and clustering at the province level. Results We found that every 10-μg/m3 increase in cumulative exposure to SO2 increased the odds of death by nearly 1% (OR = 1.008; 95% CI: 1.002–1.014), controlling for province- and individual-level social and economic characteristics. Conclusions Our analysis shows that air pollution is a risk factor for morality in older Chinese adults. Findings suggest that stronger SO2 regulations may enhance longevity.


Author(s):  
Jialin Fu ◽  
Xinge Zhang ◽  
Justin B. Moore ◽  
Bowen Wang ◽  
Rui Li

The goal of this study was to investigate the associations of midday nap duration and change in midday nap duration with hypertension in a retrospective cohort using a nationwide representative sample of middle-aged and older Chinese adults. Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS) database during 2011–2015. Information on midday nap duration was collected via a self-reported questionnaire and blood pressure was objectively measured. Hazard ratios (HR) with 95% confidence interval (CI) were estimated using Cox proportional hazards regression models to quantify the associations. A sample of 5729 Chinese adults (≥45 years old) were included in the longitudinal analysis. Relative to non-nappers, participants who napping for ≥90 min/day was associated with significantly larger HR for hypertension at four-year follow-up (HR = 1.18, 95% CI = 1.01–1.40, p = 0.048). Compared with people who napped ≥90 min/day both at baseline (2011) and follow-up (2013), hypertension risk at four-year follow-up declined in individuals whose midday nap durations decreased in the 2-year study period from ≥ 90 min/day to 1–59 min/day (HR = 0.59, 95% CI = 0.36–0.97, p = 0.037) and 60–89 min/day (HR = 0.68, 95% CI = 0.47–0.99, p = 0.044). Among middle-aged and older Chinese adults, relative to non-nappers, people who had longer midday nap duration (≥90 min/day) were associated with significantly larger HR for hypertension and decreased napping duration may confer benefit for hypertension prevention.


2008 ◽  
Vol 88 (1) ◽  
pp. 224-231 ◽  
Author(s):  
Tze-Pin Ng ◽  
Lei Feng ◽  
Mathew Niti ◽  
Ee-Heok Kua ◽  
Keng-Bee Yap

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