Compact 3D-Printed Active Flexible Needle for Percutaneous Procedures

2020 ◽  
pp. 155335062094556
Author(s):  
Zahra K. Varnamkhasti ◽  
Bardia Konh
Keyword(s):  
Medical Imaging ◽  
Clinical Outcomes ◽  
Control Unit ◽  
Prostate Brachytherapy ◽  
Needle Placement ◽  
Percutaneous Procedures ◽  
Tissue Phantom ◽  
Tumor Visualization ◽  
Angular Deflection ◽  
3D Printed

Needle-based intervention has been a popular procedure for diagnosis and treatment of many types of cancer. However, poor needle placement and tumor visualization have been among the challenges resulting in poor clinical outcomes. There has been a lot of progress in medical imaging technology, but the structure of surgical needles has remained unchanged. This work presents a wire-driven 3D steerable, 3D-printed active needle for improved guidance inside the tissue toward the target. The needle is manipulated by 3 embedded tendons via a programmed motorized control unit. Feasibility tests in a tissue phantom showed an average 3D needle angular deflection of about 11°. This amount of angular deflection is expected to assist prostate brachytherapy via a curvilinear approach.

Design, Fabrication, and Testing of a Flexible Three-Dimensional Printed Percutaneous Needle with Embedded Actuators

2020 ◽  
Author(s):  
Zahra Khashei Varnamkhasti ◽  
Bardia Konh
Keyword(s):  
Breast Biopsy ◽  
Three Dimensional ◽  
Control Unit ◽  
Prostate Brachytherapy ◽  
Cancer Treatments ◽  
Tissue Samples ◽  
Minimal Invasiveness ◽  
Tissue Phantom ◽  
Angular Deflection ◽  
3D Printed

Abstract Percutaneous needle procedures have replaced open surgeries in cancer treatments to perform the tasks with minimal invasiveness to the tissue. Precise placement of the needle at target positions in cancer diagnostic (e.g., breast biopsy) or therapeutic (e.g., prostate brachytherapy) procedures governs the success of such procedures. Also, in many applications it is desired to steer the needle away from critical organs or anatomical obstacles towards the target. This work introduces a three-dimensional (3D) printed surgical needle with embedded actuators for improved flexibility and manipulation inside the tissue towards the target. The needle is manipulated via a programmed portable motorized control unit. Performance evaluation experiments in air and in a tissue phantom showed an average angular deflection of 11 degrees towards each actuator. The needle's capability to reach the target, avoiding obstacles has also been shown. The controllable 3D deflection of the needle is expected to assist in breast cancer lumpectomy for multiple extractions of tissue samples or in prostate brachytherapy via a curvilinear approach. The needle can be eventually used in trajectory tracking and to improve targeting accuracy.

scholarly journals Optical fibre based real-time measurements during an LDR prostate brachytherapy implant simulation: using a 3D printed anthropomorphic phantom

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
P. Woulfe ◽  
F. J. Sullivan ◽  
L. Byrne ◽  
A. J. Doyle ◽  
W. Kam ◽  
...  
Keyword(s):  
Optical Fibre ◽  
Planning System ◽  
Treatment Planning System ◽  
Prostate Brachytherapy ◽  
Anthropomorphic Phantom ◽  
Optical Fibre Sensor ◽  
Ldr Brachytherapy ◽  
3D Printed ◽  
Average Activity ◽  
Iodine 125

AbstractAn optical fibre sensor based on radioluminescence, using the scintillation material terbium doped gadolinium oxysulphide (Gd2O2S:Tb) is evaluated, using a 3D printed anthropomorphic phantom for applications in low dose-rate (LDR) prostate brachytherapy. The scintillation material is embedded in a 700 µm diameter cavity within a 1 mm plastic optical fibre that is fixed within a brachytherapy needle. The high spatial resolution dosimeter is used to measure the dose contribution from Iodine-125 (I-125) seeds. Initially, the effects of sterilisation on the sensors (1) repeatability, (2) response as a function of angle, and (3) response as a function of distance, are evaluated in a custom polymethyl methacrylate phantom. Results obtained in this study demonstrate that the output response of the sensor, pre- and post-sterilisation are within the acceptable measurement uncertainty ranging from a maximum standard deviation of 4.7% pre and 5.5% post respectively, indicating that the low temperature sterilisation process does not damage the sensor or reduce performance. Subsequently, an LDR brachytherapy plan reconstructed using the VariSeed treatment planning system, in an anthropomorphic 3D printed training phantom, was used to assess the suitability of the sensor for applications in LDR brachytherapy. This phantom was printed based on patient anatomy, with the volume and dimensions of the prostate designed to represent that of the patient. I-125 brachytherapy seeds, with an average activity of 0.410 mCi, were implanted into the prostate phantom under trans-rectal ultrasound guidance; following the same techniques as employed in clinical practice by an experienced radiation oncologist. This work has demonstrated that this sensor is capable of accurately identifying when radioactive I-125 sources are introduced into the prostate via a brachytherapy needle.

Development and Validation of a Three-Dimensional Printed Training Model to Teach Ultrasound-Guided Injections of the Cervical Articular Process Joints in Horses

2021 ◽  
pp. e20200137
Author(s):  
Alexandra Beaulieu ◽  
Stephanie Nykamp ◽  
John Phillips ◽  
Luis G. Arroyo ◽  
Judith Koenig ◽  
...  
Keyword(s):  
Construct Validity ◽  
Content Validity ◽  
Three Dimensional ◽  
Joint Space ◽  
Needle Placement ◽  
Ultrasound Guided ◽  
Training Tool ◽  
Articular Process ◽  
The Face ◽  
3D Printed

Intra-articular injections are routinely performed to alleviate pain and inflammation associated with osteoarthritis in horses. Intra-articular injections require accurate needle placement to optimize clinical outcomes and minimize complications. This study’s objectives were to develop and validate a three-dimensional (3D) printed model of an equine cervical articular process joint to teach ultrasound-guided injections. Five identical models of an equine cervical articular process joint were 3D printed and embedded in 10% ballistic gelatin. Experts’ and novices’ ability to successfully insert a needle into the joint space of the model using ultrasound guidance was assessed and graded using an objective structured clinical examination (OSCE). Scores from experts and novices were compared to evaluate the construct validity of the model. Participants also answered a survey assessing the face and content validity of the model. Experts required less time (22.51 seconds) for correct needle placement into the model joint space than novices (35.96 seconds); however, this difference was not significant ( p = .53). Experts’ median total OSCE score (14) was significantly higher ( p = .03) than novices’ (12), supporting the model’s construct validity. Participants agreed on the face and content validity of the model by grading all survey questions greater than 7 on a 10-point Likert-type scale. In summary, we successfully developed a 3D printed model of an equine cervical articular process joint, partially demonstrated the construct validity of the model, and proved the face and content validity of this new training tool.

scholarly journals 3D Printed Acetabular Cups for Total Hip Arthroplasty: A Review Article

Metals ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 729 ◽  
Author(s):  
Dall’Ava ◽  
Hothi ◽  
Di Laura ◽  
Henckel ◽  
Hart
Keyword(s):  
3D Printing ◽  
Total Hip Arthroplasty ◽  
Clinical Outcomes ◽  
Hip Arthroplasty ◽  
Three Dimensional ◽  
Total Hip ◽  
3D Printed ◽  
Key Variables ◽  
End Use ◽  
Acetabular Components

Three-dimensional (3D) printed titanium orthopaedic implants have recently revolutionized the treatment of massive bone defects in the pelvis, and we are on the verge of a change from conventional to 3D printed manufacture for the mass production of millions of off-the-shelf (non-personalized) implants. The process of 3D printing has many adjustable variables, which taken together with the possible variation in designs that can be printed, has created even more possible variables in the final product that must be understood if we are to predict the performance and safety of 3D printed implants. We critically reviewed the clinical use of 3D printing in orthopaedics, focusing on cementless acetabular components used in total hip arthroplasty. We defined the clinical and engineering rationale of 3D printed acetabular cups, summarized the key variables involved in the manufacturing process that influence the properties of the final parts, together with the main limitations of this technology, and created a classification according to end-use application to help explain the controversial and topical issues. Whilst early clinical outcomes related to 3D printed cups have been promising, in-depth robust investigations are needed, partly because regulatory approval systems have not fully adapted to the change in technology. Analysis of both pristine and retrieved cups, together with long-term clinical outcomes, will help the transition to 3D printing to be managed safely.

An Examination of Clinical Outcomes in Patients Experiencing Biochemical Relapse in a Cohort of 966 Permanent Prostate Brachytherapy Monotherapy Patients

Brachytherapy ◽  
2016 ◽  
Vol 15 ◽  
pp. S176-S177
Author(s):  
Ryan Funk ◽  
Lance Mynderse ◽  
Wilson Torrence ◽  
Christopher Deufel ◽  
Keith Furutani ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Prostate Brachytherapy ◽  
Biochemical Relapse

scholarly journals From medical imaging data to 3D printed anatomical models

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0178540 ◽  
Author(s):  
Thore M. Bücking ◽  
Emma R. Hill ◽  
James L. Robertson ◽  
Efthymios Maneas ◽  
Andrew A. Plumb ◽  
...  
Keyword(s):  
Medical Imaging ◽  
Imaging Data ◽  
Anatomical Models ◽  
3D Printed ◽  
Medical Imaging Data
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