scholarly journals Medical evaluation and pharmacotherapeutical strategies in management of urolithiasis

2021 ◽  
Vol 13 ◽  
pp. 175628722199330
Author(s):  
Derry Minyao Ng ◽  
Maria Haleem ◽  
Anny Mamuchashvili ◽  
Kai-yun Wang ◽  
Jin-Feng Pan ◽  
...  
Keyword(s):  
Surgical Management ◽  
Treatment Plan ◽  
Size Composition ◽  
Patient Specific ◽  
Medical Evaluation ◽  
Specific Factors ◽  
Potential Damage ◽  
Treatment Of Urolithiasis ◽  
Made In

Treatment of urolithiasis depends on several important factors which include stone location, size, composition, and patient symptoms. Although significant advancements have been made in the surgical management of urolithiasis in the last decade, pharmacotherapy which can prevent the formation of new stones and decrease the recurrence of urolithiasis has not experienced the same level of success. Currently, urolithiasis is regarded as a complicated syndrome that is determined by numerous factors, and any treatment plan for urolithiasis should be individualized while considering any potential damage arising from stone-forming factors. This review introduces the most popular methods currently used to evaluate urolithiasis and the pharmacotherapy of urolithiasis based on patient-specific factors.

scholarly journals A novel and dynamic prediction engine for practicing precision medicine to prevent chemotherapy-induced nausea and vomiting

2015 ◽  
Author(s):  
◽  
Abu Saleh Mohammad Mosa
Keyword(s):  
Social Life ◽  
Treatment Plan ◽  
Life Quality ◽  
The United States ◽  
Nausea And Vomiting ◽  
Patient Specific ◽  
Dynamic Prediction ◽  
Personal Experiences ◽  
Specific Factors ◽  
Chemotherapy Patients

Cancer remains the second major cause of death in the United States over the last decade. Chemotherapy is a core component of nearly every cancer treatment plan. Chemotherapy-Induced Nausea and Vomiting (CINV) are the two most dreadful and unpleasant side-effects of chemotherapy for cancer patients. The consequences of CINV include: (1) impaired life quality, (2) poor social life, (3) burden on economy due to loss of workdays, (4) increased healthcare cost, and (5) denial of chemotherapy due to unendurable CINV. There are three clinical guidelines (ASCO, NCCN, and MASCC/ESMO) for the management of CINV. Several patient-specific factors affect the risk of CINV. However, none of the guidelines consider those factors. Not all of patients have the similar emetic risk of CINV. Despite the improvements in CINV management, as many as two-thirds of chemotherapy patients still experience some degree of CINV. As a result, physicians use their personal experiences for CINV treatment, which leads to inconsistent managements of CINV. The overall objective of this study is to improve the prevention of CINV using precise, personalized and evidence-based antiemetic treatment before chemotherapy. Physicians receive feedback about CINV risks of patients from a CINV decision support system based on patient-specific factors. This objective was achieved by accomplishing clinical innovations through the discovery of combined relationships of various patient-specific factors for causing CINV, and informatics innovations through the development of a novel, precise and dynamic prediction engine for practicing precision and personalized medicine in CINV prevention. The approach presented in this dissertation can be applied to any other clinical predictions.

Lithium-related medication problems on nonpsychiatric inpatient medical units

2019 ◽  
Vol 76 (Supplement_4) ◽  
pp. S96-S101 ◽  
Author(s):  
Jennifer N Alastanos ◽  
Teresa G Potter ◽  
Ericka L Crouse
Keyword(s):  
Retrospective Study ◽  
Lithium Concentration ◽  
Primary Objective ◽  
Patient Specific ◽  
Single Center ◽  
Serum Lithium Concentration ◽  
Factors Associated ◽  
Specific Factors ◽  
Made In

Abstract Purpose Results of a study of medication-related problems (MRPs) associated with lithium use on nonpsychiatric inpatient medical units are reported. Methods In a single-center, retrospective study, the records of all patients hospitalized over a 21-month period who received lithium or had a documented serum lithium concentration during hospitalization were evaluated. The primary objective was to identify patient-specific factors associated with lithium MRPs on nonpsychiatric inpatient medical units. Secondary objectives included characterization of lithium MRPs. Identified MRP occurrences were further evaluated to determine if an intervention was necessary to resolve the MRP and whether or not an intervention was made. Results A total of 150 patients were included in the study sample. One or more lithium MRPs were identified in 85% of the patients, with a total of 255 lithium MRPs identified. None of the patient-specific factors analyzed were significantly associated with MRP occurrence. Of the 128 patients in whom a lithium MRP occurred, 92.2% (n = 118) were judged to be appropriate candidates for interventions as defined per the study definitions; among those 118 patients, such interventions were documented for only 40.7% (n = 48). Conclusion Lithium MRPs were found to have occurred frequently on nonpsychiatric inpatient medical units at 1 hospital. Laboratory test– related MRPs and drug–drug interactions were the most commonly identified types of MRPs. Interventions to address MRPs were not made in the majority of patients; however, interventions were more frequently made when psychiatry consultation was involved.

scholarly journals Multiple sclerosis

2019 ◽  
Vol 9 (6) ◽  
pp. 349-358 ◽  
Author(s):  
Shilpa Klocke ◽  
Nicole Hahn
Keyword(s):  
Multiple Sclerosis ◽  
Therapeutic Strategies ◽  
Patient Specific ◽  
Clinical Case Study ◽  
Disease Modifying Therapies ◽  
Multiple Sclerosis Disease ◽  
Specific Factors ◽  
Disease Modifying ◽  
Made In

Abstract Multiple sclerosis is a chronic, unpredictable, and disabling disease. Significant advances have been made in recent years supporting an earlier, more accurate, diagnosis and have led to more than 15 disease-modifying therapies approved by the Food and Drug Administration for relapsing forms of multiple sclerosis. Disease-modifying therapies are now being classified into categories based on level of efficacy. Strategies to use disease-modifying therapies earlier and in a more customizable manner are also emerging. A clinical case study will be used throughout this pearl to review the disease-modifying therapies and use patient-specific factors to develop and provide recommendations on therapeutic strategies for individuals with relapsing forms of multiple sclerosis.

The new in monitoring of provision of cancer care in the Russian Federation

2019 ◽  
Vol 2019 (4) ◽  
pp. 35-37
Author(s):  
Наталья Стадченко ◽  
Natal'ya Stadchenko
Keyword(s):  
Russian Federation ◽  
Treatment Guidelines ◽  
Malignant Tumors ◽  
Patient Specific ◽  
Insurance Fund ◽  
Medical Aid ◽  
Proven Case ◽  
The Russian Federation ◽  
Positive Results ◽  
Made In

The Federal Compulsory Medical Insurance Fund created the system of a monitoring of medical aid provided for the oncology patients, which allows realizing control over execution of the treatment guidelines on every stage. Changes been made in the governing documents, aimed at development of patient-specific records of provided medical aid at suspicion on the malignant tumors or in proven case of the malignant tumors. The article presents the data on control and expert activities demonstrating positive results of that work.

Understanding the Patterns of Deformity of Wrist Fractures Using Computer Analysis

2020 ◽  
Vol 16 (3) ◽  
pp. 194-200
Author(s):  
Shai Luria
Keyword(s):  
Computer Modeling ◽  
Computer Analysis ◽  
Computer Models ◽  
Fracture Morphology ◽  
Patient Specific ◽  
Surgical Approaches ◽  
Surgical Indications ◽  
Wrist Fractures ◽  
Novel Methods ◽  
Made In

Computer modeling of the wrist has followed other fields in the search for descriptive methods to understand the biomechanics of injury. Using patient-specific 3D computer models, we may better understand the biomechanics of wrist fractures in order to plan better care. We may better estimate fracture morphology and stability and evaluate surgical indications, design more adequate or effective surgical approaches and develop novel methods of therapy. The purpose of this review is to question the actual advances made in the understanding of wrist fractures using computer models.

Successful recanalization for acute ischemic stroke via the transbrachial approach

2014 ◽  
Vol 8 (2) ◽  
pp. 122-125 ◽  
Author(s):  
Masakazu Okawa ◽  
Satoshi Tateshima ◽  
David Liebeskind ◽  
Latisha K Ali ◽  
Michael L Thompson ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Patient Specific ◽  
Ischemic Stroke Patient ◽  
Transfemoral Approach ◽  
Acute Ischemic Stroke Patient ◽  
Transbrachial Approach ◽  
Stent Retrievers ◽  
Endovascular Approach ◽  
Specific Factors

The recent development of revascularization devices, including stent retrievers, has enabled increasingly higher revascularization rates for arterial occlusions in acute ischemic stroke. Patient-specific factors such as anatomy, however, may occasionally limit endovascular deployment of these new devices via the conventional transfemoral approach. We report three cases of acute ischemic stroke where a transbrachial endovascular approach to revascularization was used, resulting in successful recanalization. These examples suggest that a transbrachial approach may be considered as an alternative in the endovascular treatment of acute ischemic stroke.

Measurement of B-domain-deleted ReFacto AF activity with a product-specific standard is affected by choice of reagent and patient-specific factors

Haemophilia ◽  
2017 ◽  
Vol 24 (4) ◽  
pp. 675-682 ◽  
Author(s):  
M. Jacquemin ◽  
A. Vodolazkaia ◽  
J. Toelen ◽  
J. Schoeters ◽  
I. Van Horenbeeck ◽  
...  
Keyword(s):  
Patient Specific ◽  
Specific Standard ◽  
Specific Factors

Supportive care with art therapy, for patients in isolation during stem cell transplant

2012 ◽  
Vol 10 (2) ◽  
pp. 91-98 ◽  
Author(s):  
Alessandra Agnese ◽  
Teresa Lamparelli ◽  
Andrea Bacigalupo ◽  
Paola Luzzatto
Keyword(s):  
Stem Cell ◽  
Art Therapy ◽  
Stem Cell Transplant ◽  
Hemopoietic Stem Cell ◽  
Cell Transplant ◽  
Self Assessment ◽  
Specific Factors ◽  
Meaningful Connections ◽  
Art Therapist ◽  
Made In

AbstractObjective:The aim of the art therapy study was twofold: 1) to identify the specific factors of the art therapy experience perceived as helpful by patients undergoing an allogenic hemopoietic stem cell transplant (HSCT); and 2) to establish an appropriate criterion for referral to art therapy among this population.Method:Between 2006 and 2010, a dedicated art therapist met all the patients who were referred to her by the hematologist. The art therapy approach and techniques are described. Outcome was evaluated by self-assessment, based on written questionnaires that were given to the patients before discharge.Results:Seventy-four patients followed the weekly individual sessions during isolation and filled out the questionnaire. All of them defined the art therapy experience as “helpful” and specified in which way it had been helpful. Through a thematic analysis of the patients' written comments, three specific aspects of art therapy, which the patients found most helpful, were identified: (1) being able to calm down from anxiety, through the use of art therapy techniques (77.02%); (2) feeling free to express and share difficult feelings, which they had not communicated verbally (75.67%); and (3) establishing meaningful connections with their loved ones, through images made in art therapy (36.48%). Case illustrations are provided.Significance of results:The results suggest that referral to art therapy from the team might be helpful and appropriate: (1) when patients are anxious; (2) when they are uncommunicative and hide their feelings; and (3) when they feel disconnected from their loved ones at home.

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