The use of the Comins-Meyers Amide in Synthetic Chemistry: An Overview
2016 ◽
Vol 11
(11)
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pp. 1934578X1601101
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Formylation reactions are fundamental operations in synthetic chemistry allowing the incorporation into a given structure formyl groups amenable to further derivatization. Conceptually, the introduction of such groups through the reaction between an electrophilic donor and a nucleophilic acceptor ( i.e. organometallic reagent) constitutes a reliable technique with widespread applications. In this Highlight, we summarize the effectiveness of the so called Comins-Meyers amide - [2-( N-methyl- N-formylamino]pyridine – in such a chemistry with vistas to the synthesis of natural products and biologically active substrates.
2020 ◽
Vol 17
(2)
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pp. 82-90
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Keyword(s):
2006 ◽
Vol 128
(34)
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pp. 11044-11053
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Keyword(s):
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