The Use of Imaging to Detect Intracranial Tumors in Idiopathic Olfactory Dysfunction: A Systematic Review

2019 ◽  
Vol 34 (2) ◽  
pp. 297-305
Author(s):  
Jack L. Birkenbeuel ◽  
Dillon C. Cheung ◽  
Ronald Sahyouni ◽  
Khodayar Goshtasbi ◽  
Janice T. Chua ◽  
...  
Keyword(s):  
Systematic Review ◽  
Diagnostic Imaging ◽  
English Language ◽  
Screening Tool ◽  
Early Stage ◽  
Inclusion Criteria ◽  
Resonance Imaging ◽  
Detection Rates ◽  
Olfactory Loss ◽  
Ovid Medline

Objectives To review the literature regarding the use of intracranial imaging as a screening tool for idiopathic olfactory loss (IOL) and to review the incidence of identifying a sinonasal or intracranial neoplasm as a result of intracranial imaging. Methods A systematic review of published English-language literature was performed using PubMed, Ovid MEDLINE, Scopus, and Cochrane databases. Results Of the 694 available abstracts, 5 met inclusion criteria for this review. Out of 470 eligible patients, intracranial imaging identified tumors causing IOL in 8 patients (1.7%). Tumor detection rates ranged from 0% to 4.9%. Of the 470 eligible patients, intracranial imaging detected intracranial or sinonasal pathology, excluding tumors, causing IOL in 53 patients (11%). The findings ranged from 0.77% to 23%. Of the 604 eligible IOL patients, 470 (81%) underwent intracranial imaging, ranging from 53% to 100%. Conclusions In most cases, diagnostic imaging in IOL patients is frequently ordered. This study finds computed tomography or magnetic resonance imaging to be an important recommendation given to all patients with IOL. Although the overall rate of detecting tumor from diagnostic imaging is low, it is important to offer diagnostic imaging to this subset of patients to avoid missing tumors at an early stage.

scholarly journals The appropriateness of clinical decision support systems alerts in supporting clinical workflows: A systematic review

2021 ◽  
Vol 27 (2) ◽  
pp. 146045822110075
Author(s):  
Olufisayo Olusegun Olakotan ◽  
Maryati Mohd Yusof
Keyword(s):  
Systematic Review ◽  
English Language ◽  
Clinical Decision Support Systems ◽  
Clinical Decision ◽  
Inclusion Criteria ◽  
Clinical Practices ◽  
Clinical Workflow ◽  
Ovid Medline ◽  
Human Organization ◽  
Technical Framework

A CDSS generates a high number of inappropriate alerts that interrupt the clinical workflow. As a result, clinicians silence, disable, or ignore alerts, thereby undermining patient safety. Therefore, the effectiveness and appropriateness of CDSS alerts need to be evaluated. A systematic review was carried out to identify the factors that affect CDSS alert appropriateness in supporting clinical workflow. Seven electronic databases (PubMed, Scopus, ACM, Science Direct, IEEE, Ovid Medline, and Ebscohost) were searched for English language articles published between 1997 and 2018. Seventy six papers met the inclusion criteria, of which 26, 24, 15, and 11 papers are retrospective cohort, qualitative, quantitative, and mixed-method studies, respectively. The review highlights various factors influencing the appropriateness and efficiencies of CDSS alerts. These factors are categorized into technology, human, organization, and process aspects using a combination of approaches, including socio-technical framework, five rights of CDSS, and Lean. Most CDSS alerts were not properly designed based on human factor methods and principles, explaining high alert overrides in clinical practices. The identified factors and recommendations from the review may offer valuable insights into how CDSS alerts can be designed appropriately to support clinical workflow.

scholarly journals Barriers to Implementing the ACGME Outcome Project: A Systematic Review of Program Director Surveys

2012 ◽  
Vol 4 (4) ◽  
pp. 425-433 ◽  
Author(s):  
Mohammad U. Malik ◽  
David A. Diaz Voss Varela ◽  
Charles M. Stewart ◽  
Kulsoom Laeeq ◽  
Gayane Yenokyan ◽  
...  
Keyword(s):  
Systematic Review ◽  
English Language ◽  
Medical Knowledge ◽  
Program Directors ◽  
Faculty Support ◽  
Inclusion Criteria ◽  
Competency Based Education ◽  
Inadequate Knowledge ◽  
Competency Based

Abstract Introduction The Accreditation Council for Graduate Medical Education (ACGME) introduced the Outcome Project in July 2001 to improve the quality of resident education through competency-based learning. The purpose of this systematic review is to determine and explore the perceptions of program directors regarding challenges to implementing the ACGME Outcome Project. Methods We used the PubMed and Web of Science databases and bibliographies for English-language articles published between January 1, 2001, and February 17, 2012. Studies were included if they described program directors' opinions on (1) barriers encountered when attempting to implement ACGME competency-based education, and (2) assessment methods that each residency program was using to implement competency-based education. Articles meeting the inclusion criteria were screened by 2 researchers. The grading criterion was created by the authors and used to assess the quality of each study. Results The survey-based data reported the opinions of 1076 program directors. Barriers that were encountered include: (1) lack of time; (2) lack of faculty support; (3) resistance of residents to the Outcome Project; (4) insufficient funding; (5) perceived low priority for the Outcome Project; (6) inadequate salary incentive; and (7) inadequate knowledge of the competencies. Of the 6 competencies, those pertaining to patient care and medical knowledge received the most responses from program directors and were given highest priority. Conclusions The reviewed literature revealed that time and financial constraints were the most important barriers encountered when implementing the ACGME Outcome Project.

Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review

2020 ◽  
Author(s):  
Elisa T. Bushman ◽  
Gabriella Cozzi ◽  
Rachel G. Sinkey ◽  
Catherine H. Smith ◽  
Michael W. Varner ◽  
...  
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
English Language ◽  
Statistical Significance ◽  
Cochrane Library ◽  
Control Group ◽  
Inclusion Criteria ◽  
Headache Diagnosis ◽  
Registration Number ◽  
In Pregnancy

Abstract Objective Headaches affect 88% of reproductive-aged women. Yet data are limited addressing treatment of headache in pregnancy. While many women experience improvement in pregnancy, primary and secondary headaches can develop. Consequently, pregnancy is a time when headache diagnosis can influence maternal and fetal interventions. This study was aimed to summarize existing randomized control trials (RCTs) addressing headache treatment in pregnancy. Study Design We searched PubMed, CINAHL, EMBASE, ClinicalTrials.gov, Cochrane Library, CINAHL, and SCOPUS from January 1, 1970 through June 31, 2019. Studies were eligible if they were English-language RCTs addressing treatment of headache in pregnancy. Conference abstracts and studies investigating postpartum headache were excluded. Three authors reviewed English-language RCTs addressing treatment of antepartum headache. To be included, all authors agreed each article to meet the following criteria: predefined control group, participants underwent randomization, and treatment of headache occurred in the antepartum period. If inclusion criteria were met no exclusions were made. Our systematic review registration number was CRD42019135874. Results A total of 193 studies were reviewed. Of the three that met inclusion criteria all were small, with follow-up designed to measure pain reduction and showed statistical significance. Conclusion Our systematic review of RCTs evaluating treatment of headache in pregnancy revealed only three studies. This paucity of data limits treatment, puts women at risk for worsening headache disorders, and delays diagnosis placing both the mother and fetus at risk for complications.

scholarly journals Yoga as an Alternative and Complementary Treatment for Patients With Low Back Pain

2012 ◽  
Vol 18 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Manoj Sharma ◽  
Taj Haider
Keyword(s):  
Systematic Review ◽  
Low Back Pain ◽  
Back Pain ◽  
English Language ◽  
Holistic Approach ◽  
The United States ◽  
Low Back ◽  
Inclusion Criteria ◽  
Complementary Treatment ◽  
Study Inclusion

Low back pain is not only a leading cause of disability in the United States but also one of the most expensive to treat. Exercise proves to be inconsistent, and surgery often leads to disease reappearance. Yoga offers a holistic approach to overcome the psychological and physical aspects of low back pain. A systematic review was performed to determine the efficacy of yoga for low back pain. Study inclusion criteria were studies ( a) published in the English language, ( b) published between January 2000 and June 2012, ( c) included any form of yoga as an intervention, ( d) used any quantitative study design, and (5) measured low back pain as an outcome. Of the 13 studies included, 9 demonstrated a reduction in low back pain using yoga as part of the intervention. Limitations include lack of theory-based approaches, unclear definitions of low back pain, and multiple instruments used to measure the outcome.

Tai Chi as an Alternative or Complementary Therapy for Patients With Depression

2012 ◽  
Vol 18 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Manoj Sharma ◽  
Taj Haider
Keyword(s):  
Systematic Review ◽  
Disease Burden ◽  
English Language ◽  
Tai Chi ◽  
Alternative Therapy ◽  
Holistic Approach ◽  
Complementary Therapy ◽  
Assessment Tools ◽  
Inclusion Criteria ◽  
Complementary Treatment

Considering depression ranks high among the contributors to worldwide disease burden and conventional treatments have severe limitations, Tai Chi, due to its holistic approach, is being explored as an alternative therapy. A systematic review was conducted to determine the efficacy of Tai Chi as a treatment option for depression. Inclusion criteria included the following: ( a) studies published in the English language, ( b) studies published between January 2007 and July 2012, ( c) studies that included Tai Chi as a therapy in an intervention, ( d) studies that used any quantitative study design, and ( e) studies that measured depression as an outcome. A total of 11 studies met these criteria. The efficacy of Tai Chi as an alternative and complementary treatment for depression is mixed. Limitations of the reviewed interventions included a mixed usage of instruments, high dropout rates, low sample sizes, and a lack of quality assessment tools for Tai Chi.

scholarly journals Diagnostic algorithm for psoriatic arthritis in clinical practice of dermatologist

2016 ◽  
Vol 19 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Maria N. Chamurlieva ◽  
T. V Korotaeva ◽  
E. Yu Loginova ◽  
E. A Batkaev
Keyword(s):  
Psoriatic Arthritis ◽  
Screening Tool ◽  
Ultrasound Examination ◽  
Early Stage ◽  
Diagnostic Algorithm ◽  
Positive Answer ◽  
Classification Criteria ◽  
Newly Diagnosed ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

The study was carried out in 103 patients with psoriasis, who had the consultation of dermatologist and rheumatologist. Answers for 6 questions mPEST (Psoriasis Epydemiology Screening Tool) modified questionnaire were estimated, each positive answer corresponded to 1, PEST ≥ 3 was suggested the presence of psoriatic arthritis (PsA), PEST < 3 was considered the absence of PsA. All the patients were examined by rheumatologist, the gold standard was CASPAR (ClASsification criteria for Psoriatic Arthritis) criteria. If necessary the instrumental tests were performed: roentgenography, ultrasound examination, magnetic resonance imaging (MRI) and laboratory tests. At PEST ≥ 3 diagnosis of PsA was suspected in 60 (58.2%) of 103 patients. Diagnosis of PsA was confirmed by CASPAR criteria in 47 (45.6%) patients. mPEST less than 3 was in 43 (41.7%) of 103 patients. Diagnosis of PsA was absent by CASPAR criteria in 29 (67.4%) patients. Newly diagnosed PsA was in 32 (52.4%) of 61 patients. Any rheumatic disease, mainly PsA, can develop with psoriasis. mPEST questionnaire in most cases reveals PsA in early stage, however, its isolated use is insufficient to establish an accurate diagnosis, it requires a clear diagnostic algorithm of the disease, including consultation of rheumatologist, clinical and instrumental examination.

scholarly journals SARS-CoV-2 Detection in Different Respiratory Sites: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Abbas Mohammadi ◽  
Elmira Esmaeilzadeh ◽  
Yijia Li ◽  
Ronald J Bosch ◽  
Jonathan Li
Keyword(s):  
Systematic Review ◽  
Symptom Onset ◽  
Meta Analysis ◽  
Nasopharyngeal Swab ◽  
Inclusion Criteria ◽  
Rna Detection ◽  
Timely Initiation ◽  
Detection Rates ◽  
Diverse Range ◽  
Oropharyngeal Swab

Background: The accurate detection of SARS-CoV-2 through respiratory sampling is critical for the prevention of further transmission and the timely initiation of treatment for COVID-19. There is a diverse range of SARS-CoV-2 detection rates in reported studies, with uncertainty as to the optimal sampling strategy for COVID-19 diagnosis and monitoring. Methods: We performed a systematic review and meta-analysis of studies comparing respiratory sampling strategies for the detection of SARS-CoV-2 RNA. The inclusion criteria were studies that assessed at least two respiratory sampling sites (oropharyngeal swab, nasopharyngeal swab, and sputum) in participants with COVID-19. The percentage positive tests were compared between sampling modalities by constructing a Z-test assuming independence and using the standard errors obtained from the random effects meta-analysis. Findings: From 1039 total studies, we identified 11 studies that met our inclusion criteria, with SARS-CoV-2 testing results from a total of 3442 respiratory tract specimens. Compared to nasopharyngeal swab sampling, sputum testing resulted in significantly higher rates of SARS-CoV-2 RNA detection while oropharyngeal swab testing had lower rates of viral RNA detection. Earlier sampling after symptom onset was associated with improved detection rates, but the differences in SARS-CoV-2 RNA detection by sampling method was consistent regardless of the duration of symptoms. Interpretation: The results support sputum sampling as a primary method of COVID-19 diagnosis and monitoring, and highlight the importance of early testing after symptom onset to increase the rates of COVID-19 diagnosis.

scholarly journals Mammogram: Association of Music with Anxiety among Malaysian Woman – A Systematic Review.

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Nur Fatin Ruslizam ◽  
Nur Nadiah Fatihah Ab Malek ◽  
Norhayati Mohd Zain ◽  
Nur Anis Izzati Che Nut ◽  
Norhashimah Mohd Norsuddin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Cancer Pain ◽  
Music Therapy ◽  
Mammography Screening ◽  
Screening Tool ◽  
Early Stage ◽  
Database Search ◽  
X Ray ◽  
Detect Breast Cancer

Mammography is one of the screening tool that using x-ray dose to detect breast cancer at early stage for women older than 40 years old. By performing mammography screening annually, it can decrease mortality from breast cancer. Pain and anxiety often a hindrance to the rate of intake of mammography screening among the women. A systematic review was conducted to know the association of music with anxiety and pain on patients during mammography screening. Review identification was performed through a database search on MEDLINE and CINAHL, and 2 qualified studies were selected. The keyword used is “music therapy”, “anxiety”, ‘pain”, and “mammography”. A total of 2 articles showed the use of music among women who undergoing mammography screening. The previous studies showed that the use of music can decrease level of pain and anxiety among women during mammography screening. Thus, applying music during the screening should be implemented to encourage women for annual mammography screening.

scholarly journals Relationship of prostate cancer topography and tumour conspicuity on multiparametric magnetic resonance imaging: a protocol for a systematic review and meta-analysis

BMJ Open ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. e050376
Author(s):  
Pranav Satish ◽  
Alex Freeman ◽  
Daniel Kelly ◽  
Alex Kirkham ◽  
Clement Orczyk ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Systematic Review ◽  
Magnetic Resonance ◽  
English Language ◽  
Data Extraction ◽  
Meta Analysis ◽  
Resonance Imaging ◽  
Multiparametric Magnetic Resonance Imaging ◽  
Meta Analyses

IntroductionMultiparametric magnetic resonance imaging (mpMRI) has improved the triage of men with suspected prostate cancer, through precision prebiopsy identification of clinically significant disease. While multiple important characteristics, including tumour grade and size have been shown to affect conspicuity on mpMRI, tumour location and association with mpMRI visibility is an underexplored facet of this field. Therefore, the objective of this systematic review and meta-analysis is to collate the extant evidence comparing MRI performance between different locations within the prostate in men with existing or suspected prostate cancer. This review will help clarify mechanisms that underpin whether a tumour is visible, and the prognostic implications of our findings.Methods and analysisThe databases MEDLINE, PubMed, Embase and Cochrane will be systematically searched for relevant studies. Eligible studies will be full-text English-language articles that examine the effect of zonal location on mpMRI conspicuity. Two reviewers will perform study selection, data extraction and quality assessment. A third reviewer will be involved if consensus is not achieved. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines will inform the methodology and reporting of the review. Study bias will be assessed using a modified Newcastle-Ottawa scale. A thematic approach will be used to synthesise key location-based factors associated with mpMRI conspicuity. A meta-analysis will be conducted to form a pooled value of the sensitivity and specificity of mpMRI at different tumour locations.Ethics and disseminationEthical approval is not required as it is a protocol for a systematic review. Findings will be disseminated through peer-reviewed publications and conference presentations.PROSPERO registration numberCRD42021228087.

scholarly journals Patients With Diabetes Mellitus Have a Higher Risk of Tendon Retear After Arthroscopic Rotator Cuff Repair: A Meta-analysis

2020 ◽  
Vol 8 (11) ◽  
pp. 232596712096140 ◽  
Author(s):  
Chih-Kai Hong ◽  
Chao-Jui Chang ◽  
Fa-Chuan Kuan ◽  
Kai-Lan Hsu ◽  
Yueh Chen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Rotator Cuff ◽  
Rotator Cuff Repair ◽  
English Language ◽  
Arthroscopic Rotator Cuff Repair ◽  
Inclusion Criteria ◽  
Level Of Evidence ◽  
Arthroscopic Rotator Cuff ◽  
Cuff Repair

Background: Retear of a repaired rotator cuff tendon is a major issue for shoulder surgeons. It is possible that diabetes mellitus (DM) is associated with a greater risk of tendon retear after arthroscopic rotator cuff repair. Purpose: To determine whether patients with DM have a higher tendon retear risk after arthroscopic rotator cuff repair. Study Design: Systematic review; Level of evidence, 4. Methods: A systematic review was conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines using the Web of Science, PubMed, and Embase databases. Inclusion criteria were articles written in the English language that included patients undergoing arthroscopic rotator cuff repair surgeries, reported the numbers of patients with and those without DM, and reported the number of rotator cuff retears. Data relevant to this study were extracted and statistically analyzed. Random-effects models were used to generate pooled odds ratio estimates and CIs. Results: A total of 160 studies were identified from the initial search, and 5 of them met the inclusion criteria. A total of 1065 patients (207 patients with DM and 858 patients without DM) were included. The pooled results showed that the patients in the DM group had a significantly higher tendon retear risk than did those in the non-DM group (relative risk, 2.25; 95% CI, 1.14-4.45; P = .02). Conclusion: Patients with DM have a 2.25 times higher risk of tendon retear after arthroscopic rotator cuff repair compared with patients without DM.

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