Risonanza magnetica e H-MRS dell'encefalo in soggetti con LES ad esordio pediatrico

1997 ◽  
Vol 10 (2_suppl) ◽  
pp. 28-30 ◽  
Author(s):  
M. Mortilla ◽  
M. Ermini ◽  
M. Nistri ◽  
G. Dal Pozzo ◽  
F. Falcini
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Risonanza Magnetica ◽  
Systemic Lupus ◽  
Non Invasive ◽  
Children And Young Adults ◽  
Severity Of The Disease ◽  
Invasive Techniques ◽  
Metabolic Information

Systemic lupus erythematosus can produce disturbances in the CNS, characterized by seizures, headache, encephalopathy, chorea, cerebral infarction and psychosis. We used magnetic resonance and spectroscopy, in order to provide anatomical and metabolic information on the direct involvement of the CNS in LES. This study shows how these non-invasive techniques are well tolerated by children and young adults and how the levels of N-acetylaspartate correlate with the severity of the disease.

Cardiovascular magnetic resonance detects silent heart disease missed by echocardiography in systemic lupus erythematosus

Lupus ◽  
2017 ◽  
Vol 27 (4) ◽  
pp. 564-571 ◽  
Author(s):  
S Mavrogeni ◽  
L Koutsogeorgopoulou ◽  
G Markousis-Mavrogenis ◽  
A Bounas ◽  
M Tektonidou ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Cardiovascular Magnetic Resonance ◽  
Heart Disease ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Systemic Lupus

Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus

2008 ◽  
Vol 68 (9) ◽  
pp. 1478-1481 ◽  
Author(s):  
S G O’Neill ◽  
S Woldman ◽  
F Bailliard ◽  
W Norman ◽  
J McEwan ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Control Group ◽  
Systemic Lupus ◽  
Gadolinium Contrast ◽  
Cardiac Mr ◽  
Group 4 ◽  
Male Patients

Objectives:To delineate the cardiac magnetic resonance (MR) appearances of cardiovascular disease (CVD) in patients with systemic lupus erythematosus (SLE), in comparison with transthoracic echocardiographs.Methods:Cardiac MR was performed on 22 patients with SLE—11 with previous CVD and 11 matched controls—using late gadolinium contrast enhancement (LGE) to identify areas of myocardial scarring; Transthoracic echocardiography (TTE) was performed on the same day.Results:Twenty female and two male patients participated. LGE was seen in 5/11 subjects in the CVD group (4/5 with previous myocardial infarction) and 1/11 in the control group. TTE detected myocardial abnormalities in 2/6 patients with LGE.Conclusion:The cardiac MR appearance of CVD in these patients with SLE was suggestive of coronary disease, rather than cumulative inflammatory muscle damage. Cardiac MR detected more abnormalities than TTE. Further studies of cardiac MR in patients with SLE are warranted to investigate these preliminary findings.

scholarly journals Magnetic resonance imaging of the brain and cerebral proton spectroscopy in patients with systemic lupus erythematosus

1997 ◽  
Vol 40 (1) ◽  
pp. 36-46 ◽  
Author(s):  
R. J. S. Chinn ◽  
I. D. Wilkinson ◽  
M. A. Hall-Craggs ◽  
M. N. J. Paley ◽  
E. Shortall ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Systemic Lupus Erythematosus ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Resonance Imaging ◽  
Proton Spectroscopy ◽  
Systemic Lupus ◽  
The Brain

Early Diagnosis of Neuropsychiatric Systemic Lupus Erythematosus by Deep Learning Enhanced Magnetic Resonance Spectroscopy

2021 ◽  
Vol 11 (5) ◽  
pp. 1341-1347
Author(s):  
Xin Li ◽  
Lu Bai ◽  
Zuhao Ge ◽  
Zhizhe Lin ◽  
Xi Yang ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Magnetic Resonance Spectroscopy ◽  
Lupus Erythematosus ◽  
Support Vector ◽  
Resonance Spectroscopy ◽  
Systemic Lupus ◽  
Proton Mrs ◽  
Neuropsychiatric Systemic Lupus Erythematosus

The neuropsychiatric systemic lupus erythematosus (NPSLE) has higher disability and mortality rates, which is one of the main causes of death in systemic lupus erythematosus (SLE) patients. Magnetic resonance spectroscopy (MRS) can detect the changes of metabolites in different intracranial areas in vivo in patients with SLE, so as to provide evidence for the early diagnosis of NPSLE. Different from the conventional single-voxel MRS, which can only screen one brain region with one metabolic change, we simultaneously detect 13 kinds of intracranial metabolic changes in nine brain regions by multivoxel proton MRS (MVS). We use a recursive feature elimination algorithm to select the most related metabolites for better identifying NPSLE. To accurately diagnosis NPSLE by these intracranial metabolites, we train a support vector machine deep stacked network (SVM-DSN) for quantitative analysis of these metabolites. Comparing with the conventional statistic method, which is about 70% of accuracy, the proposed model achieves 97.5% of accuracy for NPSLE diagnosis. We conclude the trained SVM-DSN can effectively analyze the metabolites obtained by multivoxel proton MRS for NPSLE diagnosis, which may help to early diagnosis and intervention of NPSLE, and alleviate the bias of manual screening.

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