scholarly journals Features associated with SARS-COV-2 positivity among people presenting with acute respiratory tract infections to public Hospitals in Harari region, Ethiopia

2021 ◽  
Vol 9 ◽  
pp. 205031212110627
Author(s):  
Abdi Birhanu ◽  
Galana Mamo Ayana ◽  
Miesso Bayu ◽  
Ahmed Mohammed ◽  
Yadeta Dessie

Background: Despite investigating coronavirus among respiratory tract infected cases is a top priority to prevent further transmission, severe acute respiratory syndrome coronavirus 2 positivity among this group of patients remains unexplored in resource-limited settings. Therefore, this study intended to assess the severe acute respiratory syndrome coronavirus 2 positivity among patients presenting with acute respiratory tract infection from 1 July to 31 December 2020 in Harar Region, Ethiopia, from 15 February to 10 March 2021. Methods: A facility-based cross-sectional study design was used. Severe acute respiratory syndrome coronavirus 2 was tested by assaying oropharyngeal swabs using reverse transcriptase–polymerase chain reaction among patients presenting with acute respiratory tract infection in Harari Public Hospitals. A binary logistic regression was used to identify factors associated with severe acute respiratory syndrome coronavirus 2 positivity with an adjusted odds ratio at a 95% confidence interval. Results: Out of a total of 1692 study participants, 388 (22.9%) of them tested positive for severe acute respiratory syndrome coronavirus 2. Of these severe acute respiratory syndrome coronavirus 2 positive patients, 364 (21.6%) patients presented with lower respiratory tract infection, while the rest only 24 (1.4%) presented with upper respiratory tract infection. Independent variables included separated/divorced in marital status (AOR = 0.53, 95% CI: 0.29–0.95), presenting with cough, fever, and difficulty of breathing (AOR = 2.5, 95% CI: 1.22–4.7), age group of 30–39 years (AOR = 0.35, 95% CI: 0.15–0.79), 40–49 years (AOR = 0.37, 95% CI: 0.14–0.94), and 50–59 years (AOR = 0.31, 95% CI: 0.13–0.76) compared to patients with the age of ⩾ 60 years, had statistically significant association with severe acute respiratory syndrome coronavirus 2 positivity. Conclusion: Severe acute respiratory syndrome coronavirus 2 was positive among 388 (22.9%) acute respiratory tract infected people. Elder age, particular symptoms, such as cough, fever, and difficulty of breathing, and married marital status were associated with a severe acute respiratory syndrome coronavirus 2 positive test. In resource-limited setups, where a shortage of testing equipment is common, these findings could contribute to boosting targeted symptom-oriented screening schemes. Moreover, this study could have paramount clinical importance for further studies in the country.

2019 ◽  
Vol 67 (2) ◽  
pp. 341-347
Author(s):  
Norma Constanza Corrales-Zúñiga ◽  
Nelly Patricia Martínez-Muñoz ◽  
Sara Isabel Realpe-Cisneros ◽  
Carlos Eberth Pacichana-Agudelo ◽  
Leandro Guillermo Realpe-Cisneros ◽  
...  

Introducción. Es frecuente que muchos niños sometidos a procedimientos con anestesia general tengan historia de infección viral respiratoria superior reciente o activa.Objetivo. Realizar una revisión narrativa acerca de las pautas de manejo anestésico para los niños con infección reciente o activa de la vía aérea superior.Materiales y métodos. Se realizó una búsqueda estructurada de la literatura en las bases de datos ProQuest, EBSCO, ScienceDirect, PubMed, LILACS, Embase, Trip Database, SciELO y Cochrane Library con los términos Anesthesia AND Respiratory Tract Infections AND Complications; Anesthesia AND Upper respiratory tract infection AND Complications; Anesthesia, General AND Respiratory Tract Infections AND Complications; Anesthesia, General AND Upper respiratory tract infection AND Complications; Anesthesia AND Laryngospasm OR Bronchospasm. La búsqueda se hizo en inglés con sus equivalentes en español.Resultados. Se encontraron 56 artículos con información relevante para el desarrollo de la presente revisión.Conclusiones. Una menor manipulación de la vía aérea tiende a disminuir la frecuencia de aparición y severidad de eventos adversos respiratorios perioperatorios. No existe evidencia suficiente para recomendar la optimización medicamentosa en pacientes con infección respiratoria superior.


Author(s):  
ATIKA WAHYU PUSPITASARI ◽  
OLYVA CESSARI LARAS SERUNI ◽  
LINA NADHILAH

Objective: Acute respiratory tract infection (ARTI) is common and has the highest death rate in children, especially in growing countries such asIndonesia. The aim of the research is to identify drug-related problems (DRPs) in pediatric ARTI patients based on the DRP classification by Cipolle,Strand, and Morley, which included categories such as unnecessary drug therapy, need additional therapy, ineffective drug, dosage adjustments suchas too low or too high, and adverse drug reaction which is drug interaction.Methods: The design of the study was cross-sectional and descriptive with a retrospective method. The sample of the study was the overall prescriptionsto upper respiratory tract infection patients in Tebet Subdistrict Health Center from July to December 2018 that fulfilled all of the inclusion criteria,using the total sampling method. Total samples that were analyzed were from 179 sheets of prescription with a total of 498 prescriptions.Results: The results of the research based on each parameter were inaccurate drug selection (9.5%), inaccurate indication (12.8%), mismatched dose(79.9%), and drug interaction (0.6%).Conclusion: DRPs in ARTI pediatric patients resulted in a high-risk condition so that the health facilities need to improve their prescribing pattern andmonitor and manage each therapy as well as do a routine prescription assessment to minimize the incidence of DRPs and achieve a rational drug usage.


2021 ◽  
Author(s):  
Pinar Kiymet Karataban

Coronavirus (COVID-19) is an enveloped RNA virus with a size of ~350 kilobase-pair and COVID-19 is commonly transmitted via aerosols, saliva, nasal droplets, and surface contact which causes severe acute respiratory tract infection among infected humans, and recently many cases declared with severe blood clotting. The average incubation period ranges from 4 to 14 days. The infected person usually presents fever accompanying an upper respiratory tract infection (RTI) and complaints of dry cough, and dyspnea. It is highly recommended to keep any suspected individuals in quarantine (isolation). After its first emergence in Wuhan, China in 2019 and then intercontinental spread it was declared as a pandemic by the World Health Organization in March 2020. The pandemic of COVID-19 deeply affected the whole world and healthcare workers as front liners are most at risk among professional groups. Dentistry is among the riskiest occupational groups that include all direct and indirect ways of COVID-19 spread. In this process, the dentists who experienced the effects of COVID-19 in the working conditions, economy, and social fields were psychologically negatively affected, and their anxiety, fear, and stress levels increased. In this review, we discuss the increased risk of the spread of coronavirus during dental operative procedures and the effects of the COVID-19 pandemic on the anxiety level, depression, and mental health of dental professionals.


Author(s):  
Merry Sunaryo

Dust is one type of potential hazardzs in the workplace that can affect the health of the workers. The occupation that are always exposed to dust is furniture industry workers so that they have higher risk of getting acute respiratory tract infection (ARI) disorder which can interfere with breathing. The wood dust is formed from some of the sawn wood and sanding that will lead to an acute respiratory tract infection. The study aimed to determine the effect of environmental factor and the use of Personal Protective Equipment (PPE) against the symptoms of acute respiratory infections in the furniture industry workers. The research method used was quantitative method with observational and cross-sectional research types and it was analysed by using logistic regression test. The population in this study was the workers of the furniture industry at Semarang street, Surabaya City, with a total of 57 people, of which 37 furniture workers as a sample. The results show that most of the workers has symptoms of acute respiratory tract infection. It could be influenced by the environmental factor such as dust exposure that produced wood dust in each manufacturing processes. Additionally, the use of PPE also affected the occurrence of acute respiratory tract infections symptoms in the workers. In conslusion, many factors can influence the occurrence of acute respiratory tract infection symptoms in the furniture industry workers. Therefore, it is necessary to minimize the dust exposure in workers by wearing PPE such as respirators.


2014 ◽  
Vol 5 (4) ◽  
pp. 34-38
Author(s):  
Mahesh B Tondare ◽  
VV Raje ◽  
Sachin Mumbare ◽  
MV Rayate ◽  
Sangamesh Tondare ◽  
...  

Background: Malnutrition and infectious diseases both occur in the same unfortunate children and together they play a major role in causing the high morbidity and mortality in them.In developing countries, mortality from ARTI is 30?70 times higher than in developed countries and it has been estimated that up to 1/3rd of all deaths in children less than 5 years are attributed to ARTI. Aims & Objectives: This study aimed to find the attack rate of Acute Respiratory Tract infection and the socio?demographic variables of pre?school children suffering from Acute Respiratory Tract infections. Method: A Comparative Longitudinal study was carried out among preschool children (3?5 years) who were selected from Private pre?primary school of urban area (155)& Anganwadis (157) of urban slum area of karad town and followed for the period of one year. Mother/guardian/teacher was interviewed by using pre?tested proforma during this period. Results & Interpretation: out of all 97.4% of private pre?primary school children had 1.8 episodes/child/year of ARTI compared to Anganwadi children where all of them had 2.5 episodes/child/year of ARTI. Conclusion: Maximum number of children from private pre?primary schools from urban area also suffered with at least one episode of Acute Respiratory Tract Infection compared to Anganwadi children from urban slum areas. DOI: http://dx.doi.org/10.3126/ajms.v5i4.10044 Asian Journal of Medical Sciences 2014 Vol.5(4); 34-38


Author(s):  
Imam Santoso ◽  
Darmiah Darmiah

Abstract: Relationship of Carbon Monoxide Pollution in House With The Upper Respiratory Tract infection In Desa Sungai Alat Kabupaten Banjar. The data showed 64.2 % of households in South Kalimantan residents use charcoal and firewood for cooking, so the room in a house filled with smoke. In addition to the state of the smoke could also come from outside , because the habits of the people who set fire to dry land in the dry season. This phenomenon is predicted to be potential risk of respiratory tract infections. This study aims to determine the relationship of carbon monoxide pollution in homes with the upper respiratory tract infection in Desa Sungai Alat Kabupaten Banjar. Using cross sectional study design. The number of samples taken 28 infants in total population. Analysis used logistic regression. The results of the research data showed levels of CO in the average house of 0.42 mg / m3 in the range of 0.19 to 1.62 mg / m3 . The number of infants who suffer from respiratory 42.9 %. Houses that use firewood as much as 53.6 % , and home to the unhealthy category as much as 78.6 % . Temperatures in the average home 32.6 0C , and air humidity in the average home 71.41 %. Bivariate analysis using logistic regression, there was no significant association between levels of CO with the upper respiratory tract infection in infants ; similarly no significant association between the control variables with the dependent variable. To do a home assessment form should be conducted validity assessment. In further studies the expected number of samples propagated to the toddler . Keywords: pollution , carbon monoxide , upper respiratory tract infection   


PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11109
Author(s):  
Xulong Cai ◽  
Qiaolan Xu ◽  
Chenrong Zhou ◽  
Tongjin Yin ◽  
Li Zhou

Background Due to the lack of effective and feasible viral biomarkers to distinguish viral infection from bacterial infection, children often receive unnecessary antibiotic treatment. To identify serum β2-microglobulin that distinguishes bacterial upper respiratory tract infection from viral upper respiratory tract infection and exanthem subitum in children. Methods This retrospective study was conducted from January 1, 2019 to September 30, 2020 in Yancheng Third People’s Hospital. Children with upper respiratory tract infection and exanthem subitum were recruited. The concentration of serum β2-microglobulin in the viral and bacterial infection groups were statistically analyzed. Results A total of 291 children included 36 with bacterial upper respiratory tract infection (median age, 13 months; 44.4% female), 197 with viral upper respiratory tract infection (median age, 12 months; 43.7% female) and 58 with exanthem subitum (median age, 13 months; 37.9% female). When the concentration of β2-microglobulin was 2.4mg/L, the sensitivity to distinguish viral from bacterial upper respiratory tract infection was 81.2% (95% CI [75.1–86.4%]), and the specificity was 80.6% (95% CI [64.0–91.8]%). When the cutoff was 2.91 mg/L, the sensitivity of β2-microglobulin to distinguish exanthem subitum from bacterial upper respiratory tract infection was 94.8% (95% CI [85.6–98.9]%), and the specificity was 100% (95% CI [90.3–100]%). Conclusions Serum β2-microglobulin may be a significant biological indicator in children with upper respiratory tract infection and exanthem subitum.


2012 ◽  
Vol 2 ◽  
pp. 1
Author(s):  
Sumreen Javed ◽  

Respiratory tract infections are the most common infections in the developing countries. Its mode of spread is also very fast as compared to any other infection. Therefore; we have aimed this study based on the administration of two different drugs, Ciprox (Ciprofloxacin) and Augmentin (amoxicillin/clavulanate potassium), for the treatment of upper respiratory tract infection.


2018 ◽  
Vol 14 (1) ◽  
pp. 27-33
Author(s):  
Tesar Zulmi Antoro ◽  
Nurul Mutmainah

Acute respiratory tract infection is an acute infection which attacks one or more part of respiratory tractfrom nose to alveoli. This disease is an important society’s health problem especially in the developingcountries which attacks children easily especially who have low body’s immunity. This aim of the researchwas to know representation of the treatment and the accuracy of antibiotics distribution as the treatment ofpediatric patients of acute upper respiratory tract infection (AURTI) at Health Center in Kunduran, Blora2013 which is observed by appropriate parameter indication, appropriate drugs, appropriate dose andappropriate patients using the standard from WHO (2003). This research was categorized as qualitativeand non experimental research. In obtaining the data, the researcher trace the pediatric patient’s medicalrecord in the registration book in the health center Kunduran, Blora regency year 2013. The obtained datawas analyzed descriptively to evaluate the rationality of antibiotics distribution for AURTI. The researchresult showed that over 110 of the available samples in children aged up to 12 years old which werediagnosed as AURTI sufferer, 92 cases (83.63%) used amoxicillin antibiotics, 18 cases (16.37%) usedkotrimoksazol, 72 cases (65.50%) were proper indication, 59 case (53.63%) were proper drugs, 110 cases(100%) were proper patients, 87 case (79.09%) were proper dose, and 47 case (42.70) were rational in thetreatment


Author(s):  
Rafea B. ◽  
Alharbi F. ◽  
Alhazmi G. ◽  
Alahmadi L. ◽  
Almotiri M. ◽  
...  

Introduction: In general practice, approximately two-thirds of antibiotic prescriptions are for respiratory tract infections. Acute respiratory tract infections, which include acute uncomplicated bronchitis, pharyngitis, rhinosinusitis and the common cold, are often common reasons for acute outpatient visits to physicians and antibiotic prescriptions for adults. The improper treatment of acute respiratory tract infections is now an urgent public health threat, as it is an important contributor to antibiotic resistance. In developing countries, including Saudi Arabia, antibiotics are prescribed excessively and are often obtained without prescription. Aim: The aim of this study was to gather information on current antibiotic prescribing rates for respiratory tract infection in Hera General Hospital Makkah Almukarramah, Saudi Arabia. Method: A cross-sectional study, incorporating systematic sampling on clinical data from antibiotic prescriptions in hospitalised and emergency departments at Hera General Hospital, was conducted. From September 2017 to April 2018, approximately 500 prescriptions were collected from each hospitalised and emergency pharmacy for patients with respiratory tract infections. Results: The most prescribed antibiotics for respiratory tract infections came from the penicillin group and ciprofloxacin. The prescribing of antibiotics for respiratory tract infections was more prevalent amongst males than females. Potential over-prescribing of antibiotics for upper respiratory tract infections specially patients with otitis media especially in children without proper lab investigations.


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