scholarly journals Linear porokeratosis presenting in adulthood: A diagnostic challenge: A case report

2020 ◽  
Vol 8 ◽  
pp. 2050313X2091961
Author(s):  
Roya S Nazarian ◽  
Mojgan Hosseinipour ◽  
Bijal Amin ◽  
Steven R Cohen
Keyword(s):  
Case Report ◽  
Rare Variant ◽  
Somatic Mutation ◽  
Clinical Presentation ◽  
Adult Onset ◽  
Diagnostic Challenge ◽  
Distal Extremity ◽  
Proximal Extremity ◽  
Oral Isotretinoin ◽  
Children Development

Linear porokeratosis is a rare variant of porokeratosis that most often presents in newborns and children; development of this porokeratosis variant in adulthood is far less common. We report the case of a 25-year-old female who presented with a progressive eruption on the proximal upper extremity of 6-year duration, which was ultimately diagnosed as adult-onset linear porokeratosis and safely treated with oral isotretinoin. We propose that a sporadic mutation resulting in mosaicism after birth may explain the development of linear porokeratosis in adulthood, although the exact trigger of such a somatic mutation is not known. This case also describes a unique clinical presentation, with linear porokeratosis lesions originating on the proximal extremity rather than on the more common distal extremity. This demonstrates a distinctive clinical presentation not seen in the pediatric forms of disease.

scholarly journals ADULT - ONSET STILL'S DISEASE OR MULTISYSTEMIC INFLAMMATORY SYNDROME: A DIAGNOSTIC CHALLENGE AFTER PANDEMIC – CASE REPORT

2021 ◽  
Author(s):  
Daniela Esteves Temporim ◽  
Matheus Zanata Brufatto ◽  
Sean Hideo Shirata Lanças ◽  
Andrea de Almeida Peduti Batista ◽  
Laura Maria Silva de Siqueira ◽  
...  
Keyword(s):  
Case Report ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Diagnostic Challenge ◽  
Still's Disease ◽  
Inflammatory Syndrome ◽  
Adult Onset Still's Disease

Rhinoscleroma: A Case Report and Clinical Update

1993 ◽  
Vol 7 (6) ◽  
pp. 281-286
Author(s):  
Welby Winstead ◽  
Thomas V. Connely ◽  
Martin J. Raff
Keyword(s):  
Case Report ◽  
Respiratory Tract ◽  
Clinical Presentation ◽  
High Dose ◽  
Diagnostic Challenge ◽  
Acute Symptom ◽  
High Dose Treatment ◽  
The World ◽  
The U.S ◽  
Laryngeal Involvement

Rhinoscleroma is a chronic granulomatous inflammatory disease caused by Klebsiella rhinoscleromatis. Initially described as a lesion of the nose, rhinoscleroma may involve any part of the respiratory tract. Although it is endemic in many parts of the world, rhinoscleroma has been rarely recognized in the U.S. In this report, we present a case of rhinoscleroma that illustrates the diagnostic challenge and therapeutic dilemma this disease presents. The significance of laryngeal involvement is emphasized. We review the clinical presentation, diagnosis, and treatment of rhinoscleroma. Ciprofloxacin was found effective in controlling acute symptom; however, longterm, high dose treatment has not been curative.

scholarly journals Isolated intraventricular conduction delay in fulminant myocarditis: A case report

2020 ◽  
pp. 102490792091152
Author(s):  
Yat Hei Lo ◽  
Yau Tak Wong
Keyword(s):  
Emergency Department ◽  
Case Report ◽  
Clinical Presentation ◽  
Fulminant Myocarditis ◽  
Conduction Delay ◽  
Diagnostic Challenge ◽  
Intraventricular Conduction ◽  
Wide Range ◽  
Intraventricular Conduction Delay ◽  
Acute Inflammatory Cell

Introduction: Fulminant myocarditis is uncommon. Making the diagnosis in the emergency department is difficult due to the nonspecific clinical presentation and electrocardiogram results. Case presentation: A 58-year-old Chinese woman presented to an emergency department with dizziness and malaise for 2 days. She was hypotensive and afebrile. Initial electrocardiogram showed isolated nonspecific intraventricular conduction delay. Despite resuscitation, she rapidly deteriorated in the emergency department and eventually succumbed. Autopsy and histological examination of heart muscle found acute inflammatory cell infiltration and multifocal necrosis, suggestive of acute fulminant myocarditis. Discussion: There is a wide range of differential diagnosis of nonspecific intraventricular conduction delay. Clinical presentation of mycoarditis is also often non-specific. Rapid and accurate recognition of the condition is essential to save life. Conclusion: Fulminant myocarditis presenting with cardiogenic shock and isolated intraventricular conduction delay on electrocardiogram poses a diagnostic challenge as illustrated in this case report.

scholarly journals Subungual Squamous Cell Carcinoma: The Diagnostic Challenge and Clinical Pearls

2016 ◽  
Vol 8 (3) ◽  
pp. 272-277 ◽  
Author(s):  
Wai Leong Kok ◽  
Joyce Siong See Lee ◽  
Martin Tze-wei Chio
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical Presentation ◽  
Practical Approach ◽  
Rare Entity ◽  
Diagnostic Challenge ◽  
Clinical Index ◽  
Subungual Squamous Cell Carcinoma

Subungual squamous cell carcinoma is a rare entity and difficult to diagnose as its clinical presentation may resemble benign conditions. This case report highlights the need to maintain a high clinical index of suspicion, and recommends a practical approach for subungual conditions. Dermoscopy and a biopsy for histology are important adjuncts to clinch the diagnosis.

A Case Report of Synovial Hemangioma: A Rare Cause of Opacity in Hoffa’s Fat Pad

2019 ◽  
Vol 1 ◽  
pp. 127-130
Author(s):  
Saurabh Maheshwari ◽  
Samar Chatterjee ◽  
U. Rajesh ◽  
Prateek ◽  
Vivek Khandelwal
Keyword(s):  
Case Report ◽  
Clinical Presentation ◽  
Infrapatellar Fat Pad ◽  
Injection Sclerotherapy ◽  
Fat Pad ◽  
Common Site ◽  
Ultrasound Guided ◽  
Diagnostic Challenge ◽  
Synovial Hemangioma ◽  
Inflammatory Processes

The infrapatellar fat pad of Hoffa is an intracapsular structure which is a common site for inflammatory processes. However, it can also be involved by neoplastic pathologies. We report a case of synovial hemangioma in this location which presented a diagnostic challenge due to unusual clinical presentation. The patient was managed with multiple sessions of ultrasound-guided injection sclerotherapy with partial resolution of the lesion.

scholarly journals Hemoophagocitic Lymphohistiocytosis a Case Report

2021 ◽  
pp. 1-3
Author(s):  
Marsela Shani ◽  
Keyword(s):  
Case Report ◽  
Clinical Presentation ◽  
Therapeutic Agents ◽  
Evidence Based ◽  
Adult Onset ◽  
Delay In Diagnosis ◽  
Current State ◽  
Familial Form ◽  
Threatening Condition ◽  
Life Threatening

Hemophagocytic lymphohistiocytosis (HLH), a rare but life-threatening condition characterized by uncontrolled inflammation, is increasingly recognized in adults. The management of adult onset HLH is challenging, in part due to gaps in current state of knowledge on etiology, clinical presentation, diagnosis, and management. HLH secondary to triggers such as infections, autoimmune disorders, and malignancy are more commonly seen in adults although cases of familial form have also been reported. Underlying conditions such as sepsis, or malignancy could pose as major confounders while applying universal diagnostic criteria, and therefore could lead to delay in diagnosis. Despite advent of newer therapeutic agents, outcomes of adults continue to remain poor. Future efforts need to be orchestrated to develop evidence-based tailored therapies to improve outcomes of this under recognized heterogeneous entity.

scholarly journals Tinea incognito: Report of two cases

1970 ◽  
Vol 6 (3) ◽  
pp. 46-49
Author(s):  
SK Kedia ◽  
M Mathur
Keyword(s):  
Case Report ◽  
Fungal Infection ◽  
Clinical Presentation ◽  
Topical Steroid ◽  
Medical Sciences ◽  
Diagnostic Challenge ◽  
Over The Counter ◽  
Inappropriate Use ◽  
General Physicians ◽  
Tinea Incognito

Tinea incognito remains diagnostic challenge even to expert specialist because of modified clinical presentation caused by of inappropriate use of topical steroid. Topical steroid are being prescribed frequently for vary many dermatosis including fungal infection of skin and being used by patient as "over the counter drug" leading to varied clinical presentation of common dermatosis. This case report is of iatrogenic dermatosis that was invariably misdiagnosed by general physicians. Key words: Tinea incognito; dermatosis; fungal infection. DOI: 10.3126/jcmsn.v6i3.4076Journal of College of Medical Sciences-Nepal, 2010, Vol. 6, No. 3 pp.46-49

Myxoid atypical fibroxanthoma: a challenging diagnosis of a rare variant: Case report

2020 ◽  
pp. 399-403
Author(s):  
Nikolina Stavrinou ◽  
Stavroula Papadopoulou ◽  
Georgia Mitropoulou ◽  
Helen Trihia ◽  
Ioannis Provatas
Keyword(s):  
Case Report ◽  
Rare Variant ◽  
Atypical Fibroxanthoma
Sign in / Sign up

Export Citation Format

Share Document