scholarly journals “Long COVID”: A case report of persistent symptoms in a patient with prolonged SARS-CoV-2 shedding for over 110 days

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110154
Author(s):  
Ayanfe Omololu ◽  
Barakah Ojelade ◽  
Oluwatomiwa Ajayi ◽  
Tolu Adesomi ◽  
Oreoluwa Alade ◽  
...  
Keyword(s):  
Health Care ◽  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Musculoskeletal Symptoms ◽  
Viral Shedding ◽  
Persistent Symptoms ◽  
The World ◽  
Care Worker

Coronavirus disease 2019 is a novel disease currently ravaging the world as a pandemic. More emphasis has been focused on the acute disease, with less attention on the detection and management of long-term sequelae which develop in some patients, variously termed “Long COVID,” Post-coronavirus disease 2019 syndrome, or ongoing coronavirus disease. There are also various reports in the literature on the duration of viral shedding, with the longest known recorded being about 70 days, and whether this duration has an effect on prognosis or patients remaining infectious is still unknown. We report the case of a 22-year-old health care worker with prolonged multi-systemic features of coronavirus disease 2019 including cardiovascular, respiratory, central nervous system, and musculoskeletal symptoms lasting about 18 weeks from symptom onset, though never hospitalized, and persistent detection of severe acute respiratory syndrome coronavirus 2 attributed to viral shedding for over 110 days, which is the longest duration recorded to our knowledge.

Acute Pancreatitis Following Organophosphate Compound Poisoning: A Case Report

2021 ◽  
Vol 1 (4) ◽  
pp. 250-252
Author(s):  
Suman K. Jha ◽  
Sabin Chaulagain ◽  
Shiva Kumar Ojha ◽  
Angela Basnet Neela Sunuwar ◽  
Akanchha Khadka
Keyword(s):  
Central Nervous System ◽  
Acute Pancreatitis ◽  
Nervous System ◽  
Case Report ◽  
Rural Communities ◽  
South Asian ◽  
Asian Countries ◽  
Organophosphate Compounds ◽  
The World ◽  
Agrarian Communities

Organophosphate compounds are chemicals containing central phosphate molecules with alkyl or aromatic substituent’s. They occur in diverse forms and are used as pesticides, herbicides, nerve agents, etc. Organophosphate compounds are frequently used as pesticides in agrarian communities all across the world. South Asian countries such as Nepal use vast quantities of Organophosphate compounds for pest control in agriculture. Therefore, accidental and suicidal ingestion of Organophosphate compound poisoning has been common especially among the agricultural rural communities. Apart from muscarinic, nicotinic and central nervous system effects in rare instances, Organophosphate compounds are known to cause pancreatitis.

scholarly journals Hospital Preparedness and Response Framework during infection pandemic.

2021 ◽  
Author(s):  
Bikash Bikram Thapa
Keyword(s):  
Health Care ◽  
Health Policy ◽  
Social Life ◽  
World Health ◽  
Health Economy ◽  
The World ◽  
Hospital Preparedness ◽  
Long Term Consequences ◽  
Care Worker

Coronavirus disease 2019 (COVID-19) has put an unprecedented burden to world health, economy and social life with possible long-term consequences. The velocity and mass of this infection pandemic had already overwhelmed every robust health care system in the world. The evidence pertaining to this novel infection pandemic is evolving, so are the challenges in terms of adequate preparedness and response. In this review, we enumerate the strategic and operational domains and build a functional framework for the management of hospital mass infection incidents due to COVID-19 and similar future pandemics. This functional framework could assist health policy maker and health care worker to implement, innovate, and translate preparedness and response to save valuable life and resources.

Whipple Disease: A Case Report and Review of the Literature

2005 ◽  
Vol 129 (7) ◽  
pp. 933-936
Author(s):  
M. A. J. Jeannie Muir-Padilla ◽  
C. O. L. Jerome B. Myers
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Central Nervous System Involvement ◽  
Tropheryma Whipplei ◽  
Review Of The Literature ◽  
Diagnostic Challenge ◽  
Multisystem Disease ◽  
Whipple Disease

Abstract Whipple disease is a chronic, relapsing, and multisystem disease. It presents a diagnostic challenge for both clinicians and pathologists. Recent advances in isolation and culture have identified the organism responsible for the disease to be a member of the order Actinomycetes designated Tropheryma whipplei. Several immune system changes have been noted in patients with Whipple disease, but whether these are primary or secondary is as yet undetermined. Long-term antibiotic therapy is required, and relapses are common, especially with central nervous system involvement.

scholarly journals Primary Central Nervous System Infection by Histoplasma in an Immunocompetent Adult: A Case Report

2021 ◽  
pp. 1-2
Author(s):  
Henry Koiti Sato ◽  
◽  
Joel Fernando Sanabria Duarte ◽  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Latin America ◽  
Case Report ◽  
Histoplasma Capsulatum ◽  
Clinical Presentation ◽  
Central Nervous System Infection ◽  
Immunocompetent Adult ◽  
Disseminated Histoplasmosis ◽  
The World

Histoplasma capsulatum infection is endemic in many regions around the world, including Latin America [1]. However, cerebral presentation occurs in less than 25% of patients with disseminated histoplasmosis and even rarer as a stand-alone presentation. Three forms are described: meningeal, miliary granulomatous and parenchymal with formation of “histoplasmoma” [2]. Due to the rarity of the case and unusual clinical presentation and topography we describe the case below.

scholarly journals Presymptomatic viral shedding and infective ability of SARS-CoV-2; a case report.

2021 ◽  
Author(s):  
Karolina Nissen ◽  
Marie Hagbom ◽  
Janina Krambrich ◽  
Dario Akaberi ◽  
Sumit Sharma ◽  
...  
Keyword(s):  
Health Care ◽  
Case Report ◽  
Health Care Worker ◽  
Symptom Onset ◽  
Cytopathic Effect ◽  
Case Reports ◽  
Igg Antibodies ◽  
Double Stranded Rna ◽  
Viral Shedding ◽  
Care Worker

Abstract Reports of possible pre- or asymptomatic transmission have been reported, both from SARS-CoV and from MERS-CoV outbreaks, although this appears to be uncommon. In contrast, during the COVID-19 pandemic, an increasing number of studies and case reports indicate that pre- or asymptomatic transmission of SARS-CoV-2 is not only possible but also occurs frequently. We report repeated rRT-PCR detection of SARS-CoV-2 in a health care worker and demonstrate infective ability up to three days prior to mild COVID-19 symptoms. rRT-PCR indicated high viral levels approximately three days after exposure. Viral samples collected one and three days prior to symptoms exhibited infectivity on Vero E6 cells, confirmed by detection of double-stranded RNA by immunofluorescence, assessment of cytopathic effect (CPE) and rRT-PCR. SARS-CoV-2 specific IgM and IgG antibodies were detected by day 9 and 15, respectively, after symptom onset. We propose that this provides evidence for potential early presymptomatic transmission of SARS-CoV-2 and that infectivity may be manifest shortly after exposure.

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