scholarly journals Adolescent COVID-19-Associated Fatal Rhabdomyolysis

2020 ◽  
Vol 11 ◽  
pp. 215013272098564
Author(s):  
Huda Anwar ◽  
Anwaar Al Lawati
Keyword(s):  
Polymerase Chain Reaction ◽  
Global Health ◽  
Respiratory Tract ◽  
Sore Throat ◽  
Shortness Of Breath ◽  
Past Medical History ◽  
Chain Reaction ◽  
Viral Illness ◽  
Polymerase Chain ◽  
High Index Of Suspicion

Coronavirus disease 2019 (COVID-19) has become an urgent global health priority. Although most patients with COVID-19 manifest with fever and respiratory tract symptoms, COVID-19 infections may also involve other organs and extrarespiratory manifestations, including cardiac, gastrointestinal, hepatic, renal, and neurological symptoms. This case describes a 16-year-old boy who presented with fever, sore throat, myalgia, and subsequently with shortness of breath. A diagnosis of COVID-19 was confirmed by polymerase chain reaction. His condition deteriorated and he died within 3 days of admission. An evaluation of his past medical history confirmed an episode of viral illness which had progressed to myositis and rhabdomyolysis 1 year prior. Clinicians should be aware of this complication and maintain a high index of suspicion in cases of COVID-19 presenting with extrapulmonary symptoms.

scholarly journals SARS–CoV-2 isolation from an appendix

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Shahzaib Ahmad ◽  
Rahim Nadeem Ahmed ◽  
Poonam Jani ◽  
Mattee Ullah ◽  
Hossam Aboulgheit
Keyword(s):  
Polymerase Chain Reaction ◽  
Abdominal Pain ◽  
Respiratory Symptoms ◽  
Tissue Sample ◽  
Gastrointestinal Symptoms ◽  
Shortness Of Breath ◽  
Chain Reaction ◽  
Histological Features ◽  
First Case ◽  
Polymerase Chain

Abstract Efforts to recognize SARS–CoV-2 infection have focused on respiratory symptoms such as cough and shortness of breath. Although it is also well known that SARS–CoV-2 infection can cause gastrointestinal symptoms such as abdominal pain, nausea, vomiting and diarrhoea, there are emerging reports of SARS–CoV-2 infection causing surgical pathology. We present the first case report of SARS–CoV-2 infection directly causing acute appendicitis, first suspected due to highly atypical histological features and later confirmed as polymerase chain reaction positive appendicular tissue sample.

scholarly journals Meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult

2016 ◽  
Vol 7 (04) ◽  
pp. 591-593 ◽  
Author(s):  
Pooja Gupta ◽  
Rajeev Ranjan ◽  
C. S. Agrawal ◽  
K Muralikrishnan ◽  
Nikhil Dave ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Healthy Male ◽  
Chain Reaction ◽  
Immunocompetent Adult ◽  
Neurological Sequelae ◽  
Varicella Zoster ◽  
Complete Physical Examination ◽  
Polymerase Chain ◽  
High Index Of Suspicion ◽  
Immunocompetent Adults

ABSTRACTMeningitis caused by varicella zoster virus (VZV) is quite rare among young immunocompetent adults though immunocompromised patients are often seen to be affected by reactivation of VZV presenting with primary clinical features of dermatomal rashes and neurological sequelae. Here, we report the clinical scenario of a young, healthy male who had presented with fever, headache, and onset of dermatomal rashes later than the fever and was eventually diagnosed to be a case of VZV meningitis. We would like to highlight the fact that even young immunocompetent patients though rarely, might contract VZV meningitis and clinicians should have a high index of suspicion and keen eyes to catch the more obvious features of VZV infection on complete physical examination and must not harbor any reservations in ordering polymerase chain reaction for VZV DNA or initiating aggressive antiviral therapy.

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