Type IV Hypersensitivity Reaction to Dermabond (2-Octyl Cyanoacrylate) in Plastic Surgical Patients: A Retrospective Study

2021 ◽  
pp. 229255032110154
Author(s):  
Nawaf Naif Alotaibi ◽  
Tawheed Ahmad ◽  
Sari Monzer Rabah ◽  
Mohammad Tafazul Sheikh
Keyword(s):  
Cohort Study ◽  
Retrospective Study ◽  
Contact Dermatitis ◽  
Hypersensitivity Reaction ◽  
Retrospective Cohort ◽  
Reduction Mammoplasty ◽  
Surgical Patients ◽  
Type Iv ◽  
Post Operative Period ◽  
Trade Name

Background: The Dermabond (2-octyl cyanoacrylate) is a commonly used skin adhesive in plastic surgery. There are some reports in the literature regarding Dermabond associated contact dermatitis. In this retrospective cohort study, we evaluated the incidence and characteristics of contact dermatitis (type IV hypersensitivity reaction) post application of Dermabond (Trade name PRINEO manufactured by ETHICON) in patients who underwent plastic surgical breast procedures in our hospital. Methods: Sixty patients had undergone plastic surgical breast procedures (mastopexy and reduction mammoplasty) with Dermabond application over the period of last 3 years in our hospital. The records of these 60 patients were studied retrospectively. Results: Four patients (6.6%) out of the 60 patients taken for study had developed type IV hypersensitivity reaction to Dermabond. All of these patients presented with pruritus and skin rash in the second week of their post-operative period and none of them had any known past allergic history. Conclusion: We conclude that the incidence of type IV hypersensitivity allergic reaction post application of Dermabond (2-octyl cyanoacrylate) is significantly high and its possibility should be explained to the patients prior to its application.

scholarly journals Contact Dermatitis in Tertiary Hospital: A 2-year Retrospective Study

2021 ◽  
Vol 33 (2) ◽  
pp. 88
Author(s):  
Efenina Ginting ◽  
Damayanti Damayanti ◽  
Deasy Fetarayani ◽  
Afif Nurul Hidayati
Keyword(s):  
Food Allergy ◽  
Retrospective Study ◽  
Contact Dermatitis ◽  
Skin Disease ◽  
Clinical Presentation ◽  
Health Impact ◽  
Tertiary Hospital ◽  
Type Iv ◽  
Common Skin ◽  
Allergic Contact

Background: Contact dermatitis (CD) is a skin inflammatory caused by allergen or irritant that generates public health impact. CD is classified into two types, based on its etiological perspective, namely allergic contact dermatitis (ACD) due to a hypersensitivity type IV reaction and irritant contact dermatitis (ICD), which is a non-immunological reaction. Purpose: To determine the profile of CD patients at Dermatology and Venereology Outpatients Unit of Dr. Soetomo General Academic Hospital Surabaya in January 2018 – December 2019. Methods: A retrospective study by observation and recording data. The results of the data recap were then processed using Microsoft Excel to obtain conclusions.  Result: The results obtained were ACD (61.9%) and ICD (38.1%), aged 26-45 years (32.7%), female (79.3%). The most frequent occupation was housewives (25.3%), followed by private employees (24.5%). The most suspected causative substance was cosmetic (47.7%). The most common skin disease history was food allergy (11%), followed by drug allergy (2.8%), and atopic dermatitis (2.3%). The most frequent manifestation was acute (69.8%), with the most clinical presentation was erythematous macules (35%). Most therapies were given in combination (73.6%), with antihistamines (61%) and topical corticosteroids (49.2%) were the most prescription drug. Conclusion: ACD was more common than ICD, mostly in a female, dominated in the 26-45 years old. Housewife was the most occupational. Cosmetic was the most suspected causative substance. Food allergy was the most skin disease history. Acute was the most frequent manifestation. Erythematous macules were the most clinical presentation. Antihistamine and corticosteroid are the most common drug in combination therapy.

Flap Survival of Skin-Sparing Mastectomy Type IV: A Retrospective Cohort Study of 75 Consecutive Cases

2012 ◽  
Vol 20 (3) ◽  
pp. 981-989 ◽  
Author(s):  
Fabio Santanelli ◽  
Benedetto Longo ◽  
Michail Sorotos ◽  
Alessio Farcomeni ◽  
Guido Paolini
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Flap Survival ◽  
Type Iv

scholarly journals Dropout predictors at gyms: a retrospective study

2021 ◽  
Vol 43 ◽  
Author(s):  
Gledson Tavares Amorim Oliveira ◽  
Lucas Camilo Pereira ◽  
Maristela Linhares ◽  
Lídia Reniê Fernandes da Silva ◽  
Paulo Ricardo Silva ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Retrospective Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Adherence Rate ◽  
Factors Associated ◽  
Training Frequency ◽  
Contract Length ◽  
Dropout Predictors

ABSTRACT This study aimed to verify the risk factors associated with gym regulars’ dropout over 12 months. This is an observational, retrospective, cohort study. The sample consisted of two gyms (Gym 1: n=2027, age=39.1 ±13.1 years; Gym 2: n=1775, age=36.8 ±11.6 years). Each participant was followed up for 12 months, or until dropout, by controlling the biometric entry system using a turnstile. The adherence rate was of 11% at Gym 1 and 19% at Gym 2. At both gyms, training frequency ≤3x/month and 4-6x/month was associated with dropout. At gym 1, being a female, aged ≥43 years, and enrollment between October and December were dropout predictors. At Gym 2, dropout was associated with contract length ≤31 days and 32-186 days and enrollment between April and December.

scholarly journals Trends in Prevalence of Thyroid Cancer Over Three Decades: A Retrospective Cohort Study of 17,526 Surgical Patients

2015 ◽  
Vol 40 (3) ◽  
pp. 538-544 ◽  
Author(s):  
Aleksander Konturek ◽  
Marcin Barczyński ◽  
Małgorzata Stopa ◽  
Wojciech Nowak
Keyword(s):  
Cohort Study ◽  
Thyroid Cancer ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Surgical Patients

scholarly journals Rate of venous thromboembolism among surgical patients in Australian hospitals: a multicentre retrospective cohort study

BMJ Open ◽  
2014 ◽  
Vol 4 (10) ◽  
pp. e005502 ◽  
Author(s):  
Hassan Assareh ◽  
Jack Chen ◽  
Lixin Ou ◽  
Stephanie J Hollis ◽  
Kenneth Hillman ◽  
...  
Keyword(s):  
Cohort Study ◽  
Venous Thromboembolism ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Peer Groups ◽  
Care Facility ◽  
Public Hospitals ◽  
Surgical Patients ◽  
Targeted Interventions ◽  
Hospital Variation

ObjectivesDespite the burden of venous thromboembolism (VTE) among surgical patients on health systems in Australia, data on VTE incidence and its variation within Australia are lacking. We aim to explore VTE and subsequent mortality rates, trends and variations across Australian acute public hospitals.SettingA large retrospective cohort study using all elective surgical patients in 82 acute public hospitals during 2002–2009 in New South Wales, Australia.ParticipantsPatients underwent elective surgery within 2 days of admission, aged between 18 and 90 years, and who were not transferred to another acute care facility; 4 362 624 patients were included.Outcome measuresVTE incidents were identified by secondary diagnostic codes. Poisson mixed models were used to derive adjusted incidence rates and rate ratios (IRR).Results2/1000 patients developed postoperative VTE. VTE increased by 30% (IRR=1.30, CI 1.19 to 1.42) over the study period. Differences in the VTE rates, trends between hospital peer groups and between hospitals with the highest and those with the lowest rates were significant (between-hospital variation). Smaller hospitals, accommodated in two peer groups, had the lowest overall VTE rates (IRR=0.56:0.33 to 0.95; IRR=0.37:0.23 to 0.61) and exhibited a greater increase (64% and 237% vs 19%) overtime and greater between-hospital variations compared to larger hospitals (IRR=8.64:6.23 to 11.98; IRR=8.92:5.49 to 14.49 vs IRR=3.70:3.32 to 4.12). Mortality among patients with postoperative VTE was 8% and remained stable overtime. No differences in post-VTE death rates and trends were seen between hospital groups; however, larger hospitals exhibited less between-hospital variations (IRR=1.78:1.30 to 2.44) compared to small hospitals (IRR>23). Hospitals performed differently in prevention versus treatment of postoperative VTE.ConclusionsVTE incidence is increasing and there is large variation between-hospital and within-hospital peer groups suggesting a varied compliance with VTE preventative strategies and the potential for targeted interventions and quality improvement opportunities.

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