scholarly journals Errata

2017 ◽  
Vol 1 (5) ◽  
pp. 352-353
Keyword(s):  
Informed Consent ◽  
Silicone Oil ◽  
Neuronal Ceroid Lipofuscinosis ◽  
Case Series ◽  
Intravitreal Bevacizumab ◽  
Healthy Children ◽  
Retrospective Case ◽  
Posterior Scleritis ◽  
Ethical Approval ◽  
Written Informed Consent

An Ethical Approval Statement and/or Statement of Informed Consent should have been included for the articles listed below. Their corresponding statements are presented following the article information: Emerson GG, Kim JE, Packo KH, Flynn HW Jr. Guidelines for intraoperative time-out before corneal scraping and before fluid–air exchange. J Vitreoretin Dis. 2017;1(1):79-80. (Original DOI: 10.1177/2474126416680932) Ethical Approval: Ethical approval was not sought for the present study because no identifiable images or information were used and because this was a special correspondence. Statement of Informed Consent: Informed consent was not sought for the present study because no identifiable images were used. Ryder SJ, Tutiven JL, Gayer S, Miller D, Flynn HW Jr, Townsend JH. Retinal detachment repair in a patient with active Zika virus infection. J Vitreoretin Dis. 2017;1(1):81-83. (Original DOI: 10.1177/2474126416685495) Statement of Informed Consent: Informed consent was not sought for this case report because no identifiable images were used. Dubey N, Minija CK, Shanmugam MP. Intravitreal dexamethasone implant in a case of recurrent posterior scleritis. J Vitreoretin Dis. 2017;1(1):84-87. (Original DOI: 10.1177/2474126416681324) Statement of Informed Consent: Written informed consent was obtained from the patient to perform the procedure and have photographs taken. Kim H, Wang A, Mititelu M. Case series of anti-vascular endothelial growth factor and photodynamic therapy in the treatment of circumscribed choroidal hemangiomas. J Vitreoretin Dis. 2017;1(2):133-137. (Original DOI: 10.1177/2474126416687424) Statement of Informed Consent: Informed consent was not sought for the present study because no identifiable images were used. Cunningham WJ, Michael E, Welch S, Crosby N, Host B, Polkinghorne P. The Auckland Endophthalmitis Study: the incidence and management of endophthalmitis following intravitreal bevacizumab. J Vitreoretin Dis. 2017;1(3):175-180. (Original DOI: 10.1177/2474126417690987) Ethical Approval: Ethical approval for this study was waived by the Health and Disabilities Ethics Committees of New Zealand because the details of our study were such that ethics approval was not required. Statement of Informed Consent: Not applicable. Lee AC, Opremcak EM, Hunt C, et al. Severe corneal complications associated with corneal lubricant used during surgery. J Vitreoretin Dis. 2017;1(3):187-190. (Original DOI: 10.1177/2474126417698880) Ethical Approval: Ethical approval was not sought for the present study because it was a retrospective report and no identifiable data were included in the study. Statement of Informed Consent: Informed consent was not sought for the present study images because no identifiable images were used. Chen Y, Shah V, Jeroudi AM, Blinder KJ, Shah GK. Surgical detachment of the anterior hyaloid membrane from the posterior lens capsule: two techniques. J Vitreoretin Dis. 2017;1(3):214-217. (Original DOI: 10.1177/2474126417698873) Statement of Informed Consent: Informed consent was not sought for the present study because no identifiable images or data were used. Yau GL, Chin EK, Parke DW III, Bennett SR, Almeida DRP. West Nile virus chorioretinitis with foveal involvement: evolution of lesions on optical coherence tomography. J Vitreoretin Dis. 2017;1(3):218-221. (Original DOI: 10.1177/2474126417697593) Statement of Informed Consent: Informed consent was not sought for the present study because no identifiable images were used. Rahman R, Khan K, Stephenson J, Amjad M. Nonposturing surgery for persistent macular hole using heavy silicone oil (Oxane HD) endotamponade. J Vitreoretin Dis. 2017;1(4):246-250. (Original DOI: 10.1177/2474126417712645) Ethical Approval: Ethical approval was not sought for the present study because of the following reasons: The basis for this decision was made on the fact that there would be no change to the standard of care for patients studied and we were evaluating our service for failed macular holes treatment offered to patients. Statement of Informed Consent: Informed consent was not sought for the present study because it was not required as no identifiable images were used. Sundy M, Malihi M, Chang EY, et al. Retinal artery occlusions in healthy children. J Vitreoretin Dis. 2017;1(4):257-260. (Original DOI: 10.1177/2474126417710138) Statement of Informed Consent: Informed consent was not obtained for this multicenter retrospective case series because no identifiable images were used. Oellers P, Eliott D. Good visual outcome following vitrectomy for epiretinal membrane with foveal tissue herniation. J Vitreoretin Dis. 2017;1(4):278-280. (Original DOI: 10.1177/2474126417709382) Statement of Informed Consent: Informed consent was not sought for the present study because no identifiable images were used. Kovach JL. Persistent placoid maculopathy treatment response imaged with OCT angiography. J Vitreoretin Dis. 2017;1(4):281-283. (Original DOI: 10.1177/2474126417712646) Statement of Informed Consent: Informed consent was not sought for the present study because no identifiable images were used. Reyes-Capó D, Ventura CV, Tekin M, Lam BL, Berrocal AM. ABCA4 mutation in a patient with juvenile neuronal ceroid lipofuscinosis. J Vitreoretin Dis. 2017;1(4):284-286. (Original DOI: 10.1177/2474126417714136) Statement of Informed Consent: Written informed consent was obtained from the subject for the use of photographs for professional publication.

scholarly journals Cerliponase Alfa for the Treatment of Atypical Phenotypes of CLN2 Disease: A Retrospective Case Series

2020 ◽  
pp. 088307382097799
Author(s):  
Eva Wibbeler ◽  
Raymond Wang ◽  
Emily de los Reyes ◽  
Nicola Specchio ◽  
Paul Gissen ◽  
...  
Keyword(s):  
Treatment Duration ◽  
Chart Review ◽  
Rating Scale ◽  
Neuronal Ceroid Lipofuscinosis ◽  
Case Series ◽  
Language Function ◽  
Retrospective Case ◽  
Function Loss ◽  
Clinical Rating Scale

Background: The classic phenotype of CLN2 disease (neuronal ceroid lipofuscinosis type 2) typically manifests between ages 2 and 4 years with a predictable clinical course marked by epilepsy, language developmental delay, and rapid psychomotor decline. Atypical phenotypes exhibit variable time of onset, symptomatology, and/or progression. Intracerebroventricular-administered cerliponase alfa (rhTPP1 enzyme) has been shown to stabilize motor and language function loss in patients with classic CLN2 disease, but its impact on individuals with atypical phenotypes has not been described. Methods: A chart review was conducted of 14 patients (8 male, 6 female) with atypical CLN2 phenotypes who received cerliponase alfa. Pre- and posttreatment CLN2 Clinical Rating Scale Motor and Language (ML) domain scores were compared. Results: Median age at first presenting symptom was 5.9 years. First reported symptoms were language abnormalities (6 [43%] patients), seizures (4 [29%]), ataxia/language abnormalities (3 [21%]), and ataxia alone (1 [7%]). Median age at diagnosis was 10.8 years. ML score declined before treatment in 13 (93%) patients. Median age at treatment initiation was 11.7 years; treatment duration ranged from 11 to 58 months. From treatment start, ML score remained stable in 11 patients (treatment duration 11-43 months), improved 1 point in 1 patient after 13 months, and declined 1 point in 2 patients after 15 and 58 months, respectively. There were 13 device-related infections in 8 patients (57%) and 10 hypersensitivity reactions in 6 (43%). Conclusions: Cerliponase alfa is well tolerated and has the potential to stabilize motor and language function in patients with atypical phenotypes of CLN2 disease.

scholarly journals Medical terminology circulation and interactional organisation in interpreter-mediated medical encounters

2021 ◽  
Vol 11 ◽  
Author(s):  
Sara Pittarello
Keyword(s):  
Informed Consent ◽  
Active Participation ◽  
Point Of View ◽  
Personal Interest ◽  
Medical Terminology ◽  
Institutional Talk ◽  
Italian Hospital ◽  
Ethical Approval ◽  
Medical Interpreters ◽  
Written Informed Consent

Two medical encounters taking place in a Northern Italian hospital are analysed in this paper from a qualitative point of view, based on the author’s previous research. The aim is to reveal the strategies adopted by medical interpreters, in these two specific cases, to translate medical terminology and promote/exclude interlocutors’ active participation. This latter aspect is influenced by the way the interaction is socially and linguistically organised and, in particular, by how interlocutors’ utterances are translated. The prevalence of dyadic or triadic sequences and especially the shifts between such communication exchanges are pivotal in fostering or hindering interlocutors’ participation. Furthermore, medical interactions, as a form of institutional talk, enshrine specific expectations, which are mainly of a cognitive nature but may also be affective, as in the two encounters observed. By conveying such expectations and expressions of personal interest, interpreters have proved to contribute to the fair distribution of active participation among primary interlocutors. Hospital ethical approval and subjects’ written informed consent have been obtained.

Fluorescein Angiography of Persistent Incomplete Vascularization of the Retina After Bevacizumab Therapy in Retinopathy of Prematurity

2019 ◽  
Vol 3 (5) ◽  
pp. 304-308 ◽  
Author(s):  
Xihui Lin ◽  
Sagar B. Patel ◽  
Alice Y. Zhang ◽  
Daniel A. Brill ◽  
Kim H. Le ◽  
...  
Keyword(s):  
Fluorescein Angiography ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Case Series ◽  
Intravitreal Bevacizumab ◽  
Peripheral Retina ◽  
Medical Systems ◽  
Retrospective Case ◽  
Type 1 Rop

Purpose: This study evaluates the vascular development of premature infants at 50 weeks postconception after treatment with intravitreal bevacizumab for type 1 retinopathy of prematurity (ROP). Methods: A retrospective case series was conducted on type 1 ROP neonates with a high risk of general anesthesia complications. Patients were treated with bevacizumab between February 2013 and February 2016. At 50 weeks’ gestational age, all patients were imaged with RetCam (Clarity Medical Systems, Inc) fundus photographs and widefield fluorescein angiography (FA). Results: There were 4 boys and 7 girls with an average gestational age of 24.8 weeks and weight of 734.3 grams at birth. The estimated gestational age at injection was 37.1 weeks. Examination under anesthesia with FA was performed at a mean of 61 weeks posttreatment. Nineteen of 20 eyes (95%) of 11 infants had incomplete vascularization and peripheral nonperfusion on imaging. FA showed new vessels with increased tortuosity, microvascular abnormalities, and leakage past the original ridge. These 19 patients were treated with confluent ablative photocoagulation to the peripheral nonperfused retina. Patients were followed for a mean of 73.3 weeks after birth. None required incisional surgery. Conclusions: Patients with type 1 ROP treated with bevacizumab may have delayed vascularization of the peripheral retina and even late recurrence of active disease. Clinicians should regularly monitor patients after bevacizumab for potential neovascular complications.

scholarly journals Outcomes of 25-Gauge Vitrectomy With Relaxing Retinectomy for Retinal Detachment Secondary to Proliferative Vitreoretinopathy

2019 ◽  
Vol 3 (2) ◽  
pp. 69-75
Author(s):  
Yi Jiang ◽  
Daniel J. Oh ◽  
Wyatt Messenger ◽  
Jennifer I. Lim
Keyword(s):  
Visual Acuity ◽  
Retinal Detachment ◽  
Proliferative Vitreoretinopathy ◽  
Silicone Oil ◽  
Case Series ◽  
High Rate ◽  
Retrospective Case ◽  
Institutional Review ◽  
25 Gauge Vitrectomy

Purpose: The aim of this study is to evaluate visual and anatomic outcomes of 25-gauge vitrectomy with relaxing retinectomies for complex retinal detachment (RD) secondary to proliferative vitreoretinopathy (PVR). Methods: A single-center, retrospective case series of 44 patients who had undergone a 25-gauge vitrectomy with a relaxing retinectomy for the treatment of combined RD and PVR was performed. Preoperative characteristics, intraoperative techniques, and outcomes were analyzed. The rates of attachment, complications, and visual acuity were analyzed. Institutional review board/ethics committee approval was obtained, and the described research adhered to the tenets of the Declaration of Helsinki. Results: At the final follow-up, 27 eyes (61%) had attachment after 1 surgery, 41 eyes (93%) ultimately had attached retinas, 3 eyes (7%) had hypotony, 3 eyes had become phthisical (7%), and 24 eyes (56%) had improved visual acuity. After stratifying by visual outcomes, 20/400 or better best-corrected visual acuity was not associated with age ( P = .66), RD etiology ( P = .61), preoperative hypotony ( P = .60), nor size of retinectomy ( P = .48). Patients achieving 20/400 vision or better were statistically more likely to be pseudophakic ( P = .024) and have silicone oil removal ( P < .0001). Conclusion: The use of 25-gauge vitrectomy and relaxing retinectomy provides a high rate of reattachment and improved visual acuity.

scholarly journals Compassion fatigue as bruises in the soul: A qualitative study on nurses

2021 ◽  
pp. 096973302110032
Author(s):  
Tove Gustafsson ◽  
Jessica Hemberg
Keyword(s):  
Content Analysis ◽  
Informed Consent ◽  
Compassion Fatigue ◽  
Ethics Committee ◽  
Private Person ◽  
The Gift ◽  
Ethical Approval ◽  
Life Itself ◽  
The University ◽  
Written Informed Consent

Background: Nurses who are constantly being exposed to patients’ suffering can lead to compassion fatigue. There is a gap in the latest research regarding nurses’ experiences of compassion fatigue. Little is known about how compassion fatigue affects the nurse as a person, and indications of how it affects the profession are scarce. Aim: The aim of this study was to explore compassion fatigue experienced by nurses and how it affects them as persons and professionals. Research design, participants, and research context: A qualitative explorative approach was used. The data consisted of texts from interviews with seven nurses in various nursing contexts. Content analysis was used. Ethical consideration: Ethical approval was sought and granted from an ethics committee at the university where the researchers were based, and written, informed consent was obtained from all the participants. Findings: Five themes were discovered: Compassion as an empathic gift and compassion fatigue as a result of compassion overload, Compassion fatigue as exhausting the nurse as a professional and private person, Compassion fatigue as a crisis with potentially valuable insights, Compassion fatigue can be handled by self-care and focus on self, and Compassion fatigue is affected by life itself and multifaceted factors. Discussion: Compassion stress and overload can lead to compassion fatigue. Compassion fatigue affects the nurse’s ability to compassion, and the caring is no longer experienced in the same way; the nurses experienced it as being deprived of the gift of compassion. Compassion fatigue implicates a crisis with potentially valuable insights. Conclusion: Compassion fatigue can be symbolized as bruises in the soul, hurtful, but with time it can fade away, although it leaves a sense of caution within the nurse, which can affect the suffering patient.

scholarly journals Long-term results of intravitreal bevacizumab and dexamethasone for the treatment of punctate inner choroidopathy associated with choroidal neovascularization: A case series

2018 ◽  
Vol 6 ◽  
pp. 2050313X1877247
Author(s):  
Konstantinos T Tsaousis ◽  
Mohamed Nassr ◽  
Bharat Kapoor ◽  
Vasileios E Konidaris ◽  
Straton Tyradellis ◽  
...  
Keyword(s):  
Case Series ◽  
Intravitreal Bevacizumab ◽  
Intravitreal Injections ◽  
Long Term Results ◽  
Choroidal Neovascular Membrane ◽  
Retrospective Case ◽  
Early Therapy ◽  
Punctate Inner Choroidopathy ◽  
Female Patients ◽  
Intravitreal Dexamethasone

Introduction: To present a case series of three female patients with punctate inner choroidopathy. We report the outcomes after an essentially long follow-up period of up to 14 years and provide evidence of the effectiveness of intravitreal injections of bevacizumab and dexamethasone 0.7 mg in punctate inner choroidopathy patients with choroidal neovascular membrane formation. Case series presentation: This is a retrospective case series of three female patients with punctate inner choroidopathy who were treated with intravitreal injections anti-vascular endothelial growth factor agent (bevacizumab, 1.25 mg/0.05 mL). Two patients also received intravitreal dexamethasone 0.7 mg. Once a choroidal neovascular membrane developed, the outcome was poor with a best-corrected visual acuity of 6/60 or counting fingers in the affected eyes. The patients were followed up for 5, 14 and 8 years. Conclusion: The use of dexamethasone 0.7 mg in punctate inner choroidopathy yielded encouraging results and long periods of stability. When choroidal neovascular membrane complicates the primary disease, the prognosis is unfavourable, especially if the macula integrity has already been considerably affected. On the contrary, aggressive early therapy and continued monthly monitoring can prevent severe fibrosis, as showed in previous reports. Further larger-scale studies are needed to evaluate the efficacy of intravitreal dexamethasone 0.7 mg and bevacizumab as an alternative treatment in non-infectious uveitis.

scholarly journals Long-Term Observation of Triplex Surgery for Cataract after Phakic 6H Implantation for Super High Myopia

2016 ◽  
Vol 2016 ◽  
pp. 1-10
Author(s):  
Xin Liu ◽  
Fan Fan ◽  
Xiaoying Wang ◽  
Yi Lu ◽  
Tianyu Zheng ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
High Myopia ◽  
Silicone Oil ◽  
Case Series ◽  
Cell Loss ◽  
Retrospective Case ◽  
The Mean ◽  
Long Term Observation

Purpose. To analyze the safety, effectiveness, and stability of triplex surgery for phakic 6H anterior chamber phakic intraocular lens explantation and phacoemulsification with in-the-bag IOL implantation for super high myopia in long-term observations.Methods. This retrospective case series evaluated 16 eyes of 10 patients who underwent triplex surgery. Best corrected visual acuity (BCVA), endothelial cell density (ECD), and associated adverse events were evaluated.Results. The mean follow-up time after the triplex surgery was 46 ± 14 months. The mean logMAR BCVA was significantly improved after triplex surgery (P= 0.047). One eye developed endophthalmitis five days postoperatively and underwent pars plana vitrectomy (PPV). Five eyes with preoperative severe endothelial cell loss developed corneal decompensation and underwent keratoplasty at a mean time of 9.4 ± 2.6 months after the triplex surgery. One eye had graft failure and underwent a second keratoplasty. The eye developed rhegmatogenous retinal detachment and underwent PPV with silicone oil 18 months later. ECD before the triplex surgery was not significantly different compared with that at last follow-up (P= 0.495) apart from these five eyes. Three eyes (18.8%) developed posterior capsule opacification.Conclusions. Triplex surgery was safe and effective for phakic 6H related complicated cataracts. Early extraction before severe ECD loss is recommended.

scholarly journals Ahmed Glaucoma Valves versus EX-PRESS Devices in Glaucoma Secondary to Silicone Oil Emulsification

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Zhuyun Qian ◽  
Kai Xu ◽  
Xiangmei Kong ◽  
Huan Xu
Keyword(s):  
Success Rate ◽  
Silicone Oil ◽  
Case Series ◽  
Clinical Effects ◽  
Retrospective Case ◽  
Case Series Study ◽  
The Difference ◽  
Series Study ◽  
Glaucoma Implants

Objective. To evaluate and compare the clinical effects of Ahmed glaucoma valves (AGVs) and EX-PRESS implants on glaucoma secondary to silicone oil (SO) emulsification. Methods. A retrospective case-series study was designed. A total of 23 eyes with late intraocular pressure (IOP) elevation secondary to SO emulsification were included in the study. Antiglaucoma surgery with implantation of AGVs or EX-PRESS devices was performed. Pre- and postoperative ocular parameters were recorded at each visit during a 1-year follow-up period. The rates of complete success (IOP < 21 mmHg without medication) and qualified success (IOP < 21 mmHg with ≤3 glaucoma medications) were analyzed. Results. A total of 14 eyes underwent AGV implantation, and 9 underwent EX-PRESS implantation. The mean IOP and number of medications used at the last follow-up decreased significantly compared with that before surgery (P<0.001). The total success rate for all eyes including complete success (7/23) and qualified success (7/23) was 60.9% (14/23) at 1 year. The total success rate in the AGV group was 78.6% (11/14), whereas it was 33.3% (3/9) in the EX-PRESS group; the difference between the 2 groups was significant (P<0.05). Conclusion. For glaucoma secondary to SO emulsification, glaucoma implants could be effective at lowering IOP, and AGVs might produce better outcomes than EX-PRESS devices.

scholarly journals On mediating agents’ moves and how they might affect patient-centredness in mediated medical consultations

2021 ◽  
Vol 11 ◽  
Author(s):  
Demi K. Krystallidou
Keyword(s):  
Informed Consent ◽  
Translation Studies ◽  
Urban Hospital ◽  
Verbal Cues ◽  
Medical Encounter ◽  
Video Recordings ◽  
Medical Consultations ◽  
Ethical Approval ◽  
Written Informed Consent ◽  
Patient Centredness

The present study aims to shed some light on indicators that might potentially challenge patient-centredness (as practised by self-professed patient-centred doctors) within a mediated medical encounter, and to contribute to the fields of linguistics, translation studies and medical communication. Selected instances of transcribed video recordings are analysed within the framework of Goffman’s footing and participation roles, while transcribed audio recorded interviews with participants in the triad are taken into consideration as well. Both verbal and non-verbal cues (i.e., gaze) are taken into account. The data is drawn from a corpus of video-recorded mediated consultations in a urban hospital in Belgium. Hospital ethical approval and subjects’ written informed consent have been obtained

The patients have a story to tell: Informed consent for people who use illicit opiates

2020 ◽  
Vol 27 (3) ◽  
pp. 666-672
Author(s):  
Jane McCall ◽  
J Craig Phillips ◽  
Andrew Estafan ◽  
Vera Caine
Keyword(s):  
Cognitive Impairment ◽  
Informed Consent ◽  
Social Workers ◽  
Thematic Analysis ◽  
Descriptive Study ◽  
Ethical Considerations ◽  
Opiate Use ◽  
Ethical Approval ◽  
The University ◽  
Written Informed Consent

Background: There is a significant discourse in the literature that opines that people who use illicit opiates are unable to provide informed consent due to withdrawal symptoms and cognitive impairment as a result of opiate use. Aims: This paper discusses the issues related to informed consent for this population. Ethical considerations: Ethical approval was obtained from both the local REB and the university. Written informed consent was obtained from all participants. Method: This was a qualitative interpretive descriptive study. 22 participants were interviewed, including 18 nurses, 2 social workers and 2 clinic support workers. The findings were analyzed using thematic analysis, which is a way of systematically reducing the complexity of the information to arrive at generalized explanations. Results: The staff at the clinic were overwhelming clear in their judgment that people who use opiates can and should be able to participate in research and that their drug use is not a barrier to informed consent. Conclusions: It is important to involve people who use opiates in research. Protectionist concerns about this population may be overstated. Such concerns do not promote the interests of research participants. People who use heroin need to be able to tell their story.

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