Prospective analysis of risk factors associated with group B streptococcal colonisation in neonates born at a tertiary care centre in India

Retinopathy of prematurity is one of the commonest cause of blindness in sick neonates exposed to excessive oxygen following NICU admissions. The present study was thus conducted to assess the pattern and risk factors associated with incidence of retinopathy of prematurity.A retrospective record based study was conducted at tertiary care centre between 1st July 2017 to 30thMay 2020 were screened for ROP. Baseline characteristics and risk factors for ROP were assessed. The zone and stage of ROP were categorized as per the International classification of ROP along with iris neovascularisation and plus disease as per the revised international classification of retinopathy of prematurity (ICROP) preplus disease criteria. Data was entered in excel sheet and analysed using SPSS software version 20.Majority of neonates belonged to gestational age of 28 to 31 weeks (58.8%) and 51.2% neonates had birthweight of 1.5 to 2 kg. Male preponderance was observed with male: female ratio of 1.75:1. Amongst the various risk factors, the occurrence of ROP was highly significantly associated with gestational age and birthweight (p<0.01). Subgroup analysis revealed that aggressive posterior ROP (APROP) contributed significantly to Type I ROP in 11.1% (3) cases. And the observed difference in gestational age and birthweight between APROP and other cases of ROP were statistically highly significant (p<0.01).Early and timely screening of ROP for all high risk neonates especially low birth weight and neonates with small gestational age should be mandatory as these are the most significant risk factors associated with ROP in present study.

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An Evaluation of Antibiotic Profile, Molecular Characterisation and Risk Factors Associated with Carbapenem Resistant Non Fermentative Gram Negative Isolates in a Tertiary Care Centre

International Journal of Current Microbiology and Applied Sciences ◽

10.20546/ijcmas.2017.605.115 ◽

2017 ◽

Vol 6 (5) ◽

pp. 1057-1066

Author(s):

N. Grover ◽

N.K. Das ◽

M. Kumar ◽

R. Sriram ◽

V.L. Dudhat ◽

...

Keyword(s):

Risk Factors ◽

Tertiary Care ◽

Molecular Characterisation ◽

Care Centre ◽

Tertiary Care Centre ◽

Gram Negative ◽

Factors Associated ◽

Carbapenem Resistant

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Prevalence and risk factors associated with primary open angle glaucoma in diabetic patients in a tertiary care centre

International Journal of Medical Ophthalmology ◽

10.33545/26638266.2021.v3.i1a.51 ◽

2021 ◽

Vol 3 (1) ◽

pp. 01-04

Author(s):

N Rajendran ◽

I Anesha Isaac ◽

Janie Salor ◽

J Kishore Kumar Jacob

Keyword(s):

Risk Factors ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

Tertiary Care ◽

Diabetic Patients ◽

Open Angle ◽

Care Centre ◽

Tertiary Care Centre ◽

Factors Associated

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Effectiveness of bundled interventions in reducing surgical site infections in elective caesarean sections and caesarean hysterectomies in a tertiary care centre

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20202716 ◽

2020 ◽

Vol 9 (7) ◽

pp. 2823

Author(s):

Gunjan Yadav ◽

Kalpana Yadav ◽

Parasuram Waddar

Keyword(s):

Risk Factors ◽

Treatment Outcomes ◽

Tertiary Care ◽

Intervention Group ◽

Surgical Site Infections ◽

Routine Care ◽

Care Group ◽

Care Centre ◽

Tertiary Care Centre ◽

Factors Associated

Background: Surgical site infections are the most common and easily preventable infections complicating surgeries. CDC recommends certain bundle interventions for the prevention of SSIs. Hence the present study was undertaken to see the effectiveness and feasibility of the bundle interventions in the elective caesarean sections and caesarean hysterectomies.Methods: A total of 600 patients were taken. Bundled interventions were applied in 278 caesarean sections and 26 caesarean hysterectomies. Routine care was implemented in 262 caesarean sections and 34 caesarean hysterectomies. Rate of SSI, risk factors associated and treatment outcomes were studied.Results: 8 out of 304 cases of the bundled intervention group developed SSI, giving a rate of 2.6%. 52 cases out of 296 in the routine care group developed SSI, the SSI rate being 17.5%. Anemia and diabetes were the most common risk factors.Conclusions: Adherence to bundled interventions can significantly and easily reduce the incidence of SSI.

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Clinicosociodemographic profile of ruptured ectopic pregnancies at a tertiary care centre

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20171942 ◽

2017 ◽

Vol 6 (5) ◽

pp. 1885

Author(s):

Soumya Ranjan Panda ◽

Anjali Rani ◽

Mahendra Meena

Keyword(s):

Risk Factors ◽

Socioeconomic Status ◽

Ectopic Pregnancy ◽

Tertiary Care ◽

Care Centre ◽

Tertiary Care Centre ◽

Factors Associated ◽

Number Of Patients ◽

History Of ◽

Ectopic Pregnancies

Background: Rupture of an ectopic pregnancy remains the most dreaded complication of a pregnancy related event and is the commonest cause of maternal mortality in the first trimester of pregnancy. In the developing countries, the maternal death rate among patients admitted with ectopic pregnancy was found to be as high as one in ten. In addition to high risk for mortality, rupture of an ectopic pregnancy could affect future fertility of a woman. The objectives of this study are to analyse the sociodemographic and clinical characteristics and find out the incidence rate and risk factors associated with ruptured ectopic pregnancies in a tertiary care institution.Methods: This is a retrospective study and was conducted over a period of one year from September 2015 to September 2016 in Department of Obstetrics and Gynecology at Institute of Medical Sciences, BHU, Varanasi, India. It is a tertiary care centre getting referrals not only from nearby cities and hospitals but also from major cities of neighbour states. During this time frame a total of 2601 deliveries have taken place and 57 cases of ruptured ectopic pregnancies were reported. Data were collected in a preconceived format.Results: Total numbers of vaginal deliveries were 2601 during the study period. Out of which 63 (2.42%) were found to be ectopic pregnancies and 57 (1.99%) were diagnosed as ruptured ectopic pregnancies. Maximum number of patients (70.17%) were between 21 and 30 years of age. As far as parity is concerned only 12.29 % of patients were primigravida where as 70.71% patients were multigravida. Previous history of pelvic inflammatory disease was associated among maximum number of cases i.e 50.87% of total number of cases. Among other risk factors, previous abortions, previous ectopic pregnancies and history of infertility treatment were the prime ones. Maximum number of patients were from lower and lower middle class socioeconomic status. Ampullary type of Tubal ectopic pregnancies were found to be the commonest ones. Two cornual pregnancies and two ovarian pregnancies were also found in this series. In 85.97 % of patients the amount of hemoperitoneum was found to be more than 500 ml.Conclusions: There is high incidence rate of ectopic pregnancy and low rate of diagnosis before rupture occurs in developing nations as in our scenario. Pelvic inflammatory disease, Maternal education, socioeconomic status, parity and history of subfertilty are the risk factors associated with ruptured ectopic pregnancy. Effective efforts should be taken to encourage the level of education and improve the rate of diagnosis among health care providers before the occurrence of rupture.

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Clinical profile and risk factors for mortality among COVID-19 inpatients at a tertiary care centre in Bengaluru, India

Monaldi Archives for Chest Disease ◽

10.4081/monaldi.2021.1724 ◽

2021 ◽

Author(s):

Yamini Marimuthu ◽

Radhika Kunnavil ◽

NS Anil ◽

Sharath Burugina Nagaraja ◽

N Satyanarayana ◽

...

Keyword(s):

Risk Factors ◽

South India ◽

Linear Models ◽

Tertiary Care ◽

Male Gender ◽

Clinical Profile ◽

Rank Test ◽

Care Hospital ◽

Care Centre ◽

Tertiary Care Centre

COVID-19 is an emerging viral disease affecting more than 200 countries worldwide and it present with varied clinical profile throughout the world. Without effective drugs to cure COVID-19, early identification and control of risk factors are important measures to combat COVID-19. This study was conducted to determine the clinical profile and risk factors associated with mortality among COVID-19 patients in a tertiary care hospital in South India. This record-based longitudinal study was conducted by reviewing the case records of COVID-19 patients admitted for treatment from June 2020 to September 2020 in a tertiary care centre in South India. The clinical details, discharge/death details, were collected and entered in MS Excel. Potential risk factors for COVID-19 mortality were analysed using univariate binomial logistic regression, generalized linear models (GLM) with Poisson distribution. Survival curves were made using the Kaplan-Meier method. Log-rank test was used to test the equality of survivor functions between the groups. Out of 854 COVID-19 patients, 56.6% were men and the mean (standard deviation) age was 45.3(17.2) years. The median survival time was significantly lesser in male COVID-19 patients (16 days) as compared to female patients (20 days). Increasing age, male gender, patients presenting with symptoms of fever, cough, breathlessness, smoking, alcohol consumption, comorbidities were significantly associated with mortality among COVID-19 patients. Patients with older age, male gender, breathlessness, fever, cough, smoking and alcohol and comorbidities need careful observation and early intervention. Public health campaigns aimed at reducing the prevalence of risk factors like diabetes, hypertension, smoking and alcohol use are also needed.

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