Clindamycin Release Determined by High Performance Liquid Chromatography from a Novel low-Cost Local Drug Delivery System: A New Potential Treatment Option for Chronic Osteomyelitis

2011 ◽  
Vol 23 (5) ◽  
pp. 282-284 ◽  
Author(s):  
D. Frank ◽  
G. Montskó ◽  
I. Juricskay ◽  
B. Borsiczky ◽  
G. Cseh ◽  
...  
Author(s):  
SK MANIRUL HAQUE ◽  
MURAD ALSAWALHA

Amlodipine is the best-prescribed medication for cardiovascular disease major risk factor for hypertension and atorvastatin well known for diabetic. First discussed low cost ultraviolet-visible technique for the determination and quantitation of drugs in pharmaceuticals and biological fluids. Chromatographic techniques have an application with respect to trace analysis. Different types of chromatography such as high-performance liquid chromatography, high performance thin layer chromatography have most frequent applications in the field of pharmaceutical as well as biomedical analyses. Chromatography combined with mass spectrophotometry has the ability to collect molecular ion, followed to prepare a spectrum to assess molecular weight as well as structure. High-performance liquid chromatography coupled with mass spectrophotometry is a reliable and dynamic technique for the analysis of small and large drugs molecule. The advantages and disadvantages of all techniques are compared with each other with respect to sensitivity, reproducibility and other important parameters. The investigation also focused for the quantitation on both drugs in pharmaceutical preparations and plasma samples with the help of all available analytical techniques.


2012 ◽  
Vol 578 ◽  
pp. 58-62
Author(s):  
Yong Shao ◽  
Hui Liu ◽  
Liang Wan

This study aimed to apply cinder supported CaO/KF particle catalyst in heterogeneous transesterification of soybean oil. In this system, a specially designed column reactor was used for the reaction. Eighty grams of catalyst were loaded and reaction temperature were set at 65°C. The effects of material flow rate and molar ratio of methanol to oil were investigated. High performance liquid chromatography (HPLC) results showed that at different conditions, the triglyceride (TG) conversion turning points kept around 82%. When flow rate was 3mL min-1, the maximum amount of biodiesel could be produced. Larger amount of biodiesel could be produced at lower methanol/oil molar ratio, but higher TG conversions were achieved at higher methanol/oil molar ratio. The leakage of K2O from the surface of catalyst was the main reason for the catalyst deactivity, the regular crystal forms of the catalyst material were changed after usage.


2015 ◽  
Vol 30 (9) ◽  
pp. 1927-1934 ◽  
Author(s):  
Lihuan Shen ◽  
Jiannan Sun ◽  
Heyong Cheng ◽  
Jinhua Liu ◽  
Zigang Xu ◽  
...  

This work demonstrates a low-cost and demountable nanoflow nebulizer with a small dead volume for stable introduction of liquids at nanoflow rates into ICP-MS.


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