scholarly journals The Clinical Significance of Erythrocyte Cholinesterase Titers

Blood ◽  
1955 ◽  
Vol 10 (11) ◽  
pp. 1132-1138 ◽  
Author(s):  
JEAN CAPTAIN SABINE
Keyword(s):  
Normal Distribution ◽  
Clinical Significance ◽  
Lower Limit ◽  
Whole Blood ◽  
Mean Value ◽  
Small Samples ◽  
Special Equipment ◽  
The Mean ◽  
Normal Adults

Abstract A method for determining erythrocyte cholinesterase titers on small samples of whole blood is described in detail. The method is one which requires little special equipment and can be used by any competent technician. Data for erythrocyte cholinesterase are presented on a group of 101 normal adults, and it is shown that the observed data fit the normal distribution. Eighteen children, aged three months to ten years, all had values within the adult distribution, and the mean value was the same as that for adults. Seven newborn babies all had values at or below the lower limit for adults.

The Excretion of Isotope in Urea and Ammonia for Estimating Protein Turnover in Man with [15N]Glycine

1981 ◽  
Vol 61 (2) ◽  
pp. 217-228 ◽  
Author(s):  
E. B. Fern ◽  
P. J. Garlick ◽  
Margaret A. McNurlan ◽  
J. C. Waterlow
Keyword(s):  
Protein Metabolism ◽  
Protein Turnover ◽  
Mean Value ◽  
Intravenous Dose ◽  
Whole Body ◽  
Body Protein ◽  
End Products ◽  
The Mean ◽  
15N Urea ◽  
Normal Adults

1. Four normal adults were given [15N]-glycine in a single dose either orally or intravenously. Rates of whole-body protein turnover were estimated from the excretion of 15N in ammonia and in urea during the following 9 h. The rate derived from urea took account of the [15N]urea retained in body water. 2. In postabsorptive subjects the rates of protein synthesis given by ammonia were equal to those from urea, when the isotope was given orally, but lower when an intravenous dose was given. 3. In subjects receiving equal portions of food every 2 h rates of synthesis calculated from ammonia were much lower than those from urea whether an oral or intravenous isotope was given. Comparison of rates obtained during the post-absorptive and absorptive periods indicated regulation by food intake primarily of synthesis when measurements were made on urea, but regulation primarily of breakdown when measurements were made on ammonia. 4. These inconsistencies suggest that changes in protein metabolism might be assessed better by correlating results given by different end-products, and it is suggested that the mean value given by urea and ammonia will be useful for this purpose.

scholarly journals True and Pseudo Cholinesterase levels in short and long-term of pesticides exposures

2020 ◽  
pp. 9-12
Author(s):  
Mohammed Abdul Rahman ◽  
Raghunatha Rao D ◽  
Vasantha L
Keyword(s):  
Whole Blood ◽  
Acute Poisoning ◽  
Mean Value ◽  
Serum Cholinesterase ◽  
Control Group ◽  
Study Group ◽  
Chronic Poisoning ◽  
The Mean ◽  
The Difference ◽  
And Control

The present study is aimed to study and analyze the true and pseudo Cholinesterase levels in the subjects exposed to pesticides during short term by intentional or accidental intake and long term exposure due to their occupation were studied at Department of Biochemistry, SVS medical college and hospital mahbubnagar district. Whole blood cholinesterase levels and Pseudo cholinesterase levels were estimated. 150 people were taken as controls who had no medical illness and a total number of 300 cases of pesticide poisoning were selected, aged between 20 to 55 years, which consist of 150 acute poisoning and 150 chronic poisoning subjects in Mahbubnagar district, were taken as case study, the detailed case history and the type of organophosphorus pesticide taken were recorded. Mean and standard deviation (S.D) of all variables were calculated and compared with those of controls. Statistical significance was assessed and P-value <0.05 were considered significant.           During acute poisoning the mean value of Whole blood cholinesterase/True cholinesterase (U / L) in acute poisoning cases on first day was 1.267± 0.612 on 3th day was 1.651±0.647, on 7th day was 2.221±0.684 and at the end of 6 months was 3.970±0.404.The difference between the study group and control group (4.0 ± 0.39) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in acute poisoning cases on first day was 2213.05 ± 1749.81, on 3th day was 2862.3 ± 2025.6, on 7th day was 4008.4 ± 2355.9 and at the end of 6 months was 7708.34 ± 880.72.The difference between the study group and control group (7991.97 ± 1276.5) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. During chronic poisoning (exposure) the mean value of Whole blood cholinesterase (U/L) in controls is 4.0 ± 0.39 as compared to 3.019 ± 0.848 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in controls was 7991.97 ± 1276.5 as compared to 6214 ± 1189 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant.

Lead Levels in Cord Blood

PEDIATRICS ◽  
1972 ◽  
Vol 49 (4) ◽  
pp. 606-608
Author(s):  
Paul Harris ◽  
Marshall R. Holley
Keyword(s):  
Cord Blood ◽  
Lead Poisoning ◽  
Whole Blood ◽  
Blood Lead ◽  
Mean Value ◽  
Diagnosis And Treatment ◽  
Normal Blood ◽  
Blood Lead Levels ◽  
Lead Levels ◽  
The Mean

Blood lead levels were determined on 24 mothers during labor and on the blood of their newborn offspring. The mean value for the mother's blood lead was 13.2 µg/100 gm (range 10 to 20) and for the cord blood 12.3 (range 10 to 20) µg/100 gm whole blood. These levels are lower than "normal" blood lead standards usually accepted in the diagnosis and treatment of childhood lead poisoning.

scholarly journals Neutral Saturated Lapse Rate: An Experimental Check from CALJET-1998 and PACJET-2001

2009 ◽  
Vol 137 (12) ◽  
pp. 4382-4385 ◽  
Author(s):  
Renzo Richiardone ◽  
Massimiliano Manfrin
Keyword(s):  
High Resolution ◽  
Normal Distribution ◽  
Mean Value ◽  
Lapse Rate ◽  
Temperature Profiles ◽  
Experimental Check ◽  
Rate Distribution ◽  
The Mean ◽  
Lapse Rates ◽  
Good Agreement

Abstract The lapse rates of high-resolution temperature profiles during nearly neutral, saturated conditions are compared with the saturated adiabatic lapse rate and with that proposed by Richiardone and Giusti. A good agreement between the latter and the mean value of the observed lapse rate is found, whereas the saturated adiabatic lapse rate differs significantly, confirming experimentally that it is not completely correct to assess the moist neutrality from a comparison with the saturated adiabatic lapse rate. The lapse-rate distribution supports the hypothesis that the lapse-rate statistics is a local collection of saturated adiabatic lapse rates in a background normal distribution centered around the neutrality.

scholarly journals Significance of Blood Cadmium Concentrations in Patients with Renal Disorders or Essential Hypertension and the Normal Population

1978 ◽  
Vol 15 (1-6) ◽  
pp. 197-200 ◽  
Author(s):  
Roberta J. Ward ◽  
Monica Fisher ◽  
Marisol Tellez-Yudilevich
Keyword(s):  
Essential Hypertension ◽  
Whole Blood ◽  
Normal Population ◽  
Cadmium Concentration ◽  
Normal Subjects ◽  
Mean Value ◽  
Renal Disorders ◽  
Control Subjects ◽  
Blood Cadmium ◽  
The Mean

Summary Cadmium concentrations in whole blood have been determined in normal control subjects, in patients with untreated essential hypertension or with treated essential hypertension, and in those with acute or chronic renal disorders. High cadmium concentrations were not found in the patients with untreated essential hypertension. Most tobacco smokers were found to have high blood cadmium concentrations. When the mean cadmium concentrations from each group of patients were compared with those of the control subjects no significant differences were found. When the four groups were divided into smokers and non-smokers, however, a significantly higher mean value was found for the non-smoking renal patients in comparison with the non-smoking normal subjects. The marked increases in blood cadmium concentration in the patients with renal disorders may be attributed to impaired excretion.

scholarly journals Erythroid marrow function in anemic patients

Blood ◽  
1987 ◽  
Vol 69 (1) ◽  
pp. 296-301 ◽  
Author(s):  
M Cazzola ◽  
P Pootrakul ◽  
HA Huebers ◽  
M Eng ◽  
J Eschbach ◽  
...  
Keyword(s):  
Aplastic Anemia ◽  
Whole Blood ◽  
Iron Uptake ◽  
Transferrin Saturation ◽  
Pure Red Cell Aplasia ◽  
Mean Value ◽  
Transfusion Therapy ◽  
Plasma Iron ◽  
The Mean ◽  
Marrow Activity

Abstract Erythropoietic activity is known to be closely associated with marrow iron uptake. A modification of the standard measure of plasma iron turnover has been developed in which erythron transferrin uptake (ETU) rather than iron uptake has been calculated. The ETU has the advantage of providing a parameter of erythroid marrow activity independent of change produced by plasma iron and transferrin saturation. Measurements in 80 patients with anemia were compared to the normal value of 60 +/- 12 mumol/L whole blood/d. The mean ETU for ten patients with severe aplastic anemia and for six patients with pure red-cell aplasia were 12 +/- 8 and 12 +/- 11 mumol/L whole blood/d, respectively. In ten transfusion-dependent patients with renal failure under dialysis therapy, the mean value was 35 +/- 11, while ten other dialyzed patients who were transfusion independent had a mean ETU of 73 +/- 21 mumol/L whole blood/d. Sixteen patients with hemolytic anemia had an average ETU of 400 +/- 130, while 28 patients with ineffective erythropoiesis had a mean value of 474 +/- 147 mumol/L whole blood/d. While patients with hypoproliferative anemia showed no relation between the severity of anemia and ETU, those with hyperproliferative erythroid marrow showed increasing values as the anemia became more severe. Sequential measurements in patients with aplastic anemia under treatment and in thalassemic patients under transfusion therapy showed the value of this measurement in monitoring the effects of treatment on erythroid marrow activity. It is concluded that the measurement of ETU provides a more direct ferrokinetic evaluation of erythroid activity in anemic states.

Estimation of the Mean Value for the Normal Distribution with Constraints on d-Risk

2018 ◽  
Vol 39 (3) ◽  
pp. 377-387 ◽  
Author(s):  
R. F. Salimov ◽  
Su-Fen Yang ◽  
E. A. Turilova ◽  
I. N. Volodin
Keyword(s):  
Normal Distribution ◽  
Mean Value ◽  
The Mean

scholarly journals Fluorometric Assay of Human Serum Carnosinase Activity in Normal Children, Adults and Patients with Myopathy

1984 ◽  
Vol 21 (6) ◽  
pp. 510-514 ◽  
Author(s):  
K Bando ◽  
T Shimotsuji ◽  
H Toyoshima ◽  
C Hayashi ◽  
K Miyai
Keyword(s):  
Muscular Dystrophy ◽  
Human Serum ◽  
Accurate Method ◽  
Mean Value ◽  
Adult Women ◽  
Normal Children ◽  
Adult Men ◽  
The Mean ◽  
Low Activity ◽  
Normal Adults

A sensitive, accurate method has been established for the assay of serum carnosinase by measuring the fluorescence emitted from the L-histidine liberated on treatment with o-phthaldialdehyde. Using this method the serum values for normal adults, infants and children were measured. The mean value was very low in infants of less than 1 year old but increased with age, being almost the same in children aged 6 years or more as in adults. In adult men, the mean activity was 1·85 μmol/mL/h and in adult women it was 2·07 μmol/mL/h. Low activity was observed in patients with muscular dystrophy.

Sign in / Sign up

Export Citation Format

Share Document