Complex treatment of widespread destructive pulmonary tuberculosis using innovative technology of the main bronchial stump treatment during pneumonectomy

Author(s):  
Genrik Asoyan ◽  
Mamed Bagirov ◽  
Svetlana Sadovnikova ◽  
Dmitry Prohodcov ◽  
Nina Nikitina ◽  
...  
2008 ◽  
Vol 5 ◽  
pp. S21-S22
Author(s):  
V.V. Kiryanova ◽  
T.I. Vinogradova ◽  
A.N. Levashov ◽  
T.B. Potepun

2020 ◽  
Vol 98 (1) ◽  
pp. 35-40
Author(s):  
O. Yu. Askalonova ◽  
E. A. Tseymakh ◽  
A. V. Levin ◽  
P. E. Zimonin

The objective of the study: to assess the efficacy of complex treatment with endobronchial valve implantation in the patients suffering from drug resistant fibrous cavernous pulmonary tuberculosis.Subjects and methods. Treatment outcomes in 97 patients with limited fibrous cavernous pulmonary tuberculosis were analyzed. Main Group included 42 patients who had bronchial valve block implanted. Comparison Group included 55 patients. Artificial pneumoperitoneum was used in both groups.Results. In Main Group, sputum conversion was achieved in 12 months in 40 (95.2%) patients, and in 32 patients (58.2%) in Comparison Group (p < 0.01). In 12 months after treatment start, positive X-ray changes were observed in 42 (100%) patients of Main Group and 40 (72.7%) patients of Comparison Group. Healing of cavities in 12 months was observed only in the patients from Main Group (26 (61.9%) patients). Upon completion of the study, surgery was still indicated to 4 (9.5%) of patients from Main Group and to 35 (63.6%) patients from Comparison Group.


2017 ◽  
Vol 2 ◽  
pp. 18-18 ◽  
Author(s):  
Piotr Yablonskii ◽  
Grigorii Kudriashov ◽  
Igor Vasilev ◽  
Armen Avetisyan ◽  
Olga Sokolova

2021 ◽  
Vol 19 (1) ◽  
pp. 36-39
Author(s):  
Yu. A. Sheifer ◽  
◽  
I. S. Gelberg ◽  

Background. In destructive forms of pulmonary tuberculosis, especially in the presence of drug resistance of mycobacteria, one of the ways to increase the effectiveness of therapy is the use of collapse therapeutic techniques in various modifications. Purpose of the study: to develop and substantiate an algorithm for complex treatment of destructive forms of pulmonary tuberculosis, using artificial pneumothorax (AP). Material and methods: A cohort of 84 people with destructive pulmonary tuberculosis was formed. It was divided into two groups: 42 patients in the main group (chemotherapy (ChT) + AP) and 42 in the comparison group (ChT). Results: an algorithm for the treatment of patients with destructive forms of pulmonary tuberculosis was formulated. Within a period of up to 6 months, abacillation was achieved in 61.9% of cases in the main group (MG), and in 18.9% (p <0.05) in the comparison group (CG). By the 10th month of treatment, the closure of decay cavities was achieved in 78.7% of cases in the MG and in 42.8% (p <0.05) in the CG. By 12 months the closure of decay cavities was observed in 92.1 and 52.4% of cases respectively (p <0.05). Conclusions: The use of the algorithm for the complex treatment of destructive forms of pulmonary tuberculosis makes it possible to achieve abacillation at an earlier time (up to 6 months - in 61.9%). It also allows to increase the frequency of cavity closure by 39.6% as well as achieve an increase in clinical cure (according to long-term results of treatment) by 23.8% and a decrease in the amplification of drug resistance and mortality by 14.3% and 11.9% correspondingly.


2019 ◽  
Vol 0 (2) ◽  
pp. 57-62
Author(s):  
O.V. Khmel ◽  
I.A. Kalabukha ◽  
V.Ye. Ivashchenko ◽  
Ye.M. Maietnyi ◽  
Ya.M. Voloshyn ◽  
...  

2021 ◽  
Vol 29 (4) ◽  
pp. 10-14
Author(s):  
O. I. Shpak ◽  
◽  
V. B. Bychkovskyi ◽  
O. B. Randiuk ◽  
M. S. Opanasenko ◽  
...  

O. I. Shpak, V. B. Bychkovskyi, O. B. Randiuk, M. S. Opanasenko, O. V. Tereshkovich, B. N. Konik, O. A. Gaidar, L. I. Levanda Аbstract Endoscopic bronchial valve blocking is a type of interventional bronchoscopy, which makes a therapeutic hypoventilation with the subsequent development of atelectasis in the affected area of the lung while maintaining the drainage function of the blocked bronchus and the cavity of destruction or closure of the bronchial defect by using an endobronchial valve. Aim: to evaluate the results valvular bronchial blocking in patients with chemo-resistant pulmonary tuberculosis (CRPTB) instead of surgical intervention or in the postoperative period. Materials and methods. 94 bronchial blockages were performed in patients with CRPTB. The patients were divided into three groups. Group I (36 patients) — a valve was placed during chemotherapy without surgical treatment. Group II (31 patients) — pyopneumothorax with destruction cavity discharge into the pleural cavity. Group III (27 patients) — volume reduction surgery(lobectomy, bilobectomy and pulmonectomy), complicated by the bronchial stump incompetency. Results. In group I favorable outcomes were observed in 27 cases (75,0 %). In patients with pneumothorax, complicated by empyema of the pleural cavity and bronchopulmonary fistula (group II) the favorable outcomes were achieved in 28 (90,3 %) patients. In postoperative patients, undergoing different volume reduction interventions (group III), favorable otcomes were registered in 23 (85,2 %) patients. Conclusion. Valvular bronchial blocking is highly effective method in the treatment of patients with CRPTB and certain complications (empyema of the pleural cavity with bronchopulmonary fistula, failure of the bronchial stump in the postoperative period), and in patients, who already underwent surgery, as well. Key words: chemo-resistant pulmonary tuberculosis, complications, bronchial valve blocking, surgical treatment.


2017 ◽  
Vol 98 (2) ◽  
pp. 194-199
Author(s):  
N A Lunina ◽  
O V Velikaya ◽  
V A Kunin

Aim. To study clinical efficacy of chronic generalized periodontitis treatment in patients with infiltrative pulmonary tuberculosis with the use of α-lipoic acid. Methods. 50 patients with chronic generalized periodontitis and infiltrative pulmonary tuberculosis randomly divided into 2 groups were examined. The study group included 25 patients who had received α-lipoic acid «Octolipen» in complex treatment for 3 months. The comparison group included 25 patients who were administered complex treatment of tuberculosis and periodontitis without α-lipoic acid. All patients on admission and dynamically after 3 months of treatment had routine clinical studies, cytology analysis of capillary gingival blood and gingival fluid and cytokine status testing of oral fluid. Results. Patients with chronic generalized periodontitis combined with infiltrative pulmonary tuberculosis who received «Octopilen» had statistically significant positive dynamics of clinical signs and decrease of basic dental indices after 3 months of treatment compared to baseline data. Dynamics of IL-1β, tumor necrosis factor α and IL-4 revealed significant decrease of these cytokines concentration in gingival fluid in patients from both groups after 3 months of treatment. Conclusion. Inclusion of α-lipoic acid product to complex treatment of patients with chronic generalized periodontitis combined with infiltrative pulmonary tuberculosis leads to faster clinical remission.


1950 ◽  
Vol 34 (5) ◽  
pp. 1363-1380
Author(s):  
Theodore L. Badger ◽  
William E. Patton

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