scholarly journals Sequencing and analysis of a South Asian-Indian personal genome

BMC Genomics ◽  
2012 ◽  
Vol 13 (1) ◽  
pp. 440 ◽  
Author(s):  
Ravi Gupta ◽  
Aakrosh Ratan ◽  
Changanamkandath Rajesh ◽  
Rong Chen ◽  
Hie Lim Kim ◽  
...  
2017 ◽  
Vol 49 (3) ◽  
pp. 294-302 ◽  
Author(s):  
Kavita Radhakrishnan ◽  
Shubhada Saxena ◽  
Regina Jillapalli ◽  
Yuri Jang ◽  
Miyong Kim

Author(s):  
Boria Majumdar

The first part of this chapter deals with the histories of South Asian/Indian cricket while the second part deals with Olympic sporting histories, a very recent addition to South Asian/Indian sports scholarship. It aims to reiterate that the story of Indian cricket cannot pass as the story of Indian sport. Cricket in contemporary South Asia and more so in India is imbued with a frenzied sense of hyper-nationalistic jingoism and is certainly one of the strongest of contemporary Indian allegiances. If only India or for that matter Pakistan, Sri Lanka, or Nepal had done well in Olympic sports, the popularity and commercial currency of international cricket would surely be under threat. Yet stories of failure on the Olympic stage, often for reasons unconnected to sport, help us understand postcolonial South Asia and more specifically India better.


2011 ◽  
Vol 1 (Suppl_1) ◽  
pp. A24-A25
Author(s):  
N. Dharni ◽  
N. Hanif ◽  
C. Bradley ◽  
G. Velikova ◽  
D. Stark ◽  
...  

2007 ◽  
Vol 24 (6) ◽  
pp. 585-593 ◽  
Author(s):  
A. Doshani ◽  
E. Pitchforth ◽  
C. J Mayne ◽  
D. G Tincello

Angiology ◽  
2020 ◽  
Vol 71 (6) ◽  
pp. 520-535 ◽  
Author(s):  
Anudeep Puvvula ◽  
Ankush D. Jamthikar ◽  
Deep Gupta ◽  
Narendra N. Khanna ◽  
Michele Porcu ◽  
...  

We evaluated the association between automatically measured carotid total plaque area (TPA) and the estimated glomerular filtration rate (eGFR), a biomarker of chronic kidney disease (CKD). Automated average carotid intima–media thickness (cIMTave) and TPA measurements in carotid ultrasound (CUS) were performed using AtheroEdge (AtheroPoint). Pearson correlation coefficient (CC) was then computed between the TPA and eGFR for (1) males versus females, (2) diabetic versus nondiabetic patients, and (3) between the left and right carotid artery. Overall, 339 South Asian Indian patients with either type 2 diabetes mellitus (T2DM) or CKD, or hypertension (stage 1 or stage 2) were retrospectively analyzed by acquiring cIMTave and TPA measurements of their left and right common carotid arteries (CCA; total CUS: 678, mean age: 54.2 ± 9.8 years; 75.2% males; 93.5% with T2DM). The CC between TPA and eGFR for different scenarios were (1) for males and females −0.25 ( P < .001) and −0.35 ( P < .001), respectively; (2) for T2DM and non-T2DM −0.26 ( P < .001) and −0.49 ( P = .02), respectively, and (3) for left and right CCA −0.25 ( P < .001) and −0.23 ( P < .001), respectively. Automated TPA is an equally reliable biomarker compared with cIMTave for patients with CKD (with or without T2DM) with subclinical atherosclerosis.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Rohit Ramadoss ◽  
Asma Altasan ◽  
May Cheung ◽  
Rosemary DeLuccia ◽  
Deeptha Sukumar ◽  
...  

Abstract Objectives The incidence rate of metabolic syndrome is higher in South Asian Indians (SAI) and is generally accompanied by changes in calcitropic hormones. Typically, these findings are reported in middle age or older adults and data in a younger population is scarce. The purpose of the study was to analyze the differences in calcitropic hormones and metabolic markers in younger South Asian Indian and Caucasian men Methods Caucasian or South Asian Indian men between 21–41 years of age were recruited for this study. Anthropometric measurements such as weight (kg), height (cm) and waist circumference (cm) were obtained. An 8-hour fasting blood sample was collected for analysis of serum concentrations of 25 hydroxyvitamin D (25OHD), parathyroid hormone (PTH), C-reactive protein (CRP), osteocalcin (OC), high molecular weight (HMW) adiponectin, glycemic indices, and lipid profile. Independent sample t-tests were used to report the mean differences between groups. The significance level was set for P < 0.05. Results A total of 26 men (13 SAIs and 13 Caucasians) completed the study. The mean age for SAI men was 27.82 ± 5.64 y and 27.39 ± 5.29 y for Caucasian men. Body mass index (BMI) averaged at 25.93 ± 3.97 kg/m2 for SAIs and 26.44 ± 2.49 kg/m2 for Caucasians. Serum 25(OH)D concentrations were lower in the SAI men (21.58 ± 8.11 ng/mL) compared to Caucasian men (29.14 ± 7.17 ng/mL) (P = 0.019). Serum concentrations of PTH were higher (P = 0.007) in the SAI men (72.39 ± 24.32 pg/mL) compared to Caucasian Men (45.30 ± 21.95 pg/mL). Furthermore, HMW adiponectin was significantly lower (P = 0.008) in SAIs (2.00 ±1.29 mg/L) compared to Caucasians (3.95 ± 2.01 mg/L). Glycemic indices, inflammatory markers, serum osteocalcin, and lipid profiles were not different between groups. Conclusions These results show that differences in calcitropic hormones are observed in young South Asian Indian men compared to Caucasians although differences in metabolic parameters do not exist at this point. Changes in calcitropic hormones may provide early insight into the development of metabolic syndrome in this population. Intervention studies should address whether correction of vitamin D status will delay the development of metabolic syndrome in this population. Funding Sources CNHP Seed Funding.


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