scholarly journals The "lipid accumulation product" performs better than the body mass index for recognizing cardiovascular risk: a population-based comparison

2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Henry S Kahn
2017 ◽  
Vol 4 (3) ◽  
pp. 728 ◽  
Author(s):  
Yashavanth H. S. ◽  
Bharath M. S.

Background: Metabolic syndrome (MS) is defined to be cluster of metabolic interrelated risk factors of such as obesity, elevated blood pressures, glucose metabolism disturbances and dyslipidemia. "Lipid accumulation product" (LAP) – is a simple and novel index based on a combination of an anthropometric dimension and a metabolic dimension.Methods: One hundred patients with metabolic syndrome were included in study. Data was collected through a prepared proforma which included various parameters related to history, thorough clinical examination, and laboratory parameters. Further the patients were assessed for the body mass index (BMI) and lipid accumulation product (LAP). BMI and LAP then correlated with metabolic syndrome.Results: Our present study is conducted among the population meeting the IDF criteria of MS, with a mean age of 54.52±12.65years and female predominance (54%). 72% and 62% of the study group had Diabetes Mellitus and Hypertension respectively. The mean BMI in our study is 29.04±5.11 kg/m2 with 25% of the population are non-obese. The average LAP value in our present study is 111.51±59.71 cm mmol/l and shown increasing trend with increasing age. LAP had a mean value of 85.19 cm mmol/l, 118.52 cm mmol/l and 122.37 cm mmol/l in the study population satisfying 3/5, 4/5 and 5/5 criteria of Metabolic Syndrome respectively. This shows LAP (P<0.001) has better correlation with MS when compared to BMI (P<0.001) in ANOVA test. In our present study, the presence of diabetes mellitus resulted in significant elevated LAP values i.e. 85.10±31.40 cm mmol/l among non-diabetics to 121.78±64.92 cm mmol/l among diabetics, which is of statistical significance (p value 0.005).Conclusions: LAP showed strong positive correlation with metabolic syndrome and it also positively correlated with increasing number of components of metabolic syndrome. LAP found to be better predictor of MS than BMI.


PLoS ONE ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. e29580 ◽  
Author(s):  
Julie A. Pasco ◽  
Geoffrey C. Nicholson ◽  
Sharon L. Brennan ◽  
Mark A. Kotowicz

2013 ◽  
Vol 28 (suppl 4) ◽  
pp. iv130-iv135 ◽  
Author(s):  
E. Cohen ◽  
A. Fraser ◽  
E. Goldberg ◽  
G. Milo ◽  
M. Garty ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Bâ Hamidou Oumar ◽  
Sangaré Ibrahima ◽  
Camara Youssouf ◽  
Sidibé Noumou ◽  
Coulibaly Souleymane ◽  
...  

Objective. This study aimed to compare 2 laborless tools, namely, the body mass index-based Framingham (bmi-Frm) and low-information WHO- (li-WHO-) based risk scores, and assess their agreement in outpatients in a cardiology department. Methodology. Data stem from a cross-sectional previous study performed from May to September 2016 in the Cardiology Department of University Hospital Gabriel Touré (UH-GT) in Bamako. All patients aged 40 and more were included in the study allowing the assessment of bmi-Frm and li-WHO prediction charts. The cardiovascular risk (CVR) was evaluated using a calculator prepared by D‘Agostino et al. for the bmi-Frm and the li-WHO chart for the Afro-D region of the WHO. The risk score for both ranged from <10 to ≥40. The data were entered in an ACCESS 2010 database, then processed by MS Excel 2010, and finally analysed using IBM SPSS Statistics 20. Continuous variables were presented as means and standard deviations, and categorical variables were presented as frequencies with percentages. P < 0.05 was considered the statistical significance level. After sample description, the risk score was assessed using bmi-Frm and li-WHO prediction tools. Finally, a kappa test was performed to check for the interreliability of both methods. For weighted kappa, coefficients were given all five classes of risk groups in 0, 25 steps from 1 for total concordance to 0 for total discordance. Results. This study involved 793 outpatients, 63.7% being female, 35.1% of them younger than 50 years, 57.9% with no formal education, and 67.7% with no medical insurance. Means for age, body mass index (BMI), and systolic blood pressure (SBP) were, respectively, 53.81 ± 16.729 years, 25.29 ± 06.151 kg/m2, and 139.49 ± 27.110 mm Hg. Using the li-WHO prediction chart gives a much higher proportion of low-risk patients compared to bmi-Frm (83.6 vs. 37.7). Sociodemographic characteristics such as education or income level were not different in risk score neither for the bmi-Frm nor for the li-WHO risk score. The percentage of agreement between both tools was 40.4%, and agreement (kappa of 0.1 and weighted kappa of 0.2) was found to be slight. Conclusion. Using the bmi-Frm and li-WHO tool gives a similar risk estimation in younger female patients. Older patients must be evaluated using high-information tools with cholesterol, e.g., versions of the Framingham risk equation or WHO using cholesterol. These must be confirmed in further studies and compared to data from prospective studies


2018 ◽  
Vol 10 (2) ◽  
pp. 79-87 ◽  
Author(s):  
Sarah J Holdsworth-Carson ◽  
Uri P Dior ◽  
Eliza M Colgrave ◽  
Martin Healey ◽  
Grant W Montgomery ◽  
...  

Introduction: There is a well-established inverse relationship between body mass index and frequency of endometriosis. However, these population-based studies have relied mostly on self-reported cases of endometriosis, rather than surgically confirmed endometriosis where disease severity has been objectively assessed. The aim of the current retrospective study was to establish whether the established relationship between endometriosis and low body mass index was independent of disease severity. Methods: Women with menstrual and/or pelvic pain undergoing laparoscopy for suspected endometriosis were recruited for this retrospective study (n = 509). Women were grouped by body mass index (kg/m2) according to World Health Organization criteria: underweight (<18.5), normal (18.5–24.99), pre-obese (25–29.99) or obese (≥30). Endometriosis was scored according to the revised American Fertility Society system. Data were analysed based on body mass index and endometriosis status to identify any relationship between body mass index and disease. Results: The average body mass index of women with endometriosis was 25.0 kg/m2. The body mass index distribution of women with endometriosis differed relative to women in the general population. As expected, fewer obese women had endometriosis than in the lower body mass index categories. However, the obese women who did have endometriosis had significantly higher revised American Fertility Society scores compared to women with normal and pre-obese body mass indices. Discussion: Our results are consistent with the established finding of an inverse relationship between body mass index and endometriosis. The novel finding from this study is that obesity is associated with increased disease severity and reduced frequency of stage I endometriosis. It remains unclear what role body mass index has in the cause or effect of endometriosis; we speculate that body mass index may be useful for sub-classifying the disease.


2017 ◽  
Vol 49 (5S) ◽  
pp. 111
Author(s):  
Philippe Gendron ◽  
François Trudeau ◽  
Claude Lajoie ◽  
Louis Laurencelle

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