scholarly journals Population-based study of ovarian cancer in Côte d'Or: prognostic factors and trends in relative survival rates over the last 20 years

BMC Cancer ◽  
2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Zeinab Hamidou ◽  
Sylvain Causeret ◽  
Tienhan S Dabakuyo ◽  
Julie Gentil ◽  
Laurent Arnould ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Prognostic Factors ◽  
Survival Rates ◽  
Relative Survival ◽  
Population Based ◽  
Population Based Study

The Availability of Histologic Grading among 5,923 Italian Cancer Patients and Its Relationship with Survival: A Population-Based Study

2000 ◽  
Vol 86 (2) ◽  
pp. 130-133 ◽  
Author(s):  
Emanuele Crocetti ◽  
Alessandro Barchielli ◽  
Andrea Amorosi ◽  
Francesco Bartoloni Saint Omer ◽  
Massimo Biancalani ◽  
...  
Keyword(s):  
Central Italy ◽  
Survival Rates ◽  
Relative Survival ◽  
Population Based ◽  
Italian Population ◽  
Population Based Study ◽  
Histologic Grading ◽  
Corpus Uteri ◽  
Disease Extension ◽  
Well Differentiated

Aim The specific goal of the study was to evaluate the availability of the histologic grading of cancer and its effect on survival in an Italian population-based cancer series. Methods Data were drawn from the Tuscany Cancer Registry, active in central Italy since 1985. Among the cases incident during the period 1985 to 1989, bladder, prostate, colon, corpus uteri, rectum and stomach cancers, for which the proportion of graded cases exceeded 50%, were analyzed. Overall, 5,923 cancer cases were included. Ten-year relative survival rates by grade were computed. Results Overall, data on histologic grading was available only for 38% of cases. The sites most frequently graded were urinary bladder (80%), prostate (73%), colon (71%), corpus uteri (69%), rectum (65%) and stomach (56%). For all the cancer sites analyzed, the 10-year relative survival rates increased as the histologic grading improved. The grade distribution resulted related also to the disease extension, more limited the extension higher the proportion of well differentiated cases. Conclusions Due to the evidenced importance of histologic grading as a valuable prognostic factor, it should be requested by clinicians and reported by pathologists more frequently than has been done in the area.

Analyzing Survival Trends in Multiple Myeloma Patients in Pre and Post-Bortezomib Era Using the SEER Database

Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 2639-2639
Author(s):  
Jayadev Manikkam Umakanthan ◽  
Dipesh Uprety ◽  
Vineela Kasireddy
Keyword(s):  
Multiple Myeloma ◽  
Survival Rate ◽  
Survival Rates ◽  
Relative Survival ◽  
Population Based ◽  
P Value ◽  
Relative Standard Error ◽  
Population Based Study ◽  
Male And Female ◽  
Relative Standard

Abstract Background: Bortezomib is an antineoplastic agent that acts through protease inhibition. Since, its approval in 2003 by U.S. Food and Drug administration, it has been used religiously for multiple myeloma. There is no current population based study that assesses the survival benefit in multiple myeloma from bortezomib. We conducted a population based study to evaluate the relative survival rates in multiple myeloma patients in pre and post-Bortezomib era in the United States. Methods: We analyzed the Surveillance, Epidemiology, and End Results (SEER) 18 registry database to compare five-year relative survival rates (RS) among multiple myeloma patients. The study arms were categorized by gender (male and female), race (Caucasians and African-Americans) and age (20-59, ≥60 years). The RS were compared between pre-bortezomib era (1991-2002) and post-bortezomib era (2004-2011). The survival rate accompanied standard errors and the statistical significance was defined as p value <0.05. Results: The database comprised of 57,328 patients. The RS have improved significantly during post-bortezomib era in all cohorts under consideration. There was no significant difference in survival rate between male and female and between the African American and Caucasian. However, the relative survival was much better with the young adult (20-59 years) as compared to adult ≥60 years. The table detailing the relative survival is given below. Conclusion: The Primary treatment protocols for Multiple Myeloma have changed dramatically since the approval of Bortezomib in 2003. Other novel agents introduced in the last decade include thalidomide, Lenalidomide and liposomal doxorubicin that are used in conjunction with Bortezomib. Survival trends continue to improve and we believe this modest improvement in survival rate is mainly due to the introduction of Bortezomib and other novel agents. The next challenge is to find new drugs which would prevent relapses and further prolong survival. Abstract 2639. Table.Study armSubclass of cohortsPre-bortezomib era (1991-2002)Post- bortezomib era (2004-2011)Z scoreP ValueNRS (%)Relative Standard Error (SE) (%)NRS (%)Relative Standard Error (SE) (%) GenderMale13,06634.60.517,76546.10.615.904<0.0001Female11,58032.10.514,91743.70.614.765<0.0001 RaceCaucasian18,83632.90.423,98145.00.519.259<0.0001African American4,27434.70.86,39145.10.98.488<0.0001 Age group20-596,35848.10.69,43960.20.712.920<0.0001>=6018,28827.80.423,24338.40.516.606<0.0001 Total: male and female: 1991-2002; 24,646, RS 33.4%; SE 0.3%; 2004-2011; 32,682, RS 45.0%, SE 0.4%; Z score 21.766, P value <0.0001. Disclosures No relevant conflicts of interest to declare.

scholarly journals Oropharyngeal Cancer Survival: A Population-Based Study of Patients Diagnosed between 1978 and 2002

ISRN Oncology ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Dyego Leandro Bezerra de Souza ◽  
María Milagros Bernal ◽  
Javier Jerez Roig ◽  
Maria Paula Curado
Keyword(s):  
Oropharyngeal Cancer ◽  
Cancer Survival ◽  
Survival Rates ◽  
Age Groups ◽  
Relative Survival ◽  
Population Based ◽  
First Year ◽  
Population Based Study ◽  
Kaplan Meier ◽  
One Year

Objective. This paper aims at studying oropharyngeal cancer survival from the Population-Based Cancer Registry of Zaragoza, Spain, for the 1978–2002 period. Methods. The survival rates were calculated by the Kaplan-Meier method, and the automated calculation method of the Catalan Institute of Oncology was utilized to obtain the relative survival. Results. The oropharyngeal cancer survival rate was 61.3% in the first year and 33.9% in the fifth year. One-year relative survival was 62.2% (CI 95%: 57.4–67.4), and five-year relative survival was 36.6% (CI 95%: 31.8–42.1). Comparison of survival rates by sex revealed statistically significant differences (P value = 0.017) with better survival in women. There were no differences when comparing the three age groups and the three studied time periods 1978–1986, 1987–1994, and 1995–2002. Conclusions. The data suggests that there were no significant changes in oropharyngeal cancer survival in the province of Zaragoza throughout the years.

scholarly journals Racial disparities in incidence and outcome in multiple myeloma: a population-based study

Blood ◽  
2010 ◽  
Vol 116 (25) ◽  
pp. 5501-5506 ◽  
Author(s):  
Adam J. Waxman ◽  
Pamela J. Mink ◽  
Susan S. Devesa ◽  
William F. Anderson ◽  
Brendan M. Weiss ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Large Scale ◽  
Age Of Onset ◽  
Hematologic Malignancy ◽  
Survival Rates ◽  
Relative Survival ◽  
Population Based ◽  
Population Based Study ◽  
Entire Study ◽  
Disease Specific

Abstract Multiple myeloma (MM) is the most common hematologic malignancy in blacks. Some prior studies suggest inferior survival in blacks; others suggest similar survival. Using the original 9 Surveillance, Epidemiology, and End Results registries, we conducted a large-scale population-based study including 5798 black and 28 939 white MM patients diagnosed 1973-2005, followed through 2006. Age-adjusted incidence rates, disease-specific survival, and relative survival rates were calculated by race, age, and time period of diagnosis. Mean age at diagnosis was 65.8 and 69.8 years for blacks and whites, respectively (P < .001). Incidence among blacks was m twice that among whites; this disparity was greater among patients < 50 years (P = .002). Over the entire study period, disease-specific and relative survival rates were higher in blacks than whites (P < .001). For whites, 5-year relative survival rates increased significantly 1973-1993 to 1994-1998 (26.3% to 30.8%; P < .001) and 1994-1998 to 1999-2005 (30.8% to 35.0%; P = .004). Survival improvements among blacks were smaller and nonsignificant (1973-1993 to 1999-2005: 31.0% to 34.1%; P = .07). We found (1) a younger age of onset among blacks; (2) better survival in blacks 1973-2005; and (3) significant survival improvement among whites over time, with smaller, nonsignificant change seen among blacks, possibly due to unequal access to and/or disparate responsiveness to novel therapies.

scholarly journals Population-based study of breast cancer survival in Cote d’Or (France): prognostic factors and relative survival

2008 ◽  
Vol 19 (2) ◽  
pp. 276-283 ◽  
Author(s):  
T.S. Dabakuyo ◽  
F. Bonnetain ◽  
P. Roignot ◽  
M.-L. Poillot ◽  
G. Chaplain ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Cancer Survival ◽  
Relative Survival ◽  
Population Based ◽  
Breast Cancer Survival ◽  
Population Based Study

scholarly journals Population-based study of breast cancer in older women: prognostic factors of relative survival and predictors of treatment

BMC Cancer ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Pegdwende Olivia Dialla ◽  
Tienhan Sandrine Dabakuyo ◽  
Sophie Marilier ◽  
Julie Gentil ◽  
Patrick Roignot ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Older Women ◽  
Relative Survival ◽  
Population Based ◽  
Population Based Study

scholarly journals Period Analysis of Intraracial Differences in Incidence and Survival Rates in Epithelial Ovarian Cancer

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Lili Han ◽  
Sulaiya Husaiyin ◽  
Jing Liu ◽  
Miherinisha Maimaiti ◽  
Mayinuer Niyazi ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Survival Rate ◽  
Epithelial Ovarian Cancer ◽  
Median Survival ◽  
Survival Rates ◽  
Relative Survival ◽  
Population Based ◽  
Relative Survival Rate ◽  
Kaplan Meier ◽  
The Difference

Background. To explain the difference in the incidence and relative survival in a population-based cohort of women with epithelial ovarian cancer (EOC) postdiagnosis in the last forty years. EOC is the most common type of all ovarian cancers, but there is inadequate information about the variations related to long-term EOC survival. Methods. We acquired the incidence and relative survival rate data from the Surveillance, Epidemiology, and End Results (SEER) registries to analyze the epidemiological variations from 1974 to 2013 in EOC-affected individuals. The survival disparities in EOC-specific individuals due to age, race, and socioeconomic status (SES) were performed by Kaplan-Meier analysis. The Results. The overall incidence of EOC progressively declined to 9.0 per 100,000 from 11.4 in the last forty years. The median survival rate improved to 48 months in the first decade from a previous of 27 months in the fourth decade. The 5-year relative survival rate (RSR) increased to 44.3% that was previously 32.3% at the same time. However, between whites and blacks, an increase from 11 to 18 months was observed in the median survival differences. Between the low and high poverty groups, it was increased from 7 months to 12 months, respectively. Conclusions. The incidence rate of RSR and EOC-specific individuals in the last forty years was improved. However, the survival rates among different races and SES differed over time.

scholarly journals Incidence, Mortality, Survival, and Prognostic Analysis of Epithelial Ovarian Cancer Patients in Brunei Darussalam: A Population-Based Study

2021 ◽  
Author(s):  
Elvynna Leong ◽  
Sok King Ong ◽  
Fadzilah Jali ◽  
Lin Naing
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Cancer Patients ◽  
Survival Rates ◽  
Mortality Rates ◽  
Population Based ◽  
Age At Diagnosis ◽  
Population Based Study ◽  
Brunei Darussalam ◽  
Incidence And Mortality

Abstract Background Ovarian cancer is the fifth most common cancer among females in Brunei Darussalam in 2017. This study aims to provide nationwide cancer statistics including cancer incidence, mortality, survival rates for women diagnosed with epithelial ovarian cancer, and evaluate the prognostic factors of epithelial ovarian cancer patients survival in Brunei Darussalam. Methods This is a retrospective population-based study of patients diagnosed with epithelial ovarian cancer between 1st January 2007 and 31st December 2017 in Brunei Darussalam. Crude, age-specific, age-standardized incidence and mortality rates per 100,000 women were calculated. Kaplan-Meier survival analysis method was used to determine the overall 5-years survival rate of epithelial ovarian cancer patients. Log-rank test was used to examine the differences in survival between groups. The Multivariable Cox Proportional Hazard (PH) regression models were used to estimate the hazard ratio (HRs) for overall survival and to identify the prognostic factor of epithelial ovarian cancer patients. PH assumption over time for these models were evaluated. Results A total of 207 patients were included in the study. The crude incidence and mortality rates were 9.7 and 3.6 per 100,000 respectively while the age-standardized incidence and mortality rates were 11.3 (95% CI: 9.7, 12.9) and 4.5 (95% CI: 3.4, 5.6) per 100,000 respectively in the period 2007-2017. The overall mean age at diagnosis was 48.4 (standard deviation=15.3) years. The overall survival rates at 1, 3, and 5 years for epithelial ovarian cancer patients were 79.7%, 69.7%, and 61.4% respectively. Age at diagnosis, district, cancer stage, and histology were the significant prognostic factors for epithelial ovarian cancer patients’ survival. Older age at diagnosis (\(\ge\)70 years vs <40 years), regional or advanced stage (vs localized stage) and having undifferentiated or other epithelial ovarian (vs serous carcinoma) were associated with having higher hazard of death while patients residing in Belait district (vs Brunei Muara) was associated with having lower hazard. Conclusion More efforts and research should be made to detect the disease at early stage through education and public awareness to ensure the availability of high-quality care for all women with ovarian cancer and to improve the survival rates of patients with ovarian cancer.

Sign in / Sign up

Export Citation Format

Share Document