scholarly journals P323: Epidemiological study of drug administration routes (dar) in the department of pediatrics, Gabriel Touré hospital. Mali

2013 ◽  
Vol 2 (Suppl 1) ◽  
pp. P323
Author(s):  
M Daouda ◽  
AS Kaya ◽  
B Traoré ◽  
L Bengaly ◽  
M Sacko ◽  
...  
Keyword(s):  
Epidemiological Study ◽  
Drug Administration ◽  
Drug Administration Routes ◽  
Administration Routes

Drug Delivery, Monitoring, and Interactions

2018 ◽  
Author(s):  
Eelco F. M. Wijdicks ◽  
Sarah L. Clark
Keyword(s):  
Drug Delivery ◽  
Drug Interactions ◽  
Drug Administration ◽  
Clinical Relevance ◽  
Pharmacokinetic Parameters ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Drug Administration Routes ◽  
Administration Routes ◽  
Main Components ◽  
Drug Errors

This chapter outlines the typical pathway of an administered drug and the factors that affect it. The main components that determine a drug’s pharmacokinetics and pharmacodynamics are discussed. Issues important for the physician such as Pharmacokinetic parameters, drug administration routes, and principles of drug interactions are highlighted. Problems with inadvertently holding home or maintenance medications and other drug errors are outlined. Pharmacogenomics and its emerging clinical relevance is introduced.

scholarly journals Nursing knowledge and practices regarding subcutaneous fluid administration

2017 ◽  
Vol 70 (5) ◽  
pp. 1096-1105 ◽  
Author(s):  
Nathália Silva Gomes ◽  
Andrea Mara Bernardes da Silva ◽  
Luana Barbosa Zago ◽  
Érica Carneiro de Lima e Silva ◽  
Elizabeth Barichello
Keyword(s):  
Experimental Studies ◽  
Subcutaneous Administration ◽  
Adult Health ◽  
Drug Administration Routes ◽  
Cross Sectional ◽  
Nursing Knowledge ◽  
Administration Routes ◽  
Quantitative Studies ◽  
Literature Reviews ◽  
Proven Efficacy

ABSTRACT Objective: To describe the evidence in the literature regarding the knowledge and practices of the nursing team about subcutaneous administration of drugs and fluids in adults. Method: Integrative review of the literature using the descriptors “nursing”, “hypodermoclysis”, “drug administration routes”, “adult health,” and “knowledge,” in English, Spanish, and Portuguese, with no publication deadline. Of the 569 articles found, eight made up the sample. Results: A predominance of international journals (75%) with more than five years of publication (62.5%). The analysis of the methodological characteristics showed a predominance of literature reviews (25%), quantitative studies (62.5%), cross-sectional studies (50%), and non-experimental studies (50%). Conclusion: Although it is an old technique with proven efficacy, hypodermoclysis is still little used, a puzzling fact due to its advantages and indications for any age.

scholarly journals The Investigation of Knowledge and Behavior of Nursing and Midwives on Rational Drug Usage

2020 ◽  
Author(s):  
Asuman Çobanoğlu ◽  
Belkız Kızıltan
Keyword(s):  
Side Effects ◽  
Drug Utilization ◽  
Drug Administration ◽  
Cross Sectional Study ◽  
Food Allergies ◽  
Cross Sectional ◽  
Administration Routes ◽  
Rational Drug ◽  
Administration Error ◽  
And Behaviors

OBJECTIVE: This study was conducted to examine the knowledge and behaviors of midwives and nurses in regards to rational drug utilization. METHOD: The descriptive and cross-sectional study was conducted in a training and research hospital of obstetrics and pediatrics, which accommodates 86 midwives and 49 nurses, from September 1 through October 1, 2017, with the participation of 27 midwives and 25 nurses (38.5%) totaling to 52 people. Granted the necessary permissions, data were collected by “Nurse / Midwife Self-Descriptive Form” and through face-to-face interviews, and were evaluated using descriptive statistical methods. FINDINGS: Of the participants of the research, 50.9% were midwives and 47.2% were nurses. The most frequent drug administration error encountered by 48% of the midwives and 32% of the nurses was found to be untimely administration of medication. It was determined that 81.5% of the midwives and 80% of the nurses know how to report side effects and that 77.8% of the midwives and 96% of the nurses have never reported any side effects. 81.5% and 80% of the midwives and the nurses, respectively, stated that prior to administering medication, they inquire whether patients have drug or food allergies; 34.6% of the midwives and 30.8% of the nurses stated that unused drugs were delivered back to the pharmacy; and all participants confirmed checking the expiration dates of drugs used in the medical service. Midwives and nurses were seen to consider good their level of knowledge in intended utilization of drugs, administration routes, and duration of the effects. CONCLUSION: It has been concluded that the knowledge and behaviors of midwives and nurses in regards to rational drug utilization are satisfactory but that there is a general need for training about rational drug utilization, especially drug administration and side effect notification.

scholarly journals First-line management of canine status epilepticus at home and in hospital-opportunities and limitations of the various administration routes of benzodiazepines

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Marios Charalambous ◽  
Holger A. Volk ◽  
Luc Van Ham ◽  
Sofie F. M. Bhatti
Keyword(s):  
Status Epilepticus ◽  
Drug Administration ◽  
Hospital Setting ◽  
First Line ◽  
Onset Of Action ◽  
Systemic Complications ◽  
Administration Routes ◽  
The Impact ◽  
Line Management ◽  
At Home

AbstractStatus epilepticus (SE) or prolonged epileptic seizure activity is a common neurological emergency with a high mortality rate and, if left untreated, can lead to irreversible cerebral damage and systemic complications. Fast and effective first-line management is of paramount importance, particularly in the at-home management of seizures where drug administration routes are limited. Benzodiazepines (BZDs) have been exclusively used in veterinary medicine for decades as first-line drugs based on their high potency and rapid onset of action. Various administration routes exist in dogs, such as oral, intravenous, intramuscular, rectal, and intranasal, all with different advantages and limitations. Recently, intranasal drug delivery has become more popular due to its unique and favourable characteristics, providing potential advantages over other routes of drug administration in the management of canine SE. This narrative review provides an outline of the management of SE at home and in a hospital setting, discusses considerations and challenges of the various routes of BZD administration, and evaluates the impact of intranasal drug administration (nose-brain pathway) for controlling canine SE at home and within hospital settings.

Nanotechnology-based drug delivery systems as potential for skin application: a review

2020 ◽  
Vol 27 ◽  
Author(s):  
Franciele Garcia Baveloni ◽  
Bruno Vincenzo Fiod Riccio ◽  
Leonardo Delello Di Filippo ◽  
Mariza Aires Fernandes ◽  
Andréia Bagliotti Meneguin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Administration ◽  
Drug Delivery Systems ◽  
Polymeric Nanoparticles ◽  
Large Body ◽  
Delivery Systems ◽  
Multiple Drug ◽  
Promising Alternative ◽  
Administration Routes ◽  
Main Barrier

: Administration of substances through the skin represents a promising alternative, in relation to others drug administration routes, due to its large body surface area, in order to offer ideal and multiple sites for drug administration. In addition, the administration of drugs through the skin avoids first-pass metabolism, allowing an increase in the bioavailability of drugs, as well as reducing their side effects. However, the stratum corneum (SC) comprises the main barrier of protection against external agents, mainly due to its structure, composition and physicochemical properties, becoming the main limitation for the administration of substances through the skin. In view of the above, pharmaceutical technology has allowed the development of multiple drug delivery systems (DDS), which include liquid crystals (LC), cubosomes, liposomes, polymeric nanoparticles (PNP), nanoemulsions (NE), as well as cyclodextrins (CD) and dendrimers (DND). It appears that the DDS circumvents the problems of drug absorption through the SC layer of the skin, ensuring the release of the drug, as well as optimizing the therapeutic effect local. This review aims to highlight the DDS that include LC, cubosomes, lipid systems, PNP, as well as CD and DND, to optimize topical skin therapies.

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