scholarly journals Burden for the infection control programme of a European hospital of getting prepared and treat a patient (PT) with Ebola virus disease (EVD)

Author(s):  
A Iten ◽  
MN Charaïti ◽  
C Ginet ◽  
P Brennenstuhl ◽  
D Pittet
2020 ◽  
Vol 41 (4) ◽  
pp. 385-390
Author(s):  
Colleen S. Kraft ◽  
Aneesh K. Mehta ◽  
Jay B. Varkey ◽  
G. Marshall Lyon ◽  
Sharon Vanairsdale ◽  
...  

AbstractObjective:Healthcare personnel (HCP) were recruited to provide serum samples, which were tested for antibodies against Ebola or Lassa virus to evaluate for asymptomatic seroconversion.Setting:From 2014 to 2016, 4 patients with Ebola virus disease (EVD) and 1 patient with Lassa fever (LF) were treated in the Serious Communicable Diseases Unit (SCDU) at Emory University Hospital. Strict infection control and clinical biosafety practices were implemented to prevent nosocomial transmission of EVD or LF to HCP.Participants:All personnel who entered the SCDU who were required to measure their temperatures and complete a symptom questionnaire twice daily were eligible.Results:No employee developed symptomatic EVD or LF. EVD and LF antibody studies were performed on sera samples from 42 HCP. The 6 participants who had received investigational vaccination with a chimpanzee adenovirus type 3 vectored Ebola glycoprotein vaccine had high antibody titers to Ebola glycoprotein, but none had a response to Ebola nucleoprotein or VP40, or a response to LF antigens.Conclusions:Patients infected with filoviruses and arenaviruses can be managed successfully without causing occupation-related symptomatic or asymptomatic infections. Meticulous attention to infection control and clinical biosafety practices by highly motivated, trained staff is critical to the safe care of patients with an infection from a special pathogen.


Author(s):  
Ermira Tartari ◽  
Benedetta Allegranzi ◽  
Brenda Ang ◽  
Neville Calleja ◽  
Peter Collignon ◽  
...  

2019 ◽  
Author(s):  
Guyguy Kabundi Tshima ◽  
Kaleb Tshimungu Kalala

AbstractHealth workers play an important role during epidemics, but there is limited research on hospital activities on infection control practices in the Democratic Republic of the Congo and how health workers can cope during a probable health epidemic in Kinshasa city. The determinants of the current Ebola Virus Disease in the geographical distribution remain poorly understood. The World Health Organization’s Health Regulation Committee decided on Wednesday July 17th, 2019 to declare the Ebola haemorrhagic fever epidemic in the provinces of North Kivu and Ituri as a health emergency of international concern. The country struggles to control it against a backdrop of a health system that is already overburdened. To test the influence of the challenges of a contamination in the context of an Ebola outbreak that may face health workers and their coping strategies in thirteen hospitals of reference in Kinshasa, we conducted a survey hoping to educate or remember good practices for health workers in Kinshasa that is also available for health workers in the East Area of the country in which the ongoing Ebola outbreak progress is spreading (North Kivu and Ituri). For the ongoing outbreak, we obtained data from the Ministère de la Santé Publique of the Democratic Republic of the Congo where cases are classified as suspected, probable, or confirmed using national case definitions. We found that the ongoing Ebola virus outbreak in the Democratic Republic of the Congo has similar epidemiological features to previous Ebola virus disease outbreak in Sierra Leone that was well described. For the qualitative study about the biosecurity in thirteen hospitals of reference in Kinshasa, we found that the Bondeko-Ngaliema Monkole group has occupied the first rank, while the group Kintambo-King Baudouin-Ndjili-Makala occupied the other end of the scale; the other health facilities occupied an intermediate position. Among the 7 hospitals which were placed at the top of this classification of biosecurity, 5 were massively subsidized by international NGO, which explains to a great extent their performances in one hand, another hand finding its explanation in the quality of their management. It is the case of Bondeko, Monkole, Kalembe-Lembe, St Joseph and Kingasani 2.Author summaryThe determinants of the transmission are poorly understood, but a growing body of evidence supports an important role of the lack of prevention in the dissemination of Ebola virus. The results of our study conducted in 13 hospitals of reference in Kinshasa suggest that the biosecurity measures—which were introduced in Kinshasa hospitals policies through prevention since Ebola outbreaks—have been respected by 75% and had 25% of parameters to be improved. Biosecurity is an important concept; it seems to be a vector for the prevention of Ebola Virus Disease. In addition, the lack of biosecurity observation may have a role in the contamination of Ebola Virus Disease in local populations found in invaded areas. This study provides knowledge into the preventive measures influencing Ebola Virus Disease populations, thereby determining in perspective a study on meat consumption of animals found dead in forests that will be a risk for human infection as the Democratic Republic of the Congo has many forests.


2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Aisha Abubakar ◽  
Kabir Sabitu ◽  
Mohammed Nasir Sambo ◽  
Abdulrazaq Gobir ◽  
Sani Abrahim ◽  
...  

ObjectiveTo assess the formation and function of a joint committee of the Ahmadu Bello University (ABU) and the Ahmadu Bello University Teaching Hospital (ABUTH) to prevent and control EVD in Zaria and the North West sub region of Nigeria.IntroductionThe Ebola Virus Disease (EVD) outbreak in West Africa was unprecedented in spread and its attendant response. There were over 15 000 confirmed cases and over 9 000 suspected cases. The response to the outbreak was massive within Africa and beyond. The outbreak in Nigeria affected 19 people and led to 7 deaths (CFR 37%).There were more than 891 contacts of these cases under surveillance as at 23rd September 2014. Nigeria was declared EVD free by the World Health Organization in October 2014.Nationwide there was targeted preparedness to prevent and control EVD. In Zaria, this led to the formation of a joint committee of the Ahmadu Bello University (ABU) and the Ahmadu Bello University Teaching Hospital (ABUTH) to prevent and control EVD in Zaria and the sub region as a whole.MethodsA joint multidisciplinary committee was formed by ABU and ABUTH with representatives from the Department of Community Medicine, Internal Medicine, Nursing sciences, Veterinary Public Health, Medical Microbiology, Mass Communication, Directorate of Public Affairs ABU Zaria, General Administration and Management services division ABUTH, the University Health Services and the Centre for Disease Risk Management under the Department of Geography. Four subcommittees were created steered by the main committee. The subcommittees were Surveillance; Case Management; Infection Control and Social and Mass mobilization subcommitteesResultsThe committee conducted seminars and trainings in case management, surveillance and infection control. Mass media campaigns included radio jingles production and airing as well as production of flyers and posters on EVD prevention and control. There was a phone in live radio programme. Screening exercise for raised temperature was conducted using laser thermometers at main entry points. A case of suspected EVD was managed who turned out to be a case of dengue haemorrhagic fever.ConclusionsThe committee was enriched by its multidisciplinary nature and a blueprint for the control and prevention of EVD was developed in line with national and global standards. The committee was hampered with lack of funds to implement fully the blueprint for the prevention and control of EVD in Zaria and its environs. The committee transformed into the ABU/ABUTH Epidemic Preparedness and Response Committee after the outbreak was over to address other emerging epidemics.ReferencesABU/ABUTH Joint Committee For The Prevention And Control Of Ebola Virus Disease (ABUPACE) Blueprint For Prevention And Control Of Ebola Virus Disease In ABU/ABUTH Zaria 2014. Pages 1-44World Health Organization. WHO declares end of Ebola outbreak in Nigeria www.who.int/mediacentre/news/statements/2014/nigeria-ends-ebola/en/ 


2014 ◽  
Vol 9 (1) ◽  
pp. 33-37 ◽  
Author(s):  
Eric Toner ◽  
Amesh Adalja ◽  
Thomas Inglesby

AbstractThe size of the world’s largest Ebola outbreak now ongoing in West Africa makes clear that further exportation of Ebola virus disease to other parts of the world will remain a real possibility for the indefinite future. Clinicians outside of West Africa, particularly those who work in emergency medicine, critical care, infectious diseases, and infection control, should be familiar with the fundamentals of Ebola virus disease, including its diagnosis, treatment, and control. In this article we provide basic information on the Ebola virus and its epidemiology and microbiology. We also describe previous outbreaks and draw comparisons to the current outbreak with a focus on the public health measures that have controlled past outbreaks. We review the pathophysiology and clinical features of the disease, highlighting diagnosis, treatment, and hospital infection control issues that are relevant to practicing clinicians. We reference official guidance and point out where important uncertainty or controversy exists. (Disaster Med Public Health Preparedness. 2014;0:1-5)


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