scholarly journals Triglycerides and blood pressure in relation to circulating CD34-positive cell levels among community-dwelling elderly Japanese men: a cross-sectional study

2017 ◽  
Vol 22 (1) ◽  
Author(s):  
Yuji Shimizu ◽  
Shimpei Sato ◽  
Yuko Noguchi ◽  
Jun Koyamatsu ◽  
Hirotomo Yamanashi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Sectional Study ◽  
Cross Sectional ◽  
Japanese Men ◽  
Elderly Japanese

scholarly journals Heart rate variability and blood pressure among Japanese men and women: a community-based cross-sectional study

2014 ◽  
Vol 37 (8) ◽  
pp. 779-784 ◽  
Author(s):  
Hiromi Mori ◽  
Isao Saito ◽  
Eri Eguchi ◽  
Koutatsu Maruyama ◽  
Tadahiro Kato ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Japanese Men ◽  
Men And Women

scholarly journals Physical performance in relation to preserved ratio impaired spirometry: a cross-sectional study of community-dwelling older Japanese adults

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kunihiko Anami ◽  
Shin Murata ◽  
Hideki Nakano ◽  
Koji Nonaka ◽  
Hiroaki Iwase ◽  
...  
Keyword(s):  
Older Adults ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Normal Lung ◽  
Sectional Study ◽  
Cross Sectional ◽  
Physical Functions ◽  
Elderly Japanese ◽  
Community Dwelling Older Adults

AbstractPreserved ratio impaired spirometry (PRISm) is associated with an increased mortality rate; however, its characteristics have not been clearly identified in Japan. This cross-sectional study of community-dwelling older adults compared physical function between people with PRISm and those with no respiratory issues, from 2014 to 2019. We collected demographic data through interviews and measured respiratory and physical functions. We included 668 older adults (male, 23.5%; mean age, 72.8 ± 5.6 years); the prevalence of PRISm was 12%, while the prevalence of obstruction was 6.9%. Propensity score matching was used to identify control subjects with normal spirometry (n = 80) while minimizing the effects of confounders during comparisons with the PRISm population (n = 80). Compared with community-dwelling older adults with normal lung capacity, older adults with PRISm had a lower forced vital capacity (%FVC; 68.7 ± 9.1% vs. 92.5 ± 12.7%, p < 0.001), lower core muscle endurance (sit-up test: 6.7 ± 5.8 vs. 8.7 ± 6.0, p = 0.032), and a longer one-leg stance duration (52.4 ± 41.1 s vs. 36.4 ± 34.1 s, p = 0.008). In multivariable logistic regression, %FVC and increased one-leg stance were independent predictors of PRISm status. The prevalence of PRISm among community-dwelling elderly Japanese exceeds that of obstructive lung disease and is associated with reduced %FVC and better performance on balance testing.

scholarly journals Contribution of VEGF polymorphism rs3025020 to short stature and hypertension in elderly Japanese individuals: a cross-sectional study

2021 ◽  
Vol 40 (1) ◽  
Author(s):  
Yuji Shimizu ◽  
Hirotomo Yamanashi ◽  
Shin-Ya Kawashiri ◽  
Kenichi Nobusue ◽  
Fumiaki Nonaka ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Short Stature ◽  
Reference Group ◽  
Cross Sectional Study ◽  
Inverse Association ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vegf Polymorphism ◽  
Elderly Japanese ◽  
Endothelial Growth Factor

Abstract Background Recently, short stature has been revealed to be positively associated with hypertension, possibly because this indicates lower activity of vascular maintenance, such as angiogenesis. Vascular endothelial growth factor (VEGF) polymorphism (rs3025020) plays an important role in the progression of angiogenesis and may be associated with both hypertension and hypertension-associated short stature. Methods A cross-sectional study of 1377 elderly Japanese individuals aged 60–89 years was conducted. Short stature was defined as the lowest tertile of height (< 160.8 cm for men and < 148.7 cm for women). Hypertension was defined as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg and/or antihypertensive medication use. Results Independent of known cardiovascular risk factors, short stature was found to be positively associated with hypertension; the fully adjusted odds ratio (OR) and 95% confidence interval (CI) for hypertension were 1.51 (1.17, 1.96). With the reference group of carriers of the major allele of rs3025020, TT-homozygotes showed significantly lower OR for hypertension and short stature; the fully adjusted ORs (and 95% CIs) were 0.60 (0.41, 0.90) for hypertension and 0.59 (0.38, 0.91) for short stature, respectively. Conclusions Angiogenesis-related genetic factor (rs3025020) is associated with hypertension and short stature, whereas short stature is positively associated with hypertension. Further investigation is necessary in this regard; the capacity for angiogenesis might partly explain the mechanism underlying the inverse association between height and hypertension.

scholarly journals Relationships between Physical Activity, Sleeping Time, and Psychological Distress in Community-Dwelling Elderly Japanese

Medicina ◽  
2019 ◽  
Vol 55 (7) ◽  
pp. 318 ◽  
Author(s):  
Yamamoto ◽  
Suzuki ◽  
Owari ◽  
Miyatake
Keyword(s):  
Physical Activity ◽  
Psychological Distress ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sleeping Time ◽  
Elderly Japanese ◽  
Walking Time ◽  
Japanese Subjects

Background and objectives: It is well-known that lifestyle is closely associated with psychological distress in many elderly subjects. However, the effect of intervention with physical activity and/or sleeping on psychological distress has not been fully discussed. The purpose of this cross-sectional study was to investigate the relationships between physical activity, sleeping time, and psychological distress in community-dwelling elderly Japanese subjects. Materials and Methods: A total of 108 elderly Japanese (31 men and 77 women) subjects were enrolled in this cross-sectional study. Psychological distress was evaluated using the K6 questionnaire. Physical activity, including sedentary behavior, was measured using a tri-accelerometer. Sleeping time was evaluated using a self-reported questionnaire. Results: The median of the K6 scores was 1.0 (0–18), and the sedentary behavior (%) and walking time (minutes/day) were 57.2 ± 10.7 and 80.7 (17.9–222.4), respectively. Sleeping time was negatively correlated with psychological distress. In addition, multiple linear regression showed that walking time and sleeping time were important factors for psychological distress, even after adjusting for confounding factors. Conclusions: These results suggest that increased walking time and sleeping time may be beneficial for reducing psychological distress in community-dwelling elderly Japanese subjects.

scholarly journals Gamma-glutamyl transpeptidase (γ-GTP) has an ambivalent association with hypertension and atherosclerosis among elderly Japanese men: a cross-sectional study

2019 ◽  
Vol 24 (1) ◽  
Author(s):  
Yuji Shimizu ◽  
Shin-Ya Kawashiri ◽  
Kairi Kiyoura ◽  
Kenichi Nobusue ◽  
Hirotomo Yamanashi ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Gamma Glutamyl Transpeptidase ◽  
Cross Sectional ◽  
Japanese Men ◽  
Gamma Glutamyl ◽  
Endothelial Repair ◽  
Bidirectional Association ◽  
Elderly Japanese ◽  
Glutamyl Transpeptidase

Abstract Background Even though there is bidirectional association between hypertension and atherosclerosis, atherosclerosis itself is involved in the process of endothelial repair. To clarify the association of endothelial repair with hypertension, a cross-sectional study was conducted. Methods We conducted a cross-sectional study of 562 elderly Japanese men aged 60–69. As gamma-glutamyl transpeptidase (γ-GTP) could act as a marker of oxidative stress that injures endothelial cell and higher levels of CD34-positive cell indicate a higher activity of endothelial repair, we therefore performed a CD34-positive level specific analysis of γ-GTP on atherosclerosis and hypertension. Results In the present study population, hypertension was independently and positively associated with atherosclerosis (multivariable odds ratio (OR) = 2.09 (1.30, 3.35)). Among participants with high CD34-positive cells, γ-GTP showed significant and positive association with atherosclerosis (OR of the log-transformed value of γ-GTP (OR) = 2.26 (1.32, 3.86)) but not with hypertension (OR = 0.77 (0.51, 1.17)). Among participants with low CD34-positive cells, even γ-GTP showed no significant association with atherosclerosis (OR = 0.92 (0.51, 1.68)), but was significantly and positively associated with hypertension (OR = 1.99 (1.27, 3.12)). Conclusions γ-GTP revealed to have ambivalent association with hypertension and atherosclerosis. Active endothelial repair that is associated with atherosclerosis might have beneficial association with hypertension.

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