scholarly journals Benchmarking machine learning models for late-onset alzheimer’s disease prediction from genomic data

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Javier De Velasco Oriol ◽  
Edgar E. Vallejo ◽  
Karol Estrada ◽  
José Gerardo Taméz Peña ◽  
The Alzheimer’s Disease Neuroimaging Initiative
Keyword(s):  
Machine Learning ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Late Onset ◽  
Classification Performance ◽  
Learning Models ◽  
Machine Learning Methods ◽  
Machine Learning Model ◽  
Cognitive Therapies ◽  
Machine Learning Models

Abstract Background Late-Onset Alzheimer’s Disease (LOAD) is a leading form of dementia. There is no effective cure for LOAD, leaving the treatment efforts to depend on preventive cognitive therapies, which stand to benefit from the timely estimation of the risk of developing the disease. Fortunately, a growing number of Machine Learning methods that are well positioned to address this challenge are becoming available. Results We conducted systematic comparisons of representative Machine Learning models for predicting LOAD from genetic variation data provided by the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. Our experimental results demonstrate that the classification performance of the best models tested yielded ∼72% of area under the ROC curve. Conclusions Machine learning models are promising alternatives for estimating the genetic risk of LOAD. Systematic machine learning model selection also provides the opportunity to identify new genetic markers potentially associated with the disease.

scholarly journals Automated Retraining of Machine Learning Models

2019 ◽  
Vol 8 (12) ◽  
pp. 445-452
Keyword(s):  
Machine Learning ◽  
Input Data ◽  
Research Work ◽  
Learning Models ◽  
Machine Learning Methods ◽  
Machine Learning Model ◽  
Crucial Component ◽  
Conventional Machine ◽  
Over Time ◽  
Machine Learning Models

Data is the most crucial component of a successful ML system. Once a machine learning model is developed, it gets obsolete over time due to presence of new input data being generated every second. In order to keep our predictions accurate we need to find a way to keep our models up to date. Our research work involves finding a mechanism which can retrain the model with new data automatically. This research also involves exploring the possibilities of automating machine learning processes. We started this project by training and testing our model using conventional machine learning methods. The outcome was then compared with the outcome of those experiments conducted using the AutoML methods like TPOT. This helped us in finding an efficient technique to retrain our models. These techniques can be used in areas where people do not deal with the actual working of a ML model but only require the outputs of ML processes

scholarly journals A Comparative Analysis of Machine Learning Algorithms to Predict Alzheimer’s Disease

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Morshedul Bari Antor ◽  
A. H. M. Shafayet Jamil ◽  
Maliha Mamtaz ◽  
Mohammad Monirujjaman Khan ◽  
Sultan Aljahdali ◽  
...  
Keyword(s):  
Machine Learning ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Support Vector Machine ◽  
Machine Learning Algorithms ◽  
Learning System ◽  
Fine Tuning ◽  
Support Vector ◽  
Learning Models ◽  
Machine Learning Models

Alzheimer’s disease has been one of the major concerns recently. Around 45 million people are suffering from this disease. Alzheimer’s is a degenerative brain disease with an unspecified cause and pathogenesis which primarily affects older people. The main cause of Alzheimer’s disease is Dementia, which progressively damages the brain cells. People lost their thinking ability, reading ability, and many more from this disease. A machine learning system can reduce this problem by predicting the disease. The main aim is to recognize Dementia among various patients. This paper represents the result and analysis regarding detecting Dementia from various machine learning models. The Open Access Series of Imaging Studies (OASIS) dataset has been used for the development of the system. The dataset is small, but it has some significant values. The dataset has been analyzed and applied in several machine learning models. Support vector machine, logistic regression, decision tree, and random forest have been used for prediction. First, the system has been run without fine-tuning and then with fine-tuning. Comparing the results, it is found that the support vector machine provides the best results among the models. It has the best accuracy in detecting Dementia among numerous patients. The system is simple and can easily help people by detecting Dementia among them.

Utilizing Blockchain Technology in Social Media Bot Identification

2020 ◽  
Author(s):  
Shreya Reddy ◽  
Lisa Ewen ◽  
Pankti Patel ◽  
Prerak Patel ◽  
Ankit Kundal ◽  
...  
Keyword(s):  
Machine Learning ◽  
Social Media ◽  
Gold Standard ◽  
The Internet ◽  
Learning Models ◽  
Current Time ◽  
Machine Learning Methods ◽  
Blockchain Technology ◽  
Modern Age ◽  
Machine Learning Models

<p>As bots become more prevalent and smarter in the modern age of the internet, it becomes ever more important that they be identified and removed. Recent research has dictated that machine learning methods are accurate and the gold standard of bot identification on social media. Unfortunately, machine learning models do not come without their negative aspects such as lengthy training times, difficult feature selection, and overwhelming pre-processing tasks. To overcome these difficulties, we are proposing a blockchain framework for bot identification. At the current time, it is unknown how this method will perform, but it serves to prove the existence of an overwhelming gap of research under this area.<i></i></p>

Document Preprocessing with TF-IDF to Improve the Polarity Classification Performance of Unstructured Sentiment Analysis

2020 ◽  
pp. 235-242
Author(s):  
Farrikh Alzami ◽  
Erika Devi Udayanti ◽  
Dwi Puji Prabowo ◽  
Rama Aria Megantara
Keyword(s):  
Machine Learning ◽  
Feature Extraction ◽  
Random Forest ◽  
Sentiment Analysis ◽  
Classification Performance ◽  
Document Preparation ◽  
Learning Models ◽  
Polarity Classification ◽  
Negative Sentiment ◽  
Machine Learning Models

Sentiment analysis in terms of polarity classification is very important in everyday life, with the existence of polarity, many people can find out whether the respected document has positive or negative sentiment so that it can help in choosing and making decisions. Sentiment analysis usually done manually. Therefore, an automatic sentiment analysis classification process is needed. However, it is rare to find studies that discuss extraction features and which learning models are suitable for unstructured sentiment analysis types with the Amazon food review case. This research explores some extraction features such as Word Bags, TF-IDF, Word2Vector, as well as a combination of TF-IDF and Word2Vector with several machine learning models such as Random Forest, SVM, KNN and Naïve Bayes to find out a combination of feature extraction and learning models that can help add variety to the analysis of polarity sentiments. By assisting with document preparation such as html tags and punctuation and special characters, using snowball stemming, TF-IDF results obtained with SVM are suitable for obtaining a polarity classification in unstructured sentiment analysis for the case of Amazon food review with a performance result of 87,3 percent.

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