scholarly journals Manual Annotation Studio (MAS): a collaborative platform for manual functional annotation of viral and microbial genomes

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Matthew R. Lueder ◽  
Regina Z. Cer ◽  
Miles Patrick ◽  
Logan J. Voegtly ◽  
Kyle A. Long ◽  
...  

Abstract Background Functional genome annotation is the process of labelling functional genomic regions with descriptive information. Manual curation can produce higher quality genome annotations than fully automated methods. Manual annotation efforts are time-consuming and complex; however, software can help reduce these drawbacks. Results We created Manual Annotation Studio (MAS) to improve the efficiency of the process of manual functional annotation prokaryotic and viral genomes. MAS allows users to upload unannotated genomes, provides an interface to edit and upload annotations, tracks annotation history and progress, and saves data to a relational database. MAS provides users with pertinent information through a simple point and click interface to execute and visualize results for multiple homology search tools (blastp, rpsblast, and HHsearch) against multiple databases (Swiss-Prot, nr, CDD, PDB, and an internally generated database). MAS was designed to accept connections over the local area network (LAN) of a lab or organization so multiple users can access it simultaneously. MAS can take advantage of high-performance computing (HPC) clusters by interfacing with SGE or SLURM and data can be exported from MAS in a variety of formats (FASTA, GenBank, GFF, and excel). Conclusions MAS streamlines and provides structure to manual functional annotation projects. MAS enhances the ability of users to generate, interpret, and compare results from multiple tools. The structure that MAS provides can improve project organization and reduce annotation errors. MAS is ideal for team-based annotation projects because it facilitates collaboration.

2014 ◽  
Vol 494-495 ◽  
pp. 1373-1376
Author(s):  
Yan Hui Cheng

This paper is based on the expansion of the CAN bus interface on ARM so that the embedded CNC system to achieve network, and display their respective advantages of field bus technology and embedded technology, so that to set up local area network embedded NC system model. The CNC system designed in this paper has characteristic as follows: high integration, flexible structure, good expansibility and the high performance-to-price ratio and so on.


2013 ◽  
Vol 198 ◽  
pp. 260-265 ◽  
Author(s):  
Bartosz Brzozowski ◽  
Wiesław Sobieraj ◽  
Konrad Wojtowicz

During last few years avionics system research platform was invented at the Military University of Technology. This modular simulator allows user to design and verify avionics system software using hardware-in-the-loop technique. Mathematical model of an airplane under tests is implemented on a high-performance computer which response to all control signals and environmental disturbances. Environment is simulated on a separate computer which can also visualize orientation and movement of the airplane. Plane structure and aerodynamic features as well as control data can be modified accordingly to user needs. The third PC is used as an interface unit between research platform and main computational unit of the avionics system. This device can send and receive information in real-time using various data protocols and interfaces depending on sensors and actuators that are planned to be used in real system. Those three computers work in a local area network and exchange data using Gigabit Ethernet standard. Possibility to simulate behavior of an UAV controlled by the developed avionics system implemented on an embedded computer working in hardware-in-the-loop mode on the platform, allows software developer to debug any part of the application in various environment conditions very close to reality. Research platform gives also the possibility to modify algorithm and adjust its parameters in real-time to verify suitability of the implemented avionics system software for the particular UAV. The avionics system software developed using this simulation method minimize expensive in-flight tests and assure failsafe performance after first successful flight


2015 ◽  
Vol 8 (2) ◽  
pp. 309-317 ◽  
Author(s):  
Raefat Jalila El Bakouchi ◽  
Marc Brunet ◽  
Tchanguiz Razban ◽  
Abdelilah Ghammaz

This paper presents a multiple-input and multiple-output dual-element planar inverted-F antenna (PIFA) array for broadband operation covering the HIgh PERformance radio Local Area Network/2 (5.2 GHz/5.6 GHz), Wireless Local Area Network (5.2 GHz/5.8 GHz), and the Worldwide Interoperability for Microwave Access (5.5 GHz) bands for the compact wireless communication devices. The antenna dimension is reduced substantially with a miniature ground plane. The PIFA array provides a large bandwidth (670 MHz) and a high isolation between its ports less than −26 dB. The proposed antenna has been analyzed and designed with Ansoft HFSS v.11. Then a prototype was fabricated and tested for its performance in terms of bandwidth, S-parameters, and radiation pattern. A parametric study is made to analyze the effect of different PIFA parameters on the operating frequency and the S-parameters. The diversity performances are evaluated using computer simulation technology microwave studio (CSTMWS). The broadband performance and the high isolation are achieved in both simulation and measurement.


2015 ◽  
Vol 8 (2) ◽  
pp. 363-368 ◽  
Author(s):  
Raghupatruni Venkatsiva Ram Krishna ◽  
Raj Kumar ◽  
Nagendra Kushwaha

In this paper, a microstrip fed, L-shape slot antenna for dual polarization is proposed. The two arms of the slot generate electric fields of orthogonal polarizations. By properly sectioning the slot and the feed line, ultra wideband (UWB) behavior is obtained. The measured impedance bandwidth (S11< −10 dB) is more than 8.6 GHz (112%) and 8.2 GHz (104%) for Port 1 and Port 2, respectively. The measured isolation is better than 25 dB over most of the band. The aperture field distribution justifies the dual polarized nature. A modified version which implements a band-notch over 5.1–5.85 GHz wireless local area network (WLAN) band is also presented. With a compact, single substrate design, the antenna can be useful in MIMO transmission systems, polarimetric UWB radar, high performance microwave imaging, and other future wireless communications devices.


Sensors ◽  
2019 ◽  
Vol 19 (8) ◽  
pp. 1880 ◽  
Author(s):  
Kristián Košťál ◽  
Rastislav Bencel ◽  
Michal Ries ◽  
Peter Trúchly ◽  
Ivan Kotuliak

Wireless Local Area Network (WLAN) infrastructure is a dominant technology for direct access to the Internet and for cellular mobile data traffic offloading to WLANs. Additionally, the enterprise infrastructure can be used to provide functionality for the Internet of Things and Machine to Machine scenarios. This work is focused on improvements of radio resources control scalability similar to mobile networks via handover between cells. We introduce an improved IEEE 802.11 architecture utilizing Software-Defined Networks (SDNs). The proposed architecture allows communications during device movements without losing a quality of service (QoS). The fast seamless handover with QoS enables efficient usage of radio resources in large networks. Our improvements consist of integrating wireless management to OpenFlow protocol, separating encryption and decryption from an access point. In parallel, this feature as a side effect unloads processing at the Access Points (APs). Finally, the functionality of architecture design and scalability was proven by Colored Petri Nets (CPNs). The second proof of our concept was performed on two scenarios. The first scenario was applied to a delay sensitive use case. The second scenario considers a network congestion in real world conditions. Client’s mobility was integrated into both scenarios. The design was developed to demonstrate SDN WLAN architecture efficiency.


Electronics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 142
Author(s):  
Min-Hang Weng ◽  
Chun-Yueh Huang ◽  
Shi-Wei Dai ◽  
Ru-Yuan Yang

In this paper, we present a dual-band microstrip bandpass filter (BPF) with an improved stopband, which was constructed by a quad-mode stub-loaded resonator (SLR). Since the SLR is able to produce multiresonance within a single unit, the area saving is significant. The proposed quad-mode SLR was implemented by two stubs allocated at symmetry places, thus the even-/odd-mode can be applied to analysis the resonance. Moreover, to shift the spurious passband, the step impedance structure was applied to shift the harmonic resonance to the higher frequency. Design procedure for high performance dual-band BPF is proposed, and filter examples were designed for wireless local area network (WLAN) of 2.4/5.2 GHz. The measured insertion losses, return losses and fractional bandwidths (FBW) are 1.43 dB, 10 dB, and 14.8% at 2.4 GHz and 1.34 dB, 10 dB, and 12.9% at 5.2 GHz. Moreover, by applying two quarter-wavelength stubs on the input/output ports, the passband selectivity with an isolation of 40 dB can be achieved. The simulation and measurement have a close match, verifying the design concept.


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