scholarly journals High prevalence of t895 and t9364 spa types of methicillin-resistant Staphylococcus aureus in a tertiary-care hospital in Mexico: different lineages of clonal complex 5

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
C. Negrete-González ◽  
E. Turrubiartes-Martínez ◽  
O. G. Galicia-Cruz ◽  
D. E. Noyola ◽  
G. Martínez-Aguilar ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Clonal Complex ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Methicillin Resistant ◽  
High Prevalence ◽  
Spa Types

scholarly journals High prevalence of t895 and t9364 spa types of methicillin-resistant Staphylococcus aureus in a tertiary-care hospital in México: Different lineages of Clonal Complex 5

2020 ◽  
Author(s):  
C Negrete-González ◽  
E Turrubiartes-Martínez ◽  
OG Galicia-Cruz ◽  
DE Noyola ◽  
G Martínez-Aguilar ◽  
...  
Keyword(s):  
New York ◽  
Staphylococcus Aureus ◽  
Clonal Complex ◽  
Tertiary Care Hospital ◽  
Sccmec Type ◽  
Tertiary Care ◽  
Molecular Characteristics ◽  
Care Hospital ◽  
Methicillin Resistant ◽  
Spa Types

Abstract BACKGROUND Staphylococcus aureus is a leading cause of broad-spectrum infections both, in the community and within the healthcare settings. The methicillin-resistant Staphylococcus aureus (MRSA) variant has became a global issue of public health. The aim of this study was to examine the clinical and molecular characteristics of Staphylococcus aureus isolates and to define the population structure and distribution of major MRSA clones present in a tertiary-care hospital in Mexico. RESULTS From April 2017 to April 2018, 191 isolates of Staphylococcus aureus were collected. The frequency of MRSA was 26.7%, these strains exhibited resistance to clindamycin (85.3%), erythromycin (86.2%), levofloxacin (80.3%), and ciprofloxacin (86.3%). The majority of MRSA strains harbored the SCCmec type II (39/51); the t895 (29/51) and t9364 (6/51) were the most common spa types in both, hospital-associated MRSA and community associated MRSA isolates. The clones ST5-MRSA-II-t895 (New York /Japan clone) and ST1011-MRSA-II-t9364 (New York /Japan-Mexican Variant clone) were the most frequent. Finally, different lineages of Clonal Complex 5 (90.6%) and Clonal Complex 8 (9.1%) were identified in this study. CONCLUSION Our study provides valuable information about the epidemiology of MRSA in a city of the central region of Mexico, and this is the first report on the association between the t895 and t9364 spa types and the ST5 and ST1011 lineages, respectively.

scholarly journals METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS CARRIAGE AMONG HEALTH-CARE PROFESSIONALS OF A TERTIARY CARE HOSPITAL

2018 ◽  
Vol 11 (3) ◽  
pp. 346
Author(s):  
Latha T ◽  
Anil K Bhat ◽  
Manjunatha Hande H ◽  
Chiranjay Mukhopadyay ◽  
Elsa Sanatombi Devi ◽  
...  
Keyword(s):  
Health Care ◽  
Staphylococcus Aureus ◽  
Health Care Professionals ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Carrier Status ◽  
Care Hospital ◽  
Methicillin Resistant ◽  
Orthopedic Patients

 Objective: The aim of this study was to find the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) carrier status in anterior nares and hands of health-care professionals working in orthopedic wards of a tertiary care hospital and to decolonize them to reduce spread of MRSA to their patients.Methods: The study was conducted in a super specialty, tertiary care teaching hospital. The samples were collected from anterior nares, palm, web spaces, and fingertips of 140 health-care professionals (48 doctors, 74 nurses, and 18 technicians) working in orthopedic wards using sterile pre-moistened swabs. MRSA carrier status was identified by Kirby-Bauer disc diffusion method.Result: Most (76.4%) of the health-care professionals were <30 years of age and 51% were male. MRSA in anterior nares of doctors was 4.3%, nurses 1.4%, and technicians 0.7% and none had MRSA in their hands. Methicillin-sensitive Staphylococcus aureus (MSSA) growth was more among nurses (nurses - 5.7%, doctors - 2.1%, and technicians - 1.4%) in anterior nares. In addition, 1.4% nurses’ hands were colonized with MSSA. Both MRSA and MSSA carriers were decolonized effectively and repeat sampling showed no growth.Conclusion: Health-care professionals have a greater chance of transmitting MRSA to patients and orthopedic patients are more susceptible for infection. Although MRSA carrier status was not very high among orthopedic health-care professionals compared to previous studies, it cannot be ignored. Nasal mupirocin and bath with chlorhexidine soap were effective in decolonization. Periodic screening and treatment of colonizers would help in elimination of MRSA carriage.

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