scholarly journals Comorbid early esophageal cancer and Gongylonema pulchrum infection: a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qiaozhi Zhou ◽  
Yongqiu Wei ◽  
Huihong Zhai ◽  
Shaogang Li ◽  
Rui Xu ◽  
...  

Abstract Background Gongylonema pulchrum is a zoonotic parasite rarely found in humans. To date, there have been no reports on the carcinogenic properties of G. pulchrum, and there are few reports overall on the relationship between esophageal cancer and parasites. Case presentation This report describes the first case of esophageal gongylonemiasis coexisting with early esophageal cancer. The patient had no high-risk factors for esophageal cancer, such as smoking, flushing after drinking, or tumor history. We speculate the existence of unknown links between esophageal cancer and parasitic infection in this patient. Discussion and conclusions We report the first case of a human presenting both esophageal G. pulchrum infection and esophageal squamous cell carcinoma with the hope that it may provide evidence for a new hypothesis of tumorigenesis.

2021 ◽  
Author(s):  
Dali Long ◽  
Yuhui Wang ◽  
Jinlong Wang ◽  
Sijie Mu ◽  
Li Chen ◽  
...  

Abstract Background Klebsiella pneumoniae infection leads to significant concerns because of its varied manifestation and resultant mortality. While recent genetic structure analysis reveals that the higher virulence and mortality could be from its subspecies rather than Klebsiella pneumoniae. However, which is often misdiagnosed and underestimated in clinic because it’s difficult to distinguish Klebsiella pneumoniae from its subspecies using classic clinical examinations. This case study is the first in clinic to report the fast and fatal effect of Klebsiella subspecies, and serve as reference for doctors diagnosing similar diseases. Case presentation A 52-years male patient was admitted to hospital due to unknown high fever. All examinations excluded the viruses, fungi, mycoplasma/chlamydia and parasitic infection. Classic bacterial culture revealed the klebsiella pneumonia, however sensitive antibacterial adheres to drug susceptibility results failed to improve patient’s symptoms. His condition worsened and rapidly entered sepsis and subsequent sepsis shock, died within 72 hours of symptom onset. The PMseq-DNA Pro High throughput gene detection was acquired on second day after death revealing the mixed infection of klebsiella variicola and klebsiella pneumoniae. Clinic evidences suggested that Klebsiella variicola rather than klebsiella pneumoniae contributed to patient’s poor prognosis. Conclusions: This is the first case reported that patient died from klebsiella subspecies infection within short period of time. Which suggests that we should be alert to the clinical hazards and fatal effect of klebsiella subspecies. Classic method is limited in guiding the anti-infection therapy for complex cases, early genetic detection should be recommended in the diagnosis and management of complex infection.


1996 ◽  
Vol 47 (2) ◽  
pp. 150-154 ◽  
Author(s):  
Hiroyasu Makuuchi ◽  
Hideo Shimada ◽  
Kyoichi Mizutani ◽  
Osamu Chino ◽  
Takao Machimura ◽  
...  

2017 ◽  
pp. 119-124
Author(s):  

Introduction: Intestinal parasite infections werecommonintropical country such as Vietnam. Having good knowledge of parasitic infectious prevention and changing risk behaviors can decrease the infection rate. Objective: To evaluate the parasitic infectious rate in Vinh Thai community before and after being health education and the changing of knowledge of parasitic infectious prevention and risk behaviors. Materials and methods: 60 households in Vinh Thai commune were interviewed their knowledge of parasitic infectious prevention and examined intestinal parasite infection by Kato technique and then trained the knowledge of parasitic infectious prevention. The interview and examination parasite infectiousrate were carried out after 6 months to evaluating their knowledge. Result: Before health education, the rate of intestinal parasite infection was 17.4% with the prevalence of Ascaris lumbricoides, hookworm, whipworm, pinworm, small fluke worm and co-infection with A. lumbricoides - whipworm, hookworm-whipworm were 0.1%; 8.0%; 5.8%; 0.6%; 0.3%; 1.2% and 3.0% respectively. Six months later the rate of intestinal parasite infection was decreased in 12.6% even though not statistical significantly. However, there were no case of small fluke worm and co-infection with hookworm-whipworm. Receiving health education, their knowledge of parasitic infectious prevention was higher significantly but their risk behaviors were not changed so much. Conclusion: Health education can change the rate of parasite infection with higher knowledge of parasitic infectious prevention but it was necessary continuous study to change the risk behaviors. Key words: intestinal parasite, health education


2017 ◽  
Vol 63 (4) ◽  
pp. 660-665
Author(s):  
Yelena Tyuryaeva

The article is devoted to various aspects of the use of intraluminal brachytherapy (IB) in treatment for esophageal cancer (EC). A critical review of the use of IB as a component of combined radiotherapy/chemoradiotherapy in neoadjuvant treatment regimens, for definitive CRT, as well as in palliative treatment of non-operable tumors of this localization is given. The contradictory data on the effectiveness of brachytherapy with locally distributed, inoperable EC are summarized. A separate section relates to the prospects for incorporating brachytherapy into combined treatment of early esophageal cancer. Carried out analysis testifies to the necessity of standardization of summary and daily doses of irradiation depending on the indications to the IB.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Karen Bitton ◽  
J.-L. Bacquet ◽  
F. Amoroso ◽  
S. Mrejen ◽  
M. Paques ◽  
...  

Abstract Background Pathologic myopia is a major cause of visual impairment and blindness. Case presentation We report a case of an immediate post partum macular subretinal bleeding observed in a highly myopic patient. A 30-years-old woman presented two days after childbirth for sudden loss of vision in her right eye. Multimodal imaging showed macular hemorrhage masking a subtle yellowish linear lesion corresponding to lacker crack. Due to the lack of evidence for choroidal neovascularization, a simple clinical and imaging monitoring was recommended. Six weeks later, we noted an improvement in her best-corrected visual acuity and a decreased in size of the macular hemorrhage. Conclusions This is the first case reporting a macular subretinal bleeding on macular lacquer cracks in a highly myopic patient in immediate post partum. Valsalva maneuver associated with vaginal delivery could explain the occurrence of the hemorrhage associated with lacquer crack. However, natural history of pathological myopia could not be excluded.


2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Tiffany A. Perkins ◽  
Alberic Rogman ◽  
Murali K. Ankem

Abstract Background Emphysematous pyelonephritis (EPN) with gas in the inferior vena cava (IVC) is a rare presentation and to our knowledge, this is the first case report in the urologic literature. Case presentation A 35-Year-old obese diabetic Hispanic female presented to the emergency room with a clinical picture of septic shock. Prompt computerized tomography scan revealed EPN with gas throughout the right renal parenchyma and extending to the right renal vein, IVC, and pulmonary artery. She died before surgical intervention Conclusion This case demonstrates that patients presenting with severe EPN have a high mortality risk and providers should acknowledge that septic shock, endogenous air emboli, or a combination of both could result in cardiovascular collapse and sudden death.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Atsushi Takeno ◽  
Toru Masuzawa ◽  
Shinsuke Katsuyama ◽  
Kohei Murakami ◽  
Kenji Kawai ◽  
...  

Abstract Background The robotic system has been applied in the treatment of gastric cancer (GC), and the procedure has been found to be safe and feasible. Situs inversus totalis (SIT) is a relatively rare autosomal recessive congenital anomaly. We successfully performed robot-assisted proximal gastrectomy (RAPG) and handsewn double-flap esophagogastrostomy for GC in a patient with SIT. Case presentation A 71-year-old woman was referred to us with an asymptomatic ulcerative lesion in the upper body of the stomach. Computed tomography revealed that she had SIT. She was diagnosed with cT1bN0M0, cStageIA gastric cancer. RAPG with lymph node dissection and handsewn double-flap esophagogastrostomy was performed. Robotic surgery enabled the surgeon to perform the surgery without changing his position and experiencing any confusion resulting from the patient’s reversed anatomy. It took 448 min, and no intraoperative complications occurred. Her postoperative course was uneventful; she was discharged on postoperative day 10. The final pathologic report showed pT1b1N0M0, pStage IA. Conclusions This is the first case describing RAPG with handsewn double-flap esophagogastrostomy for a SIT patient with early GC.


2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Anupam Nanda ◽  
Rajinder Nanda ◽  
Seema Thakur ◽  
Tej Prakash Gupta ◽  
Sudhir Jain ◽  
...  

AbstractObjectivesLung tissue choristoma is a very rare disorder where mature lung tissues develop in the site not normal to the lung.Case presentationWe hereby report a first case of fetal pulmonary choristoma in a 23–24 weeks fetus where antenatal ultrasound showed a mass in posterior fossa with severe ventriculomegaly. The mass extended inferiorly in cervical spinal column and thereafter extended in the skin over the back of fetus. Fetal autopsy confirmed these findings. Pathologic findings showed mature lung tissues with bronchi, bronchioles, and alveoli. Clinical exome sequencing showed normal results.ConclusionsWe describe the antenatal ultrasound, fetal autopsy and pathologic findings of an intracranial and cutaneous pulmonary choristoma.


2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Nabil Nabil Moohialdin ◽  
Ahmad Shamsodini ◽  
Steven K. Wilson ◽  
Osama Abdeljaleel ◽  
Ibrahim Alnadhari ◽  
...  

Abstract Background Infection after the penile prosthesis can be devastating to both the patient and surgeon with various complications and consequences. After introduction of antibiotic-coated implants, the rate of infection has dramatically decreased, but still we see uncommon organisms causing infection. We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. To our knowledge, this is the first reported case of brucellosis penile prosthesis infection. Case presentation We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. A 75-year-old, diabetic male patient presented with penile prosthesis infection 5 months post-penile exchange surgery due to mechanical malfunctioning of 2-piece penile prosthesis which was inserted 11 years ago. The initial treatment with broad spectrum antibiotics did not subside the infection. After diagnosis of brucellosis, the antibiotic was changed to anti-brucellosis (Rifampicin + Tetracycline). The patient improved dramatically and was discharged home with smooth follow-up course. Conclusion Brucellosis can cause infection of penile prosthesis and can be treated with anti-brucellosis antibiotics without necessitating surgical intervention and removal of prosthesis.


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