scholarly journals Ultrasonographic length of morphologically-normal kidneys in children presented to a premier tertiary healthcare setting of Sri Lanka

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
W. D. Duminda ◽  
K. G. Pathirana ◽  
M. U. J. Fernando ◽  
R. A. N. K. K. Samarasinghe ◽  
W. D. H. A. Ananda ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Healthcare Setting ◽  
Tertiary Healthcare

Epidemiological features of nosocomial Klebsiella pneumoniae: virulence and resistance determinants

2021 ◽  
Author(s):  
Mai M Zafer ◽  
Maha M El Bastawisie ◽  
Mona Wassef ◽  
Amira FA Hussein ◽  
Mohammed A Ramadan
Keyword(s):  
Klebsiella Pneumoniae ◽  
Resistance Genes ◽  
Antibiotic Resistance Genes ◽  
Pcr Amplification ◽  
Virulence Gene ◽  
Healthcare Setting ◽  
Virulence Determinants ◽  
Tertiary Healthcare ◽  
Insight Into ◽  
Common Sequence

Aim: The authors aimed to examine antibiotic resistance genes and representative virulence determinants among 100 Klebsiella pneumoniae isolates with an emphasis on capsular serotypes and clonality of some of the isolates. Methods: PCR amplification of ( rmpA, rmpA2, iutA, iroN and IncHI1B plasmid) and (NDM, OXA-48, KPC, CTX-M-15, VIM, IMP, SPM) was conducted. Wzi sequencing and multilocus sequence typing (MLST) were performed. Results: K2 was the only detected serotype in the authors' collection. RMPA2 was the most common capsule-associated virulence gene detected. All studied isolates harbored OXA-48-like (100%) and NDM (43%) (n = 43). ST147 was the most common sequence type. Conclusion: This work provides insight into the evolution of the coexistence of virulence and resistance genes in a tertiary healthcare setting in Cairo, Egypt.

scholarly journals ‘Modified STOPP-START criteria for Sri Lanka’; translating to a resource limited healthcare setting by Delphi consensus

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
N. R. Samaranayake ◽  
A. Balasuriya ◽  
G. H. Fernando ◽  
D. Samaraweera ◽  
L. G. T. Shanika ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Screening Tool ◽  
Treatment Guidelines ◽  
Clinical Information ◽  
Complete Removal ◽  
Healthcare Setting ◽  
Delphi Consensus ◽  
Multi Centre Study ◽  
Resource Limited ◽  
Start Criteria

Abstract Background ‘Screening tool of older people’s prescriptions (STOPP) and screening tool to alert to right treatment (START)’ criteria is a useful tool to assess the appropriateness of medicines among older adults. However, the original STOPP/START criteria developed in the West, may not be directly applicable to resource limited healthcare settings like Sri Lanka. Hence, we aimed to modify STOPP/START criteria (Version 2) to suit Sri Lanka. Method Two investigators (a clinical pharmacologist and a pharmacist) reviewed and flagged criteria that were unfeasible to Sri Lanka based on their previous research experiences on using STOPP/START version 1. A Delphi consensus methodology was conducted among six experts, including geriatricians, clinical pharmacologists, physicians and a pharmacist, to review and assess each criterion (including the ones flagged by the researchers) for suitability to Sri Lanka. Results Two Delphi validation rounds were conducted. A final meeting was held with the participation of all experts to resolve disagreements and to establish 100% consensus. The expert panel agreed on a list of 105 criteria, including 70 STOPP and 35 START criteria, indicating an 8% reduction in criteria compared to the original version. Modifications included complete removal (n = 11), re-wording (n = 25), splitting (n = 1) of original criteria and adding a new criterion (n = 1). Main reasons for modifications were unavailability of some medicines in the country, unavailability or inaccessibility of specific clinical information required for assessment of criteria, and adherence to treatment guidelines commonly used in the country. Conclusion A list of ‘Modified STOPP/START criteria for Sri Lanka’ was developed. These criteria are currently being validated through a multi-centre study.

Whole-Genome Sequencing of Presumptive MDR-TB Isolates from a Tertiary Healthcare Setting in Mumbai

2021 ◽  
Author(s):  
Amrutraj Zade ◽  
Sanchi Shah ◽  
Nilma Hirani ◽  
Kiran Kondabagil ◽  
Ameeta Joshi ◽  
...  
Keyword(s):  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Healthcare Setting ◽  
Whole Genome ◽  
Mdr Tb ◽  
Tertiary Healthcare

The effect of unfractionated heparin on the haemostatic system of children admitted to a tertiary healthcare setting

Pathology ◽  
2010 ◽  
Vol 42 ◽  
pp. S70 ◽  
Author(s):  
M. Hiremath ◽  
V. Ignjatovic ◽  
F. Newall ◽  
R. Summerhayes ◽  
P. Monagle
Keyword(s):  
Unfractionated Heparin ◽  
Healthcare Setting ◽  
Tertiary Healthcare

scholarly journals Predictors of poor glycemic control among patients with type 2 diabetes on follow-up care at a tertiary healthcare setting in Ethiopia

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Gebre Teklemariam Demoz ◽  
Alem Gebremariam ◽  
Helen Yifter ◽  
Minyahil Alebachew ◽  
Yirga Legesse Niriayo ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycemic Control ◽  
Healthcare Setting ◽  
Poor Glycemic Control ◽  
Follow Up Care ◽  
Tertiary Healthcare

scholarly journals P258 Rates of admission of acute IBD flares during the COVID-19 pandemic in a tertiary healthcare setting

2021 ◽  
Vol 15 (Supplement_1) ◽  
pp. S293-S294
Author(s):  
K Hazel ◽  
E Glynn ◽  
K Boland ◽  
A O’Toole
Keyword(s):  
Air Pollution ◽  
Hospital Admissions ◽  
Early Stage ◽  
Healthcare Setting ◽  
Electronic Patient Records ◽  
Patient Demographics ◽  
Related Risk ◽  
Tertiary Healthcare ◽  
Inflammatory Bowel ◽  
The Impact

Abstract Background Environmental tiggers are thought to contribute to Inflammatory Bowel Disease flares. The COVID-19 pandemic and resulting lockdown led to an emphasis on outpatient care, fewer presentations to hospital for non-COVID-19-related illnesses, changes in work practices and a reduction in air pollution. Our aim was to determine the impact of these changes on hospital admissions with acute IBD flares. Methods The hospital in-patient enquiry (HIPE) department provided records of all patients admitted with acute IBD flares during the first Irish lockdown from March to May 2020 and for the corresponding period in 2017, 2018 and 2019. Electronic patient records were used to assess patient demographics, biochemical markers, imaging, medication use and outcome. Results 101 patients were admitted with an acute IBD flare. This was a marked reduction when compared to the corresponding period in the previous three years (p<0.0001). Despite the rates of admission decreasing in this period, rates of colectomy were significantly increased (p<0.0001). (Table 1). Conclusion We demonstrated a significant decrease in hospital admissions for acute IBD flares during the first wave of the pandemic. We postulate that changes in environmental triggers of IBD such as working from home and reduced stress levels in addition to reduced air pollution may account for this reduction. The increased rate of colectomy likely reflects a more severe presentation of IBD and patients’ reluctance to attend the hospital at an early stage in their disease flare as well as non-adherence to prescribed IBD therapies due to a perceived COVID-19-related risk.

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