scholarly journals Current trends and geographical differences in therapeutic profile and outcomes of COVID-19 among pregnant women - a systematic review and meta-analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Pallavi Dubey ◽  
Bhaskar Thakur ◽  
Sireesha Reddy ◽  
Carla A. Martinez ◽  
Md Nurunnabi ◽  
...  

Abstract Background Coronavirus disease (COVID-19) has been associated with adverse pregnancy outcomes. Due to the lack of effective treatments for COVID-19, it becomes imperative to assess the geographical differences and trends in the current clinical care and outcomes of COVID-19 in pregnant women. Methods A PubMed search was performed to screen articles reporting therapeutics and outcomes of confirmed COVID-19 in pregnant women prior to August 27, 2020. We performed searches, quality assessments of eligible studies, extracted and reported data according to PRISMA guidelines. Meta-analyses and cumulative meta-analyses of proportions were performed for estimating each outcome and their pattern over time respectively. Results One thousand two hundred thirty nine pregnant women with COVID-19 from 66 studies were analyzed. In case series analysis reflecting average-risk patients, the proportion of oxygen support, antibiotics, antivirals, and plasma therapy administration except for hydroxychloroquine was substantially higher in Asian studies (55, 78, 80, 6, and 0%) compared to the US (7, 1, 12, 0, and 7%) or European (33, 12, 14, 1, and 26%) studies, respectively. The highest preterm birth and the average length of hospital stay (35%, 11.9 days) were estimated in Asian studies compared to the US studies (13%, 9.4 days) and European studies (29%, 7.3 days), respectively. Even in case reports reflecting severe cases, the use of antivirals and antibiotics was higher in Asian studies compared to the US, Latin American, and European studies. A significant decline in the use of most therapeutics along with adverse outcomes of COVID-19 in pregnant women was observed. Conclusions Geographical differences in therapeutic practice of COVID-19 were observed with differential rates of maternal and clinical outcomes. Minimizing the use of some therapeutics particularly antibiotics, antivirals, oxygen therapy, immunosuppressants, and hydroxychloroquine by risk stratification and careful consideration may further improve maternal and clinical outcomes.

Author(s):  
Sally-Ann Treharne

Reagan and Thatcher’s Special Relationship offers a unique insight into one of the most controversial political relationships in recent history. An insightful and original study, it provides a new regionally focused approach to the study of Anglo-American relations. The Falklands War, the US invasion of Grenada, the Anglo-Guatemalan dispute over Belize and the US involvement in Nicaragua are vividly reconstructed as Latin American crises that threatened to overwhelm a renewal in US-UK relations in the 1980s. Reagan and Thatcher’s efforts to normalise relations, both during and after the crises, reveal a mutual desire to strengthen Anglo-American ties and to safeguard individual foreign policy objectives whilst cultivating a close personal and political bond that was to last well beyond their terms in office. This ground-breaking reappraisal analyses pivotal moments in their shared history by drawing on the extensive analysis of recently declassified documents while elite interviews reveal candid recollections by key protagonists providing an alternative vantage point from which to assess the contentious ‘Special Relationship’. Sally-Ann Treharne offers a compelling look into the role personal diplomacy played in overcoming obstacles to Anglo-American relations emanating from the turbulent Latin American region in the final years of the Cold War.


2018 ◽  
Vol 33 ◽  
Author(s):  
Guilherme Casarões

The institutional framework of Latin American integration saw a period of intense transformation in the 2000s, with the death of the ambitious project of the Free Trade Area of the Americas (FTAA), spearheaded by the United States, and the birth of two new institutions, the Union of South American Nations (UNASUR) and the Community of Latin American and Caribbean States (CELAC). This article offers a historical reconstruction of regional integration structures in the 2000s, with emphasis on the fault lines between Brazil, Venezuela and the US, and how they have shaped the institutional order across the hemisphere. We argue that the shaping of UNASUR and CELAC, launched respectively in 2007 and 2010, is the outcome of three complex processes: (1) Brazil’s struggle to strengthen Mercosur by acting more decisively as a regional paymaster; (2) Washington’s selective engagement with some key regional players, notably Colombia, and (3) Venezuela’s construction of an alternative integration model through the Bolivarian Alliance (ALBA) and oil diplomacy. If UNASUR corresponded to Brazil’s strategy to neutralize the growing role of Caracas in South America and to break apart the emerging alliance between Venezuela, Argentina, and Bolivia, CELAC was at the same time a means to keep the US away from regional decisions, and to weaken the Caracas-Havana axis that sustained ALBA.


Author(s):  
Jeffrey Lawrence

This chapter turns from a historical account of the development of the US literature of experience and the Latin American literature of reading to a textual analysis of the US and Latin American historical novel. Hemispheric/inter-American scholars often cite William Faulkner’s Absalom, Absalom! (1936), Gabriel García Márquez’s One Hundred Years of Solitude (1967), and Toni Morrison’s Song of Solomon (1977) as exemplifying instances of literary borrowing across the North–South divide. As I demonstrate, however, each of the later texts also realigns its predecessor’s historical imaginary according to the dominant logics of the US and Latin American literary fields. Whereas the American works foreground experiential models of reconstructing the past and conveying knowledge across generations, García Márquez’s Latin American novel presents reading as the fundamental mode of comprehending and transmitting history.


Author(s):  
Jeffrey Lawrence

This chapter focuses on a paradigmatic misencounter between an American experiencer and a Latin American reader. Examining an implicit debate about the sources of Walt Whitman’s poetry and vision of the Americas, I argue that Waldo Frank, one of the twentieth century’s main literary ambassadors from the US to Latin America, positioned Whitman as the representative US writer whose antibookish experiential aesthetics could serve as a model for “American” writers both in the North and in the South. I show how Frank’s framework provided a foil for Borges’s idiosyncratic view that Whitman’s poetry about America derived entirely from his readings of European and US writers. Although much of the best scholarship on Whitman’s reception in Latin America has concentrated on poets like José Martí and Pablo Neruda, who adapted Whitman’s naturalism, I contend that Borges’s iconoclastic portrait of Whitman as a reader profoundly influenced a range of anti-experiential literary theories and practices in Latin America.


Author(s):  
Jeffrey Lawrence

Anxieties of Experience: The Literatures of the Americas from Whitman to Bolaño offers a new interpretation of US and Latin American literature from the nineteenth century to the present. Revisiting longstanding debates in the hemisphere about whether the source of authority for New World literature derives from an author’s first-hand contact with American places and peoples or from a creative (mis)reading of existing traditions, the book charts a widening gap in how modern US and Latin American writers defined their literary authority. In the process, it traces the development of two distinct literary strains in the Americas: the “US literature of experience” and the “Latin American literature of the reader.” Reinterpreting a range of canonical works from Walt Whitman’s Leaves of Grass to Roberto Bolaño’s 2666, Anxieties of Experience shows how this hemispheric literary divide fueled a series of anxieties, misunderstandings, and “misencounters” between US and Latin American authors. In the wake of recent calls to rethink the “common grounds” approach to literature across the Americas, the book advocates a comparative approach that highlights the distinct logics of production and legitimation in the US and Latin American literary fields. Anxieties of Experience closes by exploring the convergence of the literature of experience and the literature of the reader in the first decades of the twenty-first century, arguing that the post-Bolaño moment has produced the strongest signs of a truly reciprocal literature of the Americas in more than a hundred years.


Author(s):  
Detlef Pollack ◽  
Gergely Rosta

The growth of Evangelical Protestantism and Pentecostalism is widely regarded as a potent argument against the validity of secularization theory. To explain this growth, Chapter 12 draws on theoretical approaches to analysing new social movements, which allows an expansion of the repertoire of explanations concerning religious change and a testing of alternatives to the models provided by secularization theory. To explain the worldwide growth and relative resilience of the Evangelical and Pentecostal movements, the chapter identifies a number of conditions and explanatory factors: cultural and social confirmation, religious syncretism, social deprivation, and the widespread magical worldview and broadly accepted spiritistic beliefs in Latin American countries that are conducive to the acceptance of Pentecostal experiences and healing rituals.


Heliyon ◽  
2021 ◽  
pp. e06393
Author(s):  
Irina Oltean ◽  
Jason Tran ◽  
Sarah Lawrence ◽  
Brittany Ann Ruschkowski ◽  
Na Zeng ◽  
...  

2021 ◽  
Vol 224 (2) ◽  
pp. S357
Author(s):  
Stacey Gold ◽  
Haleema Saeed ◽  
Neggin Mokhtari ◽  
Rebecca L. Chornock ◽  
Melissa Fries ◽  
...  

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