Incidence and risk factor for short term postoperative cough after thyroidectomy

Abstract Background The prevalence of potential risk factors for postoperative cough after thyroidectomy remain unknown. The current study aimed to research postoperative cough in patients undergoing thyroid surgery prospectively. Methods Adult patients who underwent primary thyroid surgery were selected prospectively. Data regarding age, sex, BMI, pathology and surgical procedure were collected and analyzed. The Leicester Cugh Questionnaire (LCQ) was required to be completed by all patients before operation, 2 weeks and 4 weeks after operation. Results There were 1264 patients enrolled in total. Eleven patients with vocal cord paralysis were excluded. In patients with benign disease, postoperative cough occurred in 61 patients, with an prevalence rate of 17. 0% compared to an prevalence rate of 33.1% in patients with malignant disease; the difference was significant. For benign patients, the factors of smoking and operation time were independently related to the occurrence of postoperative cough. For malignant patients, the factors of smoking, operation time, operation extent, and the number of positive nodes at level 6 were independently related to the occurrence of postoperative cough. There was no significant difference regarding the LCQ score in patients with benign or malignant disease at the preoperative and the postoperative 4-week time periods. Patients with malignant disease had a significantly lower LCQ score than patients with benign disease at the postoperative 2-week time point (p = 0.004). Conclusions Patients undergoing thyroid cancer surgery had a higher incidence of postoperative cough and were also associated with a decreased cough-related quality of life. The factors of smoking and operation time were the most important predictors for postoperative cough after thyroidectomy.

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Incidence and risk factor for short term postoperative cough after thyroidectomy

10.21203/rs.3.rs-27699/v5 ◽

2020 ◽

Author(s):

Junfu Wu ◽

Liyuan Dai ◽

Weihua Lou

Keyword(s):

Thyroid Surgery ◽

Prevalence Rate ◽

Malignant Disease ◽

Operation Time ◽

Benign Disease ◽

Time Operation ◽

Significant Difference ◽

Related Quality ◽

Potential Risk Factors ◽

The Difference

Abstract Background: The prevalence of potential risk factors for postoperative cough after thyroidectomy remain unknown. The current study aimed to research postoperative cough in patients undergoing thyroid surgery prospectively.Methods: Adult patients who underwent primary thyroid surgery were selected prospectively. Data regarding age, sex, BMI, pathology and surgical procedure were collected and analyzed. The Leicester Cugh Questionnaire (LCQ) was required to be completed by all patients before operation, 2 weeks and 4 weeks after operation.Results: There were 1264 patients enrolled in total. Eleven patients with vocal cord paralysis were excluded. In patients with benign disease, postoperative cough occurred in 61 patients, with an prevalence rate of 17. 0% compared to an prevalence rate of 33.1% in patients with malignant disease; the difference was significant. For benign patients, the factors of smoking and operation time were independently related to the occurrence of postoperative cough. For malignant patients, the factors of smoking, operation time, operation extent, and the number of positive nodes at level 6 were independently related to the occurrence of postoperative cough. There was no significant difference regarding the LCQ score in patients with benign or malignant disease at the preoperative and the postoperative 4-week time periods. Patients with malignant disease had a significantly lower LCQ score than patients with benign disease at the postoperative 2-week time point (p=0.004).Conclusions: Patients undergoing thyroid cancer surgery had a higher incidence of postoperative cough and were also associated with a decreased cough-related quality of life. The factors of smoking and operation time were the most important predictors for postoperative cough after thyroidectomy.

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Incidence and risk factor for short term postoperative cough after thyroidectomy

10.21203/rs.3.rs-27699/v4 ◽

2020 ◽

Author(s):

Junfu Wu ◽

Liyuan Dai ◽

Weihua Lou

Keyword(s):

Prevalence Rate ◽

Malignant Disease ◽

Operation Time ◽

Benign Disease ◽

Time Operation ◽

Leicester Cough Questionnaire ◽

Significant Difference ◽

Related Quality ◽

Potential Risk Factors ◽

The Difference

Abstract BackgroundThe prevalence of and potential risk factors for postoperative cough after thyroidectomy remain unknown. The current study aimed to analyze postoperative cough in patients undergoing thyroidectomy using a prospective analysis.MethodsAdult patients undergoing primary thyroidectomy were prospectively enrolled. Data regarding age, sex, BMI, pathology and surgical procedure were collected and analyzed. All patients were asked to complete the Leicester Cough Questionnaire (LCQ) preoperatively and at 2 weeks and 4 weeks postoperatively.ResultsThere were 1264 patients enrolled in total. Eleven patients with vocal cord paralysis were excluded. In patients with benign disease, postoperative cough occurred in 61 patients, with an prevalence rate of 17. 0% compared to an prevalence rate of 33.1% in patients with malignant disease; the difference was significant. For benign patients, the factors of smoking and operation time were independently related to the occurrence of postoperative cough. For malignant patients, the factors of smoking, operation time, operation extent, and the number of positive nodes at level 6 were independently related to the occurrence of postoperative cough. There was no significant difference regarding the LCQ score in patients with benign or malignant disease at the preoperative and the postoperative 4-week time periods. Patients with malignant disease had a significantly lower LCQ score than patients with benign disease at the postoperative 2-week time point (p=0.004).ConclusionsPatients undergoing thyroid cancer surgery had a higher prevalence of postoperative cough and were also associated with a decreased cough-related quality of life. The factors of smoking and operation time were the most important predictors for postoperative cough after thyroidectomy.

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Incidence and risk factor for short term postoperative cough after thyroidectomy

10.21203/rs.3.rs-27699/v2 ◽

2020 ◽

Author(s):

Junfu Wu ◽

Liyuan Dai ◽

Weihua Lou

Keyword(s):

Prevalence Rate ◽

Malignant Disease ◽

Operation Time ◽

Benign Disease ◽

Time Operation ◽

Leicester Cough Questionnaire ◽

Significant Difference ◽

Related Quality ◽

Potential Risk Factors ◽

The Difference

Abstract Background: The prevalence of and potential risk factors for postoperative cough after thyroidectomy remain unknown. The current study aimed to analyze postoperative cough in patients undergoing thyroidectomy using a prospective analysis.Methods: Adult patients undergoing primary thyroidectomy were prospectively enrolled. Data regarding age, sex, BMI, pathology and surgical procedure were collected and analyzed. All patients were asked to complete the Leicester Cough Questionnaire (LCQ) preoperatively and at 2 weeks and 4 weeks postoperatively.Results: There were 1264 patients enrolled in total. Eleven patients with vocal cord paralysis were excluded. In patients with benign disease, postoperative cough occurred in 61 patients, with an prevalence rate of 17. 0% compared to an prevalence rate of 33.1% in patients with malignant disease; the difference was significant. For benign patients, the factors of smoking and operation time were independently related to the occurrence of postoperative cough. For malignant patients, the factors of smoking, operation time, operation extent, and the number of positive nodes at level 6 were independently related to the occurrence of postoperative cough. There was no significant difference regarding the LCQ score in patients with benign or malignant disease at the preoperative and the postoperative 4-week time periods. Patients with malignant disease had a significantly lower LCQ score than patients with benign disease at the postoperative 2-week time point (p=0.004).Conclusions: Patients undergoing thyroid cancer surgery had a higher prevalence of postoperative cough and were also associated with a decreased cough-related quality of life. The factors of smoking and operation time were the most important predictors for postoperative cough after thyroidectomy.

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Incidence and risk factor for short term postoperative cough after thyroidectomy

10.21203/rs.3.rs-27699/v1 ◽

2020 ◽

Author(s):

Junfu Wu ◽

Liyuan Dai ◽

Weihua Lou

Keyword(s):

Prevalence Rate ◽

Malignant Disease ◽

Operation Time ◽

Benign Disease ◽

Time Operation ◽

Leicester Cough Questionnaire ◽

Significant Difference ◽

Related Quality ◽

Potential Risk Factors ◽

The Difference

Abstract Background The prevalence of and potential risk factors for postoperative cough after thyroidectomy remain unknown. The current study aimed to analyze postoperative cough in patients undergoing thyroidectomy using a prospective analysis. Methods Adult patients undergoing primary thyroidectomy were prospectively enrolled. Data regarding age, sex, BMI, pathology and surgical procedure were collected and analyzed. All patients were asked to complete the Leicester Cough Questionnaire (LCQ) preoperatively and at 2 weeks and 4 weeks postoperatively. Results There were 1264 patients enrolled in total. In patients with benign disease, postoperative cough occurred in 62 patients, with an prevalence rate of 17.2% compared to an prevalence rate of 32.9% in patients with malignant disease; the difference was significant. For benign patients, the factors of smoking and operation time were independently related to the occurrence of postoperative cough. For malignant patients, the factors of smoking, operation time, operation extent, and the number of positive nodes at level 6 were independently related to the occurrence of postoperative cough. There was no significant difference regarding the LCQ score in patients with benign or malignant disease at the preoperative and the postoperative 4-week time periods. Patients with malignant disease had a significantly lower LCQ score than patients with benign disease at the postoperative 2-week time point (p = 0.001). Conclusions Patients undergoing thyroid cancer surgery had a higher prevalence of postoperative cough and were also associated with a decreased cough-related quality of life. The factors of smoking and operation time were the most important predictors for postoperative cough after thyroidectomy.

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Incidence and risk factor for short term postoperative cough after thyroidectomy

10.21203/rs.3.rs-27699/v3 ◽

2020 ◽

Author(s):

Junfu Wu ◽

Liyuan Dai ◽

Weihua Lou

Keyword(s):

Prevalence Rate ◽

Malignant Disease ◽

Operation Time ◽

Benign Disease ◽

Time Operation ◽

Leicester Cough Questionnaire ◽

Significant Difference ◽

Related Quality ◽

Potential Risk Factors ◽

The Difference

Abstract Abstract Background : The prevalence of and potential risk factors for postoperative cough after thyroidectomy remain unknown. The current study aimed to analyze postoperative cough in patients undergoing thyroidectomy using a prospective analysis. Methods : Adult patients undergoing primary thyroidectomy were prospectively enrolled. Data regarding age, sex, BMI, pathology and surgical procedure were collected and analyzed. All patients were asked to complete the Leicester Cough Questionnaire (LCQ) preoperatively and at 2 weeks and 4 weeks postoperatively. Results : There were 1264 patients enrolled in total. Eleven patients with vocal cord paralysis were excluded. In patients with benign disease, postoperative cough occurred in 61 patients, with an prevalence rate of 17. 0% compared to an prevalence rate of 33.1% in patients with malignant disease; the difference was significant. For benign patients, the factors of smoking and operation time were independently related to the occurrence of postoperative cough. For malignant patients, the factors of smoking, operation time, operation extent, and the number of positive nodes at level 6 were independently related to the occurrence of postoperative cough. There was no significant difference regarding the LCQ score in patients with benign or malignant disease at the preoperative and the postoperative 4-week time periods. Patients with malignant disease had a significantly lower LCQ score than patients with benign disease at the postoperative 2-week time point (p=0.004). Conclusions : Patients undergoing thyroid cancer surgery had a higher prevalence of postoperative cough and were also associated with a decreased cough-related quality of life. The factors of smoking and operation time were the most important predictors for postoperative cough after thyroidectomy.

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Comparison of Inflammatory Reactions Following Two Different Cesarean Section Techniques: The Modified Misgav-Ladach Versus the Pfannenstiel-Kerr; A Prospective Randomized Trial

Gynecology Obstetrics and Reproductive Medicine ◽

10.21613/gorm.2018.811 ◽

2018 ◽

pp. 1

Author(s):

Baris Buke ◽

Hatice Akkaya ◽

Cigdem Karakukcu

Keyword(s):

Cesarean Section ◽

Inflammatory Reaction ◽

Operation Time ◽

Blood Samples ◽

Inflammatory Reactions ◽

Tnf Α ◽

Significant Difference ◽

The Difference ◽

Group 2 ◽

Group 1

Objectives: There is not yet a consensus on the optimal surgical technique for cesarean section. This is the first study comparing two different (Cesarean Section) with respect to the following inflammatory reaction in means of changes in inflammatory marker levels. To evaluate the differences in inflammatory reactions following two different (Cesarean Section) techniques, the modified Misgav-Ladach versus the Pfannenstiel-Kerr technique.Study Desıgn: The study population included 88 pregnant women who met the inclusion criteria. These women were randomized into two groups according to Consolidated Standards of Reporting Trials guidelines: Group 1 (Misgav-Ladach group) and Group 2 (Pfannenstiel Kerr group). To compare the inflammatory reactions following surgery, Interleukin-6 (IL-6) and Tumor Necrosis Factor-α (TNF-α) levels were measured in venous blood samples drawn from the patients just before (0 hour) and 24 hours (24th hour) after the surgery. In 5 women from Group 1 and 2 women from Group 2, the 24th hour blood samples could not be obtained or were lost. Thus, a total of 81 women, 39 women from Group 1 and 42 women from Group 2, comprised the population of study. The differences in inflammatory reactions between the 0 and 24th hours were analyzed by calculating the percent change in IL-6 and TNF-α levels, and these percentages were then compared between the groups.Results: There was a statistically significant difference between Group 1 and Group 2 regarding the serum IL-6 level change between 0 and 24th hour (530±653% and 196±168%, respectively, p=0.022. The difference in TNF-α was also higher in Group 2, but the difference was not statistically significant (229±306% vs. 571±824%, p=0.12). The mean operation time was significantly shorter in Group 1 (9.44 min. vs. 16.86 min, p=0.0001).Conclusions: The results of this study indicate that the modified Misgav-Ladach technique has a weaker inflammatory reaction, which indicates fewer short- and long-term surgical complications.

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Predictive Value of Charlson Comorbidity Index and Cofactors on 2-Year Mortality in Older Patients With Intertrochanteric Fractures: A Retrospective Analysis

10.21203/rs.3.rs-136253/v1 ◽

2021 ◽

Author(s):

Jianda Xu ◽

Homma Yasuhiro ◽

Yuta Jinnai ◽

Tomonori Baba ◽

Zhuang Xu ◽

...

Keyword(s):

Blood Loss ◽

Older Patients ◽

Demographic Data ◽

Survival Rates ◽

Operation Time ◽

Intertrochanteric Fractures ◽

Time Out ◽

Time Operation ◽

Significant Difference ◽

First Time

Abstract The aim of this study was to evaluate the role of Charlson comorbidities index (CCI) and cofactors on 2-year mortality in older patients with intertrochanteric fractures. 60 cases with unilateral intertrochanteric fracture were retrospectively analyzed and divided into Low-CCI group (CCI: 1-4) or high-CCI groups (CCI: 5-6). All the patients’ electronic hospital records were reviewed. The preoperative situations (demographic data, comorbidities and fracture conditions), perioperative situations (wait time, operation time, implant choice, blood loss, transfusion or not) and postoperative situations (complications, first time out of bed, function about 1-/2- week and 2-year mortality) were recorded. 51.67% were in low-CCI group and 48.33% in high-CCI group. The survival rates in low- and high-CCI group were 93.5% and 86.2 % respectively. According to the functional results of 1- or 2- week after operation, no significant difference was found (P=0.955, 0.140). Log-rank analysis showed that the main prognostic factors were blood loss, first time out of bed and complication (P<0.05). Multivariate analysis confirmed that complication and first time out of bed were significant factor on survival rate (P=0.029, 0.010). Charlson comorbidities index maybe not the indicator of 2-year mortality in older patients with intertrochanteric fractures. In order to improve the prognosis, more attentions should be paid to reduce the complications and encourage postoperative earlier excise out of bed.

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Patterns of metastasis in follicular thyroid carcinoma and the difference between early and delayed presentation

Annals of The Royal College of Surgeons of England ◽

10.1308/rcsann.2016.0300 ◽

2017 ◽

Vol 99 (2) ◽

pp. 151-154 ◽

Cited By ~ 11

Author(s):

R Parameswaran ◽

J Shulin Hu ◽

N Min En ◽

WB Tan ◽

NK Yuan

Keyword(s):

Metastatic Disease ◽

Thyroid Surgery ◽

Survival Data ◽

External Beam Radiotherapy ◽

Good Prognosis ◽

Delayed Presentation ◽

Common Site ◽

Significant Difference ◽

The Difference

Introduction Follicular thyroid cancer (FTC) has a good prognosis if treated early. The aim of this study was to look at the difference in outcomes in those who presented with metastasis early or late in their disease. Methods A retrospective cohort study was conducted of patients diagnosed with FTC (n=91) treated between 2000 and 2013. Demographic, laboratory, pathological and survival data were collected and analysed. Results Metastatic FTC was diagnosed in 20 cases (22%). The median age at diagnosis was 65 years (range: 17–86 years) and 65% of the patients were female. Twelve patients (60%) were diagnosed with metastatic disease at presentation, with the bones being the most common site (75%). In the remaining eight cases (40%), metastasis developed at a median of 4.5 years (range: 2–8 years) after initial thyroid surgery, lungs being the most common site (50%). Eighteen patients (90%) underwent surgical intervention for the primary disease. Sixteen patients (80%) received adjuvant radioactive iodine and eight (40%) received external beam radiotherapy. Widely invasive follicular cancer was the predominant histological diagnosis (90%). No prognostic association was observed with any of the parameters studied. The overall disease specific mortality rate was 40%. There was no significant difference in mortality between those who presented with metastatic disease and those who developed metastasis during the follow-up period (33% vs 50%, p=0.61). Conclusions The clinical outcome and prognosis for cases with metastatic disease is generally poor. Despite this, almost half of the patients in our study were still alive at a median follow-up of 5.5 years, regardless of whether they were diagnosed with metastatic disease on initial presentation or whether they developed metastasis after initial thyroid surgery.

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A Study of Applying RFID for Heat Block Management in IC Packaging Factory

International Journal of Advanced Pervasive and Ubiquitous Computing ◽

10.4018/japuc.2010040104 ◽

2010 ◽

Vol 2 (2) ◽

pp. 57-68 ◽

Cited By ~ 1

Author(s):

Wei-Ling Wang ◽

Shu-Jen Wang ◽

Chiao-Tzu Huang

Keyword(s):

Integrated Circuit ◽

Operation Time ◽

Wire Bond ◽

Ic Packaging ◽

Significant Difference ◽

Before And After ◽

Test Of Hypothesis ◽

The Difference ◽

Die Bonding

In the integrated circuit (IC) packaging process, including operations of die sawing, die bonding, wire bonding, molding, plating, marking, trim/form, and inspection. Purposes of packaging include protecting ICs, making ICs easier to handle, and connecting ICs to the circuit outside. The wire bond stations are the bottleneck in the packaging and assemble process where the heat block is the key auxiliary parts in the stations. This research proposes a RFID-enabled Heat Block Management System (RHMS) to accurately control the progress of the IC packaging production line to meet the customer requirements. Our research analyzed all the flows of heat block management operations during before and after introducing RHMS. Hypothesis testing can verify significant difference between two sample sizes. Based on the statistics test of hypothesis, we compared the difference for before and after introducing RHMS. The results show that the RHMS can bring advantage for heat block management in wire bond stations. Moreover, it has clear improvement of saving counting and revising operation time. The contributions of this research are not only a case study but also a direction for applying RFID technology on IC packaging industry.

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Efficacy of Intraoperative Single Dose Methylprednisolone on Recurrent Laryngeal Nerve Function After Thyroidectomy

International Surgery ◽

10.9738/intsurg-d-15-00222.1 ◽

2016 ◽

Vol 101 (3-4) ◽

pp. 116-120 ◽

Cited By ~ 5

Author(s):

Ali Ugur Emre ◽

Guldeniz Karadeniz Cakmak ◽

Dilek Karakaya Arpaci ◽

Sevil Uygun Ilikhan ◽

Murat Damar

Keyword(s):

Single Dose ◽

Recurrent Laryngeal Nerve ◽

Thyroid Surgery ◽

Recovery Time ◽

Recovery Period ◽

Operation Time ◽

Laryngeal Nerve ◽

Nerve Function ◽

Significant Difference ◽

Group 1

Recurrent laryngeal nerve (RLN) palsy is an important complication of thyroid surgery. Injuries can either be permanent or temporary. Prevention or shortening the recovery period of temporary palsies is an area of interest. Some surgeons prefer to use corticosteroids for this purpose as is used for facial nerve palsies although there are conflicting data in the literature. We aimed to investigate the efficacy of perioperative single dose methylprednisolone on recurrent laryngeal nerve function. A total of 438 nerves under risk in 237 surgeries are investigated in 2 groups. In Group 1, patients are administered a single intraoperative dose of methylprednisolone (1 mg/kg) intravenously for 220 nerves under risk. A total of 218 nerves under risk in Group 2 were operated and followed without methylprednisolone. The demographic data of the patients, operation time, the final pathology reports, incidence of recurrent laryngeal nerve palsy, and recovery time are documented and compared. No statistically significant difference was determined in terms of age, sex distribution, number of nerves under risk, and the operation time between groups. There were 3 unilateral RLNP in each group and the mean recovery time for Group 1 and 2 palsies were 20.4 and 19.8 days, respectively, without statistical significance. The presented data indicates that a single intraoperative dose of steroid does not seem to affect the rate and recovery period of RLNP in thyroid surgery.

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