scholarly journals State-level trends in sudden unexpected infant death and immunization in the United States: an ecological study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jacqueline Müller-Nordhorn ◽  
Konrad Neumann ◽  
Thomas Keil ◽  
Stefan N. Willich ◽  
Sylvia Binting
Keyword(s):  
United States ◽  
Infant Mortality ◽  
Infant Death ◽  
Immunization Coverage ◽  
The United States ◽  
Mortality Rates ◽  
Sleep Position ◽  
Live Births ◽  
Unexpected Infant Death ◽  
Rate Ratios

Abstract Background Sudden unexpected infant death (SUID) continues to be a major contributor to infant mortality in the United States. The objective was to analyze time trends in SUID and their association with immunization coverage. Methods The number of deaths and live births per year and per state (1992–2015) was obtained from the Centers for Disease Control and Prevention (CDC). We calculated infant mortality rates (i.e., deaths below one year of age) per 1000 live births for SUID. We obtained data on immunization in children aged 19–35 months with three doses or more of diphtheria-tetanus-pertussis (3+ DTP), polio (3+ Polio), and Haemophilus influenzae type b (3+ Hib) as well as four doses or more of DTP (4+ DTP) from the National Immunization Survey, and data on infant sleep position from the Pregnancy Risk Assessment Monitoring System (PRAMS) Study. Data on poverty and race were derived from the Current Population and American Community Surveys of the U.S. Census Bureau. We calculated mean SUID mortality rates with 95% confidence interval (CI) as well as the annual percentage change using breakpoint analysis. We used Poisson regression with random effects to examine the dependence of SUID rates on immunization coverage, adjusting for sleep position and poverty (1996–2015). In a second model, we additionally adjusted for race (2000–2015). Results Overall, SUID mortality decreased in the United States. The mean annual percent change was − 9.6 (95% CI = − 10.5, − 8.6) between 1992 and 1996, and − 0.3 (95% CI = − 0.4, − 0.1) from 1996 onwards. The adjusted rate ratios for SUID mortality were 0.91 (95% CI = 0.80, 1.03) per 10% increase for 3+ DTP, 0.88 (95% CI = 0.83, 0.95) for 4+ DTP, 1.00 (95% CI = 0.90, 1.10) for 3+ polio, and 0.95 (95% CI = 0.89, 1.02) for 3+ Hib. After additionally adjusting for race, the rate ratios were 0.76 (95% CI = 0.67, 0.85) for 3+ DTP, 0.83 (95% CI = 0.78, 0.89) for 4+ DTP, 0.81 (95% CI = 0.73, 0.90) for 3+ polio, and 0.94 (95% CI = 0.88, 1.00) for 3+ Hib. Conclusions SUID mortality is decreasing, and inversely related to immunization coverage. However, since 1996, the decline has slowed down.

Regional Contribution of Previable Infant Deaths to Infant Mortality Rates in the United States

2019 ◽  
Author(s):  
MacKenzie Lee ◽  
Eric S. Hall ◽  
Meredith Taylor ◽  
Emily A. DeFranco
Keyword(s):  
United States ◽  
Infant Mortality ◽  
Infant Death ◽  
The United States ◽  
Mortality Rates ◽  
Population Based ◽  
Infant Mortality Rate ◽  
Infant Deaths ◽  
Live Births ◽  
Healthy People 2020

Objective Lack of standardization of infant mortality rate (IMR) calculation between regions in the United States makes comparisons potentially biased. This study aimed to quantify differences in the contribution of early previable live births (<20 weeks) to U.S. regional IMR. Study Design Population-based cohort study of all U.S. live births and infant deaths recorded between 2007 and 2014 using Centers for Disease Control and Prevention's (CDC's) WONDER database linked birth/infant death records (births from 17–47 weeks). Proportion of infant deaths attributable to births <20 vs. 20 to 47 weeks, and difference (ΔIMR) between reported and modified (births ≥20 weeks) IMRs were compared across four U.S. census regions (North, South, Midwest, and West). Results Percentages of infant deaths attributable to birth <20 weeks were 6.3, 6.3, 5.3, and 4.1% of total deaths for Northeast, Midwest, South, and West, respectively, p < 0.001. Contribution of < 20-week deaths to each region's IMR was 0.34, 0.42, 0.37, and 0.2 per 1,000 live births. Modified IMR yielded less regional variation with IMRs of 5.1, 6.2, 6.6, and 4.9 per 1,000 live births. Conclusion Live births at <20 weeks contribute significantly to IMR as all result in infant death. Standardization of gestational age cut-off results in more consistent IMRs among U.S. regions and would result in U.S. IMR rates exceeding the healthy people 2020 goal of 6.0 per 1,000 live births.

scholarly journals Altitude and risk of sudden unexpected infant death in the United States

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Richard Johnston ◽  
Xiaohan Yan ◽  
Tatiana M. Anderson ◽  
Edwin A. Mitchell
Keyword(s):  
United States ◽  
Logistic Regression ◽  
Infant Death ◽  
The United States ◽  
Sudden Infant ◽  
Data Set ◽  
Live Births ◽  
Sudden Unexpected Infant Death ◽  
Increased Risk ◽  
Unexpected Infant Death

AbstractThe effect of altitude on the risk of sudden infant death syndrome (SIDS) has been reported previously, but with conflicting findings. We aimed to examine whether the risk of sudden unexpected infant death (SUID) varies with altitude in the United States. Data from the Centers for Disease Control and Prevention (CDC)’s Cohort Linked Birth/Infant Death Data Set for births between 2005 and 2010 were examined. County of birth was used to estimate altitude. Logistic regression and Generalized Additive Model (GAM) were used, adjusting for year, mother’s race, Hispanic origin, marital status, age, education and smoking, father’s age and race, number of prenatal visits, plurality, live birth order, and infant’s sex, birthweight and gestation. There were 25,305,778 live births over the 6-year study period. The total number of deaths from SUID in this period were 23,673 (rate = 0.94/1000 live births). In the logistic regression model there was a small, but statistically significant, increased risk of SUID associated with birth at > 8000 feet compared with < 6000 feet (aOR = 1.93; 95% CI 1.00–3.71). The GAM showed a similar increased risk over 8000 feet, but this was not statistically significant. Only 9245 (0.037%) of mothers gave birth at > 8000 feet during the study period and 10 deaths (0.042%) were attributed to SUID. The number of SUID deaths at this altitude in the United States is very small (10 deaths in 6 years).

Letter To The Editor

PEDIATRICS ◽  
1970 ◽  
Vol 45 (6) ◽  
pp. 1044-1044
Author(s):  
Alfred Yankauer
Keyword(s):  
United States ◽  
Infant Mortality ◽  
Infant Death ◽  
The United States ◽  
Mortality Rates ◽  
European Countries ◽  
Death Rates ◽  
Letter To The Editor

Second, Dr. Yankauer: "Disgraceful and totally unacceptable" are inflammatory adjectives. They stir up uncomfortable feelings of personal guilt and blame. It would be reassuring if the differences between infant mortality rates in the United States and those of several small European countries with relatively homogenous populations and stable traditions could be explained away as statistical artefacts. Unfortunately the differences cannot be explained away. Clear evidence for their substance is the fact that infant death rates after the first month of life are three times as high in the United States as in Sweden.

Shouldn't SIDS Be Recognized?

PEDIATRICS ◽  
1977 ◽  
Vol 60 (4) ◽  
pp. 548-549
Author(s):  
LOUIS BORGENICHT
Keyword(s):  
United States ◽  
Infant Mortality ◽  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Sudden Infant Death ◽  
The United States ◽  
Mortality Rates ◽  
Vital Statistics ◽  
Sudden Infant

To the Editor: Dr. Wegman's article “Annual Summary of Vital Statistics-1974”(Pediatrics 56:960, December 1975) provides some valuable and interesting information. There is, however, some disconcerting information in Table III,“Infant Mortality Rates by Age and Selective Causes for the United States, 1964 and 1974.” There is no specific listing for the major cause of infant mortality between 1 and 12 months of age: sudden infant death syndrome (SIDS). As Dr. Wegman suggests, “To be

scholarly journals The evolution of infant mortality inequality in the United States, 1960–2016

2020 ◽  
Vol 6 (29) ◽  
pp. eaba5908
Author(s):  
Nick Turner ◽  
Kaveh Danesh ◽  
Kelsey Moran
Keyword(s):  
United States ◽  
Infant Mortality ◽  
The United States ◽  
Mortality Rates ◽  
County Level ◽  
Level Data ◽  
Antipoverty Programs ◽  
The Relationship ◽  
Over Time ◽  
Mortality Inequality

What is the relationship between infant mortality and poverty in the United States and how has it changed over time? We address this question by analyzing county-level data between 1960 and 2016. Our estimates suggest that level differences in mortality rates between the poorest and least poor counties decreased meaningfully between 1960 and 2000. Nearly three-quarters of the decrease occurred between 1960 and 1980, coincident with the introduction of antipoverty programs and improvements in medical care for infants. We estimate that declining inequality accounts for 18% of the national reduction in infant mortality between 1960 and 2000. However, we also find that level differences between the poorest and least poor counties remained constant between 2000 and 2016, suggesting an important role for policies that improve the health of infants in poor areas.

scholarly journals A new record linkage for assessing infant mortality rates in Ontario, Canada

2019 ◽  
Vol 111 (2) ◽  
pp. 278-285 ◽  
Author(s):  
Deshayne B. Fell ◽  
Alison L. Park ◽  
Ann E. Sprague ◽  
Nehal Islam ◽  
Joel G. Ray
Keyword(s):  
Infant Mortality ◽  
Live Birth ◽  
Infant Death ◽  
Mortality Rates ◽  
Vital Statistics ◽  
Infant Mortality Rate ◽  
Income Quintile ◽  
Alternative Source ◽  
Live Births ◽  
Birth Records

Abstract Objective Infant mortality statistics for Canada have routinely omitted Ontario—Canada’s most populous province—as a high proportion of Vital Statistics infant death registrations could not be linked with their corresponding Vital Statistics live birth registrations. We assessed the feasibility of linking an alternative source of live birth information with infant death registrations. Methods All infant deaths occurring before 365 days of age registered in Ontario’s Vital Statistics in 2010–2011 were linked with birth records in the Canadian Institute for Health Information’s hospitalization database. Crude birthweight-specific and gestational age-specific infant mortality rates were calculated, and rates examined according to maternal and infant characteristics. Results Of 1311 infant death registrations, only 47 (3.6%) could not be linked to a hospital birth record. The overall crude infant mortality rate was 4.7 deaths per 1000 live births (95% CI, 4.4 to 4.9), the same as previously reported for the rest of Canada in 2011. Infant mortality was higher in women < 20 years (5.8 per 1000 live births) and ≥ 40 years (5.9 per 1000 live births), and lowest among those aged 25–29 years (3.9 per 1000 live births). Infant mortality was notably higher in the lowest (5.1 per 1000 live births) residential income quintile than the highest (3.4 per 1000 live births). Conclusion Use of birth hospitalization records resulted in near-complete linkage of all Vital Statistics infant death registrations. This approach could enhance the conduct of representative surveillance and research on infant mortality when direct linkage of live birth and infant death registrations is not achievable.

Comparison of Neonatal and Infant Mortality Rates between Infants Born in South Korea and Those Born in the United States

2014 ◽  
Vol 21 (4) ◽  
pp. 211 ◽  
Author(s):  
Ji Sun Lee ◽  
Jung Min Yoon ◽  
Eun Jung Cheon ◽  
Kyong Og Ko ◽  
Jae Won Shim ◽  
...  
Keyword(s):  
United States ◽  
Infant Mortality ◽  
South Korea ◽  
The United States ◽  
Mortality Rates

scholarly journals Trends in the Incidence of New‐Onset Hypertensive Disorders of Pregnancy Among Rural and Urban Areas in the United States, 2007 to 2019

2022 ◽  
Author(s):  
Natalie A. Cameron ◽  
Ian Everitt ◽  
Laura E. Seegmiller ◽  
Lynn M. Yee ◽  
William A. Grobman ◽  
...  
Keyword(s):  
United States ◽  
Urban Areas ◽  
The United States ◽  
Hypertensive Disorders Of Pregnancy ◽  
Live Births ◽  
Rural And Urban Areas ◽  
Hypertensive Disorders ◽  
Rural And Urban ◽  
Rate Ratios ◽  
New Onset

Background Hypertensive disorders of pregnancy are growing public health problems that contribute to maternal morbidity, mortality, and future risk of cardiovascular disease. Given established rural‐urban differences in maternal cardiovascular health, we described contemporary trends in new‐onset hypertensive disorders of pregnancy in the United States. Methods and Results We conducted a serial, cross‐sectional analysis of 51 685 525 live births to individuals aged 15 to 44 years from 2007 to 2019 using the Centers for Disease Control and Prevention Natality Database. We included gestational hypertension and preeclampsia/eclampsia in individuals without chronic hypertension and calculated the age‐adjusted incidence (95% CI) per 1000 live births overall and by urbanization status (rural or urban). We used Joinpoint software to identify inflection points and calculate rate of change. We quantified rate ratios to compare the relative incidence in rural compared with urban areas. Incidence (95% CI) of new‐onset hypertensive disorders of pregnancy increased from 2007 to 2019 in both rural (48.6 [48.0–49.2] to 83.9 [83.1–84.7]) and urban (37.0 [36.8–37.2] to 77.2 [76.8–77.6]) areas. The rate of annual increase in new‐onset hypertensive disorders of pregnancy was more rapid after 2014 with greater acceleration in urban compared with rural areas. Rate ratios (95% CI) comparing incidence of new‐onset hypertensive disorders of pregnancy in rural and urban areas decreased from 1.31 (1.30–1.33) in 2007 to 1.09 (1.08–1.10) in 2019. Conclusions Incidence of new‐onset hypertensive disorders of pregnancy doubled from 2007 to 2019 with persistent rural‐urban differences highlighting the need for targeted interventions to improve the health of pregnant individuals and their offspring.

Sign in / Sign up

Export Citation Format

Share Document