scholarly journals Subjective cognitive complaints and relations to objective cognitive performance among Lebanese patients with schizophrenia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chadia Haddad ◽  
Pascale Salameh ◽  
Hala Sacre ◽  
Clément Polin ◽  
Jean-Pierre Clément ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Performance ◽  
Structural Equation ◽  
Significant Proportion ◽  
Healthy Controls ◽  
Cognitive Complaints ◽  
General Psychopathology ◽  
Cognitive Complaint ◽  
Significant Difference ◽  
Subjective Cognitive Complaints

Abstract Background Patients with schizophrenia have a particularly low level of insight into their illness compared to people with other mental health disorders. The objectives of the study were to evaluate: 1) subjective cognitive complaints in individuals with schizophrenia in comparison with health controls, 2) the relation between subjective cognitive complaint (SCC) and objective cognitive performance in the patients group, and 3) factors related to cognitive complaint, such as depression, insight, autonomy, and psychological symptoms. Methods Cross-sectional study was conducted between July 2019 and March 2020 enrolled 120 patients with schizophrenia disorders, selected from the Psychiatric Hospital of the Cross (HPC) – Lebanon and 60 healthy controls. The Self-Assessment Scale of Cognitive Complaints in Schizophrenia (SASCCS) was used to measure people living with schizophrenia perception of their cognitive impairment, while the Brief Assessment of Cognition in Schizophrenia (BACS) was used to evaluate their cognitive functioning. Results A significant difference was found between schizophrenia patients and healthy controls in all neurocognition and SASCCS tests. The hierarchical regression analysis showed that the BACS total score (Beta = −.06, p = .04), the PANSS general psychopathology (Beta = .29, p = .003), higher depression (Beta = .75, p = .003) were significantly associated with higher SCC. However, higher autonomy (Beta = − 6.35, p = .001) was significantly associated with lower SCC. A Structural equation model showed that the two most contributing variables were general psychopathology (Standardized Beta (SB): .33, p < 0.001) and autonomy (SB: −.29, p < 0.001). Conclusion A significant proportion of patients with schizophrenia could estimate their cognitive impairment. It also showed a positive correlation between depression and activity of daily living with SCC, suggesting that this aspect should be investigated alongside the clinical symptoms when a patient with schizophrenia presents with SCC.

What Do Cognitive Complaints in a Sample of Memory Clinic Outpatients Reflect?

GeroPsych ◽  
2011 ◽  
Vol 24 (4) ◽  
pp. 187-195 ◽  
Author(s):  
Anna Mascherek ◽  
Daniel Zimprich ◽  
Roland Rupprecht ◽  
Frieder R. Lang
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Functioning ◽  
Cognitive Performance ◽  
Semantic Fluency ◽  
Regression Analyses ◽  
Memory Clinic ◽  
Cognitive Complaints ◽  
Cognitive Measures ◽  
Conflicting Evidence ◽  
Subjective Cognitive Complaints

Conflicting evidence exists concerning the value of cognitive complaints in the course of assessing cognitive performance in individuals. The present study examines whether cognitive complaints are differentially related to cognitive functioning in groups with different diagnoses. 169 older outpatients (76 years on average) were divided into three groups and diagnosed with subjective cognitive complaints, mild cognitive impairment, or dementia. They were then administered a self-rating questionnaire on cognitive complaints, with semantic fluency and global cognitive functioning being assessed as cognitive measures. Multiple regression analyses revealed that, after controlling for depression, age, sex, and education, global cognitive functioning was not related to cognitive complaints. Semantic fluency was related to cognitive complaints depending on the group. Results suggest that cognitive complaints reflect, in part, actual cognitive performance.

Indicators for cognitive performance and subjective cognitive complaints in multiple sclerosis: a role for advanced MRI?

2013 ◽  
Vol 20 (8) ◽  
pp. 1131-1134 ◽  
Author(s):  
Hanneke E Hulst ◽  
Karin Gehring ◽  
Bernard MJ Uitdehaag ◽  
Leo H Visser ◽  
Chris H Polman ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Cognitive Performance ◽  
Diffusion Tensor ◽  
Demographic Data ◽  
Gray Matter Volume ◽  
Cognitive Complaints ◽  
Disease Characteristics ◽  
Conventional Mri ◽  
Subjective Cognitive Complaints

Previous studies showed that advanced neuroimaging measures (functional MRI, diffusion tensor imaging) could distinguish multiple sclerosis (MS) patients with and without cognitive impairment. Are these measures indeed better indicators for cognitive impairment or subjective cognitive complaints than conventional MRI? Fifty MS patients and 29 controls were investigated. Regression analysis, including socio-demographic data, disease characteristics, psychological measures, and (advanced) neuroimaging, showed that worse cognitive performance was associated with male sex, lower education, and lower gray matter volume. Subjective cognitive complaints were associated with fatigue and less hippocampal atrophy. Advanced MRI measures did not add to the predictive power of our model.

A-16 MoCA Subtest Analysis: Discriminating between Healthy Controls and MCI

2021 ◽  
Vol 36 (6) ◽  
pp. 1057-1057
Author(s):  
Lauren N Ratcliffe ◽  
Taylor F McDonald ◽  
Craig Marker
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Assessment ◽  
Pacific Islander ◽  
Word Recall ◽  
Healthy Controls ◽  
Cognitive Markers ◽  
Attention Tasks ◽  
Asian Pacific Islander ◽  
Significant Difference ◽  
Asian Pacific

Abstract Objective The Montreal Cognitive Assessment (MoCA) is a suitable, sensitive, and specific cognitive screener for detecting mild cognitive impairment (MCI). Previous research has found markers to discriminate between healthy controls and MCI on MoCA subtest scores. Specifically, MCI performed worse on executive functioning and attention tasks (i.e., inverse digits, serial 7’s, repetition, fluency, abstraction, and word recall). The aim of the present study is to assess for discrimination patterns in MoCA performance between healthy controls and MCI. Method Data was collected through the National Alzheimer’s Coordinating Center (NACC). A sample of healthy controls (n = 3776, 65% female, 80% White, 17% Black, 3% Asian/Pacific Islander) and MCI (n = 1143; 51% female, 82% White, 15% Black, 3% Asian/Pacific Islander) were examined. Results An initial independent t-test revealed a statistically significant difference in MoCA scores for healthy controls (M = 26.18, SD = 2.78) and MCI (M = 22.01, SD = 3.49; t(4917) = 36.91, p = 0.000, Cohen’s d = 1.32). Additional t-tests were performed to compare MoCA subtest scores and domain scores for diagnostic groups. There was a statistically significant difference for healthy controls and MCI groups across all MoCA subtests and domains. Further examination using normal distribution revealed worse performance on cube copy and word recall in MCI groups. Conclusions Consistent with previous findings, word recall was able to discriminate between healthy controls and MCI. However, this study was able to find discrimination in cube copy performance. These findings may guide clinicians to use these interval changes as early cognitive markers for impairment, allowing for early detection and intervention.

scholarly journals Using network analysis to explore cognitive domains in patients with unipolar versus bipolar depression: a prospective naturalistic study

CNS Spectrums ◽  
2019 ◽  
Vol 25 (3) ◽  
pp. 380-391 ◽  
Author(s):  
Cesare Galimberti ◽  
Monica Francesca Bosi ◽  
Valentina Caricasole ◽  
Riccardo Zanello ◽  
Bernardo Dell’Osso ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Network Analysis ◽  
Cognitive Performance ◽  
Bipolar Depression ◽  
Correlation Coefficients ◽  
Unipolar Depression ◽  
Executive Dysfunction ◽  
Network Graph ◽  
Significant Difference ◽  
Neurocognitive Profiles

Objective.Despite growing evidence in the field of cognitive function in mood disorders, the neurocognitive profiles of patients with unipolar and bipolar depression still need further characterization. In this study, we applied network analysis, hypothesizing this approach could highlight differences between major depressive disorder (MDD) and bipolar disorder (BD) from a cognitive perspective.Methods.The cognitive performance of 109 patients (72 unipolar and 37 bipolar depressed outpatients) was assessed through the Montreal Cognitive Assessment (MoCA), and a series of clinical variables were collected. Differences in cognitive performance between MDD and BD patients were tested using non-parametric tests. Moreover, a network graph representing MoCA domains as nodes and Spearman’s rho correlation coefficients between the domains as edges was constructed for each group.Results.The presence of mild cognitive impairment was observed in both MDD and BD patients during depression. No statistical significant difference was found between the two groups in terms of overall cognitive performance and across single domains. Nonetheless, network analytic metrics demonstrated different roles of memory and executive dysfunction in MDD versus BD patients: in particular, MDD network was more densely interconnected than BD network, and memory was the node with the highest betweenness and closeness centrality in MDD, while executive function was more central in BD.Conclusions.From a network analytic perspective, memory impairment displays a central role in the cognitive impairment of patients with unipolar depression, whereas executive dysfunction appears to be more central in bipolar depression. Further research is warranted to confirm our results.

Association of Subjective Cognitive Complaints and Objective Cognitive Impairment in Late Life Depression

2018 ◽  
Vol 26 (3) ◽  
pp. S90-S91
Author(s):  
Ruth Morin ◽  
David D. Bickford ◽  
Yiu Ho Au ◽  
Kelly B. Scherer ◽  
Daniel C. Catalinotto ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Late Life ◽  
Late Life Depression ◽  
Cognitive Complaints ◽  
Subjective Cognitive Complaints

scholarly journals Detecting Subtle Cognitive Impairment in Multiple Sclerosis with the Montreal Cognitive Assessment

2020 ◽  
Vol 47 (5) ◽  
pp. 620-626 ◽  
Author(s):  
Kim Charest ◽  
Alexandra Tremblay ◽  
Roxane Langlois ◽  
Élaine Roger ◽  
Pierre Duquette ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Cognitive Deficits ◽  
Cognitive Assessment ◽  
Cognitive Status ◽  
Montreal Cognitive Assessment ◽  
Rapid Screening ◽  
Cognitive Complaints ◽  
Subjective Complaints ◽  
Subjective Cognitive Complaints

ABSTRACT:Background:Although cognitive deficits are frequent in multiple sclerosis (MS), screening for them with tools such as the Montreal Cognitive Assessment (MoCA) test is usually not performed unless there is a subjective complaint. The Multiple Sclerosis Neuropsychological Questionnaire (MSNQ) is among the instruments most commonly used to assess self-reported subjective complaints in MS. Nonetheless, it does not always accurately reflect cognitive status; many patients with cognitive deficits thus fail to receive appropriate referral for detailed neuropsychological evaluation. The objective of this study was to examine the validity of the MoCA test to detect the presence of objective cognitive deficits among patients with MS without subjective complaints using the Minimal Assessment of Cognitive Function in MS (MACFIMS) as the gold standard.Methods:The sample included 98 patients who were recruited from a university hospital MS clinic. The MSNQ was used to select patients without subjective cognitive complaints who also completed the MACFIMS, MoCA test and MSQOL-54.Results:23.5% of patients without subjective cognitive complaints had evidence of objective cognitive impairment on the MACFIMS (z score < -1.5 on two or more tests). The MoCA had a sensitivity of 87% and a specificity of 68% for detecting objective cognitive impairment in this patient population using a cut-off score of 27.Conclusion:A significant proportion of patients without self-reported cognitive impairment do have evidence of cognitive deficits on more exhaustive cognitive assessment. The MoCA is a rapid screening test that could be used to target patients for whom a more detailed neuropsychological assessment would be recommended.

scholarly journals Predictors of objective cognitive impairment and subjective cognitive complaints in patients with Fabry disease

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Simon Körver ◽  
Gert J. Geurtsen ◽  
Carla E. M. Hollak ◽  
Ivo N. van Schaik ◽  
Maria G. F. Longo ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Fabry Disease ◽  
Cognitive Complaints ◽  
Subjective Cognitive Complaints

scholarly journals Evaluating the Efficacy of a Cognitive Skills Training Program for Spanish-Speaking Adults with Subjective Cognitive Complaints

2019 ◽  
Vol 34 (7) ◽  
pp. 1270-1270
Author(s):  
Y Patino ◽  
P Sinclair ◽  
J Osher ◽  
K Torres
Keyword(s):  
Training Program ◽  
Cognitive Performance ◽  
Cognitive Training ◽  
Cultural Sensitivity ◽  
Cognitive Skills ◽  
Skills Training ◽  
Spanish Version ◽  
Cognitive Complaints ◽  
Spanish Speaking ◽  
Subjective Cognitive Complaints

Abstract Objective The purpose of this pilot study was to examine the efficacy of a five-week Spanish cognitive skills training program on 18 participants with subjective cognitive complaints. Participants and Method Eighteen Spanish-speaking participants completed a series of cognitive and emotional measures pre- and post-training, including objective measures of cognitive functioning (Montreal Cognitive Assessment, Spanish-version; MoCA), self-reported mood measures (Beck Depression Inventory, BDI; Beck Anxiety Inventory, BAI-Spanish version), and subjective cognitive complaints questionnaire (Subjective Cognitive Decline Questionnaire, Spanish version). Drawing from existing literature on effective interventions for subjective cognitive impairment (Reijnders et al., 2015), this research focused on delivering a five-week intervention program in Spanish, which included psychoeducation on cognition, cognitive strategy training, and applied practice of mindfulness techniques. Furthermore, this intervention incorporated Personalismo and indirect communication, which was applied by engaging with participants in a warm and culturally appropriate manner (Jiménez et al., 2014). Results Participants demonstrated significant improvement in overall MoCA scores. Improvements in subjective cognitive performance, as well as decreases in depression and anxiety (as indicated by the BDI and BAI, respectively) were noted. Results also showed that changes in mood, anxiety, and subjective cognitive performance were not predictive of improvements in MoCA performance, lending support to the hypothesis that skills learned in the program contributed to improved cognitive performance. Conclusions Overall, these results demonstrate that linguistically and culturally tailored psychoeducation regarding cognition, cognitive skills training, and mindfulness, can positively impact subjective and objective cognitive performance, as well as psychological wellbeing among Spanish-speaking adults. References Jiménez, A.L., Alegría, M., Camino-Gaztambide, R.F., & Zayas I, L.V. (2014) Cultural sensitivity: What should we understand about Latinos? In R. Parekh (ed.) The Massachusetts General Hospital Textbook on Diversity and Cultural Sensitivity in Mental Health (pp.61-70). New York, NY: Springer. Rebok, G. W., Ball, K., Guey, L. T., Jones, R. N., Kim, H. Y., King, J. W., … ACTIVE Study Group (2014). Ten-year effects of the advanced cognitive training for independent and vital elderly cognitive training trial on cognition and everyday functioning in older adults. Journal of the American Geriatrics Society, 62(1), 16–24. doi:10.1111/jgs.12607.

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