scholarly journals Association of adiponectin and socioeconomic status in African American men and women: the Jackson heart study

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Sharon K. Davis ◽  
Ruihua Xu ◽  
Pia Riestra ◽  
Samson Y. Gebreab ◽  
Rumana J. Khan ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
African American ◽  
African American Men ◽  
Jackson Heart Study ◽  
Men And Women ◽  
Heart Study

Abstract P084: Associations of Anger and Hostility with the Metabolic Syndrome: Cross-sectional Analyses from the Jackson Heart Study

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Janice E Williams ◽  
Sharon B Wyatt ◽  
Mario Sims ◽  
Thomas H Mosley ◽  
Patricia M Dubbert ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
African American ◽  
Disease Risk ◽  
African American Men ◽  
Cardiovascular Disease Risk ◽  
Continuous Variables ◽  
Jackson Heart Study ◽  
Men And Women ◽  
The Metabolic Syndrome ◽  
Heart Study

There is evidence that anger and hostility are positively associated with the metabolic syndrome. In turn, the metabolic syndrome mediates the association between anger and hostility and adverse cardiac events. Very little is known about these associations in African-American populations. We assessed the hypothesis that anger and hostility are positively associated with the metabolic syndrome in an African-American cohort. Participants were 2,732 African-American men and women, ages 45 – 95, who were enrolled in the Jackson Heart Study at baseline. Anger was measured using the Spielberger State-Trait Anger Inventory, and hostility was measured using the Cook-Medley Hostility Scale. The metabolic syndrome was defined by the National Cholesterol Education Program, Adult Treatment Panel III criteria. Overall anger, components anger-in and anger-out, and hostility scores were entered into separate logistic regression models as continuous variables. In models adjusted for age, sex, educational level, and physical activity, higher levels of overall anger (β = 0.024, p = 0.006), anger-in (β = 0.028, p = 0.04), anger-out (β = 0.037, p = 0.04), and hostility (β = 0.021, p = 0.04) were associated with an increased prevalence of the metabolic syndrome. The correlation between anger and hostility was statistically significant but not strong (r = 0.38, p <0.0001). In men, 5 of the 16 individual anger items were significantly associated with the metabolic syndrome. The strongest was “I lose my temper” (β = 0.395, p = 0.003) and “I tend to harbor grudges” (β = 0.314, p = 0.008). In women, only 1 anger item, “I make sarcastic remarks” (β = 0.189, p = 0.04) was associated with the metabolic syndrome. In conclusion, higher levels of overall anger, anger-in, anger-out, and hostility were associated with an increased prevalence of the metabolic syndrome in middle- and older-aged African-American men and women. In men, an angry temperament and a tendency to hold grudges were particularly strong correlates of the metabolic syndrome. Increased understanding of the negative emotions anger and hostility among African-Americans may provide greater insights into cardiovascular disease risk in their population.

scholarly journals Using ECG Machine Learning for Detection of Cardiovascular Disease in African American Men and Women: the Jackson Heart Study

2020 ◽  
Author(s):  
James Pollard ◽  
Kazi T Haq ◽  
Katherine Lutz ◽  
Nichole Rogovoy ◽  
Kevin Paternostro ◽  
...  
Keyword(s):  
Machine Learning ◽  
Cardiovascular Disease ◽  
African American ◽  
African American Men ◽  
Random Effect ◽  
Detection Methods ◽  
Jackson Heart Study ◽  
Men And Women ◽  
Heart Study ◽  
Free Women

Background: Almost half of African American (AA) men and women have cardiovascular disease (CVD). Detection of prevalent CVD in barbershops would facilitate secondary prevention of CVD. We sought to investigate the cross-sectional association of prevalent CVD and sex with global electrical heterogeneity (GEH) and develop a tool for CVD detection. Methods: Participants from the Jackson Heart Study (JHS) with analyzable ECGs (n=3,679; age, 62 ± 12 years; 36% men) were included. QRS, T, and spatial ventricular gradient (SVG) vectors magnitude and direction, and traditional metrics were measured on 12-lead ECG. Linear regression and mixed linear models with random intercept were adjusted for cardiovascular risk factors, sociodemographic and anthropometric characteristics, type of median beat, and mean RR intervals. Random forests, convolutional neural network, and lasso models were developed in 80%, and validated in 20% samples. Results: In fully adjusted models, women had a smaller spatial QRS-T angle (-12.2(-19.4 to-5.1) ° ; P=0.001), SAI QRST (-29.8(-39.3 to -20.3) mV*ms; P<0.0001), and SVG elevation (-4.5(-7.5 to -1.4) ° ; P=0.004) than men, but larger SVG azimuth (+16.2(10.5-21.9) ° ; P<0.0001), with a significant random effect between families (+20.8(8.2-33.5) ° ; P=0.001). SAI QRST was larger in women with CVD as compared to CVD-free women or men (+15.1(3.8-26.4) mV*ms; P=0.009). Men with CVD had smaller T area [by 5.1 (95%CI 1.2-9.0) mV*ms] than CVD-free men, but there were no differences when comparing women with CVD to CVD-free women. Machine-learning detected CVD with ROC AUC 0.69-0.74; plug-in-based model included only age and QRS-T angle. Conclusions: GEH varies by sex. Sex modifies an association of GEH with CVD. Automated CVD detection is feasible.

scholarly journals Association of ADIPOQ gene with type 2 diabetes and related phenotypes in African American men and women: the Jackson Heart Study

BMC Genetics ◽  
2015 ◽  
Vol 16 (1) ◽  
Author(s):  
Sharon K. Davis ◽  
Ruihua Xu ◽  
Samson Y. Gebreab ◽  
Pia Riestra ◽  
Amadou Gaye ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
African American ◽  
African American Men ◽  
Jackson Heart Study ◽  
Men And Women ◽  
Adipoq Gene ◽  
Heart Study

scholarly journals Objective and Subjective Measures of Socioeconomic Status Are Associated with Metabolic Syndrome Severity Among African American Adults in the Jackson Heart Study (P18-006-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Michelle Cardel ◽  
Yi Guo ◽  
Mario Sims ◽  
Akilah Dulin ◽  
Darci Miller ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Socioeconomic Status ◽  
African American ◽  
Waist Circumference ◽  
Social Status ◽  
National Institutes Of Health ◽  
Jackson Heart Study ◽  
Heart Study

Abstract Objectives In this study, data from the Jackson Heart Study (JHS) were used to assess the independent associations between objective socioeconomic status (OSS) and subjective social status (SSS) with metabolic syndrome (MetS) severity and MetS indicators in African American (AA) adults at baseline and eight years later. Methods Participants included 3870 AA participants (63.1% women; mean age 53.8 ± 13.0, age range 35–84 years). OSS was assessed using annual household income and years of school completed. SSS was measured with the MacArthur Scale, using two 10-rung “ladders” with U.S. society and the individual's community as referent groups for their perceived social rank. Associations of OSS and SSS with a sex- and race/ethnic-specific MetS severity Z-score were examined after adjustment for demographics and MetS risk factors (i.e., nutrition, physical activity, smoking status, and alcohol consumption) at baseline and 8-year follow-up. Results Independent of OSS, demographic, and lifestyle factors, individuals who placed themselves on lower rungs of a visual ladder depicting relative social standing in society had more severe metabolic syndrome at baseline but not 8-years later (P = 0.0123 and P = 0.3248, respectively). The components of MetS driving the relationship between US-level SSS and MetS severity at baseline were waist circumference and triglyceride levels, as waist circumference and triglycerides at baseline were inversely associated with US-level SSS (P = 0.0124 and P = 0.0074, respectively). OSS components, including measures of income and education, were both independently associated with MetS severity at baseline (P < 0.05) but not at 8-year follow-up. Community-level SSS was not associated with MetS severity at baseline or 8-year follow-up. Conclusions These data indicate that both subjective and objective measures of social status are independently associated with cardiometabolic risk factors and the severity of MetS among AA adults and should be considered in adjunct when exploring the role of social determinants of cardiometabolic health. Funding Sources This work was supported by the National Institutes of Health National Heart, Lung, and Blood Institute (R01HL120960 R25HL126146 and K01HL141535) and the National Center For Advancing Translational Sciences of the National Institutes of Health (UL1TR001427).

scholarly journals Carotenoid intakes, assessed by food-frequency questionnaires (FFQs), are associated with serum carotenoid concentrations in the Jackson Heart Study: validation of the Jackson Heart Study Delta NIRI Adult FFQs

2008 ◽  
Vol 11 (10) ◽  
pp. 989-997 ◽  
Author(s):  
Sameera A Talegawkar ◽  
Elizabeth J Johnson ◽  
Teresa C Carithers ◽  
Herman A Taylor ◽  
Margaret L Bogle ◽  
...  
Keyword(s):  
African American ◽  
African American Men ◽  
Assessment Tools ◽  
Food Sources ◽  
Jackson Heart Study ◽  
Cross Sectional ◽  
Food Frequency ◽  
Southern Us ◽  
Heart Study ◽  
Β Carotene

AbstractObjectivesIntake and status of carotenoids have been associated with chronic disease. The objectives of this study were to examine the association between carotenoid intakes as measured by two regional food-frequency questionnaires (FFQs) and their corresponding measures in serum, and to report on dietary food sources of carotenoids in Jackson Heart Study (JHS) participants.DesignCross-sectional analysis of data for 402 African American men and women participating in the Diet and Physical Activity Sub-Study (DPASS) of the JHS.ResultsMean serum carotenoid concentrations and intakes in this population were comparable to those reported for the general US population. After adjustment for covariates, correlations between serum and dietary measures of each carotenoid, for the average of the recalls (deattenuated), the short FFQ and the long FFQ, respectively, were: 0·37, 0·35 and 0·21 for α-carotene; 0·35, 0·26 and 0·28 for total (diet plus supplements) β-carotene; 0·25, 0·17 and 0·20 for dietary β-carotene; 0·42, 0·34 and 0·26 for β-cryptoxanthin; 0·33, 0·15 and 0·17 for lutein plus zeaxanthin; and 0·37, 0·19 and 0·14 for lycopene. Major dietary sources of α-carotene were orange vegetables; of β-carotene and lutein plus zeaxanthin, mustard, turnip and collard greens; of β-cryptoxanthin, orange juice; and of lycopene, tomato juice.ConclusionsOn average, carotenoid intakes and serum concentrations are not lower in this southern African American population than the general US population. The two regional FFQs developed for a southern US population and used as dietary assessment tools in the JHS appear to provide reasonably valid information for most of these carotenoids.

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