scholarly journals Exploring lay public and dental professional knowledge around HPV transmission via oral sex and oral cancer development

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Mario A. Brondani ◽  
Adriana B. Siqueira ◽  
Claudia Maria Coelho Alves
Keyword(s):  
Human Papillomavirus ◽  
Oral Cancer ◽  
Health Care Professionals ◽  
Oropharyngeal Cancer ◽  
Hpv Infection ◽  
Cancer Development ◽  
Oral Sex ◽  
Sexual Activities ◽  
Lay Public ◽  
Dental Professionals

Abstract Background Human papillomavirus (HPV) has been associated with certain types of oropharyngeal cancers and yet, the level of knowledge that dental professionals and the lay public have in terms of HPV transmission, oral sexual activities, and oral cancer development needs exploration. The aim of this study was to assess the knowledge held by practicing dental professionals as well as the lay public regarding Human Papillomavirus (HPV) transmission through oral sex and subsequent oropharyngeal cancer development. Methods Textual data were collected from a public forum with dental professionals in. Vancouver, who discussed the HPV-oral sex-oral cancer triad, and from survey data gathered from 212 lay public participants (also in Vancouver) who answered a 13-item questionnaire on the perceived risks of oral sex in terms of HPV infection and oropharyngeal cancer development. The data were analyzed statistically by age group, gender, and sexual orientation using descriptive statistics, while an ANOVA test was used to compare variation in the responses to the survey (p-value = 0.05). Results The forum engaged 46 health care professionals, many of whom were aware of the potential risks for head and neck cancer development due to HPV infection, while also questioning “how to effectively talk about HPV with patients.” The survey revealed that 34.5% of the participants believed that oral sex is an activity with no or low risk for the transmission of HPV, while 84% of participants believed the same sexual practices were of low or no-risk for HIV (Human Immunodeficiency Virus) transmission. Most participants (82%) never discussed oral sexual activities with their physicians or dentists/dental hygienists. Conclusions The general public remains mostly unaware of the potential links between HPV infection and oropharyngeal cancer. Physicians and dental providers should discuss oral sexual practice with their patients to raise awareness.

scholarly journals Oral sex and oral cancer in the context of human papillomavirus infection: lay public understanding

2011 ◽  
Vol 4 (3) ◽  
pp. 171
Author(s):  
Mario A. Brondani ◽  
Mario A. Cruz-Cabrera ◽  
Cheryle Colombe
Keyword(s):  
Human Papillomavirus ◽  
Sexual Orientation ◽  
Oral Cancer ◽  
Small Sample Size ◽  
Hpv Infection ◽  
Small Sample ◽  
Public Understanding ◽  
Sexual Practices ◽  
Cancer Development ◽  
Oral Sex

Human papillomavirus (HPV) is a risk factor for ano-genital and cervical cancers and has been associated with head and neck malignancies in the context of oral sex for the transmission of the virus. However, the level of knowledge that lay people have in terms of HPV transmission through oral sex and oral cancer development remains unknown. A pilot sample of 150 questionnaires was distributed at specific non-profit health organizations in Vancouver, Canada. Questions included perceived risks for oral sex in terms of HPV infection and oral cancer development, and the frequency with which respondents were asked about oral sexual practices by physicians and dentists. Data were analysed statistically by age group (19– 30, 31–50, 50\), gender (male, female), and sexual orientation (queer, straight). 110 questionnaires were returned fully completed. For the transmission of HPV, 58% of the participants believed that oral sex is an activity of no or low risk, whereas 72% considered the same activity to be of no risk for the development of oral cancer. There was no statistical difference between gender and sexual orientation. Participants never discussed related health risks in regard to oral sex with their physicians or dentists. In conclusion, although recent attention has been given to the potential links between HPV infection and oral cancer, such links remain mostly unknown by the public. Physicians and dentists could discuss oral sex practices to raise awareness with their patients. This is a small sample size study and the results should be interpreted with caution.

scholarly journals Association of Salivary Human Papillomavirus Infection and Oral and Oropharyngeal Cancer: A Meta-Analysis

2020 ◽  
Vol 9 (5) ◽  
pp. 1305 ◽  
Author(s):  
Óscar Rapado-González ◽  
Cristina Martínez-Reglero ◽  
Ángel Salgado-Barreira ◽  
Almudena Rodríguez-Fernández ◽  
Santiago Aguín-Losada ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Oral Cancer ◽  
Oropharyngeal Cancer ◽  
Meta Analysis ◽  
Hpv Infection ◽  
Cochrane Library ◽  
Oropharyngeal Carcinoma ◽  
Hpv Dna ◽  
Start Date ◽  
Oral And Oropharyngeal Cancer

Background. Human papillomavirus (HPV) infection has been recognized as an important risk factor in cancer. The purpose of this systematic review and meta-analysis was to determine the prevalence and effect size of association between salivary HPV DNA and the risk of developing oral and oropharyngeal cancer. Methods. A systematic literature search of PubMed, EMBASE, Web of Science, LILACS, Scopus and the Cochrane Library was performed, without language restrictions or specified start date. Pooled data were analyzed by calculating odds ratios (ORs) and 95% confidence intervals (CIs). Quality assessment was performed using the Newcastle–Ottawa Scale (NOS). Results. A total of 1672 studies were screened and 14 met inclusion criteria for the meta-analysis. The overall prevalence of salivary HPV DNA for oral and oropharyngeal carcinoma was 43.2%, and the prevalence of salivary HPV16 genotype was 27.5%. Pooled results showed a significant association between salivary HPV and oral and oropharyngeal cancer (OR = 4.94; 2.82−8.67), oral cancer (OR = 2.58; 1.67−3.99) and oropharyngeal cancer (OR = 17.71; 6.42−48.84). Significant associations were also found between salivary HPV16 and oral and oropharyngeal cancer (OR = 10.07; 3.65−27.82), oral cancer (OR = 2.95; 1.23−7.08) and oropharyngeal cancer (OR = 38.50; 22.43−66.07). Conclusions. Our meta-analysis demonstrated the association between salivary HPV infection and the incidence of oral and oropharyngeal cancer indicating its value as a predictive indicator.

scholarly journals Awareness of oral and genital human papillomavirus (HPV) infection in young adolescents prior to gender-neutral vaccination

2020 ◽  
pp. bmjsrh-2019-200410
Author(s):  
Gillian Knight ◽  
Ben Roberts
Keyword(s):  
Human Papillomavirus ◽  
Oropharyngeal Cancer ◽  
Healthcare Professionals ◽  
Hpv Vaccination ◽  
Intervention Strategy ◽  
Hpv Infection ◽  
Similar Proportion ◽  
Transmitted Infection ◽  
Oral Hpv ◽  
The Impact

IntroductionOral human papillomavirus (HPV) and oropharyngeal cancer prevalence are increasing, particularly in men. Raising greater awareness of male HPV disease is perceived as an important intervention strategy. This study investigated the effectiveness of HPV education on adolescents’ perception of HPV disease and the impact of HPV vaccination on their sexual health.MethodsAn HPV questionnaire was completed by 357 UK-based adolescents, aged 12–13 years.ResultsMost adolescents knew HPV causes cervical cancer and HPV vaccination prevents this. A minority acknowledged HPV causes other genital cancers, with under one-fifth knowing HPV causes genital warts. Adolescents’ awareness of HPV transmission activities were limited. There was very poor awareness of oral HPV infection or HPV-induced oropharyngeal cancer. Half of the participants stated HPV vaccination reduced their concerns about sexually transmitted infection contraction. Over half the males said they may take more sexual risks following vaccination, while a similar proportion of females did not expect their partner to take more risks.ConclusionsAdolescents had little awareness of male HPV infection and the role HPV vaccination can play in preventing these diseases. With variable rates of HPV vaccination uptake in males reported worldwide, this study indicates that in the UK greater emphasis on male HPV disease within educational information is required, to raise better awareness of how HPV affects both genders. As both genders preferred to receive education via healthcare professionals, educating a wider range of healthcare professionals on oral HPV could help facilitate awareness of HPV’s role in head and neck cancer.

scholarly journals Detection of Human Papillomavirus Infection in Oral Cancers reported at Dental Facility: Assessing the Utility of FFPE tissues

2021 ◽  
Author(s):  
Gaurav Verma ◽  
Nikita Aggarwal ◽  
Abhishek Tyagi ◽  
Kanchan Vishnoi ◽  
Mohit Jadli ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Oral Cancer ◽  
Epidemiological Data ◽  
Hpv Infection ◽  
Oral Cancers ◽  
Dental Hospital ◽  
Formalin Fixed Paraffin Embedded ◽  
Ffpe Tissues ◽  
Oral Malignancies ◽  
Protocol Standardization

Abstract Incidence of human papillomavirus (HPV)–associated oral cancers is on the rise. However, epidemiological data of this subset of cancers is limited. Dental hospital pose a unique advantage in detection of HPV-positive oral malignancies. We assessed the utility of formalin-fixed, paraffin-embedded (FFPE) tissues, which are readily available, for evaluation of high-risk HPV infection in oral cancer. For protocol standardization, we used 20 prospectively-collected, paired FFPE and fresh tissues of histopathologically-confirmed oral cancer cases reported in Oral Medicine department of a dental hospital for comparative study. Only short-PCRs (~200bp) of DNA isolated using a modified xylene-free method displayed a concordant HPV result. For HPV analysis, we used additional 30 retrospectively-collected FFPE tissues. DNA isolated from these specimens showed an overall 23.4% (11/47) HPV positivity with detection of HPV18. Comparison of HPV positivity from dental hospital FFPE-specimens with overall HPV positivity of freshly-collected oral cancer specimens (n-55) from three cancer care hospitals of the same region showed notable difference (12.7%; 7/55). Further, cancer hospital specimens showed HPV16 positivity and displayed a characteristic difference in reported sub-sites and patient spectrum. Overall, using a xylene-free FFPE-DNA isolation method clubbed with short amplicon PCR, we showed detection of HPV-positive oral cancer in dental hospitals.

scholarly journals Association between Human papillomavirus and oral cancer in Iranian clinical samples: a meta- analysis review

2021 ◽  
Author(s):  
Tahoora Mousavi ◽  
Mahmood Mosazadeh ◽  
Saeid Taghiloo ◽  
Reza Valadan ◽  
Sogol Sattari ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Oral Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Meta Analysis ◽  
Hpv Infection ◽  
Clinical Samples ◽  
Oral Diseases ◽  
Iranian Patients

Abstract Background: Oral squamous cell carcinoma (OSCC) is one of the most common malignancies and is a serious problem worldwide. The role of HPV in oral cavity squamous cell carcinoma has beenstudied in several researches. Objective: The aim of the present review and meta-analysis was to investigate the relation between human papillomavirus (HPV) and oral cancer. Study design: Relevant studies were found using online international databases and suitable studies were selected and assessed by two independent researchers. The quality of all papers were determined by a checklist. Heterogeneity assay among the primary studies was evaluated by Cochran's Q test and I2 index. The statistical analyses were done using Stata SE, V.11 software. Trim and Fill method was applied to confirm the validity of the results.Results: This meta- analysis consists of 8 primary studies on the incidence of HPV infection in Iranian patients with oral diseases. The odds ratio between HPV infection and risk of oral cancer was 4.00 (95%CI: 2.31, 6.93).Conclusion: This meta- analysis showed associations between prevalence of HPV infection and oral cancer among Iranian patients. The chance of developing oral cancer among HPV positive patients was higher than that in HPV negative patients.

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