scholarly journals Mediation effect of body mass index on the association between spicy food intake and hyperuricemia in rural Chinese adults: the Henan rural cohort study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Xiaokang Dong ◽  
Yuqian Li ◽  
Kaili Yang ◽  
Lulu Zhang ◽  
Yuan Xue ◽  
...  

Abstract Background The relationship of spicy food intake with hyperuricemia remains unknown. The objective of this study was to examine the association between spicy food intake and hyperuricemia, and whether this association was mediated by body mass index (BMI) in Chinese rural population. Methods 38, 027 adults aged 18–79 years were recruited from the Henan Rural Cohort Study. Information on spicy food intake was obtained using a validated questionnaire survey. Multivariable logistic regression model was used to estimate the association between spicy food intake and hyperuricemia, multiple linear regression model was performed to estimate the relationships between spicy food intake, BMI and serum urate level. BMI was used as a mediator to evaluate the mediation effect. Results After adjusting for potential confounders, compared with no spicy food flavor, the odds ratio (OR) and 95% confidence interval (CI) of mild, middle, and heavy flavor for hyperuricemia were 1.09 (1.00–1.19), 1.10 (0.97–1.24), and 1.21 (1.10–1.46), respectively (Ptrend = 0.017). Similarly, compared with those without intake in spicy food, the multivariable adjusted OR (95% CI) of 1-2 days/week, 3–5 days/week, and 6–7 days/week were 1.15 (1.01–1.31), 1.14 (1.01–1.30) and 1.15 (1.05–1.26), respectively (Ptrend = 0.007). However, when we further controlling for BMI, the associations were substantially attenuated. Furthermore, mediation analysis showed that BMI play a full mediating role in the relationship of spicy food intake with hyperuricemia. Conclusion Spicy food flavor and intake frequency are positively related with hyperuricemia in Chinese rural population. BMI may play a full mediating role in the relationship. Trial registration The Henan Rural Cohort Study registered at Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). Date of registration: 2015-07-06.

2020 ◽  
Author(s):  
Xiaokang Dong ◽  
Yuqian Li ◽  
Kaili Yang ◽  
Lulu Zhang ◽  
Yuan Xue ◽  
...  

Abstract Background: The relationship of spicy food intake with hyperuricemia remains unknown. The objective of this study was to examine the association between spicy food intake and hyperuricemia, and whether this association was mediated by body mass index (BMI) in Chinese rural population.Methods: 38, 027 adults aged 18–79 years were recruited from the Henan Rural Cohort Study. Information on spicy food intake was obtained using a validated questionnaire survey. Multivariable logistic regression model was used to estimate the association between spicy food intake and hyperuricemia, multiple linear regression model was performed to estimate the relationships between spicy food intake, BMI and serum urate level. BMI was used as a mediator to evaluate the mediation effect.Results: After adjusting for potential confounders, compared with no spicy food flavor, the odds ratio (OR) and 95% confidence interval (CI) of mild, middle, and heavy flavor for hyperuricemia were 1.09 (1.00-1.19), 1.10 (0.97-1.24), and 1.21 (1.10-1.46), respectively (Ptrend=0.017). Similarly, compared with those without intake in spicy food, the multivariable adjusted OR (95% CI) of 1-2days/week, 3-5 days/week, and 6-7 days/week were 1.15 (1.01-1.31), 1.14 (1.01-1.30) and 1.15 (1.05-1.26), respectively (Ptrend=0.007). However, when we further controlling for BMI, the associations were substantially attenuated. Furthermore, mediation analysis showed that BMI play a full mediating role in the relationship of spicy food intake with hyperuricemia.Conclusion: Spicy food flavor and intake frequency are positively related with hyperuricemia in Chinese rural population. BMI may play a full mediating role in the relationship.


2020 ◽  
Author(s):  
Xiaokang Dong ◽  
Yuqian Li ◽  
Kaili Yang ◽  
Lulu Zhang ◽  
Yuan Xue ◽  
...  

Abstract Background: The relationship of spicy food intake with hyperuricemia remains unknow. The purpose of this study was to examine the association between spicy food intake and hyperuricemia, and whether this association was mediated by body mass index (BMI) in Chinese rural population.Methods: A total of 38, 027 adults, aged 18–79 years, were from the Henan Rural Cohort Study. Information on spicy food intake was obtained using a validated questionnaire survey. Multivariable logistic regression model was used to estimate the association between spicy food intake and hyperuricemia, multiple linear regression model was performed to estimate the relationships between spicy food intake, BMI and serum urate level. BMI was used as a mediator to estimate the mediation effect. Results: After adjusting for potential confounders, compared with no spicy food flavor, the odds ratio (OR) and 95% confidence interval (CI) of mild, middle, and heavy flavor for hyperuricemia was 1.09 (1.00-1.19), 1.10 (0.97-1.24), and 1.21 (1.10-1.46), respectively (Ptrend=0.017). Similarly, compared with no spicy food intake, the adjusted OR (95% CI) of 1 or 2days/week, 3-5 days/week, and 6 or 7 days/week were 1.15 (1.01-1.31), 1.14 (1.01-1.30) and 1.15 (1.05-1.26), respectively (Ptrend=0.007). Associations were substantially attenuated after additional control for BMI. Furthermore, mediation analysis showed that BMI play a full mediating role in the relationship between spicy food intake and hyperuricemia.Conclusion: Spicy food flavor and intake frequency is positively related with hyperuricemia in Chinese rural population. BMI may play a full mediating role in the relationship.


2015 ◽  
Vol 13 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Elena V. Bolotova ◽  
Irina V. Samorodskaya ◽  
Irina M. Komissarova

The aim was to study the relationship of body mass index (BMI) and abdominal obesity with the frequency of comorbid pathology in rural population of Krasnodarsky kray.Materials and methods. The study included 700 rural workers (18 years of age and older) who underwent a preventive medical examination (57,2% of women and 42,8% of men, mean age 49,11±16,57 years).Results. In rural population of Krasnodarsky kray the proportion of the individuals with BMI 25.0–29.9 kg/m2 was 34.7% (statistically more significant in men than in women, р0.0001), the proportion of the individuals with BMI ≥ 30.0 kg/m2 was 39.7% (statistically more significant in women than in men, р0.0001). Abdominal obesity was found in 70.1% of individuals (77.3% of women and 60.5% of men, p=0.0001). In the group of patients with increased BMI, abdominal obesity was more common in women than in men (p=0.0001). In the group of patients with BMI ≥ 30.0 kg/m2 abdominal obesity was revealed in 100% of cases. Risk factors for chronic non-infectious diseases such as hypercholesterolemia (26.7%), hyperglycemia (16.4%), and arterial hypertension (26.1%) were statistically more frequent in the individuals with BMI ≥ 30.0 kg/m2 than in those with normal and increased BMI. The diseases that can be enhanced by the presence of abdominal obesity were registered more often in patients with BMI ≥ 30.0 kg/m2 (97.8%) in comparison with patients with elevated BMI (23.5%; р0,0001) and with normal BMI (4%; р0,0001).Conclusions. Elevated BMI, abdominal obesity and high frequency of comorbid pathology is prevalent in Krasnodarsky kray.


2020 ◽  
Vol 2020 (66) ◽  
pp. 101-110
Author(s):  
. Azhar Kadhim Jbarah ◽  
Prof Dr. Ahmed Shaker Mohammed

The research is concerned with estimating the effect of the cultivated area of barley crop on the production of that crop by estimating the regression model representing the relationship of these two variables. The results of the tests indicated that the time series of the response variable values is stationary and the series of values of the explanatory variable were nonstationary and that they were integrated of order one ( I(1) ), these tests also indicate that the random error terms are auto correlated and can be modeled according to the mixed autoregressive-moving average models ARMA(p,q), for these results we cannot use the classical estimation method to estimate our regression model, therefore, a fully modified M method was adopted, which is a robust estimation methods, The estimated results indicate a positive significant relation between the production of barley crop and cultivated area.


2021 ◽  
pp. 097226292199259
Author(s):  
Devika Rani Sharma ◽  
Balgopal Singh

Emergence of technology has not only boosted the growth of customer engagement but has also paved way for customers to become active co-creators with the firms. Customer engagement activities are taking over the customer relationship building activities in the present scenario. Customers’ experience with a particular brand has its impact on satisfaction levels and their repurchasing intention in future as well. According to Rosetta Consulting report an engaged customer is likely to buy 90% more frequently and may spend 300% more than other customers. Hence, the present has tried to understand the mediating role of satisfaction on customer engagement in retaining the customers or persuading the customers to repurchase. The results show that there exists a significant mediation effect of customer satisfaction in influencing their repeat purchase behaviour.


2006 ◽  
Vol 19 (5) ◽  
pp. 388-395 ◽  
Author(s):  
MAMDOUH M. SHUBAIR ◽  
POORNIMA PRABHAKARAN ◽  
VIKTORIA PAVLOVA ◽  
JAMES L. VELIANOU ◽  
ARYA M. SHARMA ◽  
...  

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Muhammad Asim Rafique ◽  
Yumei Hou ◽  
Muhammad Adnan Zahid Chudhery ◽  
Nida Gull ◽  
Syed Jameel Ahmed

PurposeInnovations are imperative for organizational growth and sustainability. This study focuses on the employees' innovative behavior, a source of organizational innovations, which has received substantial attention from the researchers. Based on the psychological empowerment theory, the study exposes the effect of the various dimensions of public service motivation (PSM) on employees' innovative behavior (IB) in public sector institutions especially in the context of developing countries such as Pakistan. Moreover, the study also investigates the mediating role of psychological empowerment (PSE) between the dimensions of PSM and IB.Design/methodology/approachThis study used the cross-sectional research design. By using random sampling, the adapted survey questionnaires were used to collect data from 346 faculty members of public sector universities located in provincial capitals of Pakistan. A partial least square–structural equation modeling (PLS-SEM) tool was used to assess the proposed hypotheses through SMART-PLS software.FindingsResults revealed that attraction to policymaking (APM), compassion (COM), self-sacrifice (SS) have a significant impact on employees' PSE and their innovative behavior, while the relationship of commitment to the public interest (CPI) with PSE and IB was found insignificant. Moreover, PSE partially mediated the relationship between PSM dimensions and employees' IB.Originality/valueThere was a scarcity of research on IB especially in public sector institutions such as academia. This study theoretically contributed to the literature by providing a refined picture in assessing the proposed relationship of the constructs. This is also one of the original studies that examine the relationship between the dimensions of PSM and IB.


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