Risk factors and the natural history of accelerated knee osteoarthritis: a narrative review

Abstract Hemorrhagic stroke (HS) is a major cause of death and disability worldwide, despite being less common, it presents more aggressively and leads to more severe sequelae than ischemic stroke. There are two types of HS: Intracerebral Hemorrhage (ICH) and Subarachnoid Hemorrhage (SAH), differing not only in the site of bleeding, but also in the mechanisms responsible for acute and subacute symptoms. This is a systematic review of databases in search of works of the last five years relating to the comprehension of both kinds of HS. Sixty two articles composed the direct findings of the recent literature and were further characterized to construct the pathophysiology in the order of events. The road to the understanding of the spontaneous HS pathophysiology is far from complete. Our findings show specific and individual results relating to the natural history of the disease of ICH and SAH, presenting common and different risk factors, distinct and similar clinical manifestations at onset or later days to weeks, and possible complications for both.

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The natural history of radiographic knee osteoarthritis: A fourteen-year population-based cohort study

Arthritis & Rheumatism ◽

10.1002/art.34415 ◽

2012 ◽

Vol 64 (7) ◽

pp. 2243-2251 ◽

Cited By ~ 73

Author(s):

K. M. Leyland ◽

D. J. Hart ◽

M. K. Javaid ◽

A. Judge ◽

A. Kiran ◽

...

Keyword(s):

Cohort Study ◽

Natural History ◽

Knee Osteoarthritis ◽

Population Based ◽

History Of ◽

Radiographic Knee Osteoarthritis

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The Shoulder Instability: An Overview

International Journal of Recent Surgical and Medical Sciences ◽

10.1055/s-0041-1731113 ◽

2021 ◽

Author(s):

Balaji Zacharia ◽

Arun Prakas ◽

Subramanian Vaidyanathan ◽

Antony Roy ◽

Mohammed Komalam Ayyub

Keyword(s):

Natural History ◽

Shoulder Instability ◽

Shoulder Joint ◽

Shoulder Dislocation ◽

Narrative Review ◽

Pathological Anatomy ◽

Dynamic Factors ◽

History Of ◽

Classification And Treatment

AbstractInstability of the shoulder joint is common but most of the time it is unrecognized by the treating surgeon. The symptoms can vary from subtle pain to shoulder dislocation. In many cases, there is no history of trauma. The shoulder joint is stabilized by both static and dynamic factors, and treatment is complex, with recurrence more common in young athletic individuals. Open and arthroscopic techniques of stabilization are available with specific indications for each of these methods. In this narrative review of shoulder instability, we describe the pathological anatomy, evaluation, natural history, classification, and treatment of shoulder instability.

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Mortality in Children and Adolescents With Sickle Cell Disease

PEDIATRICS ◽

10.1542/peds.84.3.500 ◽

1989 ◽

Vol 84 (3) ◽

pp. 500-508 ◽

Cited By ~ 1

Author(s):

Sanford L. Leikin ◽

Dianne Gallagher ◽

Thomas R. Kinney ◽

Desirée Sloane ◽

Panpit Klug ◽

...

Keyword(s):

Risk Factors ◽

Sickle Cell Disease ◽

Natural History ◽

Parental Education ◽

Young Patients ◽

Cell Disease ◽

Cerebrovascular Accidents ◽

Limited Success ◽

History Of ◽

Overall Mortality

A study of the natural history of sickle hemoglobinopathies was begun in March 1979. By August 1987, a total of 2824 patients <20 years of age were enrolled. There have been 14 670 person-years of followup. Seventy-three deaths have occurred. Most of the deaths were in patients with hemoglobin SS. The peak incidence of death was between 1 and 3 years of age, and the major cause in these young patients was infection. Cerebrovascular accidents and traumatic events exceeded infections as a cause of death in patients > 10 years of age. There was limited success in identifying risk factors for death. Comparison of this study's overall mortality of 2.6% (0.5 deaths per 100 person-years) with previous reports indicates improvement of survival in US patients <20 years of age with sickle hemoglobinopathies. This improvement is most likely due to parental education and counseling about the illness and the early institution of antibotics in suspected infections.

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The Natural History of NAFLD: Environmental vs. Genetic Risk Factors

Non-Alcoholic Fatty Liver Disease ◽

10.1007/978-3-319-95828-6_7 ◽

2020 ◽

pp. 129-145

Author(s):

Luca Valenti ◽

Serena Pelusi

Keyword(s):

Risk Factors ◽

Natural History ◽

Genetic Risk ◽

Genetic Risk Factors ◽

History Of

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Risk Factors in Children — The Early Natural History of Atherosclerosis

Atherosclerosis IV ◽

10.1007/978-3-642-95308-8_94 ◽

1977 ◽

pp. 489-497 ◽

Cited By ~ 1

Author(s):

Gerald S. Berenson

Keyword(s):

Risk Factors ◽

Natural History ◽

History Of

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Different Contributions of Dyslipidemia and Obesity to the Natural History of Type 2 Diabetes: 3-Year Cohort Study in China

Journal of Diabetes Research ◽

10.1155/2019/4328975 ◽

2019 ◽

Vol 2019 ◽

pp. 1-10 ◽

Cited By ~ 1

Author(s):

Lu Liu ◽

Xiaoling Guan ◽

Zhongshang Yuan ◽

Meng Zhao ◽

Qiu Li ◽

...

Keyword(s):

Risk Factors ◽

Type 2 Diabetes ◽

Cohort Study ◽

Natural History ◽

Glucose Tolerance ◽

Serum Triglyceride ◽

Glycemic Status ◽

History Of

Aim. It is known that different stages of type 2 diabetes represent distinct pathophysiological changes, but how the spectrum of risk factors varies at different stages is not yet clarified. Hence, the aim of this study was to compare the effect of different metabolic variables on the natural history of type 2 diabetes. Methods. A total of 5,213 nondiabetic (normal glucose tolerance (NGT) and prediabetes) Chinese older than 40 years participated this prospective cohort study, and 4,577 completed the 3-year follow-up. Glycemic status was determined by standard oral glucose tolerance test both at enrollment and follow-up visit. Predictors for conversion in glycemic status were studied in a corresponding subcohort using the multiple logistic regression analysis. Results. The incidence of prediabetes and diabetes of the cohort was 93.6 and 42.2 per 1,000 person-years, respectively. After a 3-year follow-up, 33.1% of prediabetes patients regressed to NGT. The predictive weight of body mass index (BMI), serum triglyceride, total cholesterol, and systolic blood pressure in different paths of conversions among diabetes, prediabetes, and NGT differed. Specifically, BMI was the strongest predictor for regression from prediabetes to NGT, while triglyceride was most prominent for onset of diabetes. One SD increase in serum triglyceride was associated with a 1.29- (95% CI 1.10–1.52; P=0.002) or 1.12- (95% CI 1.01–1.27; P=0.039) fold higher risk of diabetes for individuals with NGT or prediabetes, respectively. Conclusion. Risk factors for different stages of diabetes differed, suggesting personalized preventive strategies for individuals with different basal glycemic statuses.

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