scholarly journals Comparison of novel visceral obesity indexes with traditional obesity measurements in predicting of metabolically unhealthy nonobese phenotype in hemodialysis patients

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chaomin Zhou ◽  
Yanzhe Peng ◽  
Wenyong Jiang ◽  
Jing Yuan ◽  
Yan Zha
Keyword(s):  
Abdominal Obesity ◽  
Visceral Obesity ◽  
Hemodialysis Patients ◽  
Overweight And Obesity ◽  
Visceral Adiposity ◽  
Guizhou Province ◽  
Maintenance Hemodialysis ◽  
Visceral Adiposity Index ◽  
Adiposity Index ◽  
Obesity Indices

Abstract Background Normal-weight maintenance hemodialysis (MHD) patients with abdominal obesity exhibited a more proatherogenic profile than overweight and obesity patients with abdominal obesity, highlighting the importance of early identification of metabolically unhealthy nonobese (MUNO) in this population. Visceral fat accumulation plays a crucial role in the development of MUNO. Lipid accumulation product (LAP), visceral adiposity index (VAI) have been proved as reliable visceral obesity markers. The Chinese visceral adiposity index (CVAI) and a body shape index (ABSI) are newly discovered indexes of visceral obesity and have been reported to be associated with multiple metabolic disorders. There are limited studies investigating the associations between different visceral obesity indices and risk of MUNO, especially in hemodialysis patients. Moreover, no general agreement has been reached to date regarding which of these obesity indices performs best in identifying MUNO. We aimed to investigate the prevalence of MUNO in MHD patients and compare the associations between different adiposity indices (CVAI, ABSI,VAI, LAP, body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHtR)) with MUNO risk in this population. Methods We conducted a multi-center cross-sectional study in Guizhou Province, Southwest China. 1302 nonobese adult MHD patients were included in our study. MUNO was defined as being nonobese and having the presence of > = 2 components of metabolic syndrome (MetS). Nonobese was defined as BMI less than 25 kg/m2. VAI, LAP, CVAI, ABSI, BMI, WC and WHtR were calculated. Logistic regression analyses and receiver operator curve (ROC) analyses were performed. Results 65.6% participants were metabolically unhealthy. The ROC curve analysis demonstrated that of the seven obesity indices tested, the VAI (AUC 0.84 for women and 0.79 for men) followed by LAP (AUC 0.78 for women and 0.72 for men) had the highest diagnostic accuracy for MUNO phenotype while ABSI exhibited the lowest AUC value for identifying MUNO phenotype Conclusions Metabolically unhealthy is highly prevalent in nonobese MHD patients. VAI and LAP outperformed CVAI in discriminating MUNO in MHD patients. Though ABSI could be a weak predictor of MUNO, it is not better than WHtR, WC and BMI.

Chinese visceral adiposity index, a novel indicator of visceral obesity for assessing the risk of incident hypertension in a prospective cohort study

2020 ◽  
pp. 1-9
Author(s):  
Minghui Han ◽  
Ranran Qie ◽  
Quanman Li ◽  
Leilei Liu ◽  
Shengbing Huang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Characteristic Curve ◽  
Visceral Obesity ◽  
Visceral Adiposity ◽  
Sensitivity Analyses ◽  
Cluster Sampling ◽  
Visceral Adiposity Index ◽  
Adiposity Index ◽  
Hypertension Risk ◽  
Obesity Indices

Abstract The present study aimed to investigate the association of the Chinese visceral adiposity index (CVAI) and its 6-year change with hypertension risk and compare the ability of CVAI and other obesity indices to predict hypertension based on the Rural Chinese Cohort Study. Study participants were randomly recruited by a cluster sampling procedure, and 10 304 participants ≥18 years were included. Modified Poisson regression was used to derive adjusted relative risks (RR) and 95 % CI. We identified 2072 hypertension cases during a median of 6·03 years of follow-up. The RR for the highest v. lowest CVAI quartile were 1·29 (95 % CI 1·05, 1·59) for men and 1·53 (95 % CI 1·22, 1·91) for women. Per-sd increase in CVAI was associated with hypertension for both men (RR 1·09, 95 % CI 1·02, 1·16) and women (RR 1·14, 95 % CI 1·06, 1·22). Also, the area under the receiver operating characteristic curve value for hypertension was higher for CVAI than the four other obesity indices for both sexes (all P < 0·05). Finally, per-sd increase in CVAI change was associated with hypertension for both men (RR 1·26, 95 % CI 1·16, 1·36) and women (RR 1·23, 95 % CI 1·15, 1·30). Similar results were observed in sensitivity analyses. CVAI and its 6-year change are positively associated with hypertension risk. CVAI has better performance in predicting hypertension than other visceral obesity indices for both sexes. The current findings suggest CVAI as a reliable and applicable predictor of hypertension in rural Chinese adults.

Visceral Adiposity Index Is Associated with Pre-Diabetes and Type 2 Diabetes Mellitus in Chinese Adults Aged 20-50

2016 ◽  
Vol 68 (4) ◽  
pp. 235-243 ◽  
Author(s):  
Peng Ju Liu ◽  
Fang Ma ◽  
Hui Ping Lou ◽  
Yu Chen
Keyword(s):  
Diabetes Mellitus ◽  
Area Under The Curve ◽  
Visceral Obesity ◽  
Community Dwelling ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Chinese Adults ◽  
Cross Sectional ◽  
Adiposity Index ◽  
Obesity Indices

Background/Aims: Diabetes mellitus and pre-diabetes are closely associated with visceral obesity. Visceral adiposity index (VAI) is a novel sex-specific index, indirectly expressing visceral adipose function. Our aim was to determine the associations of VAI with dysglycemia (the combination of diabetes and pre-diabetes) and to compare the predictive ability for dysglycemia between VAI and traditional obesity indices. Methods: We performed a cross-sectional analysis of the data of 2,754 Chinese community-dwelling people who participated in the health checkup. Sex-specific VAI tertile cut-off points were used as follows: 1.70, 2.77 in males and 0.98, 1.75 in females. Binary logistic regression models were performed to estimate the association of the higher values of all the obesity indices with pre-diabetes and diabetes. The area under the curve (AUC) of the receiver operating characteristic (ROC) curve was applied to compare the predictive potential for dysglycemia among the obesity indices. Results: VAI was the only index significantly associated with both pre-diabetes and diabetes in both sexes after adjusting for potential confounders. The results of ROC analysis and AUC showed that VAI possessed the largest AUC, followed by other obesity indices. Conclusions: Higher VAI values are positively associated with the presence of pre-diabetes and diabetes in Chinese adults.

464-P: Visceral Adiposity Index Identifies Both Type 2 Diabetes Mellitus and Prediabetes Better than Established Indices of Visceral Obesity in a Pad Cohort

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 464-P
Author(s):  
BERNHARD ZIERFUSS ◽  
CLEMENS HOEBAUS ◽  
CARSTEN T. HERZ ◽  
RENATE KOPPENSTEINER ◽  
GERIT-HOLGER SCHERNTHANER
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Visceral Obesity ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Adiposity Index ◽  
Better Than

scholarly journals Visceral adiposity index is closely associated with albuminuria in the Chinese population with prediabetes: results from the REACTION study

2020 ◽  
Author(s):  
Jie Wang ◽  
Binruo Zhu ◽  
Xinye Jin ◽  
Kang Chen ◽  
Wenhua Yan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Logistic Regression ◽  
Chinese Population ◽  
Multiple Logistic Regression Analysis ◽  
Visceral Obesity ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Multiple Logistic Regression ◽  
Adiposity Index ◽  
Increased Risk

Abstract Background Visceral obesity is a major health issue and a risk factor for atherogenic state. It has been reported to be a crucial link between albuminuria and cardiovascular diseases (CVD). However, there is limited available data on the relationship between visceral obesity and albuminuria. Therefore, we aimed to explore the association between visceral obesity and albuminuria in the Chinses population with prediabetes. Methods This cross-sectional study included 24871 prediabetic participants aged over 40 years from seven centers across China. Visceral adiposity index (VAI), which has been confirmed as a simple and reliable indicator of visceral adiposity distribution and dysfunction, is determined based on the measurements of anthropometric indices and lipid parameters. Increased albuminuria was defined as urinary albumin-creatinine ratio (UACR)≥30 mg/g, indicating kidney damage. Propensity score matching was used to reduce the bias and multiple logistic regression model was performed to evaluate the association between visceral obesity and albuminuria in the population with prediabetes. Results Participants with increased UACR had increased VAI, age, blood pressure, triglycerides, poor glycemic control, and decreased estimated glomerular filtration rate (eGFR). The prevalence of CVD was higher in the increased UACR group. Multiple logistic regression analysis showed that VAI quartiles was positively associated with increased risk of albuminuria (Q2: odds rate (OR):1.10, 95% confidence intervals [CI]: 0.96-1.25; Q3: OR:1.16, 95%CI 1.01-1.32; Q4: OR:1.26, 95%CI 1.10-1.44, P for trend=0.001). Stratified analysis revealed that the association of VAI level with increased albuminuria risk was also observed in people who were young, women, overweight or obese, with poor control of blood pressure, and eGFR≥ 90 mL/min per 1.73 m 2 . Conclusions Visceral obesity assessed by VAI was significantly associated with increased albuminuria in the Chinese population with prediabetes.

scholarly journals The Utility of Visceral Adiposity Index in Prediction of Metabolic Syndrome and Hypercholesterolemia

2018 ◽  
Vol 69 (11) ◽  
pp. 3112-3114 ◽  
Author(s):  
Bogdan Socea ◽  
Lucretiu Radu ◽  
Diana Clenciu ◽  
Tiberiu Stefanita Tenea Cojan ◽  
Vlad Baleanu ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Adiposity Index ◽  
Type 2 Dm ◽  
Adolescents And Adults ◽  
Visceral Adipose

Metabolic syndrome (MS) is defined as a complex entity that involves the accumulation of cardiovascular and metabolic risk factors represented by: abdominal obesity, insulin resistance, hypertension, dyslipidemia [1]. The presence of MS correlates with the risk of cardiovascular disease in people without diabetes mellitus (DM), as well as those with type 2 DM [2-8].Visceral adipose tissue is an active metabolic organ and abdominal obesity is an independent risk factor for metabolic disorder present in MS [9,10,11], associated with the development of cardiovascular disease and type 2 diabetes in children, adolescents and adults [12-15]. Our findings have shown an association of visceral adiposity index (VAI) with MS in both men and women with prediabetes and diabetes, these findings allow us to conclude that VAI is a simple but effective indicator for estimating the presence of MS among adults.

scholarly journals Evaluation of Visceral Adiposity Index and Vitamin D Status in Colon Cancer: Is Visceral Obesity the Missing Link?

2021 ◽  
Vol 11 (5) ◽  
pp. 115-122
Author(s):  
Mohamed M. Aboelnaga ◽  
Engy M. Aboelnaga ◽  
Seham E.A. Abdelkhalek ◽  
Mostafa El Shaer ◽  
Nahed Abdallah
Keyword(s):  
Colon Cancer ◽  
Vitamin D ◽  
Visceral Obesity ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Vitamin D Status ◽  
Missing Link ◽  
Adiposity Index

scholarly journals Visceral adiposity index and risks of cardiovascular events and mortality in prevalent hemodialysis patients

2014 ◽  
Vol 13 (1) ◽  
Author(s):  
Hung-Yuan Chen ◽  
Yen-Ling Chiu ◽  
Yi-Fang Chuang ◽  
Shih-Ping Hsu ◽  
Mei-Fen Pai ◽  
...  
Keyword(s):  
Cardiovascular Events ◽  
Hemodialysis Patients ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Adiposity Index
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