Oral health and caries/gingivitis-associated factors of adolescents aged 12–15 in Shandong province, China: a cross-sectional Oral Health Survey

Abstract Background We aimed to analyse the oral health status of adolescents in Shandong province, including dental caries and gingivitis, and their associated factors. Methods Adolescents aged 12–15-years in Shandong province were recruited. Caries and gingival status were assessed following the World Health Organisation diagnostic criteria. Information including the sociodemographic, oral hygiene knowledge, attitudes and practices were collected through the questionnaire. Chi-square test and multivariate logistic regression analysis were used to investigate the oral diseases associated factors. Results In total, 3868 students (50.2% males) were enrolled. Of these, 39.9% of the participants experienced caries, and 81.7% and 31.3% had calculus and bleeding gingival, respectively. Multivariate logistic regression analysis revealed that there was an association between dental caries and toothaches, dental visits and sleeping troubles caused by oral problems (P < 0.024). A low-frequency of brushing, high sugar consumption and no flossing were more associated with calculus formation and gingival bleeding (P < 0.008). Conclusion Compared to caries, worse gingival condition was more prevalent among adolescents in Shandong province. Brushing behaviour is associated with gingivitis, while dental visits and toothaches are associated with caries. Hence, prevention-oriented dental visits and oral hygiene training are strongly recommended to improve oral health status.

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Oral Health and Risk Indicators of Early Adolescents in Shandong Province, China: A Cross-sectional Oral Health Survey

10.21203/rs.3.rs-145470/v1 ◽

2021 ◽

Author(s):

Meng Zhang ◽

Jing Lan ◽

Tiantian Zhang ◽

Wenshuang Sun ◽

Panpan Liu ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Health Status ◽

Oral Health ◽

Multivariate Logistic Regression Analysis ◽

Oral Health Status ◽

Shandong Province ◽

Risk Indicators ◽

Multivariate Logistic Regression ◽

Dental Visits

Abstract Objective: We aimed to analyse the oral health status of adolescents in Shandong province, including dental caries and gingivitis, and the relevant risk indicators.Methods: Adolescents aged 12-15-years in Shandong province were recruited. Caries and gingival status were assessed following the World Health Organisation diagnostic criteria. Information including the sociodemographic, oral hygiene knowledge, attitudes and practices were collected through the questionnaire. Chi-square test and multivariate logistic regression analysis were used to investigate the independent risk indicators.Results: In total, 3,868 students (50.2% males) were enrolled. Of these, 39.9% of the participants experienced caries, and 81.7% and 31.3% had calculus and bleeding gums, respectively. Multivariate logistic regression analysis revealed that there was an association between an increased risk of caries with toothaches, dental visits and sleeping troubles caused by oral problems (P < 0.024). A low-frequency of brushing, high sugar consumption and no flossing increased the risk of calculus formation and gum bleeding (P < 0.008).Conclusion: Compared to caries, worse gingival condition was more prevalent among adolescents in Shandong province and was not taken seriously. Brushing behaviour is associated with gingivitis, while dental visits and toothaches are associated with caries. Hence, prevention-oriented dental visits and oral hygiene training are strongly recommended to improve oral health status.Trial registration: Not applicable.

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The prevalence and associated factors of reduced bone mineral density (BMD) among men with suppressed viral load taking antiretroviral therapy

Current HIV Research ◽

10.2174/1570162x19666211202100308 ◽

2021 ◽

Vol 19 ◽

Author(s):

Safiye Nur Ozcan ◽

Dilek Yıldız Sevgi ◽

Ahsen Oncul ◽

Alper Gunduz ◽

Ozgun Pehlivan ◽

...

Keyword(s):

Bone Mineral Density ◽

Logistic Regression ◽

Regression Analysis ◽

Viral Load ◽

Bone Mineral ◽

Associated Factors ◽

Multivariate Logistic Regression Analysis ◽

Multivariate Logistic Regression ◽

Mineral Density ◽

Hiv Diagnosis

Background: Reduced bone mineral density (BMD) is a frequent comorbidity observed in people living with HIV (PLHIV). Objective: The aim of the study is to determine the prevalence and associated factors of reduced bone mineral density (BMD) among men with suppressed viral load taking antiretroviral therapy. Method: The study was conducted as a cross-sectional study design between January to April 2019. 211 patients were included in the study. Z-score at either body site between -1.0 and -2.0 or -2 or less were defined as osteopenia or osteoporosis, respectively. Multivariate logistic regression analysis was used to evaluate the factors affecting the development of reduced BMD. Results: The mean age of the patients involved in the study was 34.8 ± 7.6. Osteoporosis was detected in 21.4% and osteopenia in 44.5% of the patients. There was a significant relationship between HIV diagnosis time, ART usage duration, tenofovir disoproxil fumarate (TDF) use, TDF use in the past, total TDF usage time and decreased BMD. Multivariate logistic regression analysis showed that the likelihood of reduced bone marrow density was 67% lower among those with regular milk or dairy product intake compared to those without (OR=0.330; 95% CI = 0.12-0.92, p=0.033 ) Conclusion: There is a high prevalence of reduced BMD among PLHIV aged under 50 which is mainly confounded by HIV diagnosis time, ART usage duration and TDF usage. Although virological control has been achieved, these patients should be followed up, considering that they may have decreased BMD.

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Early Initiation of Anticoagulation Improves the Long-Term Prognosis in Patients With Antiphospholipid Syndrome Associated Portal Vein Thrombosis

Frontiers in Medicine ◽

10.3389/fmed.2021.630660 ◽

2021 ◽

Vol 8 ◽

Author(s):

Hanxiao You ◽

Jiuliang Zhao ◽

Can Huang ◽

Xinping Tian ◽

Mengtao Li ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Survival Analysis ◽

Portal Vein ◽

Portal Vein Thrombosis ◽

Antiphospholipid Syndrome ◽

Associated Factors ◽

Multivariate Logistic Regression Analysis ◽

Multivariate Logistic Regression ◽

Vein Thrombosis

Objectives: Portal vein thrombosis (PVT) is a rare and severe clinical phenotype of antiphospholipid syndrome (APS) with a poor prognosis. Anticoagulation therapy is efficient but is associated with potentially severe bleeding episodes, especially for those patients with thrombocytopenia. We conducted this case-control study to explore the clinical features and associated factors of PVT in APS patients, the re-canalization rate of the PVT after anticoagulation and investigate the beneficial effects of early initiation of anticoagulation in patients with APS associated PVT.Methods: We enrolled patients with APS associated PVT as the case group, and age-, and entry-time-matched APS patients without PVT (1:2) as the control group. We explored the associated factors of PVT in APS patients using multivariate logistic regression analysis. The re-canalization rate of the PVT after anticoagulation was analyzed using the survival analysis.Results: A total of 34 patients (8 males and 26 females) with APS-PVT were enrolled, with a median follow-up time of 3 years (1.5, 7 years). Multivariate logistic regression analysis showed that thrombocytopenia (OR 6.4, 95%CI 1.561–26.218, P = 0.01), hypersensitive c-reactive protein >3 mg/L (OR 4.57, 95%CI 1.426–14.666, P = 0.011), anti β2GPI positive (OR 5, 95%CI 1.816–13.772, P = 0.002) and aPL double-positive (OR 4.08, 95%CI 1.312–12.429, P = 0.013) were independent associated factors for PVT in APS. Survival analysis revealed that effective anticoagulation could increase re-canalization rate significantly (log-rank p = 0.001), with better prognosis (lower mortality rate, log-rank p = 0.045).Conclusions: PVT could be the first presentation of APS with insidious onset and atypical clinical symptoms and easily be misdiagnosed. For patients with APS, double aPLs positive, thrombocytopenia, and inflammation could be the associated factors of PVT. Early diagnosis and anticoagulation treatment can bring thrombus re-canalization thereby significantly improving the prognosis.

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Comprehensive Hospitals Nurses’ Cognition on Palliative Care in Shandong Province, China: A Cross-Sectional Study

Iranian Journal of Public Health ◽

10.18502/ijph.v50i7.6623 ◽

2021 ◽

Author(s):

Hailing Yang ◽

Meimei Shang ◽

Chunhua Sun ◽

Lihua Li ◽

Chao Wang

Keyword(s):

Palliative Care ◽

Logistic Regression ◽

Regression Analysis ◽

Multivariate Logistic Regression Analysis ◽

Cross Sectional Study ◽

Shandong Province ◽

Sectional Study ◽

Multivariate Logistic Regression ◽

Cross Sectional ◽

Nursing Knowledge

Background: Palliative care is an essential part of medical practice, however, it has developed slowly in China. We aimed to analyze the current situations of the cognition on palliative care among the nurses in Shandong Province, China. Methods: This was a cross sectional study. Investigation of 1050 nurses came from 5 third-class hospitals and 5 second-class hospitals in Shandong Province, China from Jul to Oct in 2018. The questionnaire included 4 parts: general information of the subject, the questionnaire of palliative nursing knowledge, attitude, and the behavior. Data were collected by the APP. Overall, after eliminating the invalid questionnaires, 1026 questionnaires were included in the final analyses. The software Stata 14.2 was used for all statistical analyses. Results: The score of knowledge and attitude was low, the practice was higher. Multivariate analysis results: the significant independent variables of univariate analysis were included in the multivariate non-conditional logistic regression model for analysis. Some departments had statistical significance in knowledge multivariate Logistic regression analysis. The multivariate logistic regression analysis of practice was significant for physical health and religious beliefs. The statistical variables of the total score of cognition were gender, age of care, health status and religious beliefs. Conclusion: Nursing knowledge is lacking and attitude remains to be improved as soon as possible. It is vital to improve the cognition of palliative care of nurses in Shandong general hospitals by developing relevant rules and regulations, strengthening the supervision of relevant ant departments, and enhancing training for nurses.

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Adherence to Adjuvant Imatinib Therapy in Patients with Gastrointestinal Stromal Tumor in Clinical Practice: A Cross-Sectional Study

Chemotherapy ◽

10.1159/000505177 ◽

2019 ◽

Vol 64 (4) ◽

pp. 197-204

Author(s):

Yirong Wang ◽

Peng Zhang ◽

Yong Han ◽

Ryan S. Nelson ◽

Howard L. McLeod ◽

...

Keyword(s):

Quality Of Life ◽

Social Support ◽

Logistic Regression ◽

Regression Analysis ◽

Health Status ◽

Global Health ◽

Plasma Concentrations ◽

Multivariate Logistic Regression Analysis ◽

Multivariate Logistic Regression

Background: Adherence to imatinib therapy has been significantly associated with disease progression and direct medical costs in gastrointestinal stromal tumor (GIST) patients. However, adherence to oral anticancer drugs is frequently hindered by the influence of various factors. The aim of this study was to evaluate the prevalence of imatinib adherence and its influencing factors among GIST patients in the adjuvant setting. Methods: Adherence of GIST patients (receiving imatinib for ≥1 month) was assessed using the 8-item Morisky Medication Adherence Scale (MMAS), with a score <8 indicating nonadherence. Quality of life and social support were evaluated by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQ C30) and Social Support Rating Scale (SSRS). Factors associated with nonadherence were identified by multivariate logistic regression analysis. Imatinib plasma concentrations were determined and compared between adherent and nonadherent groups. Results: A total of 158 GIST patients were enrolled, 92 (58.2%) patients were considered nonadherent. Intentional nonadherence, especially feeling hassled by treatment plan (34.2% of patients), was common. In the multivariate logistic regression analysis, gender (OR 2.68, 95% CI 1.33–5.41; p = 0.0058), place of residence (OR 3.20, 95% CI 1.39–7.35; p = 0.0061), and global health status (OR 1.02, 95% CI 1.00–1.04; p = 0.0378) were significantly associated with nonadherence. Moreover, imatinib plasma concentrations in nonadherent patients were significantly lower than that in the good adherence group (p = 0.0338). Conclusions: Poor adherence to imatinib is a notable problem in Chinese GIST patients in the adjuvant therapy setting. The predominant indicators of nonadherence in this study were gender (female), living in a rural area, and harboring a low global health status score. These indicators may aid clinicians in determining where increased efforts in promoting adherence may be beneficial.

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Pre hospital delay and its associated factors in acute myocardial infarction in a developing country

PLoS ONE ◽

10.1371/journal.pone.0259979 ◽

2021 ◽

Vol 16 (11) ◽

pp. e0259979

Author(s):

Ishmum Zia Chowdhury ◽

Md. Nurul Amin ◽

Mashhud Zia Chowdhury ◽

Sharar Muhib Rahman ◽

Mohsin Ahmed ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Logistic Regression ◽

Regression Analysis ◽

Chest Pain ◽

Logistic Regression Analysis ◽

Symptom Onset ◽

Associated Factors ◽

Multivariate Logistic Regression Analysis ◽

Multivariate Logistic Regression

Background Early revascularization and treatment is key to improving clinical outcomes and reducing mortality in acute myocardial infarction (AMI). In low- and middle-income countries such as Bangladesh, timely management of AMI is challenging, with pre-hospital delays playing a significant role. This study was designed to investigate pre-hospital delay and its associated factors among patients presenting with AMI in the capital city of Dhaka. Methods This retrospective cohort study was conducted on 333 patients presenting with AMI over a 3-month period at two of the largest primary reperfusion-capable tertiary cardiac care centres in Dhaka. Of the total patients, 239(71.8%) were admitted in the National Institute of Cardiovascular Diseases, Dhaka and 94(28.2%) at Ibrahim Cardiac Hospital & Research Institute, Dhaka Data were collected from patients by semi-structured interview and hospital medical records. Pre-hospital delay (median and inter-quartile range) was calculated. Statistical significance was determined by Chi-square test. Multivariate logistic regression analysis was done to determine the independent predictors of pre-hospital delay. Results The mean age of the respondents was 53.8±11.2 years. Two-thirds (67.6%) of the respondents were males. Median total pre-hospital delay was 11.5 (IQR-18.3) hours with median decision time from symptom onset to seeking medical care being 3.0 (IQR: 11.0) hours. Nearly half (48.9%) of patients presented to the hospital more than 12 hours after symptom onset. On multivariate logistic regression analysis, AMI patients with absence of typical chest pain [OR 5.21; (95% CI: 2.5–9.9)], diabetes [OR: 1.7 (95% CI: 1.0–2.9)], residing/staying > 30 km away from nearest hospital at the time of onset [OR: 4.3(95% CI = 2.3–7.2)] and belonged to lower and middle class [OR: 1.9(95% CI = 1.0–3.5)] were significantly associated with pre-hospital delays. Conclusion Acute myocardial infarction (AMI) patients with atypical chest pain, diabetes, staying far away from nearest hospital and belonged to lower and middle socioeconomic strata were significantly associated with pre-hospital delays. The findings could have immense implications for improvements about timely reaching of AMI patients to the hospital within the context of their sociodemographic status and geographic barriers of the city.

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Illness prevalence rate in Tibet, China: Data from the 2018 National Health Service Survey

10.21203/rs.2.14864/v3 ◽

2020 ◽

Author(s):

Rendan Deng ◽

Laba sangzhu ◽

Zhaxi deji ◽

Guihua Wang ◽

Peiwei Hong ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Health Status ◽

National Health Service ◽

Health Service ◽

Logistic Regression Analysis ◽

Prevalence Rate ◽

Multivariate Logistic Regression Analysis ◽

Service Needs ◽

Multivariate Logistic Regression

Abstract Abstract Background Tibet is located in the high-altitude area of Southwest China, where the health level is influenced by specific factors such as the natural environment and living habits. However, there has been little research that has focused on Tibetan health conditions. The two-week prevalence rate is an important indicator of the health level of residents. The purpose of this study was to understand the health status of the residents and the health service needs in Tibet. Methods The two-week prevalence rate was calculated using data from a population of 10,493 individuals aged 15 and above that was obtained from the 2018 Sixth National Health Service Survey of Tibet. We initially analysed the types and associated factors of two-week illnesses in Tibetan. The influencing factors for the two-week prevalence rate in Tibet were determined by multivariate logistic regression analysis. Subsequently, we assessed the severity of two-week illnesses by calculating the average days of the duration of the disease, the days of being bedridden and the days of being off work. Results The two-week illness prevalence rate was 20.1% in Tibet. Digestive system diseases were frequent, and hypertension was the most common disease. According to the multivariate logistic regression analysis, the two-week prevalence rate was associated with gender, age, residence, marital status, and employment status. In addition, the severity of two-week illnesses differed among the residents. Conclusion This study identified that health service needs have increased in Tibet and that the health status of the local residents needs to be improved. Moreover, hypertension has become a major health hazard for the residents and should be considered in the utilization of health services.

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Association Between Cognitive Decline and Oral Health Status in the Aging Population

GeroPsych ◽

10.1024/1662-9647/a000271 ◽

2021 ◽

Author(s):

Swapnil Sunil Bumb ◽

Charu Chitra Govindan ◽

Safalya S. Kadtane ◽

Roshani Chawla ◽

Ruchika Gupta ◽

...

Keyword(s):

Older Adults ◽

Logistic Regression ◽

Regression Analysis ◽

Health Status ◽

Oral Health ◽

Cognitive Function ◽

Cognitive Decline ◽

Logistic Regression Analysis ◽

Oral Health Status ◽

Health Examination

Abstract. Background: To date, no longitudinal prospective study has investigated the association between oral health status and cognitive decline in the geriatric Indian population, possibly because past studies differed in their target groups and methodologies. We investigated the association between tooth loss, as evaluated through clinical oral examinations, and the development of cognitive decline in older adults while considering baseline cognitive function. Objectives: This study served to find an association between oral health status and the subsequent development of cognitive decline in older adults of Maharashtra state while considering baseline cognitive function. Material and Methods: This 5-year prospective cohort study followed 140 participants without cognitive impairment aged ≥ 65 years (mean age: 70.9 ± 4.3 years) living in the Dhule region of Maharashtra, India. Cognitive function was evaluated with the Mini-Mental State Examination (MMSE) in baseline and follow-up surveys, while oral health examination was carried out using Oral Hygiene Index. To investigate the association between oral health status and cognitive decline, we applied a multiple logistic regression analysis adjusted for age, sex, hypertension, diabetes, cerebrovascular/cardiovascular disease, hypercholesterolemia, depressive symptoms, body mass index, smoking status, drinking status, duration of education, and baseline MMSE score. Results: In the 5 years after the baseline survey, we obtained an overall incidence of 20.71% in the population that developed cognitive decline (i.e., MMSE scores of ≤ 24). A multivariable logistic regression analysis indicated that participants with compromised oral health were more likely to develop cognitive decline than those with mild to moderate oral health were (odds ratio: 3.31; 95% confidence interval: 1.07–10.2). Age, male sex, and baseline MMSE scores were also significantly associated with cognitive decline. Conclusion: Among the geriatric population of India, poor oral health status was independently associated with the development of cognitive decline within 5 years. This finding corroborates the hypothesis that oral health may be a predictor or risk factor for cognitive decline.

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Illness prevalence rate in Tibet, China: Data from the 2018 National Health Service Survey

10.21203/rs.2.14864/v4 ◽

2020 ◽

Author(s):

Rendan Deng ◽

Laba sangzhu ◽

Zhaxi deji ◽

Guihua Wang ◽

Peiwei Hong ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Health Status ◽

National Health Service ◽

Health Service ◽

Logistic Regression Analysis ◽

Prevalence Rate ◽

Multivariate Logistic Regression Analysis ◽

Service Needs ◽

Multivariate Logistic Regression

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Efficacy of flurbiprofen axetil for preventing postanesthetic shivering in patients undergoing gynecologic laparotomy surgeries

JA Clinical Reports ◽

10.1186/s40981-020-00403-x ◽

2020 ◽

Vol 6 (1) ◽

Author(s):

Atsushi Kotera

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Postoperative Pain ◽

Logistic Regression Analysis ◽

Pain Control ◽

Multivariate Logistic Regression Analysis ◽

Multivariate Logistic Regression ◽

Postoperative Pain Control ◽

Flurbiprofen Axetil ◽

Postanesthetic Shivering

Abstract Background Postanesthetic shivering is an unpleasant adverse event in surgical patients. A nonsteroidal anti-inflammatory drug has been reported to be useful in preventing postanesthetic shivering in several previous studies. The aim of this study was to evaluate the efficacy of flurbiprofen axetil being a prodrug of a nonsteroidal anti-inflammatory drug for preventing postanesthetic shivering in patients undergoing gynecologic laparotomy surgeries. Method This study is a retrospective observational study. I collected data from patients undergoing gynecologic laparotomy surgeries performed between October 1, 2019, and September 30, 2020, at Kumamoto City Hospital. All the patients were managed with general anesthesia with or without epidural analgesia. The administration of intravenous 50 mg flurbiprofen axetil for postoperative pain control at the end of the surgery was left to the individual anesthesiologist. The patients were divided into two groups: those who had received intravenous flurbiprofen axetil (flurbiprofen group) and those who had not received intravenous flurbiprofen axetil (non-flurbiprofen group), and I compared the frequency of postanesthetic shivering between the two groups. Additionally, the factors presumably associated with postanesthetic shivering were collected from the medical charts. Intergroup differences were assessed with the χ2 test with Yates’ correlation for continuity category variables. The Student’s t test was used to test for differences in continuous variables. Furthermore, a multivariate logistic regression analysis was performed to elucidate the relationship between the administration of flurbiprofen axetil and the incidence of PAS. Results I retrospectively examined the cases of 141 patients aged 49 ± 13 (range 21-84) years old. The overall postanesthetic shivering rate was 21.3% (30 of the 141 patients). The frequency of postanesthetic shivering in the flurbiprofen group (n = 31) was 6.5%, which was significantly lower than that in the non-flurbiprofen group (n = 110), 25.5% (p value = 0.022). A multivariate logistic regression analysis showed that administration of flurbiprofen axetil was independently associated with a reduced incidence of postanesthetic shivering (odds ratio 0.12; 95% confidence interval, 0.02-0.66, p value = 0.015). Conclusions My result suggests that intraoperative 50 mg flurbiprofen axetil administration for postoperative pain control is useful to prevent postanesthetic shivering in patients undergoing gynecologic laparotomy surgeries.

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