scholarly journals The impact of vitamin E and/or selenium dietary supplementation on growth parameters and expression levels of the growth-related genes in broilers

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Olla A. Khalifa ◽  
Rasha A. Al Wakeel ◽  
Shabaan A. Hemeda ◽  
Mohamed M. Abdel-Daim ◽  
Ghadeer M. Albadrani ◽  
...  
Keyword(s):  
Health Status ◽  
Vitamin E ◽  
Liver Tissue ◽  
General Health ◽  
Dietary Supplementation ◽  
Production Performance ◽  
Poultry Production ◽  
General Health Status ◽  
Production Parameters ◽  
The Impact

Abstract Background Broilers are continuously stressed because of the rapid growth rate and the environmental issues associated with industrialized poultry production systems, which lead to higher susceptibility for infection with pathogens. It is well known that vitamin E (Vit. E) and selenium (Se) supplementation have protective functions in such stressful conditions. This protocol was to investigate the impact of Vit. E and/or Se on the production performance, some serum biochemistry, and expression of some growth-related gene in the liver tissue of the broilers. The day-old chicks were allotted into four groups according to the supplement; Control group and groups supplemented with Vit. E and/or Se into Vit. E group (100 mg Vit. E/kg diet), Se group (0.3 mg sodium selenite/kg diet), and Vit E + Se group that supplemented with both Vit. E and Se. Results The data of the present experiment showed that dietary inclusion of Vit. E and/or Se significantly (P ≤ 0.05) improved the production parameters without any side effect on the general health status of the broilers, which indicated by normal serum biochemical parameters. Moreover, the treatments positively affected the expression of some genes related to growth performance including growth hormone receptor (GHR) and insulin-like growth factor 1 (IGF1) in the liver tissue of broilers. Conclusion Dietary supplementation of Vit. E and/or Se improved the production parameters and upregulate the growth-related genes without effect on the general health status of the broilers.

scholarly journals Patient-reported outcome scores underestimate the impact of major complications in patients undergoing spine surgery for degenerative conditions

2017 ◽  
Vol 27 (4) ◽  
pp. 397-402 ◽  
Author(s):  
Borys V. Gvozdyev ◽  
Leah Y. Carreon ◽  
Christopher M. Graves ◽  
Stephanie A. Riley ◽  
Katlyn E. McGraw ◽  
...  
Keyword(s):  
Health Status ◽  
Spine Surgery ◽  
General Health ◽  
Major Complication ◽  
Adverse Outcomes ◽  
General Health Status ◽  
Major Complications ◽  
Significant Difference ◽  
Patient Reported ◽  
The Impact

OBJECTIVEPatient-reported outcomes (PROs) such as the Oswestry Disability Index (ODI) and EuroQol-5D (EQ-5D) are widely used to evaluate treatment outcomes following spine surgery for degenerative conditions. The goal of this study was to use the Charlson Comorbidity Index (CCMI) as a measure of general health status, for comparison with standard PROs.METHODSThe authors examined serial CCMI scores, complications, and PROs in 371 patients treated surgically for degenerative lumbar spine conditions who were enrolled in the Quality and Outcomes Database from a single center. The cohort included 152 males (41%) with a mean age of 58.7 years. Patients with no, minor, or major complications were compared at baseline and at 1 year postoperatively.RESULTSMinor complications were observed in 177 patients (48%), and major complications in 34 (9%). There were no significant differences in preoperative ODI, EQ-5D, or CCMI among the 3 groups. At 1 year, there was a significantly greater deterioration in CCMI in the major complication group (1.03) compared with the minor (0.66) and no complication groups (0.44, p < 0.006), but no significant difference in ODI or EQ-5D.CONCLUSIONSDespite equivalent improvements in PROs, patients with major complications actually had greater deterioration in their general health status, as evidenced by worse CCMI scores. Because CCMI is predictive of medical and surgical risk, patients who sustained a major complication now carry a greater likelihood of adverse outcomes with future interventions, including subsequent spine surgery. Although PRO scores are a key metric, they fail to adequately reflect the potential long-term impact of major perioperative complications.

scholarly journals Does Hallux Rigidus produce worse functional disability than Hallux Valgus?

2018 ◽  
Vol 3 (3) ◽  
pp. 2473011418S0044
Author(s):  
Malik Siddique ◽  
Jayasree Ramaskandhan ◽  
Sultan Qasim
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Hallux Valgus ◽  
General Health ◽  
Functional Disability ◽  
Hallux Rigidus ◽  
Foot And Ankle ◽  
General Health Status ◽  
The Impact

Category: Midfoot/Forefoot Introduction/Purpose: There is paucity of literature comparing foot and general health status including quality of life between patients presenting with Hallux Valgus and Hallux Rigidus. We aimed to compare foot specific patient reported disability and general health status including higher functional activities and quality of life reported between patients presenting with Hallux Valgus and Hallux Rigidus. Methods: All patients who presented at our hospital foot and ankle clinics (between June 2016 and December 2017) with a diagnosis of primary Hallux Valgus or Hallux Rigidus were included in this prospective study. Patients with associated foot problems, bilateral presentations, h/o previous reconstructive surgeries, and underlying neurological conditions were excluded. These patients were grouped based on diagnosis into Group A (Hallux Valgus) and Group B (Hallux Rigidus). In these patients, differences were studied between groups for scores of MOX-FQ Manchester-Oxford foot questionnaire (Domains: Pain, Walking/Standing, Social activities), EQ-5D EuroQol (UK) and Foot and Ankle outcomes scores (FAOS) (Domains: Pain, symptoms, ADL, Recreation, Quality of Life). Statistical tests between groups included tests for normality, student t’tests and chi square tabulation tests using SPSS software. Results: MOX-FQ differences: -  Both groups reported similar level of pain (59.6 ± 22.6 vs. 58.2 ± 23.3); p=0.776; Difficulty with walking/ standing (61.6 vs. 61.4 ); p= 0.960; and restriction with social activity because of foot symptoms (61.6 vs. 59.7 ); p=0.683 EQ-5D: -  For mobility, both groups reported no (21.7% vs. 26.8); slight (28.2% vs. 29.2%) or moderate (34.7% vs. 31.7%) problems; p=0.931. For self-care, pain/discomfort, anxiety/ depression levels, there was no differences between groups; p>0.05. Mean overall general health scores was (71.3 ± 22.8) and (69.5 ± 20.8); p=0.663 FAOS: -  There was no difference in mean pain score (59.6 vs. 58.2; p=0.776), symptoms (70.3 vs. 63.8; p=0.104), ADL score (p=0.587), difficulty with sport/ recreation (p=0.907) or Quality of Life (p=0.662) between groups Conclusion: -  There is no difference in foot related quality of life, general health status and higher functional disability levels between patients presenting with Hallux Valgus vs. Hallux Rigidus. -  The impact of these conditions on disability levels remain the same, amidst the difference in pathology

scholarly journals The Impact of Fatigue on Patients with Multiple Sclerosis

1994 ◽  
Vol 21 (1) ◽  
pp. 9-14 ◽  
Author(s):  
John D. Fisk ◽  
Amanda Pontefract ◽  
Paul G. Ritvo ◽  
Catherine J. Archibald ◽  
T.J. Murray
Keyword(s):  
Mental Health ◽  
Health Status ◽  
General Health ◽  
General Health Status ◽  
Severe Problem ◽  
Hypertensive Patients ◽  
Neurologic Impairment ◽  
Impact Scale ◽  
Fatigue Impact Scale ◽  
The Impact

ABSTRACT:Although fatigue is recognized as a symptom of MS, there have been insufficient methods for evaluating this symptom. We administered the Fatigue Impact Scale to 85 MS patients and 20 hypertensive patients. Neurologic impairment, mental health, and general health status were also assessed. MS patients reported significantly higher fatigue impact than hypertensive patients. Most MS patients reported fatigue as either their worst (14%), or one of their worst (55%) symptoms. Disease classification and neurologic impairment had little bearing on Fatigue Impact Scale scores in the MS sample. The best predictive models for mental health and general health status in the MS sample both included the Fatigue Impact Scale as a significant factor. This study demonstrates that: 1) fatigue is a very prevalent and severe problem in MS, 2) fatigue impact cannot be predicted by clinical measures of neurologic impairment, 3) fatigue has a significant effect on the mental health and general health status of MS patients.

scholarly journals Factors associated with perceived stress of clinical practice among associate degree nursing students in Taiwan

2021 ◽  
Author(s):  
Chia-Shan Wu ◽  
Jiin-Ru Rong ◽  
Mei-zen Huang
Keyword(s):  
Clinical Practice ◽  
Health Status ◽  
Nursing Students ◽  
Perceived Stress ◽  
General Health ◽  
Mild Stress ◽  
General Health Status ◽  
Cross Sectional ◽  
Factors Associated ◽  
The Impact

Abstract BackgroundClinical placements play an important role in helping nursing students to achieve clinical competence, but these placements can be highly challenging and stressful. It has been shown that stress can be either a trigger or aggravating factor for ill-health in general, but studies have seldom differentiated the impact of general health status on perceived stress. This study examined factors associated with perceived stress of clinical practice among nursing students with a particular focus on the effect of general health status on stress.MethodsThis was a cross-sectional quantitative study conducted among 724 associate nursing degree students in Southern Taiwan. ResultsHealth status scores varied from 28-139, with an average of 68.40 (SD = 25.75). Health status was reported to be ‘good’ (scores 28-55) in 35.5% of participants, moderate (scores 56–83) in 24.6%, and poor (Scores ≧ 84) in 39.9% of participants. Perceived stress scores ranged from 0-95 points with an average score of 36.65 (SD ± 15.95). The CART analysis showed health status as the most important factor linked to perceived stress with a Normalized Importance value of 100%. Those who reported general health status (measured through GHQ-28 ) score of ≤ 34.5 perceived mild stress and those with a score of >34.5–<84.5 perceived moderate stress. A score of 84.5 was found to be the point of transition to perceptions of severe stress. When health status score was greater than 84.5, perceived stress was at a severe or extremely severe level. ConclusionsOur findings indicated health status as a potential measure to identify students who were most vulnerable to perceived stress. Given the cross-sectional design of this study and the bidirectional relationship between health and stress, more studies are needed to fully establish the predictive link between general health status and vulnerability to stress.

scholarly journals The health situation of children and adolescents with migration background in Germany

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
C Santos-Hövener ◽  
B Kuntz ◽  
L Frank ◽  
C Koschollek ◽  
U Ellert ◽  
...  
Keyword(s):  
Health Status ◽  
Length Of Stay ◽  
Children And Adolescents ◽  
General Health ◽  
Migration Background ◽  
General Health Status ◽  
Health Differences ◽  
Per Se ◽  
Health Situation ◽  
The Impact

Abstract Introduction Although more than one third of minors living in Germany have a migration background (MB), valid data on the health of this population are still lacking. The German Health Interview and Examination Survey for Children and Adolescents in Germany (KiGGS wave 2, 2014-2017) provides population-based data to make reliable statements on the health of adolescents with and without MB. Methods Survey data from KiGGS wave 2 are used to describe the general health status, mental health and the prevalence of allergic diseases in 3-to 17-year-old children and adolescents (n = 13,568). To determine overweight, body height and weight are measured (n = 3,463). In addition to MB (without/one-sided/two-sided), the socio-economic status (SES) and the length of stay of the parents in Germany are taken into account. Results Children and adolescents with two-sided MB show a physician-diagnosed atopic dermatitis (3.5%vs.6.9%) and attention deficit hyperactivity disorder (ADHD) (1.5%vs.5.1%) less frequently than their peers without MB, but more often a moderate or poor general health status (6.1%vs.3.9%). Adolescents with two-sided MB are also more often affected by overweight than those without MB (22.1%vs.12.2%). If only participants with MB are considered, their health situation is often associated with the SES and partly also with the length of stay of the parents. Discussion Health differences between children and adolescents with and without MB vary by the observed indicator. The heterogeneity of children and adolescents with MB, which can be partly determined by the SES or the length of stay of the parents, should be considered in target-group-specific interventions. Main messages The vast majority of children and adolescents in Germany grow up healthy and a MB is not per se associated with a poorer health status. Our results suggest that considering MB as the sole determinant of health to reflect the impact of migration on health is insufficient. Key messages Migration background is not per se associated with a poorer health status. Socioeconomic status and parents’ length of stay are derminants associated with poorer health outcomes among children and adolescents with migration background.

Impact of Severe Acute Respiratory Syndrome Care on the General Health Status of Healthcare Workers in Taiwan

2007 ◽  
Vol 28 (1) ◽  
pp. 75-79 ◽  
Author(s):  
Ning-Hung Chen ◽  
Pa-Chun Wang ◽  
Meng-Jer Hsieh ◽  
Chung-Chi Huang ◽  
Kuo-Chin Kao ◽  
...  
Keyword(s):  
Mental Health ◽  
Health Status ◽  
Severe Acute Respiratory Syndrome ◽  
General Health ◽  
Healthcare Workers ◽  
Control Group ◽  
General Health Status ◽  
After Care ◽  
Contact Hours ◽  
The Impact

Background.The impact of the outbreak of severe acute respiratory syndrome (SARS) was enormous, but few studies have focused on the infectious and general health status of healthcare workers (HCWs) who treated patients with SARS.Design.We prospectively evaluated the general health status of HCWs during the SARS epidemic.The Medical Outcome Study Short-Form 36 Survey was given to all HCWs immediately after caring for patients with SARS and 4 weeks after self-quarantine and off-duty shifts. Tests for detection of SARS Coronavirus antibody were performed for HCWs at these 2 time points and for control subjects during the SARS epidemic.Setting.Tertiary care referral center in Taipei, Taiwan.Subjects.Ninety SARS-care task force members (SARS HCWs) and 82 control subjects.Results.All serum specimens tested negative for SARS antibody. Survey scores for SARS HCWs immediately after care were significantly lower than those for the control group (P < .05 by the t test) in 6 categories. Vitality, social functioning, and mental health immediately after care and vitality and mental health after self-quarantine and off-duty shifts were among the worst subscales. The social functioning, role emotional, and role physical subscales significantly improved after self-quarantine and off-duty shifts (P < .05, by paired t test). The length of contact time (mean number of contact-hours per day) with patients with SARS was associated with some subscales (role emotional, role physical, and mental health) to a mild extent. The total number of contact-hours with symptomatic patients with SARS was a borderline predictor (adjusted R2 = 0.069; P = .038) of mental health score.Conclusions.The impact of the SARS outbreak on SARS HCWs was significant in many dimensions of general health. The vitality and mental health status of SARS HCWs 1 month after self-quarantine and off-duty shifts remained inferior to those of the control group.

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