Airway obstruction as the primary manifestation of infantile thyroid hemangioma

Abstract Background Thyroid hemangioma mostly occurs in adults and is extremely rare in infants. So far, only four pediatric cases of thyroid hemangioma have been reported, one of which has only been clinically diagnosed. Most of the reported cases are of cavernous hemangiomas; capillary hemangioma cases are very rare. To date, there are no reports on capillary thyroid hemangioma in an infant. Therefore, here we present the case of an infant with a primary capillary hemangioma of the thyroid gland, and discuss its treatment and follow-up. Case presentation A2-month-old infant with normal thyroid function presented with airway obstruction as the primary manifestation of thyroid hemangioma. The main symptoms were laryngeal wheezing and dyspnea. Ultrasonography revealed hypoechoic lesions at the lower pole of the bilateral thyroid. Computed tomography revealed enlargement of the thyroid gland, inhomogeneous parenchyma enhancement, and multiple thyroid nodules. However, these imaging modalities were unable to provide an exact diagnosis and the nature of the mass remained unknown prior to an operation. Therefore, a postoperative histopathological examination was undertaken, which revealed capillary thyroid hemangioma. The symptoms significantly improved by a combined treatment involving surgery and oral propranolol. Conclusion When a well-defined capsulate mass is detected on the medical image, the possibility of primary thyroid hemangioma must be considered.

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Airway Obstruction as the Primary Manifestation of Infantile Thyroid Hemangioma: A Case Report and Literature Review

10.21203/rs.3.rs-39632/v2 ◽

2020 ◽

Author(s):

Yujian Liang ◽

Ronghui Pu ◽

Xueqiong Huang ◽

Suping Li ◽

Yingqian Chen ◽

...

Keyword(s):

Thyroid Gland ◽

Airway Obstruction ◽

Histopathological Examination ◽

Combined Treatment ◽

Capillary Hemangioma ◽

Case Presentation ◽

Normal Thyroid Function ◽

Cavernous Hemangiomas ◽

Parenchyma Enhancement

Abstract Background: Thyroid hemangioma mostly occurs in adults and is extremely rare in infants. So far, only four pediatric cases of thyroid hemangioma have been reported, one of which has only been clinically diagnosed. Most of the reported cases are of cavernous hemangiomas; capillary hemangioma cases are very rare. To date, there are no reports on capillary thyroid hemangioma in an infant. Therefore, here we present the case of an infant with a primary capillary hemangioma of the thyroid gland, and discuss its treatment and follow-up. Case Presentation: A 2-month-old infant with normal thyroid function presented with airway obstruction as the primary manifestation of thyroid hemangioma. The main symptoms were laryngeal wheezing and dyspnea. Ultrasonography revealed hypoechoic lesions at the lower pole of the bilateral thyroid. Computed tomography revealed enlargement of the thyroid gland, inhomogeneous parenchyma enhancement, and multiple thyroid nodules. However, these imaging modalities were unable to provide an exact diagnosis and the nature of the tumor remained unknown prior to an operation. Therefore, a postoperative histopathological examination was undertaken, which revealed capillary thyroid hemangioma. The symptoms significantly improved by a combined treatment involving surgery and oral propranolol (2 mg/kg per day). Conclusion: When a well-defined capsulate mass is detected on the medical image, the possibility of primary thyroid hemangioma must be considered.

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Airway Obstruction as the Primary Manifestation of Infantile Thyroid Hemangioma: A Case Report and Literature Review

10.21203/rs.3.rs-39632/v1 ◽

2020 ◽

Author(s):

Yujian Liang ◽

Ronghui Pu ◽

Xueqiong Huang ◽

Suping Li ◽

Yingqian Chen ◽

...

Keyword(s):

Thyroid Gland ◽

Airway Obstruction ◽

Thyroid Nodules ◽

Histopathological Examination ◽

Combined Treatment ◽

Capillary Hemangioma ◽

Normal Thyroid Function ◽

Cavernous Hemangiomas ◽

Parenchyma Enhancement ◽

Oral Propranolol

Abstract Background: Thyroid hemangioma mostly occurs in adults and is extremely rare in infants. So far, only four pediatric cases of thyroid hemangioma have been reported, one of which has only been clinically diagnosed. Most of the reported cases are of cavernous hemangiomas; capillary hemangioma cases are very rare. To date, there are no reports on capillary thyroid hemangioma in an infant. Therefore, here we present the case of an infant with a primary capillary hemangioma of the thyroid gland, and discuss its treatment and follow-up.Case Presentation: A 2-month-old infant with normal thyroid function presented with airway obstruction as the primary manifestation of thyroid hemangioma. The main symptoms were laryngeal wheezing and dyspnea. Ultrasonography revealed hypoechoic lesions at the lower pole of the bilateral thyroid. Computed tomography revealed enlargement of the thyroid gland, inhomogeneous parenchyma enhancement, and multiple thyroid nodules. However, these imaging modalities were unable to provide an exact diagnosis and the nature of the tumor remained unknown prior to an operation. Therefore, a postoperative histopathological examination was undertaken, which revealed capillary thyroid hemangioma. The symptoms significantly improved by a combined treatment involving surgery and oral propranolol (2 mg/kg per day).Conclusion: When a well-defined capsulate mass is detected on the medical image, the possibility of primary thyroid hemangioma must be considered.

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Intrasellar Cavernous Hemangioma, a Rare Condition Causing Both Radiological And Clinical Difficulties- a Case Report

Journal of the Endocrine Society ◽

10.1210/jendso/bvab048.1202 ◽

2021 ◽

Vol 5 (Supplement_1) ◽

pp. A589-A590

Author(s):

Andrzej Jerzy Nowak ◽

Anna Grochowska ◽

Dariusz Adamek ◽

Magdalena Godlewska ◽

Marcin Motyka ◽

...

Keyword(s):

Optic Nerve ◽

Cavernous Sinus ◽

Cavernous Hemangioma ◽

Histopathological Examination ◽

Sella Turcica ◽

Tumor Board ◽

Oculomotor Nerve Palsy ◽

Tumor Mass ◽

Cavernous Hemangiomas

Abstract Introduction: Intrasellar cavernous hemangiomas constitute an extremely rare group of findings in endocrinological practice. Diagnosis remains challenging due to non-characteristic symptoms and neuroradiological features which may resemble those of pituitary adenomas. Presentation of the Case: We present a case of female born in 1941, diagnosed with a hemangioma cavernosum located in the Sella turcica. In 2004 our patient presented with uncharacteristic symptoms: syncopes and chronic headaches. Computed tomography (CT) of the head revealed an intrasellar hyperdense tumor mass with radiological features suggesting a pituitary adenoma. In 2005 the patient underwent transcranial resection of the sellar mass, with subsequent oculomotor nerve palsy. In histopathological examination, diagnosis of cavernous hemangioma was determined. Between 2005 and 2020 patient was asymptomatic, with multiple follow-up head MRIs scans, showing gradual progression in size of the intrasellar tumor. The patient was consulted by a neurosurgeon, with no direct indications for surgical approach found. Furthermore, due to suprasellar expansion into the direct proximity of the right optic nerve, the patient was disqualified for Gamma-Knife radiotherapy. The last MRI of the hypothalamic-pituitary area in 2020 revealed a polycyclic, homogeneous, 33x31x29 mm mass, filling in the space of the Sella turcica, with strong enhancement after contrast administration. Invasion of the surrounding structures, including the clivus, right cavernous sinus and right trigeminal cave were described. Bilaterally, internal carotid arteries and right optic nerve adhered directly to the lesion. Pituitary gland was compressed by the tumor mass. In July 2020, in order to verify the ambiguous radiological and clinical characteristics of the lesion including tumor regrowth and its invasiveness, a transsphenoidal partial resection was performed. Tissue samples were collected for the histopathological examination, which confirmed the initial diagnosis of cavernous hemangioma originating from the cavernous sinus. During a multidisciplinary tumor board, having taken into consideration relatively stable clinical condition and high risk possible surgical complications, the patient was currently disqualified from neurosurgical re-operation nor radiotherapy. Surprisingly, during whole follow up, patients pituitary function remained unimpaired. A watchful waiting approach, with radiological and endocrinological follow up were scheduled. Conclusion: To date, only few cases of intrasellar cavernous hemangiomas have been reported. Intrasellar hemangiomas may originate from the vascular tissue of the cavernous sinus. Surgical removal remains the recommended treatment modality, but radiosurgery could be a therapeutic option as well. Stable patients with no clinical symptoms may remain in observation.

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An Unusual Histology for a Lung Nodule: A Case Report of Primary Pulmonary Paraganglioma

Frontiers in Surgery ◽

10.3389/fsurg.2021.688236 ◽

2021 ◽

Vol 8 ◽

Author(s):

Alessandra Mazzucco ◽

Eleonora Poirè ◽

Andrea Leporati ◽

Matteo Chiari ◽

Laura Moneghini ◽

...

Keyword(s):

Clinical Presentation ◽

Histopathological Examination ◽

Incidental Finding ◽

Lung Nodule ◽

Pulmonary Tissue ◽

Case Presentation ◽

X Ray ◽

Asymptomatic Patients ◽

Chest X Ray

Introduction: Primary pulmonary paraganglioma is a rare tumor with few cases reported in literature and unspecific clinical presentation.Case Presentation: A 49-year-old woman presented to our department with an incidental finding of a pulmonary mass at chest X-ray and no associated clinical symptom. The CT scan and the FDG-PET showed mild uptake of contrast, but a definitive diagnosis was only possible after surgery through histopathological examination.Conclusion: Paragangliomas originating in the pulmonary tissue are generally non-functioning masses discovered incidentally in otherwise asymptomatic patients. Surgery appears to be the best treatment option, with only radiologic follow-up necessary afterwards.

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Malignant Mesothelioma of the Epididymis: A Case Report of a Rare Paratesticular Neoplasm and Literature Review

Surgical Case Reports ◽

10.31487/j.scr.2020.12.16 ◽

2020 ◽

pp. 1-3

Author(s):

Jasser Maatougui ◽

Mehdi Raboudi ◽

Tarek Taktak ◽

Issam Msakni ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Malignant Mesothelioma ◽

Poor Prognosis ◽

Histopathological Examination ◽

Multidisciplinary Management ◽

Case Presentation ◽

Scrotal Ultrasound ◽

Disease Free

Background: Malignant mesothelioma of the epididymis is an extremely rare neoplasm with a poor prognosis and high potential of recurrence. Case Presentation: We report a case of a 28-year-old male with a left painless epididymal nodule. Scrotal ultrasound revealed a nodular mass with mixed echogenicity and Doppler showed increased vascularity. Radical orchidectomy was performed. Histopathological examination concluded to a malignant mesothelioma involving the epididymis. Metastatic workup was negative. The patient has undergone a regular follow-up and has been disease-free within 6 months. Conclusion: Malignant mesothelium of the epididymis is a diagnosis challenge. Surgery remains the main treatment. A multidisciplinary management should be offered in those cases.

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Intracranial Capillary Hemangioma – a Case Report and Literature Review

10.21203/rs.3.rs-465931/v1 ◽

2021 ◽

Author(s):

Aimee Goel ◽

Hadleigh Cuthbert ◽

Jooly Joseph ◽

Erminia Albanese

Keyword(s):

Literature Review ◽

Soft Tissues ◽

Capillary Hemangioma ◽

En Bloc ◽

Complete Excision ◽

Case Presentation ◽

Tentorial Meningioma ◽

The Central Nervous System ◽

One Year

Abstract BackgroundCapillary hemangiomas of the central nervous system are exceedingly rare. These are benign tumour-like lesions that usually occur in the skin and soft tissues of mainly children. We report the case of an extra-axial capillary hemangioma mimicking a tentorial meningioma.Case presentationA 46-year old female patient presented with headaches. Imaging revealed an avidly enhancing tentorial lesion with a wide dural base, features suggestive of a meningioma. Intra-operatively, an extra-axial heavily vascular tumour was found and was radically resected en bloc. Histology revealed thin-walled capillary-sized vessels arranged in closely packed lobules, and a diagnosis of capillary hemangioma was made. At one year follow up, the patient was asymptomatic and no tumour recurrence was noted.ConclusionsA literature review showed that capillary hemangiomas may be misdiagnosed as other extra-axial dural-based lesions such as meningiomas, schwannomas, hemangiopericytomas and inflammatory granulomatous lesions. Diagnosis should be considered especially in radiologically atypical cases. Complete excision is curative. Stereotactic radiosurgery on its own or in conjunction with surgery also achieves good results while partial excision or biopsy alone often leads to recurrence.

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Functional and Esthetic Correction of Severe Localized Pregnancy-Induced Gingival Enlargement associated with Capillary Hemangioma

International Healthcare Research Journal ◽

10.26440/ihrj/01_08/124 ◽

2017 ◽

Vol 1 (8) ◽

pp. 248-251

Author(s):

Pawan Kumar ◽

Saindhya Tora Sonowal ◽

Jitu Chawla

Keyword(s):

Rare Case ◽

Histopathological Examination ◽

Immunological Response ◽

Surgical Excision ◽

Capillary Hemangioma ◽

Anterior Maxilla ◽

Attached Gingiva ◽

Gingival Enlargement ◽

Rare Case Report

Gingival enlargement is a clinical condition that has been directly associated with specific local or systemic conditions. Pregnancy has been considered an attributing factor which increases the susceptibility to gingival enlargement. It is also considered as a risk factor for periodontitis because of its ability to allow proliferation of specific microorganisms and affect host immunological response. This paper presents a rare case report of capillary hemangioma on attached gingiva of anterior maxilla in an adult female which initiated when she was in her 10th week of gestation. After parturition, gingival enlargement further progressed and caused functional and aesthetic problem. Enlargement did not resolve even after non-surgical therapy; therefore, surgical excision of the entire enlargement was preformed. Histopathological examination revealed capillary hemangioma. No evidence of malignancy was seen. No recurrence was seen even after 2 years of follow-up.

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Paediatric RCC with sarcomatoid variation: a rare entity

African Journal of Urology ◽

10.1186/s12301-020-00101-1 ◽

2020 ◽

Vol 26 (1) ◽

Author(s):

Anuj Mahajan ◽

Prashanth Adiga ◽

Vivek Pai ◽

Keerthi Raj

Keyword(s):

Clear Cell ◽

Histopathological Examination ◽

Treatment Protocol ◽

Age Group ◽

Renal Masses ◽

Case Presentation ◽

Long Term Follow Up ◽

Paediatric Age

Abstract Background Malignant renal masses in paediatric age group are mostly Wilms’ tumour. RCC is very rare in this age group, papillary variant being the most common. Sarcomatoid variation occurs in 5% of adult RCC, while it is extremely rare in children. No treatment protocol exists in the management of paediatric RCC. Case presentation Here, we present a case of 10-year-old female who presented with left flank mass. Radical nephrectomy was done which showed clear cell carcinoma with sarcomatoid variant on histopathological examination. Conclusion RCC with sarcomatoid variation can occur in children. However, further studies and long-term follow-up are needed for formulating a treatment protocol and prognostication factors for the same.

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Schwannoma Located in Nasopharyngeal Region

Case Reports in Otolaryngology ◽

10.1155/2016/8260629 ◽

2016 ◽

Vol 2016 ◽

pp. 1-3

Author(s):

Fadlullah Aksoy ◽

Alper Yenigun ◽

Erol Senturk ◽

Orhan Ozturan

Keyword(s):

Peripheral Nerves ◽

Histopathological Examination ◽

Neck Region ◽

Case Presentation ◽

Head And Neck Region ◽

Nerve Sheath ◽

Swallowing Difficulties ◽

First Time ◽

Slow Growing

Schwannoma is a tumor which has neuroectoderm origins, is hard, well-circumscribed, encapsulated, and slow growing benign cranial tumor, and may autonomously grow out of the nerve sheath of peripheral nerves. It is mostly seen in the head and neck region. In the paranasal sinus and nose areas, it is seen at a rate of 4%. The diagnosis is mostly made after histopathological examination. In this paper, a Schwannoma case observed in the nasopharyngeal region was presented in a 20-year-old female who had complaints of sleeping with open mouth, snoring, foreign body feeling in throat, and swallowing difficulties. The tumor was extracted via transoral approach. No recurrence was observed during follow-up over the next year. This case presentation is presented for the first time in the literature in English.

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Hypothyroidism in surgically treated T4 hypopharyngeal and laryngeal cancers

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20174316 ◽

2017 ◽

Vol 3 (4) ◽

pp. 968

Author(s):

Deepak Janardhan ◽

Bipin T. Varghese ◽

Elizabeth Mathew Iype ◽

Shaji Thomas

Keyword(s):

Thyroid Gland ◽

Thyroid Function ◽

Total Laryngectomy ◽

Thyroid Dysfunction ◽

Histopathological Examination ◽

Post Treatment ◽

Considerable Proportion ◽

Thyroid Resection ◽

Operative Complications

Background: Total laryngectomy in laryngohypopharyngeal cancers, both in primary setting and salvage scenario, include variable amounts of thyroid resection. Although considerable proportion of these cases undergo total thyroidectomy, with an intention of wider surgical clearance, histopathological examination for thyroid infiltration, very often indicate that such resections are generally out of proportion to the actual oncological requirement.Methods: Forty three patients undergoing total laryngectomy with no prior thyroid dysfunction, from April 2014 to 2016, at our centre, were prospectively studied for post treatment, thyroid function with tests done at 6th month. Overt and occult hypothyroidism was correlated with extent of thyroid preserved intraoperatively. Results: Of 43 patients studied, 82% had extralaryngeal spread, and 16% of them showed thyroid gland infiltration. Only 7% were patholog1ically correlated for gland infiltration. Among those who had hemithyroidectomy, clinical hypothyroidism was seen in 20% primary and 85% salvage cases by 6th month of post treatment period.Conclusions: In clinicoradiologically favourable scenarios, thyroid preservation attempt helps to augment the neopharynx closure line and to preserve the parathyroids. Anatomical preservation however doesnot guarantee thyroid function, which needs regular follow up to avoid post-operative complications and better QOL.

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