scholarly journals A comparison of erythrocyte sedimentation rates of bloods anticoagulated with trisodium citrate and EDTA among TB presumptive patients at the University of Gondar comprehensive specialized hospital, northwest Ethiopia

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Zegeye Getaneh ◽  
Fekadu Ayelgn ◽  
Geletaw Asemahegn ◽  
Habtamu Geleta ◽  
Aregawi Yalew ◽  
...  
2020 ◽  
Author(s):  
Zegeye Getaneh ◽  
Fekadu Ayelgn ◽  
Geletaw Asemahegn ◽  
Habtamu Geleta ◽  
Aregawi Yalew ◽  
...  

Abstract Objective: The purpose of this study was comparing the erythrocyte sedimentation rate (ESR) results of trisodium citrate (TSC) and ethylene diamine tetra-acetic acid (EDTA) anticoagulants. A comparative cross-sectional study was conducted at the University of Gondar specialized referral hospital, northwest, Ethiopia. A total of 70 TB presumptive participants were recruited. From each of the 70 participants of the study, 3 and 1.6 ml of blood was collected in EDTA tubes and 0.4 ml of trisodium Citrate anticoagulant containing test tubes, respectively. Results: The mean ± SD values of ESR were 57.9 ± 41.45 mm/hr in EDTA and 50.99 ± 43.5 mm/hr in TSC anticoagulated blood. The mean difference of ESR values between EDTA and TSC blood (6.91 ± 13.66 mm/hr) was statistically significant. The Mean ± SD of ESR values using EDTA and TSC in males were 59.57 ± 42.31 and 53.57 ± 44.61 mm/hr while for females it was 54.71±40.44 and 46.04 ± 41.82 mm/hr, respectively. The study indicated that there was a significant difference between ESR values with EDTA and tri-sodium citrate anticoagulants. Keywords: Erythrocyte sedimentation rate, EDTA, Tri-sodium citrate, Westergren Method, Comparison


2020 ◽  
Author(s):  
Zegeye Getaneh ◽  
Fekadu Ayelgn ◽  
Geletaw Asemahegn ◽  
Habtamu Geleta ◽  
Aregawi Yalew ◽  
...  

Abstract Objective: The purpose of this study was comparing the erythrocyte sedimentation rate (ESR) results of trisodium citrate (TSC) and ethylene diamine tetra-acetic acid (EDTA) anticoagulants. A comparative cross-sectional study was conducted at the University of Gondar specialized referral hospital, northwest, Ethiopia. A total of 70 TB presumptive participants were recruited. From each of the 70 participants of the study, 3 and 1.6 ml of blood was collected in EDTA tubes and 0.4 ml of trisodium Citrate anticoagulant containing test tubes, respectively. Results: The mean ± SD values of ESR were 57.9 ± 41.45 mm/hr in EDTA and 50.99 ± 43.5 mm/hr in TSC anticoagulated blood. The mean difference of ESR values between EDTA and TSC blood (6.91 ± 13.66 mm/hr) was statistically significant. The Mean ± SD of ESR values using EDTA and TSC in males were 59.57 ± 42.31 and 53.57 ± 44.61 mm/hr while for females it was 54.71±40.44 and 46.04 ± 41.82 mm/hr, respectively. The study indicated that there was a significant difference between ESR values with EDTA and tri-sodium citrate anticoagulants. Keywords: Erythrocyte sedimentation rate, EDTA, Tri-sodium citrate, Westergren Method, Comparison


2021 ◽  
Vol 8 (4) ◽  
pp. 594
Author(s):  
Vikram Aglave ◽  
Shashank Nagendra ◽  
Pawan T. Ojha ◽  
Kamlesh A. Jagiasi ◽  
Sumit Kharat ◽  
...  

Takayasu arteritis is an uncommon inflammatory disease of vessels that preferentially affects the aorta and its major branches. It can be a potential cause of stroke in young adults. Current study included 7 patients aged between 18 to 48 years. Each patient had varying presentations of stroke with Takayasu’s arteritis along with other neurological symptoms. Four of the 7 patients presented with ischemic strokes, one with hemorrhagic stroke, one with TIAs and one with syncopal attacks. All the patients had elevated erythrocyte sedimentation rates. Five of the seven patients were treated with steroids and methotrexate. Two were treated with azathioprine and steroids. Antiplatelets were given for those patients who had strokes and TIAs. Our cases demonstrate that Takayasu arteritis can present with varying presentations including stroke. Thus, it is important to consider Takayasu’s arteritis as an unusual etiology of stroke especially in young adults.


1959 ◽  
Vol 196 (3) ◽  
pp. 473-477 ◽  
Author(s):  
Roy L. Swank

The effect of large butter-fat meals on the blood of rabbits and dogs has been studied. Marked distortion of the red blood cells with adhesiveness and aggregation was observed. This was accompanied by slowing of the circulation and by changes in the surface tension of the plasma. In addition changes in the platelet counts, white blood counts, hematocrit and erythrocyte sedimentation rates were observed. Changes were also noted in the buffy coat, in the clotting time and in the nature of the clot.


1976 ◽  
Vol 10 (1) ◽  
pp. 39-46 ◽  
Author(s):  
G. W. Tribe ◽  
A. E. Welburn

2 batches of baboon infected with tuberculosis were subjected to serial tests with human and bovine tuberculin, while erythrocyte sedimentation rates were estimated concurrently. In the very early stages most but not all reacted to human tuberculin while fewer responded to bovine material. After further development of the disease, tuberculin tests remained positive while sedimentation rates were raised by 10-30 mm per hour. By the time early spread had occurred response to tuberculin was absent but sedimentation rates tended to increase. Advanced cases were always tuberculin negative but sedimentation rates were in excess of 50 mm per hour. Such animals were always in good physical condition and represented an insidious danger to other animals and staff in contact with them. Clinical examination failed to reveal cases of tuberculosis except in the terminal stages and no cases were diagnosed by radiography. 2 animals died from apparent anaphylaxis following inoculation of both types of tuberculin. Results showed that use of one or other of these tests alone would not have made possible the elimination of infection.


1973 ◽  
Vol 51 (9) ◽  
pp. 685-690 ◽  
Author(s):  
R. N. O'Brien ◽  
M. B. Hocking ◽  
P. McOrmond ◽  
K. R. Thornton

The rates of erythrocyte settling have been investigated in round and square cross-section tubes, vertically; and at nine different angles; and with the square tubes flat and on edge, to a minimum of 15° from the horizontal. Apparent settling rates increased as the angle from the horizontal decreased. Real settling rates (vertical settling rates) increased sharply on decreasing the angle from the horizontal, to a maximum at about 60°, and then decreased less abruptly for the shallower angles. The cross-sectional shape of the tube did not significantly affect the settling rates of erythrocytes. Settling in inclined tubes proceeds fast enough to permit clinical erythrocyte settling rate (E.S.R.) tests to be carried out in 10 min in place of the usual 60 min. If the standard E.S.R. test rack deviates as little as 5° from the vertical it can cause the observed settling rates to double relative to readings obtained on a vertical rack.


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