Exposure to Parental Alcoholism During Childhood and Outcome in Adulthood: A Prospective Longitudinal Study

1986 ◽  
Vol 149 (5) ◽  
pp. 584-591 ◽  
Author(s):  
W. R. Beardslee ◽  
L. Son ◽  
G. E. Vaillant

The effects of children's exposure to parental alcoholism was assessed using records from an existing prospective 40-year longitudinal study of working-class families: 176 men who had grown up with an alcoholic parent or parents were compared with 230 men without such exposure. Degree of exposure to alcoholism in the childhood family environment was highly correlated in later life with alcohol use, alcoholism, time in jail, sociopathy, and death, but not with increased rates of unemployment, poor physical health, or measures of adult ego functioning. Most of the impairments observed occurred in those subjects who actually developed alcoholism. Exposure to alcoholism in the family environment and family history of alcoholism independently contributed to the later development of alcoholism.

1997 ◽  
Vol 9 (4) ◽  
pp. 855-879 ◽  
Author(s):  
JOHN R. OGAWA ◽  
L. ALAN SROUFE ◽  
NANCY S. WEINFIELD ◽  
ELIZABETH A. CARLSON ◽  
BYRON EGELAND

Dissociative behaviors and their relation to both the self and self-organization were examined using the developmental psychopathology perspective in a prospective longitudinal study of high-risk children. Participants were 168 young adults (n = 79 females, n = 89 males, age = 18–19 years) considered high-risk for poor developmental outcomes at birth due to poverty. The present study investigated whether trauma, sense of self, quality of early mother–child relationship, temperament, and intelligence were related to dissociative symptomatology measured at four times across 19 years. Findings were (a) age of onset, chronicity and severity of trauma were highly correlated and predicted level of dissociation; (b) both the avoidant and disorganized patterns of attachment were strong predictors of dissociation; (c) dissociation in childhood may be a more normative response to disruption and stress, while dissociation in adolescence and young adulthood may be more indicative of psychopathology; (d) preliminary support was found for a model proposed by G. Liotti that links disorganized attachment, later trauma, and dissociation in adulthood; and (e) strong support was found for N. Waller, F. W. Putnam, and E. B. Carlson's contention that psychopathological dissociation should not be viewed as the top end of a continuum of dissociative symptomatology, but as a separate taxon that represents an extreme deviation from normal development.


2021 ◽  
Author(s):  
Sharon S. Wang ◽  
Kate Walsh ◽  
James Janford Li

While maltreatment is clearly associated with an elevated risk for depression in later life, not all maltreated youths develop depression. This study examined whether maltreated youths who exhibit single-domain resilience (low levels of depression) simultaneously demonstrate multi-domain resilience in fundamental adaptive systems, including interpersonal functioning and violence, substance abuse/dependency, physical health, and socioeconomic domains. Trajectories of depression (across ages 13-32) in maltreated and non-maltreated individuals were modeled using data from the National Longitudinal Study of Adolescent to Adult Health. “Low,” “increasing,” and “declining” depression trajectories in both maltreated and non-maltreated individuals were identified. Yet, maltreated individuals in the “low” trajectory still had lower romantic relationship satisfaction, more exposure to intimate partner and sexual violence, more alcohol and marijuana abuse/dependency, and lower educational attainment relative to non-maltreated individuals in the “low” trajectory. Focusing on a single domain (i.e., depression) of resilience may obscure other impairments that maltreated children face in adulthood.


2017 ◽  
Vol 41 (S1) ◽  
pp. s237-s237
Author(s):  
D. Adamis ◽  
J. Williams ◽  
K. Finn ◽  
V. Melvin ◽  
D. Meagher ◽  
...  

IntroductionStudies of the association between blood BDNF levels and delirium are very few and have yielded mixed results.ObjectivesTo investigate the blood BDNF levels in the occurrence and recovery of delirium.MethodsProspective, longitudinal study. Participants were assessed twice weekly with MoCA, DRS-R98, APACHE-II. BDNF levels of the same were estimated with ELISA method. Delirium has been define as per DRS-98R (cut-off > 16) and recovery of delirium as at least two consequently assessments without delirium prior to discharge.ResultsNo differences in the levels of BDNF between those with delirium and those who never developed it. Excluding those who never developed delirium (n = 140), we analysed the effects of BDNF and the other variables on delirium resolution and recovery. Of the 58 remained with delirium in the subsequently observations (max = 8) some of them continue to be delirious until discharge or death (n = 39) while others recovered (n = 19). BDNF levels and MoCA scores were significantly associated with both delirium cases who became non-delirious (resolution) during the assessments and with overall recovery. BDNF (Wald χ2 = 11.652, df: 1 P = .001), for resolution. For recovery Wald χ2 = 7.155; df: 1, P = .007. No significant association was found for the other variables (APACHE-II, history of dementia, age or gender)ConclusionsBDNF do not have a direct effect in the occurrence of delirium but for those delirious of whom the levels are increased during the hospitalisation they are more likely to recover from delirium.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2004 ◽  
Vol 171 (4S) ◽  
pp. 38-38
Author(s):  
Benjamin K. Yang ◽  
Matthew D. Young ◽  
Brian Calingaert ◽  
Johannes Vieweg ◽  
Brian C. Murphy ◽  
...  

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