Effects of Substance Abuse on Ventricular and Sulcal Measures Assessed by Computerised Tomography

1991 ◽  
Vol 159 (2) ◽  
pp. 217-221 ◽  
Author(s):  
Nicola G. Cascella ◽  
Godfrey Pearlson ◽  
Dean F. Wong ◽  
Emmanuel Broussolle ◽  
Craig Nagoshi ◽  
...  
Keyword(s):  
Substance Abuse ◽  
Alcohol Consumption ◽  
Alcohol Use ◽  
Brain Atrophy ◽  
Brain Morphology ◽  
Computerised Tomography ◽  
Cocaine Use ◽  
Chronic Use ◽  
Effect Of Age ◽  
Normal Controls

Computerised tomography (CT) was used to assess the possible effects of substance abuse on brain morphology. Polydrug abusers had significantly wider third ventricles than normal controls, with a positive correlation between age and ventricle:brain ratio (VBR). Assuming no effect of age, estimated quantity of substance abuse was not significantly related to ventricular and sulcal measures, except that alcohol consumption correlated positively with VBR and severity of cocaine use correlated negatively with sulcal width. When age of the subjects was partialled out, alcohol use showed a tendency for association with VBR; however, severity of cocaine use did not remain a significant predictor of cortical sulcal width. The findings suggest that chronic use of alcohol, but not necessarily of other commonly abused substances, produces brain atrophy.

scholarly journals Alcohol use and brain morphology in adolescence: a longitudinal study in three different cohorts

2021 ◽  
Author(s):  
Hanan El Marroun ◽  
Eduard T. Klapwijk ◽  
Martijn Koevoets ◽  
Rachel M. Brouwer ◽  
Sabine Peters ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Alcohol Use ◽  
Brain Morphology

Cortical Thickness in Cocaine Use Disorder and its Relation to Age-Related Brain Atrophy

2021 ◽  
Vol 89 (9) ◽  
pp. S368-S369
Author(s):  
Lucca Pizzato Tondo ◽  
Wyllians Vendramini Borelli ◽  
Leonardo Melo Rothmann ◽  
Eduardo Leal-Conceição ◽  
Alexandre Rosa Franco ◽  
...  
Keyword(s):  
Cortical Thickness ◽  
Brain Atrophy ◽  
Cocaine Use ◽  
Age Related

Cheers together, but not alone: Peer drinking moderates alcohol consumption following interpersonal stress

2021 ◽  
pp. 026540752199604
Author(s):  
Hannah R. Hamilton ◽  
Stephen Armeli ◽  
Howard Tennen
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Academic Stress ◽  
Interpersonal Stress ◽  
Need To Belong ◽  
Effective Strategy ◽  
Social Drinking ◽  
Interpersonal Stressors ◽  
Peer Drinking

In view of the importance of the need to belong in motivating behavior, we examined whether interpersonal and academic stress differentially influence social and solitary alcohol consumption and whether social and solitary alcohol consumption differentially predict next-day interpersonal and academic stress. Based on research suggesting that drinking with friends is related to increased alcohol consumption following belongingness threat, we also examined whether peer consumption moderates associations between daily interpersonal stress and social drinking. Each day for 30 days, 1641 undergraduates reported stress, alcohol consumption, and peer consumption. Academic stress was related to lower levels of social and solitary alcohol consumption. Interpersonal stress was associated with greater social alcohol consumption, but only when students reported being around others who were drinking greater than average peer quantities. However, although social drinking was related to lower next-day academic stress, it was unrelated to next-day interpersonal stress. Findings are consistent with the notion that individuals’ perceptions of peers’ alcohol use might serve as a signal to join in this behavior to reduce belongingness threats associated with interpersonal stressors, although this may not be an effective strategy.

scholarly journals Alcohol Use Disorder among Patients Suffered from Road Collisions in a Vietnamese Delta Province

2019 ◽  
Vol 16 (13) ◽  
pp. 2423 ◽  
Author(s):  
Hai Minh Vu ◽  
Tung Thanh Tran ◽  
Giang Thu Vu ◽  
Cuong Tat Nguyen ◽  
Chau Minh Nguyen ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Drinking Behavior ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Problematic Drinking ◽  
Current Context ◽  
Educational Campaign ◽  
Causes Of Deaths ◽  
The Relationship

Traffic collisions have continuously been ranked amongst the top causes of deaths in Vietnam. In particular, drinking has been recognized as a major factor amplifying the likelihood of traffic collisions in various settings. This study aims to examine the relationship between alcohol use and traffic collisions in the current context of Vietnam. A cross-sectional study was conducted on 413 traffic collisions patients in six health facilities in the Thai Binh Province to investigate the level of alcohol consumption and identify factors influencing alcohol use among these patients. The Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) scale was used to determine the problematic drinking behavior of the participants. The percentage of patients having problematic drinking was more than 30%. Being male, having a high household income, and working as farmer/worker were risk factors for alcohol abuse. People causing accidents and patients with a traumatic brain injury had a higher likelihood of drinking alcohol before the accidents. This study highlights the necessity of more stringent laws on reducing drink-driving in Vietnam. In addition, more interventions, especially those utilizing mass media like educational campaign of good behavior on social networks, are necessary to reduce alcohol consumption in targeted populations in order to decrease the prevalence and burden of road injuries.

Nalmefene against alcohol use disorder: A report of one case

2017 ◽  
Vol 41 (S1) ◽  
pp. s866-s866
Author(s):  
M. Juncal Ruiz ◽  
O. Porta Olivares ◽  
L. Sánchez Blanco ◽  
R. Landera Rodríguez ◽  
M. Gómez Revuelta ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Opioid Receptor ◽  
Treatment Option ◽  
Withdrawal Syndrome ◽  
Alcohol Use Disorder ◽  
Alcohol Intake ◽  
Family Relationship ◽  
Heavy Drinking ◽  
Alcohol Withdrawal Syndrome

IntroductionAlcohol consumption represents a significant factor for mortality in the world: 6.3% in men and 1.1% in women. Alcohol use disorder is also very common: 5.4% in men and 1.5% in women. Despite its high frequency and the seriousness of this disorder, only 8% of all alcohol-dependents are ever treated. One potentially interesting treatment option is oriented toward reducing alcohol intake.AimsTo describe one case who has improved his alcohol consumption after starting treatment with nalmefene, an opioid receptor antagonist related to naltrexone.MethodsA 35-year-old male with alcohol use disorder since 2001 came to our consult in November 2015. He was in trouble with his family and he had a liver failure. We offer a new treatment option with nalmefene 18 mg to reduce alcohol consumption.ResultsBefore to start nalmefene he drank 21 drinks/week. Six-month later, he decreased alcohol intake until 5 drinks/week with better family relationship and liver function. After starting nalmefene he complained of nausea, so we recommend to take the middle of the pill for next 7 days. After this time he returned to take one pill with good tolerance and no more side effects or withdrawal syndrome.ConclusionsNalmefene appears to be effective and safe in reducing heavy drinking and in preventing alcohol withdrawal syndrome due to its opioid receptor antagonism. This case suggests nalmefene is a potential option to help patients, who do not want or cannot get the abstinence, in reducing their alcohol consumption.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Towards the characterization and validation of alcohol use disorder subtypes: integrating consumption and symptom data

2013 ◽  
Vol 44 (1) ◽  
pp. 143-159 ◽  
Author(s):  
K. M. Jackson ◽  
K. K. Bucholz ◽  
P. K. Wood ◽  
D. Steinley ◽  
J. D. Grant ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Model Comparison ◽  
Latent Class ◽  
Common Factor ◽  
Hybrid Approaches ◽  
Epidemiologic Survey ◽  
Alcohol Involvement ◽  
Best Fitting

BackgroundThere is evidence that measures of alcohol consumption, dependence and abuse are valid indicators of qualitatively different subtypes of alcohol involvement yet also fall along a continuum. The present study attempts to resolve the extent to which variations in alcohol involvement reflect a difference in kindversusa difference in degree.MethodData were taken from the 2001–2002 National Epidemiologic Survey of Alcohol and Related Conditions. The sample (51% male; 72% white/non-Hispanic) included respondents reporting past 12-month drinking at both waves (wave 1:n = 33644; wave 2:n = 25186). We compared factor mixture models (FMMs), a hybrid of common factor analysis (FA) and latent class analysis (LCA), against FA and LCA models using past 12-month alcohol use disorder (AUD) criteria and five indicators of alcohol consumption reflecting frequency and heaviness of drinking.ResultsModel comparison revealed that the best-fitting model at wave 1 was a one-factor four-class FMM, with classes primarily varying across dependence and consumption indices. The model was replicated using wave 2 data, and validated against AUD and dependence diagnoses. Class stability from waves 1 to 2 was moderate, with greatest agreement for the infrequent drinking class. Within-class associations in the underlying latent factor also revealed modest agreement over time.ConclusionsThere is evidence that alcohol involvement can be considered both categorical and continuous, with responses reduced to four patterns that quantitatively vary along a single dimension. Nosologists may consider hybrid approaches involving groups that vary in pattern of consumption and dependence symptomatology as well as variation of severity within group.

scholarly journals Negative Affect, Alcohol Consumption, and Female-to-Male Intimate Partner Violence: A Daily Diary Investigation

Partner Abuse ◽  
2013 ◽  
Vol 4 (3) ◽  
pp. 332-355 ◽  
Author(s):  
Cory A. Crane ◽  
Christopher I. Eckhardt
Keyword(s):  
Intimate Partner Violence ◽  
Alcohol Consumption ◽  
Alcohol Use ◽  
Negative Affect ◽  
Partner Violence ◽  
Male Partner ◽  
Intimate Partner ◽  
College Age ◽  
The Status ◽  
Daily Risk

Although research suggests that both negative affect and alcohol use are related to the risk of intimate partner violence (IPV) in male samples, less is known about the status of these risk factors in female samples. Forty-three college-age females who reported a recent history of IPV perpetration submitted 6 weeks of Online daily reports pertaining to their levels of negative affect, alcohol consumption habits, and the occurrence of both male-to-female partner violence (MFPV) and female-to-male partner violence (FMPV). Results indicated that negative affect significantly predicted increases in the daily risk of FMPV. MFPV also significantly predicted FMPV risk. Alcohol consumption failed to predict FMPV perpetration on both levels of analysis. Results are discussed in terms of prevailing models of alcohol use, negative affect, and IPV.

scholarly journals The Association between Dating Apps and Alcohol Consumption in an Italian Sample of Active Users, Former Users, and Non-Users

2021 ◽  
Vol 10 (7) ◽  
pp. 249
Author(s):  
Luca Flesia ◽  
Valentina Fietta ◽  
Carlo Foresta ◽  
Merylin Monaro
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Ad Hoc ◽  
Multiple Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Dating Apps ◽  
Regular Consumption ◽  
And Gender ◽  
The Relationship

To date, the relationship between alcohol use and dating app use has been investigated mostly in conjunction with sexual activities and in homosexual men. For this reason, the aim of this study was to explore the association between dating app use and alcohol consumption among the general population. A cross-sectional study was conducted including app users, non-users, and former users: 1278 respondents completed an online ad hoc questionnaire assessing dating app use, motivations for installing dating apps, alcohol use, and demographics. Multiple logistic regression analysis was run to investigate the association between dating app use, demographic features, and alcohol consumption. Whereas educational level, age, and gender significantly contributed to the regular consumption of alcohol, dating app use did not account for a significant amount of variance between regular and not regular drinkers. However, people who installed and used dating apps with the motivation of searching for sexual partners were more likely to be regular drinkers. Among the active users, heavy app users were less likely to drink regularly. The study indicates that underlying factors (sexual aspects, motives for using the apps) and the intensity of using the apps may mediate the relationship between dating app use and alcohol use.

Abstract 12385: Past Alcohol Consumption and Incident Atrial Fibrillation

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Shalini Dixit ◽  
Alvaro Alonso ◽  
Elsayed Z Soliman ◽  
Lin Y Chen ◽  
Gregory M Marcus
Keyword(s):  
Atrial Fibrillation ◽  
Alcohol Consumption ◽  
Alcohol Use ◽  
Population Based ◽  
Self Report ◽  
Atherosclerosis Risk In Communities ◽  
Increased Risk ◽  
Before And After ◽  
Dietary Intake Assessment ◽  
Aric Study

Introduction: Although current alcohol consumption appears to be a risk factor for incident atrial fibrillation (AF), limitations related to self-reported alcohol use and confounding in observational studies limit the certainty of conclusions regarding causality. Whether cessation of alcohol consumption can protect against incident AF remains unknown. Methods: We examined all participants in the Atherosclerosis Risk in Communities (ARIC) study, a population-based cohort of 15,792 men and women aged 45-65, without prevalent AF. Past alcohol consumption was assessed via self-report during the baseline dietary intake assessment. Cases of incident AF were ascertained via study ECGs, hospital discharge ICD-9 codes, and death certificates. Results: Among 15,262 participants with complete survey data, 2,898 (19.0%) were former drinkers. During an average follow-up of 17.4 years, there were 380 cases of incident AF in former consumers. Both before and after adjustment for potential confounders, a longer duration of alcohol abstinence was associated with a lower risk of developing AF; previously consuming alcohol for a longer duration and consuming a greater quantity of alcohol were each associated with a higher risk of developing AF (Table). Conclusions: Among former drinkers, the number of years of drinking and the amount of alcohol consumed may each confer an increased risk of AF. Given that a longer duration of abstinence was associated with a decreased risk of AF, modification of alcohol use could potentially play a role in AF prevention.

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