Perioperative blood transfusions and cancer recurrence.

1988 ◽  
Vol 6 (8) ◽  
pp. 1348-1354 ◽  
Author(s):  
H S Wu ◽  
A G Little
Keyword(s):  
Natural Killer Cells ◽  
Acquired Immunodeficiency Syndrome ◽  
Cancer Recurrence ◽  
Cancer Surgery ◽  
The Other ◽  
Blood Transfusions ◽  
Suppressor T Lymphocytes ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Worse Prognosis

This collective review addresses the issue of transfusion-induced immunosuppression as it relates to patients undergoing cancer surgery. Patients receiving perioperative blood transfusions have a significantly worse prognosis than patients undergoing cancer surgery without a perioperative transfusion. It is thought that this is because transfusions produce a nonspecific immunosuppression by increasing the number and/or activity of suppressor T lymphocytes, decreasing the number of natural killer cells, and inducing anti-idiotypic antibodies. This risk, particularly when considered with the other risks of transfusion such as hepatitis or the acquired immunodeficiency syndrome (AIDS), suggests that criteria for transfusion of these patients should be stringent and related to an unequivocal need for replenishment of RBCs.

scholarly journals Trypanosoma cruzi meningoencephalitis and myocarditis in a patient with acquired immunodeficiency syndrome

1993 ◽  
Vol 35 (2) ◽  
pp. 205-208 ◽  
Author(s):  
Ademir Rocha ◽  
Marcelo S. Ferreira ◽  
Sergio A. Nishioka ◽  
Marcos Silva ◽  
Marcius K. N. Burgarelli ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Differential Diagnosis ◽  
Chagas Disease ◽  
Acquired Immunodeficiency Syndrome ◽  
The Other ◽  
Post Mortem ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Male Heterosexual

We report the case of a 52-year-old male heterosexual patient with acquired immunodeficiency syndrome (AIDS) and reactivation of Chagas' disease manifested by meningoencephalitis and myocarditis, diagnosed post-mortem. Unexplained reactivation of Chagas' disease should be included among the diagnostic criteria of AIDS in human immunodeficiency virus positive patients. On the other hand, AIDS should be considered in the differential diagnosis of patients with unexplained reactivation of Chagas' disease.

scholarly journals Specific translocations characterize Burkitt's-like lymphoma of homosexual men with the acquired immunodeficiency syndrome

Blood ◽  
1983 ◽  
Vol 61 (6) ◽  
pp. 1265-1268 ◽  
Author(s):  
RS Chaganti ◽  
SC Jhanwar ◽  
B Koziner ◽  
Z Arlin ◽  
R Mertelsmann ◽  
...  
Keyword(s):  
Acquired Immunodeficiency Syndrome ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
The Other ◽  
Homosexual Men ◽  
Immunoglobulin Genes ◽  
Chromosome Translocations ◽  
Cytogenetic Studies ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Abstract A Burkitt's-like B-cell lymphoma (BLL) has recently been shown to be associated with the acquired immunodeficiency syndrome (AIDS), which affects homosexual men. We report cytogenetic studies of two BLL tumors in homosexual men. Both tumors had chromosome translocations characteristic of Burkitt's lymphoma (BL), one the t(8;14) and the other the t(8;22). The pathway of lymphomagenesis in this disorder is discussed in the light of recent data on chromosome change and localization of immunoglobulin genes and oncogenes.

scholarly journals Specific translocations characterize Burkitt's-like lymphoma of homosexual men with the acquired immunodeficiency syndrome

Blood ◽  
1983 ◽  
Vol 61 (6) ◽  
pp. 1265-1268 ◽  
Author(s):  
RS Chaganti ◽  
SC Jhanwar ◽  
B Koziner ◽  
Z Arlin ◽  
R Mertelsmann ◽  
...  
Keyword(s):  
Acquired Immunodeficiency Syndrome ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
The Other ◽  
Homosexual Men ◽  
Immunoglobulin Genes ◽  
Chromosome Translocations ◽  
Cytogenetic Studies ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

A Burkitt's-like B-cell lymphoma (BLL) has recently been shown to be associated with the acquired immunodeficiency syndrome (AIDS), which affects homosexual men. We report cytogenetic studies of two BLL tumors in homosexual men. Both tumors had chromosome translocations characteristic of Burkitt's lymphoma (BL), one the t(8;14) and the other the t(8;22). The pathway of lymphomagenesis in this disorder is discussed in the light of recent data on chromosome change and localization of immunoglobulin genes and oncogenes.

Paraproteinemia in patients with acquired immunodeficiency syndrome (AIDS) or lymphadenopathy syndrome (LAS).

1985 ◽  
Vol 31 (7) ◽  
pp. 1224-1226 ◽  
Author(s):  
K Heriot ◽  
A E Hallquist ◽  
R H Tomar
Keyword(s):  
B Cell ◽  
Immune Regulation ◽  
Acquired Immunodeficiency Syndrome ◽  
The Other ◽  
Light Chains ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
And Function ◽  
Relationship Of ◽  
The Relationship

Abstract Eight of 15 patients with acquired immunodeficiency syndrome (AIDS) and six of nine patients with lymphadenopathy syndrome (LAS) had paraproteins in their sera. Twelve of these 14 were IgG kappa; the other two had no demonstrable light chains. The relationship of the paraprotein to the pathogenesis of AIDS is not clear, but we discuss its relation to derangements of B-cell immune regulation and function and to B-cell tumors in AIDS patients.

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