Antitumor or Wound Healing Actions of Natural Products through Inhibiting or Enhancing Angiogenesis

2011 ◽  
pp. 265-298
Author(s):  
Yoshiyuki Kimura
Keyword(s):  
Wound Healing ◽  
Natural Products

Natural Products as Wound Healing Agents

2021 ◽  
pp. 77-94
Author(s):  
Eman A. Khalil ◽  
Sara S. Abou-Zekry ◽  
Diana G. Sami ◽  
Ahmed Abdellatif
Keyword(s):  
Wound Healing ◽  
Natural Products

Perspective on the application of medicinal plants and natural products in wound healing: A mechanistic review

2021 ◽  
pp. 105841
Author(s):  
Omid Yazarlu ◽  
Mehrdad Iranshahi ◽  
Hamid Reza Khayat Kashani ◽  
Sara Reshadat ◽  
Solomon Habtemariam ◽  
...  
Keyword(s):  
Wound Healing ◽  
Natural Products ◽  
Medicinal Plants

Cosmeceuticals and natural products: wound healing

2009 ◽  
Vol 27 (5) ◽  
pp. 502-506 ◽  
Author(s):  
Stephen C. Davis ◽  
Robert Perez
Keyword(s):  
Wound Healing ◽  
Natural Products

scholarly journals Wound Healing and the Use of Medicinal Plants

2019 ◽  
Vol 2019 ◽  
pp. 1-30 ◽  
Author(s):  
Aleksandra Shedoeva ◽  
David Leavesley ◽  
Zee Upton ◽  
Chen Fan
Keyword(s):  
Wound Healing ◽  
Natural Products ◽  
Curcuma Longa ◽  
Extended Period ◽  
Centella Asiatica ◽  
Dermal Fibroblasts ◽  
Cutaneous Wound Healing ◽  
Clinical Value ◽  
Cutaneous Wound ◽  
Traditional Medicines

Cutaneous wound healing is the process by which skin repairs itself. It is generally accepted that cutaneous wound healing can be divided into 4 phases: haemostasis, inflammation, proliferation, and remodelling. In humans, keratinocytes re-form a functional epidermis (reepithelialization) as rapidly as possible, closing the wound and reestablishing tissue homeostasis. Dermal fibroblasts migrate into the wound bed and proliferate, creating “granulation tissue” rich in extracellular matrix proteins and supporting the growth of new blood vessels. Ultimately, this is remodelled over an extended period, returning the injured tissue to a state similar to that before injury. Dysregulation in any phase of the wound healing cascade delays healing and may result in various skin pathologies, including nonhealing, or chronic ulceration. Indigenous and traditional medicines make extensive use of natural products and derivatives of natural products and provide more than half of all medicines consumed today throughout the world. Recognising the important role traditional medicine continues to play, we have undertaken an extensive survey of literature reporting the use of medical plants and plant-based products for cutaneous wounds. We describe the active ingredients, bioactivities, clinical uses, formulations, methods of preparation, and clinical value of 36 medical plant species. Several species stand out, including Centella asiatica, Curcuma longa, and Paeonia suffruticosa, which are popular wound healing products used by several cultures and ethnic groups. The popularity and evidence of continued use clearly indicates that there are still lessons to be learned from traditional practices. Hidden in the myriad of natural products and derivatives from natural products are undescribed reagents, unexplored combinations, and adjunct compounds that could have a place in the contemporary therapeutic inventory.

The effects of medicinal herbs and marine natural products on wound healing of cutaneous leishmaniasis: A systematic review

2021 ◽  
pp. 105235
Author(s):  
Elahe Tajbakhsh ◽  
Ali Khamesipour ◽  
Seyed Reza Hosseini ◽  
Neda Kosari ◽  
Shima Shantiae ◽  
...  
Keyword(s):  
Systematic Review ◽  
Wound Healing ◽  
Natural Products ◽  
Cutaneous Leishmaniasis ◽  
Marine Natural Products ◽  
Medicinal Herbs

scholarly journals Natural Products and/or Isolated Compounds on Wound Healing

2019 ◽  
Vol 2019 ◽  
pp. 1-3 ◽  
Author(s):  
Christian Agyare ◽  
Abidemi J. Akindele ◽  
Vanessa Steenkamp
Keyword(s):  
Wound Healing ◽  
Natural Products

scholarly journals Anti-Inflammatory, Antioxidant and Wound Healing Properties of Cyanobacteria from Thermal Mud of Balaruc-les-Bains, France: A Multi-Approach Study

2020 ◽  
Author(s):  
Justine Demay ◽  
Sébastien Halary ◽  
Adeline Knittel-Obrecht ◽  
Pascal Villa ◽  
Charlotte Duval ◽  
...  
Keyword(s):  
Wound Healing ◽  
Natural Products ◽  
Ecological Niche ◽  
Microbial Biofilm ◽  
Specific Adaptation ◽  
Bioactive Natural Products ◽  
Anti Inflammatory

Background: The Balaruc-les-Bains’ thermal mud was found to be colonized predominantly by microorganisms, with cyanobacteria constituting the primary organism in the microbial biofilm observed on the mud surface. The success of cyanobacteria in colonizing this specific ecological niche can be explained in part by their taxa-specific adaptation capacities, and also the diversity of bioactive natural products that they synthesize. This array of components has physiological and ecological properties that may be exploited for various applications.

NATURAL PRODUCTS IN WOUND HEALING: NANO-TECHNOLOGY BASED APPROACHES

INDIAN DRUGS ◽  
2021 ◽  
Vol 57 (11) ◽  
pp. 7-14
Author(s):  
Harshad S Kapare ◽  
◽  
Sarika R. Metkar ◽  
Shweta V. Wakalkar
Keyword(s):  
Drug Delivery ◽  
Wound Healing ◽  
Natural Products ◽  
Chemical Compounds ◽  
Anatomical Structure ◽  
Therapeutic Activity ◽  
Nano Technology ◽  
Enhanced Solubility ◽  
Biopharmaceutical Properties ◽  
Wound Healing Activity

Wound is a disruption of the normal anatomical structure and the tissue function. The wound healing or repair is an orderly process which involves multiple phases characterized by inflammation, proliferation and remodeling. Natural products, which are derived from herbs and animals, constitute several chemical compounds which are proven for great wound healing potential. The major issue in therapeutic use of these natural products is the solubility constraint due to high lipophilicity and hence it hampers bioavailability and pharmacological effect. Nanotechnology based approaches are well proven as an approach for solubility enhancement and thus found to be useful for improvement of the efficacy and therapeutic activity. In this review different potential natural products known for promoting angiogenesis and wound healing activity by various mechanisms are summarized with emphasis on the various nanotechnology based approaches developed as a drug delivery system for these products to achieve enhanced solubility and improved its biopharmaceutical properties.

scholarly journals FTIR analysis and quantification of phenols and flavonoids of five commercially available plants extracts used in wound healing

2016 ◽  
Vol 21 (3) ◽  
pp. 767-779 ◽  
Author(s):  
Renata Nunes Oliveira ◽  
Maurício Cordeiro Mancini ◽  
Fernando Cabral Salles de Oliveira ◽  
Thayse Marques Passos ◽  
Brid Quilty ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Wound Healing ◽  
Natural Products ◽  
Phenolic Compounds ◽  
Antioxidant Activities ◽  
The Other ◽  
Ftir Analysis ◽  
Flavonoid Content ◽  
Dragon’S Blood ◽  
Brazilian Propolis

ABSTRACT Natural products are used in wound healing in order to prevent infection. Propolis is a well known antimicrobial with phenolic compounds and flavonoid content which vary according to the propolis origin. Besides propolis (from both Brazilian and UK sources), pomegranate, dragon's blood and sage are possible antimicrobials to be used in biomaterials. The goal of this work was to analyze the amount of phenols and flavonoid compounds in these natural products, their antioxidant activities and the bonds present by FTIR. The FTIR analysis revealed the presence of active compounds in all drug samples. The phenols quantification showed that Brazilian propolis was rich in phenols compared to the other drugs, followed by pomegranate and UK propolis. UK propolis was the most rich in flavonoids, which is expected on account of its origin. Pomegranate, UK propolis and Dragon's blood presented the highest antioxidant activity. All samples presented antioxidant activity > 82%.

scholarly journals Wound Healing Properties of Selected Natural Products

2018 ◽  
Vol 15 (11) ◽  
pp. 2360 ◽  
Author(s):  
Nurul Ibrahim ◽  
Sok Wong ◽  
Isa Mohamed ◽  
Norazlina Mohamed ◽  
Kok-Yong Chin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Natural Products ◽  
Repair Process ◽  
Impaired Wound Healing ◽  
Complex Process ◽  
Synthesis Properties ◽  
Medicinal Properties ◽  
Underlying Diseases

Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.

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