Surgical sutures and needles

2006 ◽  
pp. 356-360
Keyword(s):  
Author(s):  
Kant Y. Lin ◽  
Heidi-Marie A. Farinholt ◽  
Vikram R. Reddy ◽  
Richard Edlich ◽  
George T. Rodeheaver

2010 ◽  
Vol 5 (4) ◽  
pp. 155892501000500 ◽  
Author(s):  
Hang Liu ◽  
Karen K. Leonas ◽  
Yiping Zhao

Poly(εepsilon;-caprolactone) (PCL) electrospun fibers containing ampicillin sodium salt have been produced and twisted into nanofiber yarns. The fiber diameters and crystallinity, the in vitro antimicrobial properties of the yarns, and the in vitro release of ampicillin from yarns containing various ampicillin concentrations are studied. Decreased fiber diameters and reduced diameter variation are observed with the addition of ampicillin salt into the polymer solution. The results from the zone of inhibition test of the yarns against both gram-positive Staphylococcus aureus and gram-negative Klebsiella pneumoniae indicate that the released ampicillin retains its effectiveness after the production processes, therefore the as-spun yarns are antimicrobial active. A burst release of ampicillin from the yarns has been observed in the first hour, and the release is almost completed in 96 hours. The burst release is believed to be due to the low compatibility of ampicillin with PCL, the accumulation of ampicillin on fiber surface and the small fiber diameters. An empirical release model is developed to describe the release profile. The results indicate that the electrospun nanofibers yarns will have a great potential to be used for biomaterials, such as surgical sutures, to decrease the surgical site infection rate.


BIOspektrum ◽  
2021 ◽  
Vol 27 (2) ◽  
pp. 202-204
Author(s):  
Myra N. Chávez ◽  
Benedikt Fuchs ◽  
Jörg Nickelsen

AbstractWe have recently proposed a novel strategy named photosynthetic tissue engineering to overcome clinical problems due to hypoxia. The idea is based on transgenic photoautotrophic microorganisms that produce oxygen and at the same time secrete functional recombinant proteins into tissues. In particular, the unicellular green alga Chlamydomonas reinhardtii has successfully been used to boost the regenerative potential of several biomedical devices, such as dermal scaffolds and surgical sutures.


2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
Joshua Burke ◽  
Jack Helliwell ◽  
Mikolaj Kowal ◽  
David Jayne

Abstract Aim Platelet-rich fibrin (PRF) is a three-dimensional fibrin scaffold with associated platelets and leukocytes which releases high quantities of growth factors over a sustained period of time. PRF has shown promising clinical results in promoting wound healing and tissue regeneration. The aims of this feasibility study were to establish optimal spinning methods for production of PRF, to quantify the production of vascular endothelial growth factor (VEGF) by PRF and to explore new vehicles of clinical PRF delivery. Method Assessment of optimal production involved comparisons between Protocol 1 (EDTA bottle) and Protocol 2 (no additive) at three different centrifugation forces: 400g, 1000g and 1700g. VEGF production was analysed using ELISA with varied incubation periods and PRF plug segments. Novel methods for PRF delivery were explored using surgical sutures and a Zimmer® Skin Graft Mesher. Results Protocol 2 demonstrated shorter average time to blood draw (9.8s compared to 13.6s) and to centrifuge (25.5s compared to 33.1s) with a decreased range of values. All PRF segments exhibited a positive correlation between incubation time and amount of VEGF produced with the bottom segments producing on average more VEGF. A segment of the fibrin plug was successfully secured on a suture and meshed in a 1:1.5 ratio. Conclusions PRF production can be optimised using blood bottles with no additive and high centrifugation forces. VEGF production by PRF peaks at 120 hours with the bottom PRF segment exhibiting the highest rate of production. The first description of a PRF mesh enables new clinical applications.


1996 ◽  
Vol 14 (2) ◽  
pp. 201-204 ◽  
Author(s):  
Christine C. Annunziata ◽  
John G. Thacker ◽  
Julia A. Woods ◽  
Richard F. Edlich

2018 ◽  
Vol 89 (16) ◽  
pp. 3291-3302 ◽  
Author(s):  
Shuqiang Liu ◽  
Mingfang Liu ◽  
Gaihong Wu ◽  
Xiaofang Zhang ◽  
Juanjuan Yu ◽  
...  

Polylactic acid (PLA) surgical sutures are a new type of absorbable sutures that can be degraded and absorbed in the body. However, there is high hydrophobicity for the surface of PLA sutures, which leads to poor biocompatibility and cellular affinity. In order to increase the hydrophilicity, the PLA sutures were etched by lipase firstly, and then grafted with chitosan. The results indicate that the optimal conditions of treating PLA sutures by lipase were as follows: 45℃ reaction temperature, 4.5 g/L concentration of lipase and 8 h reaction time. The sutures were etched by lipase and then formed some grooves and a number of hydroxyl (-OH) bonds, which led to increased surface area and hydrophilicity, but a drop in mass and strength. The optimal conditions of grafting chitosan onto PLA sutures were as follows: 4 h reaction time and 3 g/L concentration of chitosan. The chitosan grafted and loaded on the surface of PLA sutures, and in some areas of the sutures the chitosan reunited, which led to a rough surface and large friction coefficient. Finally, the hydrophilicity of the PLA sutures, treated by lipase and then grafted with chitosan, was greatly improved.


2020 ◽  
Vol 22 (98) ◽  
pp. 63-68
Author(s):  
A. D. Stepanov

Surgical access for ovariohysterectomy in bitches through the right lateral abdominal wall with an incision in its upper third in the direction from the anterior edge of the macula to the fourth nipple of the corresponding side of the breast is proposed. The article presents the results of studies obtained when used for the purpose of ovariohysterectomy in bitches of operative access through the right lateral and ventral abdominal wall. Research work was conducted on healthy mature bitches. The operations were performed in the area of the right lateral abdominal wall and in the umbilical region. On the lateral abdominal wall, an oblique-vertical incision was used at the border of the inguinal and iliac areas in the direction from the anterior edge of the macula to the fourth nipple of the corresponding side of the breast. The ventral abdominal wall was cut along the white line. It was found that when performing ovariohysterectomy in bitches using the proposed surgical access through the right lateral abdominal wall with a smaller wound size (P < 0.05), the duration of the operation and the healing period correspond to those when using median laparotomy. It is proved that operative access with oblique-vertical incision in the area of the right lateral abdominal wall at the border of the groin and anus during ovariohysterectomy in bitches provides favorable opportunities for surgical reception and closure of the surgical wound. The number of surgical sutures for sutures on the abdominal wall is less than in the case of ventral access (P < 0.01). It is also noted that in ovariohysterectomy in bitches, operative access through the right lateral abdominal wall with an incision in the direction from the anterior edge of the macula to the fourth nipple of the corresponding side of the breast may be recommended as an alternative access through the white line of the abdomen.


10.3823/2626 ◽  
2020 ◽  
Vol 13 ◽  
Author(s):  
Viviane Moura Leite ◽  
Caroline Freitas de Souza Plácido ◽  
Carolina Lucena Veloso Gusmão ◽  
Evelyne Pessoa Soriano ◽  
Adriana Conrado Almeida ◽  
...  

Background The aim of this study was to analyze the extent and uniqueness of anatomical variations of the sternum bone, to assess its applicability for forensic analysis, especially for individual human identification. Methods and Findings Evaluations involved 501 computer tomography scans performed at the Medical Radiology Center, Manaus city, Amazonas, Brazil, and 427 skeletons belonging to the Collection of Identified Human Skeletons of the Center for Studies in Forensic Anthropology (CEAF), of the University of Pernambuco (UPE), Pernambuco, Brazil.  Forms of morphological variations were evaluated, including the presence of foramina, fissures, and incomplete total or partial fusions, as well as forms of xiphoid process termination, and the presence of surgical sutures. Overall, summing computed tomographic images and skeletons, the sternal foramen was present in some 23% of samples, with a greater proportion in males (14%), while in females the frequency was 8.6%. Conclusions The qualitative analysis of the sternum bone is simple to apply and represents an important potential source of information in a human identification process.


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